Drug : Nimodipine

CTRP1 Name : nimodipine

Dataset : All
Synonyms :
Targets : CACNA1C;CACNA1D;CACNA1S;CACNA1F
Pathways : inhibitor of L-type calcium channel

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
nimodipine MCF-7 CTRP1 0.2604 33.3330
nimodipine LN-229 CTRP1 0.2604 33.3330
nimodipine JHUEM-2 CTRP1 0.2604 33.3330
nimodipine EJM CTRP1 0.2604 33.3330
nimodipine GDM-1 CTRP1 0.2604 33.3330
nimodipine MOLM-16 CTRP1 0.2604 33.3330
nimodipine NOMO-1 CTRP1 0.2604 33.3330
nimodipine NU-DUL-1 CTRP1 0.2604 33.3330
nimodipine OCI-AML-3 CTRP1 0.2604 33.3330
nimodipine PL21 CTRP1 0.2604 33.3330
nimodipine RPMI-8226 CTRP1 0.2604 33.3330
nimodipine SKM-1 CTRP1 0.2604 33.3330
nimodipine SU-DHL-4 CTRP1 0.2604 33.3330
nimodipine SU-DHL-5 CTRP1 0.2604 33.3330
nimodipine THP-1 CTRP1 0.2604 33.3330
nimodipine U-937 CTRP1 0.2604 33.3330
nimodipine WSU-DLCL2 CTRP1 0.2604 33.3330
nimodipine CL-34 CTRP1 0.2604 33.3330
nimodipine CL-40 CTRP1 0.2604 33.3330
nimodipine COLO320 CTRP1 0.2604 33.3330
nimodipine COLO678 CTRP1 0.2604 33.3330
nimodipine CW-2 CTRP1 0.2604 33.3330
nimodipine HCT116 CTRP1 0.2604 33.3330
nimodipine HCT8 CTRP1 0.2604 33.3330
nimodipine HT115 CTRP1 0.2604 33.3330
nimodipine HT-29 CTRP1 0.2604 33.3330
nimodipine HT-55 CTRP1 0.2604 33.3330
nimodipine KM12 CTRP1 0.2604 33.3330
nimodipine LOVO CTRP1 0.2604 33.3330
nimodipine LS123 CTRP1 0.2604 33.3330
nimodipine MDST8 CTRP1 0.2604 33.3330
nimodipine NCI-H508 CTRP1 0.2604 33.3330
nimodipine RCM-1[HUMANESC] CTRP1 0.2604 33.3330
nimodipine RKO CTRP1 0.2604 33.3330
nimodipine SNU-1040 CTRP1 0.2604 33.3330
nimodipine SNU-175 CTRP1 0.2604 33.3330
nimodipine SNU-61 CTRP1 0.2604 33.3330
nimodipine SNU-81 CTRP1 0.2604 33.3330
nimodipine SNU-C4 CTRP1 0.2604 33.3330
nimodipine SNU-C5 CTRP1 0.2604 33.3330
nimodipine SW480 CTRP1 0.2604 33.3330
nimodipine SW620 CTRP1 0.2604 33.3330
nimodipine SW948 CTRP1 0.2604 33.3330
nimodipine HEP-G2 CTRP1 0.2604 33.3330
nimodipine CAL-12T CTRP1 0.2604 33.3330
nimodipine COLO699 CTRP1 0.2604 33.3330
nimodipine COR-L23 CTRP1 0.2604 33.3330
nimodipine HCC1195 CTRP1 0.2604 33.3330
nimodipine HCC1359 CTRP1 0.2604 33.3330
nimodipine HCC15 CTRP1 0.2604 33.3330
nimodipine HCC1833 CTRP1 0.2604 33.3330
nimodipine HCC2108 CTRP1 0.2604 33.3330
nimodipine HCC2935 CTRP1 0.2604 33.3330
nimodipine HCC4006 CTRP1 0.2604 33.3330
nimodipine HCC827 CTRP1 0.2604 33.3330
nimodipine NCI-H1105 CTRP1 0.2604 33.3330
nimodipine NCI-H1694 CTRP1 0.2604 33.3330
nimodipine NCI-H1755 CTRP1 0.2604 33.3330
nimodipine NCI-H1781 CTRP1 0.2604 33.3330
nimodipine NCI-H1836 CTRP1 0.2604 33.3330
nimodipine NCI-H1876 CTRP1 0.2604 33.3330
nimodipine NCI-H2023 CTRP1 0.2604 33.3330
nimodipine NCI-H2030 CTRP1 0.2604 33.3330
nimodipine NCI-H2073 CTRP1 0.2604 33.3330
nimodipine NCI-H2081 CTRP1 0.2604 33.3330
nimodipine NCI-H2110 CTRP1 0.2604 33.3330
nimodipine NCI-H2122 CTRP1 0.2604 33.3330
nimodipine NCI-H2172 CTRP1 0.2604 33.3330
nimodipine NCI-H2342 CTRP1 0.2604 33.3330
nimodipine NCI-H3255 CTRP1 0.2604 33.3330
nimodipine NCI-H441 CTRP1 0.2604 33.3330
nimodipine NCI-H460 CTRP1 0.2604 33.3330
nimodipine NCI-H596 CTRP1 0.2604 33.3330
nimodipine NCI-H841 CTRP1 0.2604 33.3330
nimodipine SK-LU-1 CTRP1 0.2604 33.3330
nimodipine SQ-1 CTRP1 0.2604 33.3330
nimodipine T3M-10 CTRP1 0.2604 33.3330
nimodipine CAOV-3 CTRP1 0.2604 33.3330
nimodipine COV362 CTRP1 0.2604 33.3330
nimodipine COV434 CTRP1 0.2604 33.3330
nimodipine COV644 CTRP1 0.2604 33.3330
nimodipine EFO-27 CTRP1 0.2604 33.3330
nimodipine JHOC-5 CTRP1 0.2604 33.3330
nimodipine JHOM-1 CTRP1 0.2604 33.3330
nimodipine OAW42 CTRP1 0.2604 33.3330
nimodipine OV7 CTRP1 0.2604 33.3330
nimodipine OV-90 CTRP1 0.2604 33.3330
nimodipine OVK18 CTRP1 0.2604 33.3330
nimodipine RMG-I CTRP1 0.2604 33.3330
nimodipine RMUG-S CTRP1 0.2604 33.3330
nimodipine SNU-840 CTRP1 0.2604 33.3330
nimodipine TYK-NU CTRP1 0.2604 33.3330
nimodipine A-375 CTRP1 0.2604 33.3330
nimodipine SK-MEL-1 CTRP1 0.2604 33.3330
nimodipine SK-MEL-28 CTRP1 0.2604 33.3330
nimodipine SK-MEL-5 CTRP1 0.2604 33.3330
nimodipine HT-1080 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.