Drug : Pik-75

CTRP1 Name : PIK-75

Dataset : All
Synonyms :
Targets : PIK3CA;PIK3CG
Pathways : inhibitor of PI3K p110? and PI3K p110?

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
PIK-75 U2OS CTRP1 0.0023 0.2890
PIK-75 MCF-7 CTRP1 0.0023 0.2890
PIK-75 GAMG CTRP1 0.0030 37.0000
PIK-75 LN-229 CTRP1 0.0023 0.2890
PIK-75 SF295 CTRP1 0.2890 37.0000
PIK-75 HEC-108 CTRP1 0.0030 37.0000
PIK-75 HEC-151 CTRP1 0.0023 0.2890
PIK-75 HEC-251 CTRP1 0.2890 37.0000
PIK-75 HEC-265 CTRP1 0.2890 37.0000
PIK-75 HEC-59 CTRP1 0.0030 37.0000
PIK-75 HEC-6 CTRP1 0.2890 37.0000
PIK-75 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.0030 37.0000
PIK-75 JHUEM-2 CTRP1 0.0023 0.2890
PIK-75 KLE CTRP1 0.0030 37.0000
PIK-75 MFE-319 CTRP1 0.2890 37.0000
PIK-75 SNG-M CTRP1 0.0030 37.0000
PIK-75 AMO1 CTRP1 0.0023 0.2890
PIK-75 BL-70 CTRP1 0.0030 37.0000
PIK-75 EJM CTRP1 0.0023 0.2890
PIK-75 GDM-1 CTRP1 0.0023 0.2890
PIK-75 HT CTRP1 0.2890 37.0000
PIK-75 KMS-11 CTRP1 0.0023 0.2890
PIK-75 KU812 CTRP1 0.2890 37.0000
PIK-75 LP-1 CTRP1 0.0023 0.2890
PIK-75 MC116 CTRP1 0.2890 37.0000
PIK-75 MOLM-16 CTRP1 0.0023 0.2890
PIK-75 NOMO-1 CTRP1 0.0023 0.2890
PIK-75 NU-DUL-1 CTRP1 0.0023 0.2890
PIK-75 OCI-AML-3 CTRP1 0.0023 0.2890
PIK-75 OCI-LY10 CTRP1 0.0023 0.2890
PIK-75 P3HR-1 CTRP1 0.2890 37.0000
PIK-75 PL21 CTRP1 0.0023 0.2890
PIK-75 RPMI-8226 CTRP1 0.0023 0.2890
PIK-75 SKM-1 CTRP1 0.0023 0.2890
PIK-75 SU-DHL-4 CTRP1 0.0023 0.2890
PIK-75 SU-DHL-5 CTRP1 0.0023 0.2890
PIK-75 THP-1 CTRP1 0.0023 0.2890
PIK-75 U-937 CTRP1 0.0023 0.2890
PIK-75 WSU-DLCL2 CTRP1 0.0023 0.2890
PIK-75 RCC10RGB CTRP1 0.0023 0.2890
PIK-75 VMRC-RCW CTRP1 0.2890 37.0000
PIK-75 C2BBE1 CTRP1 0.2890 37.0000
PIK-75 CL-34 CTRP1 0.0023 0.2890
PIK-75 CL-40 CTRP1 0.0023 0.2890
PIK-75 COLO205 CTRP1 0.2890 37.0000
PIK-75 COLO320 CTRP1 0.0023 0.2890
PIK-75 COLO678 CTRP1 0.0023 0.2890
PIK-75 CW-2 CTRP1 0.0023 0.2890
PIK-75 DLD-1 CTRP1 0.2890 37.0000
PIK-75 GP2D CTRP1 0.2890 37.0000
PIK-75 HCT116 CTRP1 0.0023 0.2890
PIK-75 HCT8 CTRP1 0.0023 0.2890
PIK-75 HT115 CTRP1 0.0023 0.2890
PIK-75 HT-29 CTRP1 0.0023 0.2890
PIK-75 HT-55 CTRP1 0.0023 0.2890
PIK-75 KM12 CTRP1 0.0023 0.2890
PIK-75 LOVO CTRP1 0.0023 0.2890
PIK-75 LS123 CTRP1 0.0023 0.2890
PIK-75 LS180 CTRP1 0.0023 0.2890
PIK-75 LS411N CTRP1 0.2890 37.0000
