Drug : Penfluridol

CTRP1 Name : penfluridol

Dataset : All
Synonyms :
Targets : DRD2;CACNA1G;CACNA1H;CACNA1I
Pathways : antagonist of dopamine receptors;inhibitor of T-type calcium channel

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
penfluridol MCF-7 CTRP1 0.7813 100.0000
penfluridol LN-229 CTRP1 0.7813 100.0000
penfluridol JHUEM-2 CTRP1 0.7813 100.0000
penfluridol EJM CTRP1 0.7813 100.0000
penfluridol GDM-1 CTRP1 0.7813 100.0000
penfluridol MOLM-16 CTRP1 0.7813 100.0000
penfluridol NOMO-1 CTRP1 0.7813 100.0000
penfluridol NU-DUL-1 CTRP1 0.7813 100.0000
penfluridol OCI-AML-3 CTRP1 0.7813 100.0000
penfluridol PL21 CTRP1 0.7813 100.0000
penfluridol RPMI-8226 CTRP1 0.7813 100.0000
penfluridol SKM-1 CTRP1 0.7813 100.0000
penfluridol SU-DHL-4 CTRP1 0.7813 100.0000
penfluridol SU-DHL-5 CTRP1 0.7813 100.0000
penfluridol THP-1 CTRP1 0.7813 100.0000
penfluridol U-937 CTRP1 0.7813 100.0000
penfluridol WSU-DLCL2 CTRP1 0.7813 100.0000
penfluridol CL-34 CTRP1 0.7813 100.0000
penfluridol CL-40 CTRP1 0.7813 100.0000
penfluridol COLO320 CTRP1 0.7813 100.0000
penfluridol COLO678 CTRP1 0.7813 100.0000
penfluridol CW-2 CTRP1 0.7813 100.0000
penfluridol HCT116 CTRP1 0.7813 100.0000
penfluridol HCT8 CTRP1 0.7813 100.0000
penfluridol HT115 CTRP1 0.7813 100.0000
penfluridol HT-29 CTRP1 0.7813 100.0000
penfluridol HT-55 CTRP1 0.7813 100.0000
penfluridol KM12 CTRP1 0.7813 100.0000
penfluridol LOVO CTRP1 0.7813 100.0000
penfluridol LS123 CTRP1 0.7813 100.0000
penfluridol MDST8 CTRP1 0.7813 100.0000
penfluridol NCI-H508 CTRP1 0.7813 100.0000
penfluridol RCM-1[HUMANESC] CTRP1 0.7813 100.0000
penfluridol RKO CTRP1 0.7813 100.0000
penfluridol SNU-1040 CTRP1 0.7813 100.0000
penfluridol SNU-175 CTRP1 0.7813 100.0000
penfluridol SNU-61 CTRP1 0.7813 100.0000
penfluridol SNU-81 CTRP1 0.7813 100.0000
penfluridol SNU-C4 CTRP1 0.7813 100.0000
penfluridol SNU-C5 CTRP1 0.7813 100.0000
penfluridol SW480 CTRP1 0.7813 100.0000
penfluridol SW620 CTRP1 0.7813 100.0000
penfluridol SW948 CTRP1 0.7813 100.0000
penfluridol HEP-G2 CTRP1 0.7813 100.0000
penfluridol CAL-12T CTRP1 0.7813 100.0000
penfluridol COLO699 CTRP1 0.7813 100.0000
penfluridol COR-L23 CTRP1 0.7813 100.0000
penfluridol HCC1195 CTRP1 0.7813 100.0000
penfluridol HCC1359 CTRP1 0.7813 100.0000
penfluridol HCC15 CTRP1 0.7813 100.0000
penfluridol HCC1833 CTRP1 0.7813 100.0000
penfluridol HCC2108 CTRP1 0.7813 100.0000
penfluridol HCC2935 CTRP1 0.7813 100.0000
penfluridol HCC4006 CTRP1 0.7813 100.0000
penfluridol HCC827 CTRP1 0.7813 100.0000
penfluridol NCI-H1105 CTRP1 0.7813 100.0000
penfluridol NCI-H1694 CTRP1 0.7813 100.0000
penfluridol NCI-H1755 CTRP1 0.7813 100.0000
penfluridol NCI-H1781 CTRP1 0.7813 100.0000
penfluridol NCI-H1836 CTRP1 0.7813 100.0000
penfluridol NCI-H1876 CTRP1 0.7813 100.0000
penfluridol NCI-H2023 CTRP1 0.7813 100.0000
penfluridol NCI-H2030 CTRP1 0.7813 100.0000
penfluridol NCI-H2073 CTRP1 0.7813 100.0000
penfluridol NCI-H2081 CTRP1 0.7813 100.0000
penfluridol NCI-H2110 CTRP1 0.7813 100.0000
penfluridol NCI-H2122 CTRP1 0.7813 100.0000
penfluridol NCI-H2172 CTRP1 0.7813 100.0000
penfluridol NCI-H2342 CTRP1 0.7813 100.0000
penfluridol NCI-H3255 CTRP1 0.7813 100.0000
penfluridol NCI-H441 CTRP1 0.7813 100.0000
penfluridol NCI-H460 CTRP1 0.7813 100.0000
penfluridol NCI-H596 CTRP1 0.7813 100.0000
penfluridol NCI-H841 CTRP1 0.7813 100.0000
penfluridol SK-LU-1 CTRP1 0.7813 100.0000
penfluridol SQ-1 CTRP1 0.7813 100.0000
penfluridol T3M-10 CTRP1 0.7813 100.0000
penfluridol CAOV-3 CTRP1 0.7813 100.0000
penfluridol COV362 CTRP1 0.7813 100.0000
penfluridol COV434 CTRP1 0.7813 100.0000
penfluridol COV644 CTRP1 0.7813 100.0000
penfluridol EFO-27 CTRP1 0.7813 100.0000
penfluridol JHOC-5 CTRP1 0.7813 100.0000
penfluridol JHOM-1 CTRP1 0.7813 100.0000
penfluridol OAW42 CTRP1 0.7813 100.0000
penfluridol OV7 CTRP1 0.7813 100.0000
penfluridol OV-90 CTRP1 0.7813 100.0000
penfluridol OVK18 CTRP1 0.7813 100.0000
penfluridol RMG-I CTRP1 0.7813 100.0000
penfluridol RMUG-S CTRP1 0.7813 100.0000
penfluridol SNU-840 CTRP1 0.7813 100.0000
penfluridol TYK-NU CTRP1 0.7813 100.0000
penfluridol A-375 CTRP1 0.7813 100.0000
penfluridol SK-MEL-1 CTRP1 0.7813 100.0000
penfluridol SK-MEL-28 CTRP1 0.7813 100.0000
penfluridol SK-MEL-5 CTRP1 0.7813 100.0000
penfluridol HT-1080 CTRP1 0.7813 100.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.