Drug : Sparfosic Acid

CTRP1 Name : sparfosic acid

Dataset : All
Synonyms :
Targets : CAD
Pathways : inhibitor of aspartate transcarbamylase

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
sparfosic acid MCF-7 CTRP1 2.0833 266.6700
sparfosic acid GAMG CTRP1 0.2603 33.3330
sparfosic acid LN-229 CTRP1 2.0833 266.6700
sparfosic acid SF295 CTRP1 0.2603 33.3330
sparfosic acid HEC-108 CTRP1 0.2603 33.3330
sparfosic acid HEC-151 CTRP1 2.0833 266.6700
sparfosic acid HEC-251 CTRP1 0.2603 33.3330
sparfosic acid HEC-265 CTRP1 0.2603 33.3330
sparfosic acid HEC-59 CTRP1 0.2603 33.3330
sparfosic acid HEC-6 CTRP1 0.2603 33.3330
sparfosic acid ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
sparfosic acid JHUEM-2 CTRP1 2.0833 266.6700
sparfosic acid KLE CTRP1 0.2603 33.3330
sparfosic acid MFE-319 CTRP1 0.2603 33.3330
sparfosic acid SNG-M CTRP1 0.2603 33.3330
sparfosic acid AMO1 CTRP1 2.0833 266.6700
sparfosic acid BL-70 CTRP1 0.2603 33.3330
sparfosic acid EJM CTRP1 2.0833 266.6700
sparfosic acid GDM-1 CTRP1 2.0833 266.6700
sparfosic acid HT CTRP1 0.2603 33.3330
sparfosic acid KMS-11 CTRP1 2.0833 266.6700
sparfosic acid KU812 CTRP1 0.2603 33.3330
sparfosic acid LP-1 CTRP1 2.0833 266.6700
sparfosic acid MC116 CTRP1 0.2603 33.3330
sparfosic acid MOLM-16 CTRP1 2.0833 266.6700
sparfosic acid NOMO-1 CTRP1 2.0833 266.6700
sparfosic acid NU-DUL-1 CTRP1 2.0833 266.6700
sparfosic acid OCI-AML-3 CTRP1 2.0833 266.6700
sparfosic acid OCI-LY10 CTRP1 2.0833 266.6700
sparfosic acid P3HR-1 CTRP1 0.2603 33.3330
sparfosic acid PL21 CTRP1 2.0833 266.6700
sparfosic acid RPMI-8226 CTRP1 2.0833 266.6700
sparfosic acid SKM-1 CTRP1 2.0833 266.6700
sparfosic acid SU-DHL-4 CTRP1 2.0833 266.6700
sparfosic acid SU-DHL-5 CTRP1 2.0833 266.6700
sparfosic acid THP-1 CTRP1 2.0833 266.6700
sparfosic acid U-937 CTRP1 2.0833 266.6700
sparfosic acid WSU-DLCL2 CTRP1 2.0833 266.6700
sparfosic acid RCC10RGB CTRP1 2.0833 266.6700
sparfosic acid VMRC-RCW CTRP1 0.2603 33.3330
sparfosic acid C2BBE1 CTRP1 0.2603 33.3330
sparfosic acid CL-34 CTRP1 2.0833 266.6700
sparfosic acid CL-40 CTRP1 2.0833 266.6700
sparfosic acid COLO205 CTRP1 0.2603 33.3330
sparfosic acid COLO320 CTRP1 2.0833 266.6700
sparfosic acid COLO678 CTRP1 2.0833 266.6700
sparfosic acid CW-2 CTRP1 2.0833 266.6700
sparfosic acid DLD-1 CTRP1 0.2603 33.3330
sparfosic acid GP2D CTRP1 0.2603 33.3330
sparfosic acid HCT116 CTRP1 2.0833 266.6700
sparfosic acid HCT8 CTRP1 2.0833 266.6700
sparfosic acid HT115 CTRP1 2.0833 266.6700
sparfosic acid HT-29 CTRP1 2.0833 266.6700
sparfosic acid HT-55 CTRP1 2.0833 266.6700
sparfosic acid KM12 CTRP1 2.0833 266.6700
sparfosic acid LOVO CTRP1 2.0833 266.6700
sparfosic acid LS123 CTRP1 2.0833 266.6700
sparfosic acid LS180 CTRP1 2.0833 266.6700
sparfosic acid LS411N CTRP1 0.2603 33.3330
sparfosic acid LS513 CTRP1 0.2603 33.3330
