Drug : Cyt-997

CTRP1 Name : CYT-997

Dataset : All
Synonyms :
Targets :
Pathways : inhibitor of tubulin polymerization

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
CYT-997 LN-229 CTRP1 0.0260 3.3333
CYT-997 JHUEM-2 CTRP1 0.0260 3.3333
CYT-997 GDM-1 CTRP1 0.0260 3.3333
CYT-997 MOLM-16 CTRP1 0.0260 3.3333
CYT-997 NOMO-1 CTRP1 0.0260 3.3333
CYT-997 NU-DUL-1 CTRP1 0.0260 3.3333
CYT-997 OCI-AML-3 CTRP1 0.0260 3.3333
CYT-997 PL21 CTRP1 0.0260 3.3333
CYT-997 RPMI-8226 CTRP1 0.0260 3.3333
CYT-997 SKM-1 CTRP1 0.0260 3.3333
CYT-997 SU-DHL-4 CTRP1 0.0260 3.3333
CYT-997 SU-DHL-5 CTRP1 0.0260 3.3333
CYT-997 THP-1 CTRP1 0.0260 3.3333
CYT-997 U-937 CTRP1 0.0260 3.3333
CYT-997 WSU-DLCL2 CTRP1 0.0260 3.3333
CYT-997 CL-34 CTRP1 0.0260 3.3333
CYT-997 CL-40 CTRP1 0.0260 3.3333
CYT-997 COLO320 CTRP1 0.0260 3.3333
CYT-997 COLO678 CTRP1 0.0260 3.3333
CYT-997 CW-2 CTRP1 0.0260 3.3333
CYT-997 HCT116 CTRP1 0.0260 3.3333
CYT-997 HCT8 CTRP1 0.0260 3.3333
CYT-997 HT115 CTRP1 0.0260 3.3333
CYT-997 HT-29 CTRP1 0.0260 3.3333
CYT-997 HT-55 CTRP1 0.0260 3.3333
CYT-997 KM12 CTRP1 0.0260 3.3333
CYT-997 LOVO CTRP1 0.0260 3.3333
CYT-997 LS123 CTRP1 0.0260 3.3333
CYT-997 MDST8 CTRP1 0.0260 3.3333
CYT-997 NCI-H508 CTRP1 0.0260 3.3333
CYT-997 RCM-1[HUMANESC] CTRP1 0.0260 3.3333
CYT-997 RKO CTRP1 0.0260 3.3333
CYT-997 SNU-1040 CTRP1 0.0260 3.3333
CYT-997 SNU-175 CTRP1 0.0260 3.3333
CYT-997 SNU-61 CTRP1 0.0260 3.3333
CYT-997 SNU-81 CTRP1 0.0260 3.3333
CYT-997 SNU-C4 CTRP1 0.0260 3.3333
CYT-997 SNU-C5 CTRP1 0.0260 3.3333
CYT-997 SW480 CTRP1 0.0260 3.3333
CYT-997 SW620 CTRP1 0.0260 3.3333
CYT-997 SW948 CTRP1 0.0260 3.3333
CYT-997 COR-L23 CTRP1 0.0260 3.3333
CYT-997 HCC15 CTRP1 0.0260 3.3333
CYT-997 NCI-H1755 CTRP1 0.0260 3.3333
CYT-997 NCI-H1781 CTRP1 0.0260 3.3333
CYT-997 NCI-H1836 CTRP1 0.0260 3.3333
CYT-997 NCI-H2073 CTRP1 0.0260 3.3333
CYT-997 NCI-H2110 CTRP1 0.0260 3.3333
CYT-997 NCI-H2122 CTRP1 0.0260 3.3333
CYT-997 NCI-H3255 CTRP1 0.0260 3.3333
CYT-997 NCI-H441 CTRP1 0.0260 3.3333
CYT-997 NCI-H460 CTRP1 0.0260 3.3333
CYT-997 NCI-H596 CTRP1 0.0260 3.3333
CYT-997 SK-LU-1 CTRP1 0.0260 3.3333
CYT-997 T3M-10 CTRP1 0.0260 3.3333
CYT-997 CAOV-3 CTRP1 0.0260 3.3333
CYT-997 COV362 CTRP1 0.0260 3.3333
CYT-997 COV644 CTRP1 0.0260 3.3333
CYT-997 OV7 CTRP1 0.0260 3.3333
CYT-997 OV-90 CTRP1 0.0260 3.3333
CYT-997 RMG-I CTRP1 0.0260 3.3333
CYT-997 RMUG-S CTRP1 0.0260 3.3333
CYT-997 SNU-840 CTRP1 0.0260 3.3333
CYT-997 TYK-NU CTRP1 0.0260 3.3333
CYT-997 A-375 CTRP1 0.0260 3.3333
CYT-997 SK-MEL-1 CTRP1 0.0260 3.3333
CYT-997 SK-MEL-28 CTRP1 0.0260 3.3333
CYT-997 SK-MEL-5 CTRP1 0.0260 3.3333
CYT-997 HT-1080 CTRP1 0.0260 3.3333

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.