CREAMMIST

Drug : Telomerase Inhibitor Ix

CTRP1 Name , CTRP2 Name : MST-312
GDSC1 Name , GDSC2 Name : Telomerase Inhibitor IX

Dataset : All
Synonyms :
Targets : Telomerase
Pathways : Genome integrity

Information Cards

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Experiment Information IC50 IC90 AUC
Associated Genes (Mutation) Associated Genes (Gene Expression)

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

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Drug name	Cellosaurus ID	Original Dataset(s)	Min Dose	Max Dose
Telomerase Inhibitor IX	U2OS	GDSC2,CTRP1	0.0100	37.0000
Telomerase Inhibitor IX	MCF-7	GDSC2,CTRP1	0.0100	37.0000
Telomerase Inhibitor IX	GAMG	GDSC2,CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	LN-229	GDSC2,CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	SF295	GDSC2,CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	HEC-108	CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	HEC-151	CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	HEC-251	CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	HEC-265	CTRP2,CTRP1	0.0010	37.0000
Telomerase Inhibitor IX	HEC-59	CTRP2,CTRP1	0.0010	37.0000

Showing 1 to 10 of 1,280 entries

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.