Cell Line : CL-40

Cellosaurus Index : CVCL_1982
Cellosaurus ID : CL-40

CCLE Name : CL40_LARGE_INTESTINE
CTRP1 Name , CTRP2 Name : CL40

Cancer Type : large_intestine
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
CL-40 (-)-gallocatechin-3-monogallate CTRP1 2.3125 296.0000
CL-40 10-DEBC CTRP1 0.6250 80.0000
CL-40 16-beta-bromoandrosterone CTRP1 0.2891 37.0000
CL-40 16,16-dimethylprostaglandin-E2 CTRP1 0.2604 33.3330
CL-40 1S,3R-RSL-3 CTRP1 0.0312 4.0000
CL-40 2-bromopyruvate CTRP1 4.1667 533.3300
CL-40 2-fluoropalmitic acid CTRP1 1.1562 148.0000
CL-40 2,4-dideoxy-DC-45-A2 CTRP1 0.0163 2.0833
CL-40 3-aminobenzamide CTRP1 0.9564 122.4100
CL-40 3-chloro-L-alanine CTRP1 0.0163 2.0833
CL-40 4-IPP CTRP1 1.0417 133.3300
CL-40 4-methylfasudil CTRP1 1.0417 133.3300
CL-40 6-diazo-5-oxo-L-norleucine CTRP1 1.0417 133.3300
CL-40 7-nitroindazole CTRP1 2.0833 266.6700
CL-40 AA-COCF3 CTRP1 2.0833 266.6700
CL-40 ABT-751 CTRP1 0.2604 33.3330
CL-40 ABT737 CTRP1 0.2891 37.0000
CL-40 AC55649 CTRP1 0.2604 33.3330
CL-40 AG14361 CTRP1 0.6510 83.3330
CL-40 AGK-2 CTRP1 0.2604 33.3330
CL-40 Alda-1 CTRP1 1.0417 133.3300
CL-40 AM-580 CTRP1 4.1667 533.3300
CL-40 ASN 05257430 CTRP1 0.2891 37.0000
CL-40 austocystin D CTRP1 0.2891 37.0000
CL-40 avrainvillamide CTRP1 0.2604 33.3330
CL-40 AZD-7545 CTRP1 0.5781 74.0000
CL-40 B02 CTRP1 1.0417 133.3300
CL-40 batimastat CTRP1 1.1562 148.0000
CL-40 Bax channel blocker CTRP1 0.2604 33.3330
CL-40 BEC CTRP1 2.0833 266.6700
CL-40 BI-2536 CTRP1 0.2604 33.3330
CL-40 BIBR-1532 CTRP1 2.0833 266.6700
CL-40 BIX-01294 CTRP1 0.2604 33.3330
CL-40 blebbistatin CTRP1 1.0417 133.3300
CL-40 BML-259 CTRP1 2.0833 266.6700
CL-40 BMS-191011 CTRP1 0.2604 33.3330
CL-40 BMS-299897 CTRP1 0.2604 33.3330
CL-40 BMS-536924 CTRP1 0.2891 37.0000
CL-40 BMS-641988 CTRP1 0.2891 37.0000
CL-40 BMS-754807 CTRP1 0.2604 33.3330
CL-40 Bortezomib CTRP1 0.0010 0.1300
CL-40 BRD0713 CTRP1 0.6250 80.0000
CL-40 BRD1429 CTRP1 0.2604 33.3330
CL-40 BRD1566 CTRP1 0.2683 34.3400
CL-40 BRD1812 CTRP1 0.2604 33.3330
CL-40 BRD2296 CTRP1 0.2604 33.3330
CL-40 BRD2572 CTRP1 0.6250 80.0000
CL-40 BRD2762 CTRP1 0.6250 80.0000
CL-40 BRD32048 CTRP1 0.2604 33.3330
CL-40 BRD4046 CTRP1 0.6250 80.0000
CL-40 BRD4132 CTRP1 1.2500 160.0000
CL-40 BRD4354 CTRP1 0.2604 33.3330
CL-40 BRD4372 CTRP1 0.6250 80.0000
CL-40 BRD4470 CTRP1 0.2604 33.3330
CL-40 BRD4479 CTRP1 0.1823 23.3330
CL-40 BRD4770 CTRP1 0.2604 33.3330
