Drug : 10-Debc

CTRP1 Name : 10-DEBC

Dataset : All
Synonyms :
Targets : AKT
Pathways : inhibitor of AKT

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
10-DEBC MCF-7 CTRP1 0.6250 80.0000
10-DEBC LN-229 CTRP1 0.6250 80.0000
10-DEBC JHUEM-2 CTRP1 0.6250 80.0000
10-DEBC EJM CTRP1 0.6250 80.0000
10-DEBC GDM-1 CTRP1 0.6250 80.0000
10-DEBC MOLM-16 CTRP1 0.6250 80.0000
10-DEBC NOMO-1 CTRP1 0.6250 80.0000
10-DEBC NU-DUL-1 CTRP1 0.6250 80.0000
10-DEBC OCI-AML-3 CTRP1 0.6250 80.0000
10-DEBC PL21 CTRP1 0.6250 80.0000
10-DEBC RPMI-8226 CTRP1 0.6250 80.0000
10-DEBC SKM-1 CTRP1 0.6250 80.0000
10-DEBC SU-DHL-4 CTRP1 0.6250 80.0000
10-DEBC SU-DHL-5 CTRP1 0.6250 80.0000
10-DEBC THP-1 CTRP1 0.6250 80.0000
10-DEBC U-937 CTRP1 0.6250 80.0000
10-DEBC WSU-DLCL2 CTRP1 0.6250 80.0000
10-DEBC CL-34 CTRP1 0.6250 80.0000
10-DEBC CL-40 CTRP1 0.6250 80.0000
10-DEBC COLO320 CTRP1 0.6250 80.0000
10-DEBC COLO678 CTRP1 0.6250 80.0000
10-DEBC CW-2 CTRP1 0.6250 80.0000
10-DEBC HCT116 CTRP1 0.6250 80.0000
10-DEBC HCT8 CTRP1 0.6250 80.0000
10-DEBC HT115 CTRP1 0.6250 80.0000
10-DEBC HT-29 CTRP1 0.6250 80.0000
10-DEBC HT-55 CTRP1 0.6250 80.0000
10-DEBC KM12 CTRP1 0.6250 80.0000
10-DEBC LOVO CTRP1 0.6250 80.0000
10-DEBC LS123 CTRP1 0.6250 80.0000
10-DEBC MDST8 CTRP1 0.6250 80.0000
10-DEBC NCI-H508 CTRP1 0.6250 80.0000
10-DEBC RCM-1[HUMANESC] CTRP1 0.6250 80.0000
10-DEBC RKO CTRP1 0.6250 80.0000
10-DEBC SNU-1040 CTRP1 0.6250 80.0000
10-DEBC SNU-175 CTRP1 0.6250 80.0000
10-DEBC SNU-61 CTRP1 0.6250 80.0000
10-DEBC SNU-81 CTRP1 0.6250 80.0000
10-DEBC SNU-C4 CTRP1 0.6250 80.0000
10-DEBC SNU-C5 CTRP1 0.6250 80.0000
10-DEBC SW480 CTRP1 0.6250 80.0000
10-DEBC SW620 CTRP1 0.6250 80.0000
10-DEBC SW948 CTRP1 0.6250 80.0000
10-DEBC HEP-G2 CTRP1 0.6250 80.0000
10-DEBC CAL-12T CTRP1 0.6250 80.0000
10-DEBC COLO699 CTRP1 0.6250 80.0000
10-DEBC COR-L23 CTRP1 0.6250 80.0000
10-DEBC HCC1195 CTRP1 0.6250 80.0000
10-DEBC HCC1359 CTRP1 0.6250 80.0000
10-DEBC HCC15 CTRP1 0.6250 80.0000
10-DEBC HCC1833 CTRP1 0.6250 80.0000
10-DEBC HCC2108 CTRP1 0.6250 80.0000
10-DEBC HCC2935 CTRP1 0.6250 80.0000
10-DEBC HCC4006 CTRP1 0.6250 80.0000
10-DEBC HCC827 CTRP1 0.6250 80.0000
10-DEBC NCI-H1105 CTRP1 0.6250 80.0000
10-DEBC NCI-H1694 CTRP1 0.6250 80.0000
10-DEBC NCI-H1755 CTRP1 0.6250 80.0000
10-DEBC NCI-H1781 CTRP1 0.6250 80.0000
10-DEBC NCI-H1836 CTRP1 0.6250 80.0000
10-DEBC NCI-H1876 CTRP1 0.6250 80.0000
10-DEBC NCI-H2023 CTRP1 0.6250 80.0000
10-DEBC NCI-H2030 CTRP1 0.6250 80.0000
10-DEBC NCI-H2073 CTRP1 0.6250 80.0000
10-DEBC NCI-H2081 CTRP1 0.6250 80.0000
10-DEBC NCI-H2110 CTRP1 0.6250 80.0000
10-DEBC NCI-H2122 CTRP1 0.6250 80.0000
10-DEBC NCI-H2172 CTRP1 0.6250 80.0000
10-DEBC NCI-H2342 CTRP1 0.6250 80.0000
10-DEBC NCI-H3255 CTRP1 0.6250 80.0000
10-DEBC NCI-H441 CTRP1 0.6250 80.0000
10-DEBC NCI-H460 CTRP1 0.6250 80.0000
10-DEBC NCI-H596 CTRP1 0.6250 80.0000
10-DEBC NCI-H841 CTRP1 0.6250 80.0000
10-DEBC SK-LU-1 CTRP1 0.6250 80.0000
10-DEBC SQ-1 CTRP1 0.6250 80.0000
10-DEBC T3M-10 CTRP1 0.6250 80.0000
10-DEBC CAOV-3 CTRP1 0.6250 80.0000
10-DEBC COV362 CTRP1 0.6250 80.0000
10-DEBC COV434 CTRP1 0.6250 80.0000
10-DEBC COV644 CTRP1 0.6250 80.0000
10-DEBC EFO-27 CTRP1 0.6250 80.0000
10-DEBC JHOC-5 CTRP1 0.6250 80.0000
10-DEBC JHOM-1 CTRP1 0.6250 80.0000
10-DEBC OAW42 CTRP1 0.6250 80.0000
10-DEBC OV7 CTRP1 0.6250 80.0000
10-DEBC OV-90 CTRP1 0.6250 80.0000
10-DEBC OVK18 CTRP1 0.6250 80.0000
10-DEBC RMG-I CTRP1 0.6250 80.0000
10-DEBC RMUG-S CTRP1 0.6250 80.0000
10-DEBC SNU-840 CTRP1 0.6250 80.0000
10-DEBC TYK-NU CTRP1 0.6250 80.0000
10-DEBC A-375 CTRP1 0.6250 80.0000
10-DEBC SK-MEL-1 CTRP1 0.6250 80.0000
10-DEBC SK-MEL-28 CTRP1 0.6250 80.0000
10-DEBC SK-MEL-5 CTRP1 0.6250 80.0000
10-DEBC HT-1080 CTRP1 0.6250 80.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.