sparfosic acid MDST8 CTRP1 2.0833 266.6700
sparfosic acid NCI-H508 CTRP1 2.0833 266.6700
sparfosic acid RCM-1[HUMANESC] CTRP1 2.0833 266.6700
sparfosic acid RKO CTRP1 2.0833 266.6700
sparfosic acid SK-CO-1 CTRP1 0.2603 33.3330
sparfosic acid SNU-1040 CTRP1 2.0833 266.6700
sparfosic acid SNU-175 CTRP1 2.0833 266.6700
sparfosic acid SNU-61 CTRP1 2.0833 266.6700
sparfosic acid SNU-81 CTRP1 2.0833 266.6700
sparfosic acid SNU-C2A CTRP1 0.2603 33.3330
sparfosic acid SNU-C4 CTRP1 2.0833 266.6700
sparfosic acid SNU-C5 CTRP1 2.0833 266.6700
sparfosic acid SW403 CTRP1 0.2603 33.3330
sparfosic acid SW48 CTRP1 0.2603 33.3330
sparfosic acid SW480 CTRP1 2.0833 266.6700
sparfosic acid SW620 CTRP1 2.0833 266.6700
sparfosic acid SW948 CTRP1 2.0833 266.6700
sparfosic acid HEP-G2 CTRP1 2.0833 266.6700
sparfosic acid JHH-6 CTRP1 0.2603 33.3330
sparfosic acid SNU-398 CTRP1 2.0833 266.6700
sparfosic acid SNU-449 CTRP1 0.2603 33.3330
sparfosic acid A-549 CTRP1 0.2603 33.3330
sparfosic acid BEN CTRP1 0.2603 33.3330
sparfosic acid CAL-12T CTRP1 2.0833 266.6700
sparfosic acid CALU-3 CTRP1 0.2603 33.3330
sparfosic acid CALU-6 CTRP1 0.2603 33.3330
sparfosic acid CHAGO-K-1 CTRP1 0.2603 33.3330
sparfosic acid COLO668 CTRP1 0.2603 33.3330
sparfosic acid COLO699 CTRP1 2.0833 266.6700
sparfosic acid COR-L23 CTRP1 2.0833 266.6700
sparfosic acid COR-L279 CTRP1 0.2603 33.3330
sparfosic acid COR-L51 CTRP1 2.0833 266.6700
sparfosic acid COR-L88 CTRP1 0.2603 33.3330
sparfosic acid DMS273 CTRP1 0.2603 33.3330
sparfosic acid DV-90 CTRP1 0.2603 33.3330
sparfosic acid EBC-1 CTRP1 0.2603 33.3330
sparfosic acid EPLC-272H CTRP1 0.2603 33.3330
sparfosic acid HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
sparfosic acid HCC1195 CTRP1 2.0833 266.6700
sparfosic acid HCC1359 CTRP1 2.0833 266.6700
sparfosic acid HCC15 CTRP1 2.0833 266.6700
sparfosic acid HCC1833 CTRP1 2.0833 266.6700
sparfosic acid HCC2108 CTRP1 2.0833 266.6700
sparfosic acid HCC2935 CTRP1 2.0833 266.6700
sparfosic acid HCC33 CTRP1 0.2603 33.3330
sparfosic acid HCC4006 CTRP1 2.0833 266.6700
sparfosic acid HCC44 CTRP1 0.2603 33.3330
sparfosic acid HCC78 CTRP1 0.2603 33.3330
sparfosic acid HCC827 CTRP1 2.0833 266.6700
sparfosic acid KNS-62 CTRP1 0.2603 33.3330
sparfosic acid LC-1-SQ-SF CTRP1 0.2603 33.3330
sparfosic acid LCLC-103H CTRP1 0.2603 33.3330
sparfosic acid LCLC-97TM1 CTRP1 0.2603 33.3330
sparfosic acid LU-65 CTRP1 0.2603 33.3330
sparfosic acid LU-99 CTRP1 0.2603 33.3330
