Drug : Nifedipine

CTRP1 Name : nifedipine

Dataset : All
Synonyms :
Targets : CACNA1C;CACNA1D;CACNA1S;CACNA1F
Pathways : inhibitor of L-type calcium channel

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
nifedipine U2OS CTRP1 0.2604 33.3330
nifedipine MCF-7 CTRP1 0.2604 33.3330
nifedipine GAMG CTRP1 0.2603 33.3330
nifedipine LN-229 CTRP1 0.2604 33.3330
nifedipine SF295 CTRP1 0.2603 33.3330
nifedipine HEC-108 CTRP1 0.2603 33.3330
nifedipine HEC-151 CTRP1 0.2604 33.3330
nifedipine HEC-251 CTRP1 0.2603 33.3330
nifedipine HEC-265 CTRP1 0.2603 33.3330
nifedipine HEC-59 CTRP1 0.2603 33.3330
nifedipine HEC-6 CTRP1 0.2603 33.3330
nifedipine ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
nifedipine JHUEM-2 CTRP1 0.2604 33.3330
nifedipine KLE CTRP1 0.2603 33.3330
nifedipine MFE-319 CTRP1 0.2603 33.3330
nifedipine SNG-M CTRP1 0.2603 33.3330
nifedipine AMO1 CTRP1 0.2604 33.3330
nifedipine BL-70 CTRP1 0.2603 33.3330
nifedipine EJM CTRP1 0.2604 33.3330
nifedipine GDM-1 CTRP1 0.2604 33.3330
nifedipine HT CTRP1 0.2603 33.3330
nifedipine KMS-11 CTRP1 0.2604 33.3330
nifedipine KU812 CTRP1 0.2603 33.3330
nifedipine LP-1 CTRP1 0.2604 33.3330
nifedipine MC116 CTRP1 0.2603 33.3330
nifedipine MOLM-16 CTRP1 0.2604 33.3330
nifedipine NOMO-1 CTRP1 0.2604 33.3330
nifedipine NU-DUL-1 CTRP1 0.2604 33.3330
nifedipine OCI-AML-3 CTRP1 0.2604 33.3330
nifedipine OCI-LY10 CTRP1 0.2604 33.3330
nifedipine P3HR-1 CTRP1 0.2603 33.3330
nifedipine PL21 CTRP1 0.2604 33.3330
nifedipine RPMI-8226 CTRP1 0.2604 33.3330
nifedipine SKM-1 CTRP1 0.2604 33.3330
nifedipine SU-DHL-4 CTRP1 0.2604 33.3330
nifedipine SU-DHL-5 CTRP1 0.2604 33.3330
nifedipine THP-1 CTRP1 0.2604 33.3330
nifedipine U-937 CTRP1 0.2604 33.3330
nifedipine WSU-DLCL2 CTRP1 0.2604 33.3330
nifedipine RCC10RGB CTRP1 0.2604 33.3330
nifedipine VMRC-RCW CTRP1 0.2603 33.3330
nifedipine C2BBE1 CTRP1 0.2603 33.3330
nifedipine CL-34 CTRP1 0.2604 33.3330
nifedipine CL-40 CTRP1 0.2604 33.3330
nifedipine COLO205 CTRP1 0.2603 33.3330
nifedipine COLO320 CTRP1 0.2604 16.6670
nifedipine COLO678 CTRP1 0.2604 33.3330
nifedipine CW-2 CTRP1 0.2604 33.3330
nifedipine DLD-1 CTRP1 0.2603 33.3330
nifedipine GP2D CTRP1 0.2603 33.3330
nifedipine HCT116 CTRP1 0.2604 33.3330
nifedipine HCT8 CTRP1 0.2604 33.3330
nifedipine HT115 CTRP1 0.2604 33.3330
nifedipine HT-29 CTRP1 0.2604 33.3330
nifedipine HT-55 CTRP1 0.2604 33.3330
nifedipine KM12 CTRP1 0.2604 33.3330
nifedipine LOVO CTRP1 0.2604 33.3330
nifedipine LS123 CTRP1 0.2604 33.3330
