Drug : Ml150

CTRP1 Name : ML150

Dataset : All
Synonyms :
Targets :
Pathways : inhibitor of alpha-synuclein 5'UTR-dependent expression

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
ML150 U2OS CTRP1 0.2604 33.3330
ML150 MCF-7 CTRP1 0.2604 33.3330
ML150 GAMG CTRP1 0.2603 33.3330
ML150 LN-229 CTRP1 0.2604 33.3330
ML150 HEC-108 CTRP1 0.2603 33.3330
ML150 HEC-151 CTRP1 0.2604 33.3330
ML150 HEC-59 CTRP1 0.2603 33.3330
ML150 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
ML150 JHUEM-2 CTRP1 0.2604 33.3330
ML150 KLE CTRP1 0.2603 33.3330
ML150 SNG-M CTRP1 0.2603 33.3330
ML150 AMO1 CTRP1 0.2604 33.3330
ML150 BL-70 CTRP1 0.2603 33.3330
ML150 EJM CTRP1 0.2604 33.3330
ML150 GDM-1 CTRP1 0.2604 33.3330
ML150 KMS-11 CTRP1 0.2604 33.3330
ML150 LP-1 CTRP1 0.2604 33.3330
ML150 MOLM-16 CTRP1 0.2604 33.3330
ML150 NOMO-1 CTRP1 0.2604 33.3330
ML150 NU-DUL-1 CTRP1 0.2604 33.3330
ML150 OCI-AML-3 CTRP1 0.2604 33.3330
ML150 OCI-LY10 CTRP1 0.2604 33.3330
ML150 PL21 CTRP1 0.2604 33.3330
ML150 RPMI-8226 CTRP1 0.2604 33.3330
ML150 SKM-1 CTRP1 0.2604 33.3330
ML150 SU-DHL-4 CTRP1 0.2604 33.3330
ML150 SU-DHL-5 CTRP1 0.2604 33.3330
ML150 THP-1 CTRP1 0.2604 33.3330
ML150 U-937 CTRP1 0.2604 33.3330
ML150 WSU-DLCL2 CTRP1 0.2604 33.3330
ML150 RCC10RGB CTRP1 0.2604 33.3330
ML150 CL-34 CTRP1 0.2604 33.3330
ML150 CL-40 CTRP1 0.2604 33.3330
ML150 COLO320 CTRP1 0.2604 33.3330
ML150 COLO678 CTRP1 0.2604 33.3330
ML150 CW-2 CTRP1 0.2604 33.3330
ML150 HCT116 CTRP1 0.2604 33.3330
ML150 HCT8 CTRP1 0.2604 33.3330
ML150 HT115 CTRP1 0.2604 33.3330
ML150 HT-29 CTRP1 0.2604 33.3330
ML150 HT-55 CTRP1 0.2604 33.3330
ML150 KM12 CTRP1 0.2604 33.3330
ML150 LOVO CTRP1 0.2604 33.3330
ML150 LS123 CTRP1 0.2604 33.3330
ML150 LS180 CTRP1 0.2604 33.3330
ML150 MDST8 CTRP1 0.2604 33.3330
ML150 NCI-H508 CTRP1 0.2604 33.3330
ML150 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
ML150 RKO CTRP1 0.2604 33.3330
ML150 SNU-1040 CTRP1 0.2604 33.3330
ML150 SNU-175 CTRP1 0.2604 33.3330
ML150 SNU-61 CTRP1 0.2604 33.3330
ML150 SNU-81 CTRP1 0.2604 33.3330
ML150 SNU-C4 CTRP1 0.2604 33.3330
ML150 SNU-C5 CTRP1 0.2604 33.3330
ML150 SW480 CTRP1 0.2604 33.3330
ML150 SW620 CTRP1 0.2604 33.3330
ML150 SW948 CTRP1 0.2604 33.3330
ML150 HEP-G2 CTRP1 0.2604 33.3330
ML150 JHH-6 CTRP1 0.2603 33.3330
ML150 SNU-398 CTRP1 0.2604 33.3330
ML150 SNU-449 CTRP1 0.2603 33.3330
ML150 CAL-12T CTRP1 0.2604 33.3330
ML150 COLO668 CTRP1 0.2603 33.3330
ML150 COLO699 CTRP1 0.2604 33.3330
ML150 COR-L23 CTRP1 0.2604 33.3330
ML150 COR-L51 CTRP1 0.2604 33.3330
ML150 HCC1195 CTRP1 0.2604 33.3330
ML150 HCC1359 CTRP1 0.2604 33.3330