CL-40 BRD55319 CTRP1 0.2891 37.0000
CL-40 BRD5586 CTRP1 0.2604 33.3330
CL-40 BRD5802 CTRP1 0.6250 80.0000
CL-40 BRD6150 CTRP1 0.6250 80.0000
CL-40 BRD6340 CTRP1 0.3125 40.0000
CL-40 BRD63610 CTRP1 0.0081 1.0417
CL-40 BRD6368 CTRP1 0.2604 33.3330
CL-40 BRD6413 CTRP1 0.2604 33.3330
CL-40 BRD6430 CTRP1 0.2604 33.3330
CL-40 BRD6825 CTRP1 0.6250 80.0000
CL-40 BRD7137 CTRP1 0.2604 33.3330
CL-40 BRD8097 CTRP1 0.6250 80.0000
CL-40 BRD8418 CTRP1 0.6250 80.0000
CL-40 BRD8958 CTRP1 0.5208 66.6670
CL-40 BRD9571 CTRP1 0.6250 80.0000
CL-40 BRD9647 CTRP1 0.5208 66.6670
CL-40 BRD9658 CTRP1 0.6250 80.0000
CL-40 BRD9876 CTRP1 1.0417 133.3300
CL-40 brefeldin A CTRP1 0.0023 0.2890
CL-40 BX795 CTRP1 0.2604 33.3330
CL-40 capsaicin CTRP1 4.1667 533.3300
CL-40 carbamazepine CTRP1 2.5000 320.0000
CL-40 CAY10594 CTRP1 0.5208 66.6670
CL-40 CAY10618 CTRP1 0.2604 33.3330
CL-40 CCT036477 CTRP1 0.2604 33.3330
CL-40 CD-1530 CTRP1 1.0417 133.3300
CL-40 CD-437 CTRP1 0.2891 37.0000
CL-40 cerulenin CTRP1 1.1562 148.0000
CL-40 chaetocin CTRP1 0.0020 0.2600
CL-40 CHEMBL1222381 CTRP1 2.0833 266.6700
CL-40 CHEMBL374350 CTRP1 0.2604 33.3330
CL-40 CHEMBL399379 CTRP1 2.0833 266.6700
CL-40 CHIR-99021 CTRP1 0.6250 80.0000
CL-40 CHM-1 CTRP1 0.1250 16.0000
CL-40 CI-976 CTRP1 2.0833 266.6700
CL-40 ciclosporin CTRP1 0.2604 33.3330
CL-40 CID 2853753 CTRP1 0.2604 33.3330
CL-40 CIL41 CTRP1 1.2500 160.0000
CL-40 CIL55 CTRP1 0.0781 10.0000
CL-40 CIL55A CTRP1 0.6250 80.0000
CL-40 CIL56 CTRP1 0.0195 2.5000
CL-40 CIL70 CTRP1 0.3125 40.0000
CL-40 Compound 10b CTRP1 1.1562 148.0000
CL-40 Compound 110 CTRP1 0.5781 74.0000
CL-40 Compound 11e CTRP1 0.0130 1.6667
CL-40 Compound 12 CTRP1 0.2891 37.0000
CL-40 Compound 1541A CTRP1 0.2891 37.0000
CL-40 Compound 23 citrate CTRP1 0.2604 33.3330
CL-40 Compound 4 CTRP1 0.2604 33.3330
CL-40 Compound 44 CTRP1 1.0417 133.3300
CL-40 Compound 7d-cis CTRP1 0.2604 33.3330
CL-40 CR-1-31B CTRP1 0.2604 33.3330
CL-40 curcumin CTRP1 1.2500 160.0000
CL-40 cyanoquinoline 11 CTRP1 1.0417 133.3300
CL-40 CYT-997 CTRP1 0.0260 3.3333
CL-40 cytochalasin B CTRP1 0.2604 33.3330
CL-40 cytosporone B CTRP1 0.2604 33.3330
CL-40 Dactolisib CTRP1 0.0163 2.0833
CL-40 dalcetrapib CTRP1 2.0687 264.8000
CL-40 Daporinad CTRP1 0.0020 0.2600
CL-40 darinaparsin CTRP1 0.2604 33.3330
CL-40 DC-45-A2 CTRP1 0.2891 37.0000
CL-40 dexamethasone CTRP1 0.2604 33.3330
CL-40 DG-041 CTRP1 1.0417 133.3300
