Drug : 4-Ipp
CTRP1 Name
: 4-IPP
Dataset : All
Synonyms :
Targets : MIF
Pathways : Inhibitor of macrophage migration inhibitory factor
Information Cards
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Drug name | Cellosaurus ID | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| 4-IPP | U2OS | CTRP1 | 1.0417 | 133.3300 |
|
| 4-IPP | MCF-7 | CTRP1 | 1.0417 | 133.3300 |
|
| 4-IPP | GAMG | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | LN-229 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SF295 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HEC-108 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HEC-151 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HEC-251 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HEC-265 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HEC-59 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HEC-6 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | ISHIKAWA(HERAKLIO)02ER- | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | JHUEM-2 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | KLE | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MFE-319 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SNG-M | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | AMO1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | BL-70 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | EJM | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | GDM-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HT | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KMS-11 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | KU812 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | LP-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | MC116 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MOLM-16 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NOMO-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NU-DUL-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OCI-AML-3 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OCI-LY10 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | P3HR-1 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | PL21 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RPMI-8226 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SKM-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SU-DHL-4 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SU-DHL-5 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | THP-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | U-937 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | WSU-DLCL2 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RCC10RGB | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | VMRC-RCW | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | CL-34 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | CL-40 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COLO320 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COLO678 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | CW-2 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCT116 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCT8 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HT115 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HT-29 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HT-55 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | KM12 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | LOVO | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | LS123 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | LS180 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | MDST8 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H508 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RCM-1[HUMANESC] | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RKO | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-1040 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-175 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-61 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-81 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-C2A | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SNU-C4 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-C5 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SW403 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SW480 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SW620 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SW948 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HEP-G2 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | JHH-6 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SNU-398 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SNU-449 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | A-549 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | CAL-12T | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | CALU-3 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | CALU-6 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | CHAGO-K-1 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | COLO668 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | COLO699 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COR-L23 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COR-L279 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | COR-L51 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COR-L88 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | DMS273 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | EPLC-272H | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HCC1195 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC1359 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC15 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC1833 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC2108 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC2935 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC4006 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HCC827 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | KNS-62 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | LCLC-97TM1 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | LXF289 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1048 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1105 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1299 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1355 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1435 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1437 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1568 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1573 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1666 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1694 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1755 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1781 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1792 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1836 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1876 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1915 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1930 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1944 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H1963 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H1975 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H2009 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H2023 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2029 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H2030 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2073 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2081 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2110 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2122 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2141 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2172 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2286 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H23 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H2342 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H2405 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H3255 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H441 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H460 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H596 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | NCI-H650 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H810 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H82 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H841 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RERF-LC-KJ | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SCLC-21H | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SK-LU-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SQ-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | T3M-10 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | VMRC-LCD | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KYSE-140 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KYSE-410 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KYSE-450 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | A2780 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | CAOV-3 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COV318 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | COV362 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COV434 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | COV644 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | EFO-21 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | EFO-27 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | HEYA8 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | IGROV-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | JHOC-5 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | JHOM-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | JHOS-4 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | OAW42 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OV7 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OV-90 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OVCAR-4 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OVCAR-8 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OVK18 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OVKATE | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | OVMANA | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | RKN | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RMG-I | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | RMUG-S | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SK-OV-3 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SNU-840 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | TYK-NU | CTRP1 | 1.0417 | 133.3300 |
|
| 4-IPP | CAPAN-2 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HUP-T4 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KP-3 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | PANC03.27 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | PATU8902 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | QGP-1 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SUIT-2 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MSTO-211H | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H2052 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NCI-H28 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MIAPACA-3 | CTRP1 | 0.2603 | 33.3330 |
|
| 4-IPP | A-375 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | G-361 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HS852.T | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HS936.T | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HS944.T | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SK-MEL-1 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SK-MEL-28 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | SK-MEL-5 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | G-401 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HT-1080 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | AGS | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | FU97 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KE-97 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MKN7 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | MKN74 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | NUGC-4 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SH-10-TC | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HSC-2 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | SCC-9 | CTRP1 | 1.0417 | 133.3300 |
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| 4-IPP | 5637 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | HT-1376 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | KMBC-2 | CTRP1 | 0.2603 | 33.3330 |
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| 4-IPP | RT-4 | CTRP1 | 0.2603 | 33.3330 |
|
| 4-IPP | UM-UC-3 | CTRP1 | 0.2603 | 33.3330 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Cell lines with highest and lowest IC50
Cell lines with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Cell lines with highest and lowest IC90
Cell lines with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Cell lines with highest and lowest AUC
Cell lines with highest and lowest AUC
Associated Genes (Mutation)
Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from
pancan data.
Associated Genes (Gene Expression)
Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from
pancan data.