Drug : Rotenone

CTRP1 Name : rotenone

Dataset : All
Synonyms :
Targets :
Pathways : inhibitor of mitochondrial electron transport chain at complex I

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
rotenone U2OS CTRP1 0.0163 2.0833
rotenone MCF-7 CTRP1 0.0163 2.0833
rotenone GAMG CTRP1 0.2603 33.3330
rotenone LN-229 CTRP1 0.0163 2.0833
rotenone SF295 CTRP1 0.2603 33.3330
rotenone HEC-108 CTRP1 0.2603 33.3330
rotenone HEC-151 CTRP1 0.0163 2.0833
rotenone HEC-251 CTRP1 0.2603 33.3330
rotenone HEC-265 CTRP1 0.2603 33.3330
rotenone HEC-59 CTRP1 0.2603 33.3330
rotenone HEC-6 CTRP1 0.2603 33.3330
rotenone ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
rotenone JHUEM-2 CTRP1 0.0163 2.0833
rotenone KLE CTRP1 0.2603 33.3330
rotenone MFE-319 CTRP1 0.2603 33.3330
rotenone SNG-M CTRP1 0.2603 33.3330
rotenone AMO1 CTRP1 0.0163 2.0833
rotenone BL-70 CTRP1 0.2603 33.3330
rotenone EJM CTRP1 0.0163 2.0833
rotenone GDM-1 CTRP1 0.0163 2.0833
rotenone HT CTRP1 0.2603 33.3330
rotenone KMS-11 CTRP1 0.0163 2.0833
rotenone KU812 CTRP1 0.2603 33.3330
rotenone LP-1 CTRP1 0.0163 2.0833
rotenone MC116 CTRP1 0.2603 33.3330
rotenone MOLM-16 CTRP1 0.0163 2.0833
rotenone NOMO-1 CTRP1 0.0163 2.0833
rotenone NU-DUL-1 CTRP1 0.0163 2.0833
rotenone OCI-AML-3 CTRP1 0.0163 2.0833
rotenone OCI-LY10 CTRP1 0.0163 2.0833
rotenone P3HR-1 CTRP1 0.2603 33.3330
rotenone PL21 CTRP1 0.0163 2.0833
rotenone RPMI-8226 CTRP1 0.0163 2.0833
rotenone SKM-1 CTRP1 0.0163 2.0833
rotenone SU-DHL-4 CTRP1 0.0163 2.0833
rotenone SU-DHL-5 CTRP1 0.0163 2.0833
rotenone THP-1 CTRP1 0.0163 2.0833
rotenone U-937 CTRP1 0.0163 2.0833
rotenone WSU-DLCL2 CTRP1 0.0163 2.0833
rotenone RCC10RGB CTRP1 0.0163 2.0833
rotenone VMRC-RCW CTRP1 0.2603 33.3330
rotenone C2BBE1 CTRP1 0.2603 33.3330
rotenone CL-34 CTRP1 0.0163 2.0833
rotenone CL-40 CTRP1 0.0163 2.0833
rotenone COLO205 CTRP1 0.2603 33.3330
rotenone COLO320 CTRP1 0.0163 1.0417
rotenone COLO678 CTRP1 0.0163 2.0833
rotenone CW-2 CTRP1 0.0163 2.0833
rotenone DLD-1 CTRP1 0.2603 33.3330
rotenone GP2D CTRP1 0.2603 33.3330
rotenone HCT116 CTRP1 0.0163 2.0833
rotenone HCT8 CTRP1 0.0163 2.0833
rotenone HT115 CTRP1 0.0163 2.0833
rotenone HT-29 CTRP1 0.0163 2.0833
rotenone HT-55 CTRP1 0.0163 2.0833
rotenone KM12 CTRP1 0.0163 2.0833
rotenone LOVO CTRP1 0.0163 2.0833
rotenone LS123 CTRP1 0.0163 2.0833