CL-40 DL-TBOA CTRP1 4.1667 533.3300
CL-40 ELCPK CTRP1 0.0031 0.4000
CL-40 endo-IWR-1 CTRP1 0.2604 33.3330
CL-40 erastin CTRP1 0.1250 16.0000
CL-40 erastin-A8 CTRP1 0.1250 16.0000
CL-40 etomoxir CTRP1 2.3125 296.0000
CL-40 Etoposide CTRP1 0.2212 28.3180
CL-40 fatostatin CTRP1 0.2604 33.3330
CL-40 Fedratinib CTRP1 0.2891 37.0000
CL-40 FGIN-1-27 CTRP1 0.2604 33.3330
CL-40 fluoropyruvate CTRP1 1.1562 148.0000
CL-40 Flutamide CTRP1 0.7542 96.5330
CL-40 FQI-1 CTRP1 0.2604 33.3330
CL-40 FQI-2 CTRP1 0.2604 33.3330
CL-40 fumagillol CTRP1 4.1667 533.3300
CL-40 fumonisin B1 CTRP1 3.9373 504.0000
CL-40 GANT-58 CTRP1 0.2604 33.3330
CL-40 Gemcitabine CTRP1 0.0020 0.2600
CL-40 glibenclamide CTRP1 0.2604 33.3330
CL-40 Gly-Gly-PALO CTRP1 2.0833 266.6700
CL-40 GMX-1778 CTRP1 0.0020 0.2600
CL-40 gossypol CTRP1 0.2891 37.0000
CL-40 GSK-2334470 CTRP1 0.0026 0.3333
CL-40 GW-405833 CTRP1 1.0417 133.3300
CL-40 GW843682X CTRP1 0.2604 33.3330
CL-40 HLI 373 CTRP1 0.2604 33.3330
CL-40 idarubicin CTRP1 0.0020 0.2600
CL-40 importazole CTRP1 1.5625 200.0000
CL-40 indisulam CTRP1 0.2604 33.3330
CL-40 isoevodiamine CTRP1 0.2604 33.3330
CL-40 isoliquiritigenin CTRP1 0.2604 33.3330
CL-40 ISOX CTRP1 0.2604 33.3330
CL-40 itraconazole CTRP1 0.2604 33.3330
CL-40 JQ1 CTRP1 0.0781 10.0000
CL-40 JZL-184 CTRP1 0.2891 37.0000
CL-40 kahalalide F CTRP1 0.2604 33.3330
CL-40 kinetin riboside CTRP1 0.2604 33.3330
CL-40 Ko-143 CTRP1 1.0417 133.3300
CL-40 KU 0060648 CTRP1 0.2604 33.3330
CL-40 LDN-193189 CTRP1 0.2604 33.3330
CL-40 LE-135 CTRP1 0.5208 66.6670
CL-40 Lenalidomide CTRP1 4.6250 592.0000
CL-40 leucascandrolide A CTRP1 0.0163 2.0833
CL-40 LFM-A13 CTRP1 2.8935 370.3700
CL-40 Linsitinib CTRP1 0.2604 33.3330
CL-40 lonidamine CTRP1 4.6250 592.0000
CL-40 losartan CTRP1 4.1667 533.3300
CL-40 lovastatin acid CTRP1 1.0417 133.3300
CL-40 LY-2183240 CTRP1 0.2604 33.3330
CL-40 m-3M3-FBS CTRP1 2.0833 266.6700
CL-40 manumycin A CTRP1 0.2365 30.2680
CL-40 maraviroc CTRP1 0.2604 33.3330
CL-40 MDV-3100 CTRP1 0.0065 0.8333
CL-40 Merck60 CTRP1 0.2604 33.3330
CL-40 minoxidil CTRP1 0.2604 33.3330
CL-40 MK-1775 CTRP1 0.2604 33.3330
CL-40 MK-2206 CTRP1 0.2604 33.3330
CL-40 MK-591 CTRP1 2.0833 266.6700
CL-40 ML006 CTRP1 4.1667 533.3300
CL-40 ML007 CTRP1 0.2891 37.0000
CL-40 ML013 CTRP1 0.5208 66.6670
CL-40 ML030 CTRP1 0.0090 1.1533
CL-40 ML050 CTRP1 0.5208 66.6670
CL-40 ML100 CTRP1 0.2604 33.3330
CL-40 ML101 CTRP1 2.0833 266.6700
