Drug : Brd8418

CTRP1 Name : BRD8418

Dataset : All
Synonyms :
Targets :
Pathways : product of diversity-oriented synthesis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD8418 MCF-7 CTRP1 0.6250 80.0000
BRD8418 LN-229 CTRP1 0.6250 80.0000
BRD8418 HEC-151 CTRP1 0.6250 80.0000
BRD8418 JHUEM-2 CTRP1 0.6250 80.0000
BRD8418 AMO1 CTRP1 0.6250 80.0000
BRD8418 EJM CTRP1 0.6250 80.0000
BRD8418 GDM-1 CTRP1 0.6250 80.0000
BRD8418 KMS-11 CTRP1 0.6250 80.0000
BRD8418 LP-1 CTRP1 0.6250 80.0000
BRD8418 MOLM-16 CTRP1 0.6250 80.0000
BRD8418 NOMO-1 CTRP1 0.6250 80.0000
BRD8418 NU-DUL-1 CTRP1 0.6250 80.0000
BRD8418 OCI-AML-3 CTRP1 0.6250 80.0000
BRD8418 OCI-LY10 CTRP1 0.6250 80.0000
BRD8418 PL21 CTRP1 0.6250 80.0000
BRD8418 RPMI-8226 CTRP1 0.6250 80.0000
BRD8418 SKM-1 CTRP1 0.6250 80.0000
BRD8418 SU-DHL-4 CTRP1 0.6250 80.0000
BRD8418 SU-DHL-5 CTRP1 0.6250 80.0000
BRD8418 THP-1 CTRP1 0.6250 80.0000
BRD8418 U-937 CTRP1 0.6250 80.0000
BRD8418 WSU-DLCL2 CTRP1 0.6250 80.0000
BRD8418 RCC10RGB CTRP1 0.6250 80.0000
BRD8418 CL-34 CTRP1 0.6250 80.0000
BRD8418 CL-40 CTRP1 0.6250 80.0000
BRD8418 COLO320 CTRP1 0.6250 80.0000
BRD8418 COLO678 CTRP1 0.6250 80.0000
BRD8418 CW-2 CTRP1 0.6250 80.0000
BRD8418 HCT116 CTRP1 0.6250 80.0000
BRD8418 HCT8 CTRP1 0.6250 80.0000
BRD8418 HT115 CTRP1 0.6250 80.0000
BRD8418 HT-29 CTRP1 0.6250 80.0000
BRD8418 HT-55 CTRP1 0.6250 80.0000
BRD8418 KM12 CTRP1 0.6250 80.0000
BRD8418 LOVO CTRP1 0.6250 80.0000
BRD8418 LS123 CTRP1 0.6250 80.0000
BRD8418 LS180 CTRP1 0.6250 80.0000
BRD8418 MDST8 CTRP1 0.6250 80.0000
BRD8418 NCI-H508 CTRP1 0.6250 80.0000
BRD8418 RCM-1[HUMANESC] CTRP1 0.6250 80.0000
BRD8418 RKO CTRP1 0.6250 80.0000
BRD8418 SNU-1040 CTRP1 0.6250 80.0000
BRD8418 SNU-175 CTRP1 0.6250 80.0000
BRD8418 SNU-61 CTRP1 0.6250 80.0000
BRD8418 SNU-81 CTRP1 0.6250 80.0000
BRD8418 SNU-C4 CTRP1 0.6250 80.0000
BRD8418 SNU-C5 CTRP1 0.6250 80.0000
BRD8418 SW480 CTRP1 0.6250 80.0000
BRD8418 SW620 CTRP1 0.6250 80.0000
BRD8418 SW948 CTRP1 0.6250 80.0000
BRD8418 HEP-G2 CTRP1 0.6250 80.0000
BRD8418 SNU-398 CTRP1 0.6250 80.0000
BRD8418 CAL-12T CTRP1 0.6250 80.0000
BRD8418 COLO699 CTRP1 0.6250 80.0000
BRD8418 COR-L23 CTRP1 0.6250 80.0000
BRD8418 COR-L51 CTRP1 0.6250 80.0000
BRD8418 HCC1195 CTRP1 0.6250 80.0000