rotenone LS180 CTRP1 0.0163 2.0833
rotenone LS411N CTRP1 0.2603 33.3330
rotenone LS513 CTRP1 0.2603 33.3330
rotenone MDST8 CTRP1 0.0163 2.0833
rotenone NCI-H508 CTRP1 0.0163 2.0833
rotenone RCM-1[HUMANESC] CTRP1 0.0163 2.0833
rotenone RKO CTRP1 0.0163 2.0833
rotenone SK-CO-1 CTRP1 0.2603 33.3330
rotenone SNU-1040 CTRP1 0.0163 2.0833
rotenone SNU-175 CTRP1 0.0163 2.0833
rotenone SNU-61 CTRP1 0.0163 2.0833
rotenone SNU-81 CTRP1 0.0163 2.0833
rotenone SNU-C2A CTRP1 0.2603 33.3330
rotenone SNU-C4 CTRP1 0.0163 2.0833
rotenone SNU-C5 CTRP1 0.0163 2.0833
rotenone SW403 CTRP1 0.2603 33.3330
rotenone SW48 CTRP1 0.2603 33.3330
rotenone SW480 CTRP1 0.0163 2.0833
rotenone SW620 CTRP1 0.0163 2.0833
rotenone SW948 CTRP1 0.0163 2.0833
rotenone HEP-G2 CTRP1 0.0163 2.0833
rotenone JHH-6 CTRP1 0.2603 33.3330
rotenone SNU-398 CTRP1 0.0163 2.0833
rotenone SNU-449 CTRP1 0.2603 33.3330
rotenone A-549 CTRP1 0.2603 33.3330
rotenone BEN CTRP1 0.2603 33.3330
rotenone CAL-12T CTRP1 0.0163 2.0833
rotenone CALU-3 CTRP1 0.2603 33.3330
rotenone CALU-6 CTRP1 0.2603 33.3330
rotenone CHAGO-K-1 CTRP1 0.2603 33.3330
rotenone COLO668 CTRP1 0.2603 33.3330
rotenone COLO699 CTRP1 0.0163 2.0833
rotenone COR-L23 CTRP1 0.0163 2.0833
rotenone COR-L279 CTRP1 0.2603 33.3330
rotenone COR-L51 CTRP1 0.0163 2.0833
rotenone COR-L88 CTRP1 0.2603 33.3330
rotenone DMS273 CTRP1 0.2603 33.3330
rotenone DV-90 CTRP1 0.2603 33.3330
rotenone EBC-1 CTRP1 0.2603 33.3330
rotenone EPLC-272H CTRP1 0.2603 33.3330
rotenone HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
rotenone HCC1195 CTRP1 0.0163 2.0833
rotenone HCC1359 CTRP1 0.0163 2.0833
rotenone HCC15 CTRP1 0.0163 2.0833
rotenone HCC1833 CTRP1 0.0163 2.0833
rotenone HCC2108 CTRP1 0.0163 2.0833
rotenone HCC2935 CTRP1 0.0163 2.0833
rotenone HCC33 CTRP1 0.2603 33.3330
rotenone HCC4006 CTRP1 0.0163 2.0833
rotenone HCC44 CTRP1 0.2603 33.3330
rotenone HCC78 CTRP1 0.2603 33.3330
rotenone HCC827 CTRP1 0.0163 2.0833
rotenone KNS-62 CTRP1 0.2603 33.3330
rotenone LC-1-SQ-SF CTRP1 0.2603 33.3330
rotenone LCLC-103H CTRP1 0.2603 33.3330
rotenone LCLC-97TM1 CTRP1 0.2603 33.3330
rotenone LU-65 CTRP1 0.2603 33.3330
rotenone LU-99 CTRP1 0.2603 33.3330
rotenone LXF289 CTRP1 0.2603 33.3330
rotenone NCI-H1048 CTRP1 0.2603 33.3330
rotenone NCI-H1105 CTRP1 0.0163 2.0833
rotenone NCI-H1299 CTRP1 0.2603 33.3330
