Drug : Compound 4

CTRP1 Name : Compound 4

Dataset : All
Synonyms :
Targets : PTPN1
Pathways : inhibitor of protein tyrosine phosphatase PTP1B

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
Compound 4 U2OS CTRP1 0.2604 33.3330
Compound 4 MCF-7 CTRP1 0.2604 33.3330
Compound 4 GAMG CTRP1 0.2603 33.3330
Compound 4 LN-229 CTRP1 0.2604 33.3330
Compound 4 SF295 CTRP1 0.2603 33.3330
Compound 4 HEC-108 CTRP1 0.2603 33.3330
Compound 4 HEC-151 CTRP1 0.2604 33.3330
Compound 4 HEC-251 CTRP1 0.2603 33.3330
Compound 4 HEC-265 CTRP1 0.2603 33.3330
Compound 4 HEC-59 CTRP1 0.2603 33.3330
Compound 4 HEC-6 CTRP1 0.2603 33.3330
Compound 4 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
Compound 4 JHUEM-2 CTRP1 0.2604 33.3330
Compound 4 KLE CTRP1 0.2603 33.3330
Compound 4 MFE-319 CTRP1 0.2603 33.3330
Compound 4 SNG-M CTRP1 0.2603 33.3330
Compound 4 AMO1 CTRP1 0.2604 33.3330
Compound 4 BL-70 CTRP1 0.2603 33.3330
Compound 4 EJM CTRP1 0.2604 33.3330
Compound 4 GDM-1 CTRP1 0.2604 33.3330
Compound 4 HT CTRP1 0.2603 33.3330
Compound 4 KMS-11 CTRP1 0.2604 33.3330
Compound 4 KU812 CTRP1 0.2603 33.3330
Compound 4 LP-1 CTRP1 0.2604 33.3330
Compound 4 MC116 CTRP1 0.2603 33.3330
Compound 4 MOLM-16 CTRP1 0.2604 33.3330
Compound 4 NOMO-1 CTRP1 0.2604 33.3330
Compound 4 NU-DUL-1 CTRP1 0.2604 33.3330
Compound 4 OCI-AML-3 CTRP1 0.2604 33.3330
Compound 4 OCI-LY10 CTRP1 0.2604 33.3330
Compound 4 P3HR-1 CTRP1 0.2603 33.3330
Compound 4 PL21 CTRP1 0.2604 33.3330
Compound 4 RPMI-8226 CTRP1 0.2604 33.3330
Compound 4 SKM-1 CTRP1 0.2604 33.3330
Compound 4 SU-DHL-4 CTRP1 0.2604 33.3330
Compound 4 SU-DHL-5 CTRP1 0.2604 33.3330
Compound 4 THP-1 CTRP1 0.2604 33.3330
Compound 4 U-937 CTRP1 0.2604 33.3330
Compound 4 WSU-DLCL2 CTRP1 0.2604 33.3330
Compound 4 RCC10RGB CTRP1 0.2604 33.3330
Compound 4 VMRC-RCW CTRP1 0.2603 33.3330
Compound 4 C2BBE1 CTRP1 0.2603 33.3330
Compound 4 CL-34 CTRP1 0.2604 33.3330
Compound 4 CL-40 CTRP1 0.2604 33.3330
Compound 4 COLO205 CTRP1 0.2603 33.3330
Compound 4 COLO320 CTRP1 0.2604 33.3330
Compound 4 COLO678 CTRP1 0.2604 33.3330
Compound 4 CW-2 CTRP1 0.2604 33.3330
Compound 4 DLD-1 CTRP1 0.2603 33.3330
Compound 4 GP2D CTRP1 0.2603 33.3330
Compound 4 HCT116 CTRP1 0.2604 33.3330
Compound 4 HCT8 CTRP1 0.2604 33.3330
Compound 4 HT115 CTRP1 0.2604 33.3330
Compound 4 HT-29 CTRP1 0.2604 33.3330
Compound 4 HT-55 CTRP1 0.2604 33.3330
Compound 4 KM12 CTRP1 0.2604 33.3330
Compound 4 LOVO CTRP1 0.2604 33.3330
Compound 4 LS123 CTRP1 0.2604 33.3330