CL-40 ML150 CTRP1 0.2604 33.3330
CL-40 ML159 CTRP1 1.0417 133.3300
CL-40 ML160 CTRP1 1.0417 133.3300
CL-40 ML162 CTRP1 0.2604 33.3330
CL-40 ML203 CTRP1 2.3125 296.0000
CL-40 ML210 CTRP1 0.2604 33.3330
CL-40 ML214 CTRP1 0.2604 33.3330
CL-40 MLN2238 CTRP1 0.2604 33.3330
CL-40 MPEP CTRP1 0.2604 33.3330
CL-40 myriocin CTRP1 0.2604 33.3330
CL-40 N-oxalyl-D-phenylalanine CTRP1 4.1667 533.3300
CL-40 N9-isopropylolomoucine CTRP1 3.1914 408.5000
CL-40 nakiterpiosin CTRP1 0.2604 33.3330
CL-40 narciclasine CTRP1 0.2604 33.3330
CL-40 Navitoclax CTRP1 0.2604 33.3330
CL-40 necrostatin-1 CTRP1 4.1667 533.3300
CL-40 neopeltolide CTRP1 0.0000 1.1533
CL-40 neratinib CTRP1 0.2604 33.3330
CL-40 nifedipine CTRP1 0.2604 33.3330
CL-40 nimodipine CTRP1 0.2604 33.3330
CL-40 NPC-26 CTRP1 0.3125 40.0000
CL-40 NSC 74859 CTRP1 4.1667 533.3300
CL-40 NSC23766 CTRP1 4.1667 533.3300
CL-40 NSC632839 CTRP1 0.2604 33.3330
CL-40 NSC95397 CTRP1 0.2604 33.3330
CL-40 NU 1025 CTRP1 0.2604 33.3330
CL-40 Nutlin-3a CTRP1 1.1562 148.0000
CL-40 NVP-AUY922 CTRP1 0.0001 33.3330
CL-40 Olaparib CTRP1 1.1562 148.0000
CL-40 oligomycin A CTRP1 0.2604 33.3330
CL-40 orteronel CTRP1 1.0417 133.3300
CL-40 OSW-1 CTRP1 0.0010 16.6670
CL-40 P-0850 CTRP1 0.2604 33.3330
CL-40 PAC-1 CTRP1 0.2604 33.3330
CL-40 panduratin A CTRP1 2.0833 266.6700
CL-40 parbendazole CTRP1 0.0081 66.6670
CL-40 Parthenolide CTRP1 0.5208 66.6670
CL-40 PDMP CTRP1 1.6667 213.3300
CL-40 Pemetrexed CTRP1 2.3125 296.0000
CL-40 penfluridol CTRP1 0.7813 100.0000
CL-40 Pevonedistat CTRP1 0.2891 37.0000
CL-40 PF-04217903 CTRP1 1.0417 133.3300
CL-40 PF-3845 CTRP1 0.2604 33.3330
CL-40 PF-750 CTRP1 2.0833 266.6700
CL-40 phloretin CTRP1 4.6250 592.0000
CL-40 PI-103 CTRP1 0.2891 37.0000
CL-40 pifithrin-alpha CTRP1 1.8185 232.7700
CL-40 pifithrin-mu CTRP1 0.2604 33.3330
CL-40 PIK-75 CTRP1 0.0023 0.2890
CL-40 Piperlongumine CTRP1 0.2604 35.6930
CL-40 PJ 34 CTRP1 0.2604 33.3330
CL-40 PK-11195 CTRP1 4.1667 533.3300
CL-40 PNU-74654 CTRP1 2.0833 266.6700
CL-40 PP-30 CTRP1 0.2891 37.0000
CL-40 PRIMA-1 CTRP1 1.1562 148.0000
CL-40 PRIMA-1MET CTRP1 0.2604 33.3330
CL-40 PRL-3 Inhibitor I CTRP1 1.0417 133.3300
CL-40 PT-630 CTRP1 0.2604 33.3330
CL-40 purmorphamine CTRP1 1.1562 148.0000
CL-40 PX-12 CTRP1 0.7813 100.0000
CL-40 pyrvinium pamoate CTRP1 0.2604 33.3330
CL-40 QS11 CTRP1 0.2604 33.3330
CL-40 quinoclamine CTRP1 0.2891 37.0000
CL-40 Rapamycin CTRP1 0.2891 37.0000