sparfosic acid LXF289 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1048 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1105 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1299 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1355 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1373 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1435 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1437 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1568 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1573 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1666 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1694 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1755 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1781 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1792 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1793 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1836 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1876 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1915 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1930 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1944 CTRP1 0.2603 33.3330
sparfosic acid NCI-H1963 CTRP1 2.0833 266.6700
sparfosic acid NCI-H1975 CTRP1 0.2603 33.3330
sparfosic acid NCI-H2009 CTRP1 0.2603 33.3330
sparfosic acid NCI-H2023 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2029 CTRP1 0.2603 33.3330
sparfosic acid NCI-H2030 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2073 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2081 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2110 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2122 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2126 CTRP1 0.2603 33.3330
sparfosic acid NCI-H2141 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2172 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2286 CTRP1 0.2603 33.3330
sparfosic acid NCI-H23 CTRP1 0.2603 33.3330
sparfosic acid NCI-H2342 CTRP1 2.0833 266.6700
sparfosic acid NCI-H2405 CTRP1 0.2603 33.3330
sparfosic acid NCI-H3255 CTRP1 2.0833 266.6700
sparfosic acid NCI-H358 CTRP1 0.2603 33.3330
sparfosic acid NCI-H441 CTRP1 2.0833 266.6700
sparfosic acid NCI-H460 CTRP1 2.0833 266.6700
sparfosic acid NCI-H522 CTRP1 0.2603 33.3330
sparfosic acid NCI-H596 CTRP1 2.0833 266.6700
sparfosic acid NCI-H650 CTRP1 0.2603 33.3330
sparfosic acid NCI-H661 CTRP1 0.2603 33.3330
sparfosic acid NCI-H727 CTRP1 0.2603 33.3330
sparfosic acid NCI-H810 CTRP1 0.2603 33.3330
sparfosic acid NCI-H82 CTRP1 0.2603 33.3330
sparfosic acid NCI-H841 CTRP1 2.0833 266.6700
sparfosic acid RERF-LC-KJ CTRP1 0.2603 33.3330
sparfosic acid SCLC-21H CTRP1 2.0833 266.6700
sparfosic acid SHP-77 CTRP1 0.2603 33.3330
sparfosic acid SK-LU-1 CTRP1 2.0833 266.6700
sparfosic acid SQ-1 CTRP1 2.0833 266.6700
sparfosic acid T3M-10 CTRP1 2.0833 266.6700
sparfosic acid VMRC-LCD CTRP1 0.2603 33.3330
sparfosic acid KYSE-140 CTRP1 0.2603 33.3330
sparfosic acid KYSE-410 CTRP1 0.2603 33.3330
sparfosic acid KYSE-450 CTRP1 0.2603 33.3330
sparfosic acid A2780 CTRP1 2.0833 266.6700
sparfosic acid CAOV-3 CTRP1 2.0833 266.6700