nifedipine LS180 CTRP1 0.2604 33.3330
nifedipine LS411N CTRP1 0.2603 33.3330
nifedipine LS513 CTRP1 0.2603 33.3330
nifedipine MDST8 CTRP1 0.2604 33.3330
nifedipine NCI-H508 CTRP1 0.2604 33.3330
nifedipine RCM-1[HUMANESC] CTRP1 0.2604 33.3330
nifedipine RKO CTRP1 0.2604 33.3330
nifedipine SK-CO-1 CTRP1 0.2603 33.3330
nifedipine SNU-1040 CTRP1 0.2604 33.3330
nifedipine SNU-175 CTRP1 0.2604 33.3330
nifedipine SNU-61 CTRP1 0.2604 33.3330
nifedipine SNU-81 CTRP1 0.2604 33.3330
nifedipine SNU-C2A CTRP1 0.2603 33.3330
nifedipine SNU-C4 CTRP1 0.2604 33.3330
nifedipine SNU-C5 CTRP1 0.2604 33.3330
nifedipine SW403 CTRP1 0.2603 33.3330
nifedipine SW48 CTRP1 0.2603 33.3330
nifedipine SW480 CTRP1 0.2604 33.3330
nifedipine SW620 CTRP1 0.2604 33.3330
nifedipine SW948 CTRP1 0.2604 33.3330
nifedipine HEP-G2 CTRP1 0.2604 33.3330
nifedipine JHH-6 CTRP1 0.2603 33.3330
nifedipine SNU-398 CTRP1 0.2604 33.3330
nifedipine SNU-449 CTRP1 0.2603 33.3330
nifedipine A-549 CTRP1 0.2603 33.3330
nifedipine BEN CTRP1 0.2603 33.3330
nifedipine CAL-12T CTRP1 0.2604 33.3330
nifedipine CALU-3 CTRP1 0.2603 33.3330
nifedipine CALU-6 CTRP1 0.2603 33.3330
nifedipine CHAGO-K-1 CTRP1 0.2603 33.3330
nifedipine COLO668 CTRP1 0.2603 33.3330
nifedipine COLO699 CTRP1 0.2604 33.3330
nifedipine COR-L23 CTRP1 0.2604 33.3330
nifedipine COR-L279 CTRP1 0.2603 33.3330
nifedipine COR-L51 CTRP1 0.2604 33.3330
nifedipine COR-L88 CTRP1 0.2603 33.3330
nifedipine DMS273 CTRP1 0.2603 33.3330
nifedipine DV-90 CTRP1 0.2603 33.3330
nifedipine EBC-1 CTRP1 0.2603 33.3330
nifedipine EPLC-272H CTRP1 0.2603 33.3330
nifedipine HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
nifedipine HCC1195 CTRP1 0.2604 33.3330
nifedipine HCC1359 CTRP1 0.2604 33.3330
nifedipine HCC15 CTRP1 0.2604 33.3330
nifedipine HCC1833 CTRP1 0.2604 33.3330
nifedipine HCC2108 CTRP1 0.2604 33.3330
nifedipine HCC2935 CTRP1 0.2604 33.3330
nifedipine HCC33 CTRP1 0.2603 33.3330
nifedipine HCC4006 CTRP1 0.2604 33.3330
nifedipine HCC44 CTRP1 0.2603 33.3330
nifedipine HCC78 CTRP1 0.2603 33.3330
nifedipine HCC827 CTRP1 0.2604 33.3330
nifedipine KNS-62 CTRP1 0.2603 33.3330
nifedipine LC-1-SQ-SF CTRP1 0.2603 33.3330
nifedipine LCLC-103H CTRP1 0.2603 33.3330
nifedipine LCLC-97TM1 CTRP1 0.2603 33.3330
nifedipine LU-65 CTRP1 0.2603 33.3330
nifedipine LU-99 CTRP1 0.2603 33.3330
nifedipine LXF289 CTRP1 0.2603 33.3330
nifedipine NCI-H1048 CTRP1 0.2603 33.3330
nifedipine NCI-H1105 CTRP1 0.2604 33.3330
nifedipine NCI-H1299 CTRP1 0.2603 33.3330