Compound 4 LS180 CTRP1 0.2604 33.3330
Compound 4 LS411N CTRP1 0.2603 33.3330
Compound 4 LS513 CTRP1 0.2603 33.3330
Compound 4 MDST8 CTRP1 0.2604 33.3330
Compound 4 NCI-H508 CTRP1 0.2604 33.3330
Compound 4 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
Compound 4 RKO CTRP1 0.2604 33.3330
Compound 4 SK-CO-1 CTRP1 0.2603 33.3330
Compound 4 SNU-1040 CTRP1 0.2604 33.3330
Compound 4 SNU-175 CTRP1 0.2604 33.3330
Compound 4 SNU-61 CTRP1 0.2604 33.3330
Compound 4 SNU-81 CTRP1 0.2604 33.3330
Compound 4 SNU-C2A CTRP1 0.2603 33.3330
Compound 4 SNU-C4 CTRP1 0.2604 33.3330
Compound 4 SNU-C5 CTRP1 0.2604 33.3330
Compound 4 SW403 CTRP1 0.2603 33.3330
Compound 4 SW48 CTRP1 0.2603 33.3330
Compound 4 SW480 CTRP1 0.2604 33.3330
Compound 4 SW620 CTRP1 0.2604 33.3330
Compound 4 SW948 CTRP1 0.2604 33.3330
Compound 4 HEP-G2 CTRP1 0.2604 33.3330
Compound 4 JHH-6 CTRP1 0.2603 33.3330
Compound 4 SNU-398 CTRP1 0.2604 33.3330
Compound 4 SNU-449 CTRP1 0.2603 33.3330
Compound 4 A-549 CTRP1 0.2603 33.3330
Compound 4 BEN CTRP1 0.2603 33.3330
Compound 4 CAL-12T CTRP1 0.2604 33.3330
Compound 4 CALU-3 CTRP1 0.2603 33.3330
Compound 4 CALU-6 CTRP1 0.2603 33.3330
Compound 4 CHAGO-K-1 CTRP1 0.2603 33.3330
Compound 4 COLO668 CTRP1 0.2603 33.3330
Compound 4 COLO699 CTRP1 0.2604 33.3330
Compound 4 COR-L23 CTRP1 0.2604 33.3330
Compound 4 COR-L279 CTRP1 0.2603 33.3330
Compound 4 COR-L51 CTRP1 0.2604 33.3330
Compound 4 COR-L88 CTRP1 0.2603 33.3330
Compound 4 DMS273 CTRP1 0.2603 33.3330
Compound 4 DV-90 CTRP1 0.2603 33.3330
Compound 4 EBC-1 CTRP1 0.2603 33.3330
Compound 4 EPLC-272H CTRP1 0.2603 33.3330
Compound 4 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
Compound 4 HCC1195 CTRP1 0.2604 33.3330
Compound 4 HCC1359 CTRP1 0.2604 33.3330
Compound 4 HCC15 CTRP1 0.2604 33.3330
Compound 4 HCC1833 CTRP1 0.2604 33.3330
Compound 4 HCC2108 CTRP1 0.2604 33.3330
Compound 4 HCC2935 CTRP1 0.2604 33.3330
Compound 4 HCC33 CTRP1 0.2603 33.3330
Compound 4 HCC4006 CTRP1 0.2604 33.3330
Compound 4 HCC44 CTRP1 0.2603 33.3330
Compound 4 HCC78 CTRP1 0.2603 33.3330
Compound 4 HCC827 CTRP1 0.2604 33.3330
Compound 4 KNS-62 CTRP1 0.2603 33.3330
Compound 4 LC-1-SQ-SF CTRP1 0.2603 33.3330
Compound 4 LCLC-103H CTRP1 0.2603 33.3330
Compound 4 LCLC-97TM1 CTRP1 0.2603 33.3330
Compound 4 LU-65 CTRP1 0.2603 33.3330
Compound 4 LU-99 CTRP1 0.2603 33.3330
Compound 4 LXF289 CTRP1 0.2603 33.3330
Compound 4 NCI-H1048 CTRP1 0.2603 33.3330
Compound 4 NCI-H1105 CTRP1 0.2604 33.3330
Compound 4 NCI-H1299 CTRP1 0.2603 33.3330