rotenone NCI-H1355 CTRP1 0.2603 33.3330
rotenone NCI-H1373 CTRP1 0.2603 33.3330
rotenone NCI-H1435 CTRP1 0.2603 33.3330
rotenone NCI-H1437 CTRP1 0.2603 33.3330
rotenone NCI-H1568 CTRP1 0.2603 33.3330
rotenone NCI-H1573 CTRP1 0.2603 33.3330
rotenone NCI-H1666 CTRP1 0.2603 33.3330
rotenone NCI-H1694 CTRP1 0.0163 2.0833
rotenone NCI-H1755 CTRP1 0.0163 2.0833
rotenone NCI-H1781 CTRP1 0.0163 2.0833
rotenone NCI-H1792 CTRP1 0.2603 33.3330
rotenone NCI-H1793 CTRP1 0.2603 33.3330
rotenone NCI-H1836 CTRP1 0.0163 2.0833
rotenone NCI-H1876 CTRP1 0.0163 2.0833
rotenone NCI-H1915 CTRP1 0.2603 33.3330
rotenone NCI-H1930 CTRP1 0.2603 33.3330
rotenone NCI-H1944 CTRP1 0.2603 33.3330
rotenone NCI-H1963 CTRP1 0.0163 2.0833
rotenone NCI-H1975 CTRP1 0.2603 33.3330
rotenone NCI-H2009 CTRP1 0.0163 33.3330
rotenone NCI-H2023 CTRP1 0.0163 2.0833
rotenone NCI-H2029 CTRP1 0.2603 33.3330
rotenone NCI-H2030 CTRP1 0.0163 2.0833
rotenone NCI-H2073 CTRP1 0.0163 2.0833
rotenone NCI-H2081 CTRP1 0.0163 2.0833
rotenone NCI-H2110 CTRP1 0.0163 2.0833
rotenone NCI-H2122 CTRP1 0.0163 2.0833
rotenone NCI-H2126 CTRP1 0.2603 33.3330
rotenone NCI-H2141 CTRP1 0.0163 2.0833
rotenone NCI-H2172 CTRP1 0.0163 2.0833
rotenone NCI-H2286 CTRP1 0.2603 33.3330
rotenone NCI-H23 CTRP1 0.2603 33.3330
rotenone NCI-H2342 CTRP1 0.0163 2.0833
rotenone NCI-H2405 CTRP1 0.2603 33.3330
rotenone NCI-H3255 CTRP1 0.0163 2.0833
rotenone NCI-H358 CTRP1 0.2603 33.3330
rotenone NCI-H441 CTRP1 0.0163 2.0833
rotenone NCI-H460 CTRP1 0.0163 2.0833
rotenone NCI-H522 CTRP1 0.2603 33.3330
rotenone NCI-H596 CTRP1 0.0163 2.0833
rotenone NCI-H650 CTRP1 0.2603 33.3330
rotenone NCI-H661 CTRP1 0.2603 33.3330
rotenone NCI-H727 CTRP1 0.2603 33.3330
rotenone NCI-H810 CTRP1 0.2603 33.3330
rotenone NCI-H82 CTRP1 0.2603 33.3330
rotenone NCI-H841 CTRP1 0.0163 2.0833
rotenone RERF-LC-KJ CTRP1 0.2603 33.3330
rotenone SCLC-21H CTRP1 0.0163 2.0833
rotenone SHP-77 CTRP1 0.2603 33.3330
rotenone SK-LU-1 CTRP1 0.0163 2.0833
rotenone SQ-1 CTRP1 0.0163 2.0833
rotenone T3M-10 CTRP1 0.0163 2.0833
rotenone VMRC-LCD CTRP1 0.2603 33.3330
rotenone KYSE-140 CTRP1 0.2603 33.3330
rotenone KYSE-410 CTRP1 0.2603 33.3330
rotenone KYSE-450 CTRP1 0.2603 33.3330
rotenone A2780 CTRP1 0.0163 2.0833
rotenone CAOV-3 CTRP1 0.0163 2.0833
rotenone COV318 CTRP1 0.2603 33.3330
rotenone COV362 CTRP1 0.0163 2.0833
rotenone COV434 CTRP1 0.0163 2.0833
rotenone COV644 CTRP1 0.0163 2.0833
rotenone EFO-21 CTRP1 0.2603 33.3330
rotenone EFO-27 CTRP1 0.0163 2.0833
rotenone HEYA8 CTRP1 0.2603 33.3330
rotenone IGROV-1 CTRP1 0.0163 2.0833
rotenone JHOC-5 CTRP1 0.0163 2.0833
rotenone JHOM-1 CTRP1 0.0163 2.0833
rotenone JHOS-4 CTRP1 0.2603 33.3330
rotenone OAW42 CTRP1 0.0163 2.0833
rotenone OV7 CTRP1 0.0163 2.0833
rotenone OV-90 CTRP1 0.0163 2.0833
rotenone OVCAR-4 CTRP1 0.0163 2.0833
rotenone OVCAR-8 CTRP1 0.0163 2.0833
rotenone OVK18 CTRP1 0.0163 2.0833
rotenone OVKATE CTRP1 0.0163 2.0833
rotenone OVMANA CTRP1 0.2603 33.3330
rotenone RKN CTRP1 0.0163 2.0833
rotenone RMG-I CTRP1 0.0163 2.0833
rotenone RMUG-S CTRP1 0.0163 2.0833
rotenone SK-OV-3 CTRP1 0.2603 33.3330
rotenone SNU-840 CTRP1 0.0163 2.0833
rotenone TYK-NU CTRP1 0.0163 2.0833
rotenone CAPAN-2 CTRP1 0.2603 33.3330
rotenone CFPAC-1 CTRP1 0.2603 33.3330
rotenone HPAC CTRP1 0.2603 33.3330
rotenone HUP-T4 CTRP1 0.2603 33.3330
rotenone KP-3 CTRP1 0.2603 33.3330
rotenone PANC03.27 CTRP1 0.2603 33.3330
rotenone PANC10.05 CTRP1 0.2603 33.3330
rotenone PATU8902 CTRP1 0.2603 33.3330
rotenone QGP-1 CTRP1 0.2603 33.3330
rotenone SUIT-2 CTRP1 0.2603 33.3330
rotenone MSTO-211H CTRP1 0.2603 33.3330
rotenone NCI-H2052 CTRP1 0.2603 33.3330
rotenone NCI-H28 CTRP1 0.2603 33.3330
rotenone MIAPACA-3 CTRP1 0.2603 33.3330
rotenone A-375 CTRP1 0.0163 2.0833
rotenone COLO741 CTRP1 0.2603 33.3330
rotenone G-361 CTRP1 0.2603 33.3330
rotenone HS852.T CTRP1 0.2603 33.3330
rotenone HS936.T CTRP1 0.2603 33.3330
rotenone HS944.T CTRP1 0.2603 33.3330
rotenone SK-MEL-1 CTRP1 0.0163 2.0833
rotenone SK-MEL-28 CTRP1 0.0163 2.0833
rotenone SK-MEL-5 CTRP1 0.0163 2.0833
rotenone G-401 CTRP1 0.2603 33.3330
rotenone HT-1080 CTRP1 0.0163 2.0833
rotenone AGS CTRP1 0.0163 2.0833
rotenone FU97 CTRP1 0.2603 33.3330
rotenone KE-97 CTRP1 0.2603 33.3330
rotenone MKN7 CTRP1 0.2603 33.3330
rotenone MKN74 CTRP1 0.2603 33.3330
rotenone NUGC-4 CTRP1 0.2603 33.3330
rotenone SH-10-TC CTRP1 0.2603 33.3330
rotenone HSC-2 CTRP1 0.2603 33.3330
rotenone SCC-9 CTRP1 0.0163 2.0833
rotenone 5637 CTRP1 0.2603 33.3330
rotenone HT-1376 CTRP1 0.2603 33.3330
rotenone KMBC-2 CTRP1 0.2603 33.3330
rotenone RT-4 CTRP1 0.2603 33.3330
rotenone UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.