CL-40 RG-108 CTRP1 2.0833 266.6700
CL-40 RITA CTRP1 0.2604 33.3330
CL-40 Ro-28-1675 CTRP1 4.1667 533.3300
CL-40 rosiglitazone CTRP1 2.0833 266.6700
CL-40 rotenone CTRP1 0.0163 2.0833
CL-40 RS-23597-190 CTRP1 4.1667 533.3300
CL-40 Rucaparib CTRP1 0.2604 33.3330
CL-40 salermide CTRP1 3.1250 400.0000
CL-40 SB-225002 CTRP1 0.2891 37.0000
CL-40 SCH-529074 CTRP1 0.2604 33.3330
CL-40 SCH-79797 CTRP1 0.2891 37.0000
CL-40 Selisistat CTRP1 0.6250 80.0000
CL-40 Selumetinib CTRP1 2.0833 266.6700
CL-40 Sepantronium bromide CTRP1 0.0081 1.0417
CL-40 Serdemetan CTRP1 0.2604 33.3330
CL-40 SID 26681509 CTRP1 2.3125 296.0000
CL-40 sildenafil CTRP1 4.1667 533.3300
CL-40 simvastatin CTRP1 0.2604 33.3330
CL-40 SJ-172550 CTRP1 0.2891 37.0000
CL-40 SKI-II CTRP1 1.0417 133.3300
CL-40 SN-38 CTRP1 0.0090 1.1533
CL-40 SNX-2112 CTRP1 0.0020 0.2600
CL-40 sparfosic acid CTRP1 2.0833 266.6700
CL-40 SR-II-138A CTRP1 0.0020 0.2600
CL-40 T-5345967 CTRP1 4.1667 533.3300
CL-40 tacrolimus CTRP1 0.5781 74.0000
CL-40 tamatinib CTRP1 0.2604 33.3330
CL-40 Tamoxifen CTRP1 0.7393 94.6330
CL-40 Tanespimycin CTRP1 0.0090 1.1533
CL-40 Telomerase Inhibitor IX CTRP1 0.2891 37.0000
CL-40 Teniposide CTRP1 0.0326 4.1667
CL-40 TGX-115 CTRP1 4.1667 533.3300
CL-40 tipifarnib-P1 CTRP1 0.2604 33.3330
CL-40 tipifarnib-P2 CTRP1 0.2604 33.3330
CL-40 Tivozanib CTRP1 0.2604 33.3330
CL-40 tosedostat CTRP1 2.0833 266.6700
CL-40 Tozasertib CTRP1 0.2604 33.3330
CL-40 Tretinoin CTRP1 1.0417 133.3300
CL-40 triacsin C CTRP1 0.2604 33.3330
CL-40 trifluoperazine CTRP1 0.2604 33.3330
CL-40 triptolide CTRP1 0.0020 0.2600
CL-40 TTNBP CTRP1 0.0260 3.3333
CL-40 Tubastatin A CTRP1 0.2604 33.3330
CL-40 TW 37 CTRP1 0.2604 33.3330
CL-40 tyrphostin AG-1478 CTRP1 1.4787 189.2800
CL-40 ubistatin B CTRP1 4.1667 533.3300
CL-40 UK 356618 CTRP1 0.2604 33.3330
CL-40 UNC0321 CTRP1 0.2604 33.3330
CL-40 UNC0638 CTRP1 0.2604 33.3330
CL-40 ursolic acid CTRP1 1.8247 233.5600
CL-40 valdecoxib CTRP1 4.6250 592.0000
CL-40 Veliparib CTRP1 0.2604 33.3330
CL-40 VER-155008 CTRP1 0.2891 37.0000
CL-40 Vismodegib CTRP1 0.2604 33.3330
CL-40 Vorinostat CTRP1 0.2891 37.0000
CL-40 WT-161 CTRP1 0.2604 33.3330
CL-40 XAV939 CTRP1 0.2891 37.0000
CL-40 YK-4-279 CTRP1 0.2604 33.3330
CL-40 zebularine CTRP1 4.6250 592.0000
CL-40 zileuton CTRP1 4.1667 533.3300
CL-40 ZM336372 CTRP1 2.6747 342.3700

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC