Drug : Brd4046

CTRP1 Name : BRD4046

Dataset : All
Synonyms :
Targets :
Pathways : product of diversity-oriented synthesis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD4046 MCF-7 CTRP1 0.6250 80.0000
BRD4046 LN-229 CTRP1 0.6250 80.0000
BRD4046 HEC-151 CTRP1 0.6250 80.0000
BRD4046 JHUEM-2 CTRP1 0.6250 80.0000
BRD4046 AMO1 CTRP1 0.6250 80.0000
BRD4046 EJM CTRP1 0.6250 80.0000
BRD4046 GDM-1 CTRP1 0.6250 80.0000
BRD4046 KMS-11 CTRP1 0.6250 80.0000
BRD4046 LP-1 CTRP1 0.6250 80.0000
BRD4046 MOLM-16 CTRP1 0.6250 80.0000
BRD4046 NOMO-1 CTRP1 0.6250 80.0000
BRD4046 NU-DUL-1 CTRP1 0.6250 80.0000
BRD4046 OCI-AML-3 CTRP1 0.6250 80.0000
BRD4046 OCI-LY10 CTRP1 0.6250 80.0000
BRD4046 PL21 CTRP1 0.6250 80.0000
BRD4046 RPMI-8226 CTRP1 0.6250 80.0000
BRD4046 SKM-1 CTRP1 0.6250 80.0000
BRD4046 SU-DHL-4 CTRP1 0.6250 80.0000
BRD4046 SU-DHL-5 CTRP1 0.6250 80.0000
BRD4046 THP-1 CTRP1 0.6250 80.0000
BRD4046 U-937 CTRP1 0.6250 80.0000
BRD4046 WSU-DLCL2 CTRP1 0.6250 80.0000
BRD4046 RCC10RGB CTRP1 0.6250 80.0000
BRD4046 CL-34 CTRP1 0.6250 80.0000
BRD4046 CL-40 CTRP1 0.6250 80.0000
BRD4046 COLO320 CTRP1 0.6250 80.0000
BRD4046 COLO678 CTRP1 0.6250 80.0000
BRD4046 CW-2 CTRP1 0.6250 80.0000
BRD4046 HCT116 CTRP1 0.6250 80.0000
BRD4046 HCT8 CTRP1 0.6250 80.0000
BRD4046 HT115 CTRP1 0.6250 80.0000
BRD4046 HT-29 CTRP1 0.6250 80.0000
BRD4046 HT-55 CTRP1 0.6250 80.0000
BRD4046 KM12 CTRP1 0.6250 80.0000
BRD4046 LOVO CTRP1 0.6250 80.0000
BRD4046 LS123 CTRP1 0.6250 80.0000
BRD4046 LS180 CTRP1 0.6250 80.0000
BRD4046 MDST8 CTRP1 0.6250 80.0000
BRD4046 NCI-H508 CTRP1 0.6250 80.0000
BRD4046 RCM-1[HUMANESC] CTRP1 0.6250 80.0000
BRD4046 RKO CTRP1 0.6250 80.0000
BRD4046 SNU-1040 CTRP1 0.6250 80.0000
BRD4046 SNU-175 CTRP1 0.6250 80.0000
BRD4046 SNU-61 CTRP1 0.6250 80.0000
BRD4046 SNU-81 CTRP1 0.6250 80.0000
BRD4046 SNU-C4 CTRP1 0.6250 80.0000
BRD4046 SNU-C5 CTRP1 0.6250 80.0000
BRD4046 SW480 CTRP1 0.6250 80.0000
BRD4046 SW620 CTRP1 0.6250 80.0000
BRD4046 SW948 CTRP1 0.6250 80.0000
BRD4046 HEP-G2 CTRP1 0.6250 80.0000
BRD4046 SNU-398 CTRP1 0.6250 80.0000
BRD4046 CAL-12T CTRP1 0.6250 80.0000
BRD4046 COLO699 CTRP1 0.6250 80.0000
BRD4046 COR-L23 CTRP1 0.6250 80.0000
BRD4046 COR-L51 CTRP1 0.6250 80.0000
BRD4046 HCC1195 CTRP1 0.6250 80.0000