nifedipine NCI-H1355 CTRP1 0.2603 33.3330
nifedipine NCI-H1373 CTRP1 0.2603 33.3330
nifedipine NCI-H1435 CTRP1 0.2603 33.3330
nifedipine NCI-H1437 CTRP1 0.2603 33.3330
nifedipine NCI-H1568 CTRP1 0.2603 33.3330
nifedipine NCI-H1573 CTRP1 0.2603 33.3330
nifedipine NCI-H1666 CTRP1 0.2603 33.3330
nifedipine NCI-H1694 CTRP1 0.2604 33.3330
nifedipine NCI-H1755 CTRP1 0.2604 33.3330
nifedipine NCI-H1781 CTRP1 0.2604 33.3330
nifedipine NCI-H1792 CTRP1 0.2603 33.3330
nifedipine NCI-H1793 CTRP1 0.2603 33.3330
nifedipine NCI-H1836 CTRP1 0.2604 33.3330
nifedipine NCI-H1876 CTRP1 0.2604 33.3330
nifedipine NCI-H1915 CTRP1 0.2603 33.3330
nifedipine NCI-H1930 CTRP1 0.2603 33.3330
nifedipine NCI-H1944 CTRP1 0.2603 33.3330
nifedipine NCI-H1963 CTRP1 0.2604 33.3330
nifedipine NCI-H1975 CTRP1 0.2603 33.3330
nifedipine NCI-H2009 CTRP1 0.2603 33.3330
nifedipine NCI-H2023 CTRP1 0.2604 33.3330
nifedipine NCI-H2029 CTRP1 0.2603 33.3330
nifedipine NCI-H2030 CTRP1 0.2604 33.3330
nifedipine NCI-H2073 CTRP1 0.2604 33.3330
nifedipine NCI-H2081 CTRP1 0.2604 33.3330
nifedipine NCI-H2110 CTRP1 0.2604 33.3330
nifedipine NCI-H2122 CTRP1 0.2604 33.3330
nifedipine NCI-H2126 CTRP1 0.2603 33.3330
nifedipine NCI-H2141 CTRP1 0.2604 33.3330
nifedipine NCI-H2172 CTRP1 0.2604 33.3330
nifedipine NCI-H2286 CTRP1 0.2603 33.3330
nifedipine NCI-H23 CTRP1 0.2603 33.3330
nifedipine NCI-H2342 CTRP1 0.2604 33.3330
nifedipine NCI-H2405 CTRP1 0.2603 33.3330
nifedipine NCI-H3255 CTRP1 0.2604 33.3330
nifedipine NCI-H358 CTRP1 0.2603 33.3330
nifedipine NCI-H441 CTRP1 0.2604 33.3330
nifedipine NCI-H460 CTRP1 0.2604 33.3330
nifedipine NCI-H522 CTRP1 0.2603 33.3330
nifedipine NCI-H596 CTRP1 0.2604 33.3330
nifedipine NCI-H650 CTRP1 0.2603 33.3330
nifedipine NCI-H661 CTRP1 0.2603 33.3330
nifedipine NCI-H727 CTRP1 0.2603 33.3330
nifedipine NCI-H810 CTRP1 0.2603 33.3330
nifedipine NCI-H82 CTRP1 0.2603 33.3330
nifedipine NCI-H841 CTRP1 0.2604 33.3330
nifedipine RERF-LC-KJ CTRP1 0.2603 33.3330
nifedipine SCLC-21H CTRP1 0.2604 33.3330
nifedipine SHP-77 CTRP1 0.2603 33.3330
nifedipine SK-LU-1 CTRP1 0.2604 33.3330
nifedipine SQ-1 CTRP1 0.2604 33.3330
nifedipine T3M-10 CTRP1 0.2604 33.3330
nifedipine VMRC-LCD CTRP1 0.2603 33.3330
nifedipine KYSE-140 CTRP1 0.2603 33.3330
nifedipine KYSE-410 CTRP1 0.2603 33.3330
nifedipine KYSE-450 CTRP1 0.2603 33.3330
nifedipine A2780 CTRP1 0.2604 33.3330
nifedipine CAOV-3 CTRP1 0.2604 33.3330
nifedipine COV318 CTRP1 0.2603 33.3330
nifedipine COV362 CTRP1 0.2604 33.3330
nifedipine COV434 CTRP1 0.2604 33.3330
nifedipine COV644 CTRP1 0.2604 33.3330
nifedipine EFO-21 CTRP1 0.2603 33.3330
nifedipine EFO-27 CTRP1 0.2604 33.3330
nifedipine HEYA8 CTRP1 0.2603 33.3330
nifedipine IGROV-1 CTRP1 0.2604 33.3330
nifedipine JHOC-5 CTRP1 0.2604 33.3330
nifedipine JHOM-1 CTRP1 0.2604 33.3330
nifedipine JHOS-4 CTRP1 0.2603 33.3330
nifedipine OAW42 CTRP1 0.2604 33.3330
nifedipine OV7 CTRP1 0.2604 33.3330
nifedipine OV-90 CTRP1 0.2604 33.3330
nifedipine OVCAR-4 CTRP1 0.2604 33.3330
nifedipine OVCAR-8 CTRP1 0.2604 33.3330
nifedipine OVK18 CTRP1 0.2604 33.3330
nifedipine OVKATE CTRP1 0.2604 33.3330
nifedipine OVMANA CTRP1 0.2603 33.3330
nifedipine RKN CTRP1 0.2604 33.3330
nifedipine RMG-I CTRP1 0.2604 33.3330
nifedipine RMUG-S CTRP1 0.2604 33.3330
nifedipine SK-OV-3 CTRP1 0.2603 33.3330
nifedipine SNU-840 CTRP1 0.2604 33.3330
nifedipine TYK-NU CTRP1 0.2604 33.3330
nifedipine CAPAN-2 CTRP1 0.2603 33.3330
nifedipine CFPAC-1 CTRP1 0.2603 33.3330
nifedipine HPAC CTRP1 0.2603 33.3330
nifedipine HUP-T4 CTRP1 0.2603 33.3330
nifedipine KP-3 CTRP1 0.2603 33.3330
nifedipine PANC03.27 CTRP1 0.2603 33.3330
nifedipine PANC10.05 CTRP1 0.2603 33.3330
nifedipine PATU8902 CTRP1 0.2603 33.3330
nifedipine QGP-1 CTRP1 0.2603 33.3330
nifedipine SUIT-2 CTRP1 0.2603 33.3330
nifedipine MSTO-211H CTRP1 0.2603 33.3330
nifedipine NCI-H2052 CTRP1 0.2603 33.3330
nifedipine NCI-H28 CTRP1 0.2603 33.3330
nifedipine MIAPACA-3 CTRP1 0.2603 33.3330
nifedipine A-375 CTRP1 0.2604 33.3330
nifedipine COLO741 CTRP1 0.2603 33.3330
nifedipine G-361 CTRP1 0.2603 33.3330
nifedipine HS852.T CTRP1 0.2603 33.3330
nifedipine HS936.T CTRP1 0.2603 33.3330
nifedipine HS944.T CTRP1 0.2603 33.3330
nifedipine SK-MEL-1 CTRP1 0.2604 33.3330
nifedipine SK-MEL-28 CTRP1 0.2604 33.3330
nifedipine SK-MEL-5 CTRP1 0.2604 33.3330
nifedipine G-401 CTRP1 0.2603 33.3330
nifedipine HT-1080 CTRP1 0.2604 33.3330
nifedipine AGS CTRP1 0.2604 33.3330
nifedipine FU97 CTRP1 0.2603 33.3330
nifedipine KE-97 CTRP1 0.2603 33.3330
nifedipine MKN7 CTRP1 0.2603 33.3330
nifedipine MKN74 CTRP1 0.2603 33.3330
nifedipine NUGC-4 CTRP1 0.2603 33.3330
nifedipine SH-10-TC CTRP1 0.2603 33.3330
nifedipine HSC-2 CTRP1 0.2603 33.3330
nifedipine SCC-9 CTRP1 0.2604 33.3330
nifedipine 5637 CTRP1 0.2603 33.3330
nifedipine HT-1376 CTRP1 0.2603 33.3330
nifedipine KMBC-2 CTRP1 0.2603 33.3330
nifedipine RT-4 CTRP1 0.2603 33.3330
nifedipine UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.