Drug : Brd2572

CTRP1 Name : BRD2572

Dataset : All
Synonyms :
Targets :
Pathways : product of diversity-oriented synthesis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD2572 MCF-7 CTRP1 0.6250 80.0000
BRD2572 LN-229 CTRP1 0.6250 80.0000
BRD2572 HEC-151 CTRP1 0.3125 80.0000
BRD2572 JHUEM-2 CTRP1 0.6250 80.0000
BRD2572 AMO1 CTRP1 0.3125 80.0000
BRD2572 EJM CTRP1 0.6250 80.0000
BRD2572 GDM-1 CTRP1 0.6250 80.0000
BRD2572 KMS-11 CTRP1 0.3125 80.0000
BRD2572 LP-1 CTRP1 0.3125 80.0000
BRD2572 MOLM-16 CTRP1 0.6250 80.0000
BRD2572 NOMO-1 CTRP1 0.6250 80.0000
BRD2572 NU-DUL-1 CTRP1 0.6250 80.0000
BRD2572 OCI-AML-3 CTRP1 0.6250 80.0000
BRD2572 OCI-LY10 CTRP1 0.3125 80.0000
BRD2572 PL21 CTRP1 0.6250 80.0000
BRD2572 RPMI-8226 CTRP1 0.6250 80.0000
BRD2572 SKM-1 CTRP1 0.6250 80.0000
BRD2572 SU-DHL-4 CTRP1 0.6250 80.0000
BRD2572 SU-DHL-5 CTRP1 0.6250 80.0000
BRD2572 THP-1 CTRP1 0.6250 80.0000
BRD2572 U-937 CTRP1 0.6250 80.0000
BRD2572 WSU-DLCL2 CTRP1 0.6250 80.0000
BRD2572 CL-34 CTRP1 0.6250 80.0000
BRD2572 CL-40 CTRP1 0.6250 80.0000
BRD2572 COLO320 CTRP1 0.6250 80.0000
BRD2572 COLO678 CTRP1 0.6250 80.0000
BRD2572 CW-2 CTRP1 0.6250 80.0000
BRD2572 HCT116 CTRP1 0.6250 80.0000
BRD2572 HCT8 CTRP1 0.6250 80.0000
BRD2572 HT115 CTRP1 0.6250 80.0000
BRD2572 HT-29 CTRP1 0.6250 80.0000
BRD2572 HT-55 CTRP1 0.6250 80.0000
BRD2572 KM12 CTRP1 0.6250 80.0000
BRD2572 LOVO CTRP1 0.6250 80.0000
BRD2572 LS123 CTRP1 0.6250 80.0000
BRD2572 LS180 CTRP1 0.3125 80.0000
BRD2572 MDST8 CTRP1 0.6250 80.0000
BRD2572 NCI-H508 CTRP1 0.6250 80.0000
BRD2572 RCM-1[HUMANESC] CTRP1 0.6250 80.0000
BRD2572 RKO CTRP1 0.6250 80.0000
BRD2572 SNU-1040 CTRP1 0.6250 80.0000
BRD2572 SNU-175 CTRP1 0.6250 80.0000
BRD2572 SNU-61 CTRP1 0.6250 80.0000
BRD2572 SNU-81 CTRP1 0.6250 80.0000
BRD2572 SNU-C4 CTRP1 0.6250 80.0000
BRD2572 SNU-C5 CTRP1 0.6250 80.0000
BRD2572 SW480 CTRP1 0.6250 80.0000
BRD2572 SW620 CTRP1 0.6250 80.0000
BRD2572 SW948 CTRP1 0.6250 80.0000
BRD2572 HEP-G2 CTRP1 0.6250 80.0000
BRD2572 SNU-398 CTRP1 0.3125 80.0000
BRD2572 CAL-12T CTRP1 0.6250 80.0000
BRD2572 COLO699 CTRP1 0.6250 80.0000
BRD2572 COR-L23 CTRP1 0.6250 80.0000
BRD2572 COR-L51 CTRP1 0.3125 80.0000
BRD2572 HCC1195 CTRP1 0.6250 80.0000
BRD2572 HCC1359 CTRP1 0.6250 80.0000