sparfosic acid COV318 CTRP1 0.2603 33.3330
sparfosic acid COV362 CTRP1 2.0833 266.6700
sparfosic acid COV434 CTRP1 2.0833 266.6700
sparfosic acid COV644 CTRP1 2.0833 266.6700
sparfosic acid EFO-21 CTRP1 0.2603 33.3330
sparfosic acid EFO-27 CTRP1 2.0833 266.6700
sparfosic acid HEYA8 CTRP1 0.2603 33.3330
sparfosic acid IGROV-1 CTRP1 2.0833 266.6700
sparfosic acid JHOC-5 CTRP1 2.0833 266.6700
sparfosic acid JHOM-1 CTRP1 2.0833 266.6700
sparfosic acid JHOS-4 CTRP1 0.2603 33.3330
sparfosic acid OAW42 CTRP1 2.0833 266.6700
sparfosic acid OV7 CTRP1 2.0833 266.6700
sparfosic acid OV-90 CTRP1 2.0833 266.6700
sparfosic acid OVCAR-4 CTRP1 2.0833 266.6700
sparfosic acid OVCAR-8 CTRP1 2.0833 266.6700
sparfosic acid OVK18 CTRP1 2.0833 266.6700
sparfosic acid OVKATE CTRP1 2.0833 266.6700
sparfosic acid OVMANA CTRP1 0.2603 33.3330
sparfosic acid RKN CTRP1 2.0833 266.6700
sparfosic acid RMG-I CTRP1 2.0833 266.6700
sparfosic acid RMUG-S CTRP1 2.0833 266.6700
sparfosic acid SK-OV-3 CTRP1 0.2603 33.3330
sparfosic acid SNU-840 CTRP1 2.0833 266.6700
sparfosic acid TYK-NU CTRP1 2.0833 266.6700
sparfosic acid CAPAN-2 CTRP1 0.2603 33.3330
sparfosic acid CFPAC-1 CTRP1 0.2603 33.3330
sparfosic acid HPAC CTRP1 0.2603 33.3330
sparfosic acid HUP-T4 CTRP1 0.2603 33.3330
sparfosic acid KP-3 CTRP1 0.2603 33.3330
sparfosic acid PANC03.27 CTRP1 0.2603 33.3330
sparfosic acid PANC10.05 CTRP1 0.2603 33.3330
sparfosic acid PATU8902 CTRP1 0.2603 33.3330
sparfosic acid QGP-1 CTRP1 0.2603 33.3330
sparfosic acid SUIT-2 CTRP1 0.2603 33.3330
sparfosic acid MSTO-211H CTRP1 0.2603 33.3330
sparfosic acid NCI-H2052 CTRP1 0.2603 33.3330
sparfosic acid NCI-H28 CTRP1 0.2603 33.3330
sparfosic acid MIAPACA-3 CTRP1 0.2603 33.3330
sparfosic acid A-375 CTRP1 2.0833 266.6700
sparfosic acid COLO741 CTRP1 0.2603 33.3330
sparfosic acid G-361 CTRP1 0.2603 33.3330
sparfosic acid HS852.T CTRP1 0.2603 33.3330
sparfosic acid HS936.T CTRP1 0.2603 33.3330
sparfosic acid HS944.T CTRP1 0.2603 33.3330
sparfosic acid SK-MEL-1 CTRP1 2.0833 266.6700
sparfosic acid SK-MEL-28 CTRP1 2.0833 266.6700
sparfosic acid SK-MEL-5 CTRP1 2.0833 266.6700
sparfosic acid G-401 CTRP1 0.2603 33.3330
sparfosic acid HT-1080 CTRP1 2.0833 266.6700
sparfosic acid AGS CTRP1 2.0833 266.6700
sparfosic acid FU97 CTRP1 0.2603 33.3330
sparfosic acid KE-97 CTRP1 0.2603 33.3330
sparfosic acid MKN7 CTRP1 0.2603 33.3330
sparfosic acid MKN74 CTRP1 0.2603 33.3330
sparfosic acid NUGC-4 CTRP1 0.2603 33.3330
sparfosic acid SH-10-TC CTRP1 0.2603 33.3330
sparfosic acid HSC-2 CTRP1 0.2603 33.3330
sparfosic acid SCC-9 CTRP1 2.0833 266.6700
sparfosic acid 5637 CTRP1 0.2603 33.3330
sparfosic acid HT-1376 CTRP1 0.2603 33.3330
sparfosic acid KMBC-2 CTRP1 0.2603 33.3330
sparfosic acid RT-4 CTRP1 0.2603 33.3330
sparfosic acid UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.