Compound 4 NCI-H1355 CTRP1 0.2603 33.3330
Compound 4 NCI-H1373 CTRP1 0.2603 33.3330
Compound 4 NCI-H1435 CTRP1 0.2603 33.3330
Compound 4 NCI-H1437 CTRP1 0.2603 33.3330
Compound 4 NCI-H1568 CTRP1 0.2603 33.3330
Compound 4 NCI-H1573 CTRP1 0.2603 33.3330
Compound 4 NCI-H1666 CTRP1 0.2603 33.3330
Compound 4 NCI-H1694 CTRP1 0.2604 33.3330
Compound 4 NCI-H1755 CTRP1 0.2604 33.3330
Compound 4 NCI-H1781 CTRP1 0.2604 33.3330
Compound 4 NCI-H1792 CTRP1 0.2603 33.3330
Compound 4 NCI-H1793 CTRP1 0.2603 33.3330
Compound 4 NCI-H1836 CTRP1 0.2604 33.3330
Compound 4 NCI-H1876 CTRP1 0.2604 33.3330
Compound 4 NCI-H1915 CTRP1 0.2603 33.3330
Compound 4 NCI-H1930 CTRP1 0.2603 33.3330
Compound 4 NCI-H1944 CTRP1 0.2603 33.3330
Compound 4 NCI-H1963 CTRP1 0.2604 33.3330
Compound 4 NCI-H1975 CTRP1 0.2603 33.3330
Compound 4 NCI-H2009 CTRP1 0.2603 33.3330
Compound 4 NCI-H2023 CTRP1 0.2604 33.3330
Compound 4 NCI-H2029 CTRP1 0.2603 33.3330
Compound 4 NCI-H2030 CTRP1 0.2604 33.3330
Compound 4 NCI-H2073 CTRP1 0.2604 33.3330
Compound 4 NCI-H2081 CTRP1 0.2604 33.3330
Compound 4 NCI-H2110 CTRP1 0.2604 33.3330
Compound 4 NCI-H2122 CTRP1 0.2604 33.3330
Compound 4 NCI-H2126 CTRP1 0.2603 33.3330
Compound 4 NCI-H2141 CTRP1 0.2604 33.3330
Compound 4 NCI-H2172 CTRP1 0.2604 33.3330
Compound 4 NCI-H2286 CTRP1 0.2603 33.3330
Compound 4 NCI-H23 CTRP1 0.2603 33.3330
Compound 4 NCI-H2342 CTRP1 0.2604 33.3330
Compound 4 NCI-H2405 CTRP1 0.2603 33.3330
Compound 4 NCI-H3255 CTRP1 0.2604 33.3330
Compound 4 NCI-H358 CTRP1 0.2603 33.3330
Compound 4 NCI-H441 CTRP1 0.2604 33.3330
Compound 4 NCI-H460 CTRP1 0.2604 33.3330
Compound 4 NCI-H522 CTRP1 0.2603 33.3330
Compound 4 NCI-H596 CTRP1 0.2604 33.3330
Compound 4 NCI-H650 CTRP1 0.2603 33.3330
Compound 4 NCI-H661 CTRP1 0.2603 33.3330
Compound 4 NCI-H727 CTRP1 0.2603 33.3330
Compound 4 NCI-H810 CTRP1 0.2603 33.3330
Compound 4 NCI-H82 CTRP1 0.2603 33.3330
Compound 4 NCI-H841 CTRP1 0.2604 33.3330
Compound 4 RERF-LC-KJ CTRP1 0.2603 33.3330
Compound 4 SCLC-21H CTRP1 0.2604 33.3330
Compound 4 SHP-77 CTRP1 0.2603 33.3330
Compound 4 SK-LU-1 CTRP1 0.2604 33.3330
Compound 4 SQ-1 CTRP1 0.2604 33.3330
Compound 4 T3M-10 CTRP1 0.2604 33.3330
Compound 4 VMRC-LCD CTRP1 0.2603 33.3330
Compound 4 KYSE-140 CTRP1 0.2603 33.3330
Compound 4 KYSE-410 CTRP1 0.2603 33.3330
Compound 4 KYSE-450 CTRP1 0.2603 33.3330
Compound 4 A2780 CTRP1 0.2604 33.3330
Compound 4 CAOV-3 CTRP1 0.2604 33.3330
Compound 4 COV318 CTRP1 0.2603 33.3330
Compound 4 COV362 CTRP1 0.2604 33.3330
Compound 4 COV434 CTRP1 0.2604 33.3330
Compound 4 COV644 CTRP1 0.2604 33.3330
Compound 4 EFO-21 CTRP1 0.2603 33.3330
Compound 4 EFO-27 CTRP1 0.2604 33.3330
Compound 4 HEYA8 CTRP1 0.2603 33.3330
Compound 4 IGROV-1 CTRP1 0.2604 33.3330
Compound 4 JHOC-5 CTRP1 0.2604 33.3330
Compound 4 JHOM-1 CTRP1 0.2604 33.3330
Compound 4 JHOS-4 CTRP1 0.2603 33.3330
Compound 4 OAW42 CTRP1 0.2604 33.3330
Compound 4 OV7 CTRP1 0.2604 33.3330
Compound 4 OV-90 CTRP1 0.2604 33.3330
Compound 4 OVCAR-4 CTRP1 0.2604 33.3330
Compound 4 OVCAR-8 CTRP1 0.2604 33.3330
Compound 4 OVK18 CTRP1 0.2604 33.3330
Compound 4 OVKATE CTRP1 0.2604 33.3330
Compound 4 OVMANA CTRP1 0.2603 33.3330
Compound 4 RKN CTRP1 0.2604 33.3330
Compound 4 RMG-I CTRP1 0.2604 33.3330
Compound 4 RMUG-S CTRP1 0.2604 33.3330
Compound 4 SK-OV-3 CTRP1 0.2603 33.3330
Compound 4 SNU-840 CTRP1 0.2604 33.3330
Compound 4 TYK-NU CTRP1 0.2604 33.3330
Compound 4 CAPAN-2 CTRP1 0.2603 33.3330
Compound 4 CFPAC-1 CTRP1 0.2603 33.3330
Compound 4 HPAC CTRP1 0.2603 33.3330
Compound 4 HUP-T4 CTRP1 0.2603 33.3330
Compound 4 KP-3 CTRP1 0.2603 33.3330
Compound 4 PANC03.27 CTRP1 0.2603 33.3330
Compound 4 PANC10.05 CTRP1 0.2603 33.3330
Compound 4 PATU8902 CTRP1 0.2603 33.3330
Compound 4 QGP-1 CTRP1 0.2603 33.3330
Compound 4 SUIT-2 CTRP1 0.2603 33.3330
Compound 4 MSTO-211H CTRP1 0.2603 33.3330
Compound 4 NCI-H2052 CTRP1 0.2603 33.3330
Compound 4 NCI-H28 CTRP1 0.2603 33.3330
Compound 4 MIAPACA-3 CTRP1 0.2603 33.3330
Compound 4 A-375 CTRP1 0.2604 33.3330
Compound 4 COLO741 CTRP1 0.2603 33.3330
Compound 4 G-361 CTRP1 0.2603 33.3330
Compound 4 HS852.T CTRP1 0.2603 33.3330
Compound 4 HS936.T CTRP1 0.2603 33.3330
Compound 4 HS944.T CTRP1 0.2603 33.3330
Compound 4 SK-MEL-1 CTRP1 0.2604 33.3330
Compound 4 SK-MEL-28 CTRP1 0.2604 33.3330
Compound 4 SK-MEL-5 CTRP1 0.2604 33.3330
Compound 4 G-401 CTRP1 0.2603 33.3330
Compound 4 HT-1080 CTRP1 0.2604 33.3330
Compound 4 AGS CTRP1 0.2604 33.3330
Compound 4 FU97 CTRP1 0.2603 33.3330
Compound 4 KE-97 CTRP1 0.2603 33.3330
Compound 4 MKN7 CTRP1 0.2603 33.3330
Compound 4 MKN74 CTRP1 0.2603 33.3330
Compound 4 NUGC-4 CTRP1 0.2603 33.3330
Compound 4 SH-10-TC CTRP1 0.2603 33.3330
Compound 4 HSC-2 CTRP1 0.2603 33.3330
Compound 4 SCC-9 CTRP1 0.2604 33.3330
Compound 4 5637 CTRP1 0.2603 33.3330
Compound 4 HT-1376 CTRP1 0.2603 33.3330
Compound 4 KMBC-2 CTRP1 0.2603 33.3330
Compound 4 RT-4 CTRP1 0.2603 33.3330
Compound 4 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.