ML150 HCC15 CTRP1 0.2604 33.3330
ML150 HCC1833 CTRP1 0.2604 33.3330
ML150 HCC2108 CTRP1 0.2604 33.3330
ML150 HCC2935 CTRP1 0.2604 33.3330
ML150 HCC4006 CTRP1 0.2604 33.3330
ML150 HCC827 CTRP1 0.2604 33.3330
ML150 LXF289 CTRP1 0.2603 33.3330
ML150 NCI-H1105 CTRP1 0.2604 33.3330
ML150 NCI-H1435 CTRP1 0.2603 33.3330
ML150 NCI-H1694 CTRP1 0.2604 33.3330
ML150 NCI-H1755 CTRP1 0.2604 33.3330
ML150 NCI-H1781 CTRP1 0.2604 33.3330
ML150 NCI-H1836 CTRP1 0.2604 33.3330
ML150 NCI-H1876 CTRP1 0.2604 33.3330
ML150 NCI-H1915 CTRP1 0.2603 33.3330
ML150 NCI-H1930 CTRP1 0.2603 33.3330
ML150 NCI-H1963 CTRP1 0.2604 33.3330
ML150 NCI-H2023 CTRP1 0.2604 33.3330
ML150 NCI-H2030 CTRP1 0.2604 33.3330
ML150 NCI-H2073 CTRP1 0.2604 33.3330
ML150 NCI-H2081 CTRP1 0.2604 33.3330
ML150 NCI-H2110 CTRP1 0.2604 33.3330
ML150 NCI-H2122 CTRP1 0.2604 33.3330
ML150 NCI-H2141 CTRP1 0.2604 33.3330
ML150 NCI-H2172 CTRP1 0.2604 33.3330
ML150 NCI-H2286 CTRP1 0.2603 33.3330
ML150 NCI-H2342 CTRP1 0.2604 33.3330
ML150 NCI-H3255 CTRP1 0.2604 33.3330
ML150 NCI-H441 CTRP1 0.2604 33.3330
ML150 NCI-H460 CTRP1 0.2604 33.3330
ML150 NCI-H596 CTRP1 0.2604 33.3330
ML150 NCI-H841 CTRP1 0.2604 33.3330
ML150 RERF-LC-KJ CTRP1 0.2603 33.3330
ML150 SCLC-21H CTRP1 0.2604 33.3330
ML150 SK-LU-1 CTRP1 0.2604 33.3330
ML150 SQ-1 CTRP1 0.2604 33.3330
ML150 T3M-10 CTRP1 0.2604 33.3330
ML150 A2780 CTRP1 0.2604 33.3330
ML150 CAOV-3 CTRP1 0.2604 33.3330
ML150 COV318 CTRP1 0.2603 33.3330
ML150 COV362 CTRP1 0.2604 33.3330
ML150 COV434 CTRP1 0.2604 33.3330
ML150 COV644 CTRP1 0.2604 33.3330
ML150 EFO-27 CTRP1 0.2604 33.3330
ML150 IGROV-1 CTRP1 0.2604 33.3330
ML150 JHOC-5 CTRP1 0.2604 33.3330
ML150 JHOM-1 CTRP1 0.2604 33.3330
ML150 JHOS-4 CTRP1 0.2603 33.3330
ML150 OAW42 CTRP1 0.2604 33.3330
ML150 OV7 CTRP1 0.2604 33.3330
ML150 OV-90 CTRP1 0.2604 33.3330
ML150 OVCAR-4 CTRP1 0.2604 33.3330
ML150 OVCAR-8 CTRP1 0.2604 33.3330
ML150 OVK18 CTRP1 0.2604 33.3330
ML150 OVKATE CTRP1 0.2604 33.3330
ML150 OVMANA CTRP1 0.2603 33.3330
ML150 RKN CTRP1 0.2604 33.3330
ML150 RMG-I CTRP1 0.2604 33.3330
ML150 RMUG-S CTRP1 0.2604 33.3330
ML150 SNU-840 CTRP1 0.2604 33.3330
ML150 TYK-NU CTRP1 0.2604 33.3330
ML150 PATU8902 CTRP1 0.2603 33.3330
ML150 MIAPACA-3 CTRP1 0.2603 33.3330
ML150 A-375 CTRP1 0.2604 33.3330
ML150 HS852.T CTRP1 0.2603 33.3330
ML150 SK-MEL-1 CTRP1 0.2604 33.3330
ML150 SK-MEL-28 CTRP1 0.2604 33.3330
ML150 SK-MEL-5 CTRP1 0.2604 33.3330
ML150 HT-1080 CTRP1 0.2604 33.3330
ML150 AGS CTRP1 0.2604 33.3330
ML150 MKN74 CTRP1 0.2603 33.3330
ML150 SCC-9 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.