BRD4046 HCC1359 CTRP1 0.6250 80.0000
BRD4046 HCC15 CTRP1 0.6250 80.0000
BRD4046 HCC1833 CTRP1 0.6250 80.0000
BRD4046 HCC2108 CTRP1 0.6250 80.0000
BRD4046 HCC2935 CTRP1 0.6250 80.0000
BRD4046 HCC4006 CTRP1 0.6250 80.0000
BRD4046 HCC827 CTRP1 0.6250 80.0000
BRD4046 NCI-H1105 CTRP1 0.6250 80.0000
BRD4046 NCI-H1694 CTRP1 0.6250 80.0000
BRD4046 NCI-H1755 CTRP1 0.6250 80.0000
BRD4046 NCI-H1781 CTRP1 0.6250 80.0000
BRD4046 NCI-H1836 CTRP1 0.6250 80.0000
BRD4046 NCI-H1876 CTRP1 0.6250 80.0000
BRD4046 NCI-H1963 CTRP1 0.6250 80.0000
BRD4046 NCI-H2023 CTRP1 0.6250 80.0000
BRD4046 NCI-H2030 CTRP1 0.6250 80.0000
BRD4046 NCI-H2073 CTRP1 0.6250 80.0000
BRD4046 NCI-H2081 CTRP1 0.6250 80.0000
BRD4046 NCI-H2110 CTRP1 0.6250 80.0000
BRD4046 NCI-H2122 CTRP1 0.6250 80.0000
BRD4046 NCI-H2141 CTRP1 0.6250 80.0000
BRD4046 NCI-H2172 CTRP1 0.6250 80.0000
BRD4046 NCI-H2342 CTRP1 0.6250 80.0000
BRD4046 NCI-H3255 CTRP1 0.6250 80.0000
BRD4046 NCI-H441 CTRP1 0.6250 80.0000
BRD4046 NCI-H460 CTRP1 0.6250 80.0000
BRD4046 NCI-H596 CTRP1 0.6250 80.0000
BRD4046 NCI-H841 CTRP1 0.6250 80.0000
BRD4046 SCLC-21H CTRP1 0.6250 80.0000
BRD4046 SK-LU-1 CTRP1 0.6250 80.0000
BRD4046 SQ-1 CTRP1 0.6250 80.0000
BRD4046 T3M-10 CTRP1 0.6250 80.0000
BRD4046 A2780 CTRP1 0.6250 80.0000
BRD4046 CAOV-3 CTRP1 0.6250 80.0000
BRD4046 COV362 CTRP1 0.6250 80.0000
BRD4046 COV434 CTRP1 0.6250 80.0000
BRD4046 COV644 CTRP1 0.6250 80.0000
BRD4046 EFO-27 CTRP1 0.6250 80.0000
BRD4046 IGROV-1 CTRP1 0.6250 80.0000
BRD4046 JHOC-5 CTRP1 0.6250 80.0000
BRD4046 JHOM-1 CTRP1 0.6250 80.0000
BRD4046 OAW42 CTRP1 0.6250 80.0000
BRD4046 OV7 CTRP1 0.6250 80.0000
BRD4046 OV-90 CTRP1 0.6250 80.0000
BRD4046 OVCAR-4 CTRP1 0.6250 80.0000
BRD4046 OVCAR-8 CTRP1 0.6250 80.0000
BRD4046 OVK18 CTRP1 0.6250 80.0000
BRD4046 OVKATE CTRP1 0.6250 80.0000
BRD4046 RKN CTRP1 0.6250 80.0000
BRD4046 RMG-I CTRP1 0.6250 80.0000
BRD4046 RMUG-S CTRP1 0.6250 80.0000
BRD4046 SNU-840 CTRP1 0.6250 80.0000
BRD4046 TYK-NU CTRP1 0.6250 80.0000
BRD4046 A-375 CTRP1 0.6250 80.0000
BRD4046 SK-MEL-1 CTRP1 0.6250 80.0000
BRD4046 SK-MEL-28 CTRP1 0.6250 80.0000
BRD4046 SK-MEL-5 CTRP1 0.6250 80.0000
BRD4046 HT-1080 CTRP1 0.6250 80.0000
BRD4046 AGS CTRP1 0.6250 80.0000
BRD4046 SCC-9 CTRP1 0.6250 80.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.