BRD8418 HCC1359 CTRP1 0.6250 80.0000
BRD8418 HCC15 CTRP1 0.6250 80.0000
BRD8418 HCC1833 CTRP1 0.6250 80.0000
BRD8418 HCC2108 CTRP1 0.6250 80.0000
BRD8418 HCC2935 CTRP1 0.6250 80.0000
BRD8418 HCC4006 CTRP1 0.6250 80.0000
BRD8418 HCC827 CTRP1 0.6250 80.0000
BRD8418 NCI-H1105 CTRP1 0.6250 80.0000
BRD8418 NCI-H1694 CTRP1 0.6250 80.0000
BRD8418 NCI-H1755 CTRP1 0.6250 80.0000
BRD8418 NCI-H1781 CTRP1 0.6250 80.0000
BRD8418 NCI-H1836 CTRP1 0.6250 80.0000
BRD8418 NCI-H1876 CTRP1 0.6250 80.0000
BRD8418 NCI-H1963 CTRP1 0.6250 80.0000
BRD8418 NCI-H2023 CTRP1 0.6250 80.0000
BRD8418 NCI-H2030 CTRP1 0.6250 80.0000
BRD8418 NCI-H2073 CTRP1 0.6250 80.0000
BRD8418 NCI-H2081 CTRP1 0.6250 80.0000
BRD8418 NCI-H2110 CTRP1 0.6250 80.0000
BRD8418 NCI-H2122 CTRP1 0.6250 80.0000
BRD8418 NCI-H2141 CTRP1 0.6250 80.0000
BRD8418 NCI-H2172 CTRP1 0.6250 80.0000
BRD8418 NCI-H2342 CTRP1 0.6250 80.0000
BRD8418 NCI-H3255 CTRP1 0.6250 80.0000
BRD8418 NCI-H441 CTRP1 0.6250 80.0000
BRD8418 NCI-H460 CTRP1 0.6250 80.0000
BRD8418 NCI-H596 CTRP1 0.6250 80.0000
BRD8418 NCI-H841 CTRP1 0.6250 80.0000
BRD8418 SCLC-21H CTRP1 0.6250 80.0000
BRD8418 SK-LU-1 CTRP1 0.6250 80.0000
BRD8418 SQ-1 CTRP1 0.6250 80.0000
BRD8418 T3M-10 CTRP1 0.6250 80.0000
BRD8418 A2780 CTRP1 0.6250 80.0000
BRD8418 CAOV-3 CTRP1 0.6250 80.0000
BRD8418 COV362 CTRP1 0.6250 80.0000
BRD8418 COV434 CTRP1 0.6250 80.0000
BRD8418 COV644 CTRP1 0.6250 80.0000
BRD8418 EFO-27 CTRP1 0.6250 80.0000
BRD8418 IGROV-1 CTRP1 0.6250 80.0000
BRD8418 JHOC-5 CTRP1 0.6250 80.0000
BRD8418 JHOM-1 CTRP1 0.6250 80.0000
BRD8418 OAW42 CTRP1 0.6250 80.0000
BRD8418 OV7 CTRP1 0.6250 80.0000
BRD8418 OV-90 CTRP1 0.6250 80.0000
BRD8418 OVCAR-4 CTRP1 0.6250 80.0000
BRD8418 OVCAR-8 CTRP1 0.6250 80.0000
BRD8418 OVK18 CTRP1 0.6250 80.0000
BRD8418 OVKATE CTRP1 0.6250 80.0000
BRD8418 RKN CTRP1 0.6250 80.0000
BRD8418 RMG-I CTRP1 0.6250 80.0000
BRD8418 RMUG-S CTRP1 0.6250 80.0000
BRD8418 SNU-840 CTRP1 0.6250 80.0000
BRD8418 TYK-NU CTRP1 0.6250 80.0000
BRD8418 A-375 CTRP1 0.6250 80.0000
BRD8418 SK-MEL-1 CTRP1 0.6250 80.0000
BRD8418 SK-MEL-28 CTRP1 0.6250 80.0000
BRD8418 SK-MEL-5 CTRP1 0.6250 80.0000
BRD8418 HT-1080 CTRP1 0.6250 80.0000
BRD8418 AGS CTRP1 0.6250 80.0000
BRD8418 SCC-9 CTRP1 0.6250 80.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.