BRD2572 HCC15 CTRP1 0.6250 80.0000
BRD2572 HCC1833 CTRP1 0.6250 80.0000
BRD2572 HCC2108 CTRP1 0.6250 80.0000
BRD2572 HCC2935 CTRP1 0.6250 80.0000
BRD2572 HCC4006 CTRP1 0.6250 80.0000
BRD2572 HCC827 CTRP1 0.6250 80.0000
BRD2572 NCI-H1105 CTRP1 0.6250 80.0000
BRD2572 NCI-H1694 CTRP1 0.6250 80.0000
BRD2572 NCI-H1755 CTRP1 0.6250 80.0000
BRD2572 NCI-H1781 CTRP1 0.6250 80.0000
BRD2572 NCI-H1836 CTRP1 0.6250 80.0000
BRD2572 NCI-H1876 CTRP1 0.6250 80.0000
BRD2572 NCI-H1963 CTRP1 0.3125 80.0000
BRD2572 NCI-H2023 CTRP1 0.6250 80.0000
BRD2572 NCI-H2030 CTRP1 0.6250 80.0000
BRD2572 NCI-H2073 CTRP1 0.6250 80.0000
BRD2572 NCI-H2081 CTRP1 0.6250 80.0000
BRD2572 NCI-H2110 CTRP1 0.6250 80.0000
BRD2572 NCI-H2122 CTRP1 0.6250 80.0000
BRD2572 NCI-H2141 CTRP1 0.3125 80.0000
BRD2572 NCI-H2172 CTRP1 0.6250 80.0000
BRD2572 NCI-H2342 CTRP1 0.6250 80.0000
BRD2572 NCI-H3255 CTRP1 0.6250 80.0000
BRD2572 NCI-H441 CTRP1 0.6250 80.0000
BRD2572 NCI-H460 CTRP1 0.6250 80.0000
BRD2572 NCI-H596 CTRP1 0.6250 80.0000
BRD2572 NCI-H841 CTRP1 0.6250 80.0000
BRD2572 SCLC-21H CTRP1 0.3125 80.0000
BRD2572 SK-LU-1 CTRP1 0.6250 80.0000
BRD2572 SQ-1 CTRP1 0.6250 80.0000
BRD2572 T3M-10 CTRP1 0.6250 80.0000
BRD2572 A2780 CTRP1 0.3125 80.0000
BRD2572 CAOV-3 CTRP1 0.6250 80.0000
BRD2572 COV362 CTRP1 0.6250 80.0000
BRD2572 COV434 CTRP1 0.6250 80.0000
BRD2572 COV644 CTRP1 0.6250 80.0000
BRD2572 EFO-27 CTRP1 0.6250 80.0000
BRD2572 IGROV-1 CTRP1 0.3125 80.0000
BRD2572 JHOC-5 CTRP1 0.6250 80.0000
BRD2572 JHOM-1 CTRP1 0.6250 80.0000
BRD2572 OAW42 CTRP1 0.6250 80.0000
BRD2572 OV7 CTRP1 0.6250 80.0000
BRD2572 OV-90 CTRP1 0.6250 80.0000
BRD2572 OVCAR-4 CTRP1 0.3125 80.0000
BRD2572 OVCAR-8 CTRP1 0.3125 80.0000
BRD2572 OVK18 CTRP1 0.6250 80.0000
BRD2572 OVKATE CTRP1 0.3125 80.0000
BRD2572 RKN CTRP1 0.3125 80.0000
BRD2572 RMG-I CTRP1 0.6250 80.0000
BRD2572 RMUG-S CTRP1 0.6250 80.0000
BRD2572 SNU-840 CTRP1 0.6250 80.0000
BRD2572 TYK-NU CTRP1 0.6250 80.0000
BRD2572 A-375 CTRP1 0.6250 80.0000
BRD2572 SK-MEL-1 CTRP1 0.6250 80.0000
BRD2572 SK-MEL-28 CTRP1 0.6250 80.0000
BRD2572 SK-MEL-5 CTRP1 0.6250 80.0000
BRD2572 HT-1080 CTRP1 0.6250 80.0000
BRD2572 AGS CTRP1 0.3125 80.0000
BRD2572 SCC-9 CTRP1 0.3125 80.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.