PIK-75 LS513 CTRP1 0.2890 37.0000
PIK-75 MDST8 CTRP1 0.0023 0.2890
PIK-75 NCI-H508 CTRP1 0.0023 0.2890
PIK-75 RCM-1[HUMANESC] CTRP1 0.0023 0.2890
PIK-75 RKO CTRP1 0.0023 0.2890
PIK-75 SK-CO-1 CTRP1 0.2890 37.0000
PIK-75 SNU-1040 CTRP1 0.0023 0.2890
PIK-75 SNU-175 CTRP1 0.0023 0.2890
PIK-75 SNU-61 CTRP1 0.0023 0.2890
PIK-75 SNU-81 CTRP1 0.0023 0.2890
PIK-75 SNU-C2A CTRP1 0.2890 37.0000
PIK-75 SNU-C4 CTRP1 0.0023 0.2890
PIK-75 SNU-C5 CTRP1 0.0023 0.2890
PIK-75 SW403 CTRP1 0.2890 37.0000
PIK-75 SW48 CTRP1 0.2890 37.0000
PIK-75 SW480 CTRP1 0.0023 0.2890
PIK-75 SW620 CTRP1 0.0023 0.2890
PIK-75 SW948 CTRP1 0.0023 0.2890
PIK-75 HEP-G2 CTRP1 0.0023 0.2890
PIK-75 JHH-6 CTRP1 0.0030 37.0000
PIK-75 SNU-398 CTRP1 0.0023 0.2890
PIK-75 SNU-449 CTRP1 0.0030 37.0000
PIK-75 A-549 CTRP1 0.2890 37.0000
PIK-75 BEN CTRP1 0.2890 37.0000
PIK-75 CAL-12T CTRP1 0.0023 0.2890
PIK-75 CALU-3 CTRP1 0.2890 37.0000
PIK-75 CALU-6 CTRP1 0.2890 37.0000
PIK-75 CHAGO-K-1 CTRP1 0.2890 37.0000
PIK-75 COLO668 CTRP1 0.0030 37.0000
PIK-75 COLO699 CTRP1 0.0023 0.2890
PIK-75 COR-L23 CTRP1 0.0023 0.2890
PIK-75 COR-L279 CTRP1 0.2890 37.0000
PIK-75 COR-L51 CTRP1 0.0023 0.2890
PIK-75 COR-L88 CTRP1 0.2890 37.0000
PIK-75 DMS273 CTRP1 0.2890 37.0000
PIK-75 DV-90 CTRP1 0.2890 37.0000
PIK-75 EBC-1 CTRP1 0.2890 37.0000
PIK-75 EPLC-272H CTRP1 0.2890 37.0000
PIK-75 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2890 37.0000
PIK-75 HCC1195 CTRP1 0.0023 0.2890
PIK-75 HCC1359 CTRP1 0.0023 0.2890
PIK-75 HCC15 CTRP1 0.0023 0.2890
PIK-75 HCC1833 CTRP1 0.0023 0.2890
PIK-75 HCC2108 CTRP1 0.0023 0.2890
PIK-75 HCC2935 CTRP1 0.0023 0.2890
PIK-75 HCC33 CTRP1 0.2890 37.0000
PIK-75 HCC4006 CTRP1 0.0023 0.2890
PIK-75 HCC44 CTRP1 0.2890 37.0000
PIK-75 HCC78 CTRP1 0.2890 37.0000
PIK-75 HCC827 CTRP1 0.0023 0.2890
PIK-75 KNS-62 CTRP1 0.2890 37.0000
PIK-75 LC-1-SQ-SF CTRP1 0.2890 37.0000
PIK-75 LCLC-103H CTRP1 0.2890 37.0000
PIK-75 LCLC-97TM1 CTRP1 0.2890 37.0000
PIK-75 LU-65 CTRP1 0.2890 37.0000
PIK-75 LU-99 CTRP1 0.2890 37.0000
PIK-75 LXF289 CTRP1 0.0030 37.0000
PIK-75 NCI-H1048 CTRP1 0.2890 37.0000
PIK-75 NCI-H1105 CTRP1 0.0023 0.2890
PIK-75 NCI-H1299 CTRP1 0.2890 37.0000
PIK-75 NCI-H1355 CTRP1 0.2890 37.0000
PIK-75 NCI-H1373 CTRP1 0.2890 37.0000
PIK-75 NCI-H1435 CTRP1 0.0030 37.0000
PIK-75 NCI-H1437 CTRP1 0.2890 37.0000
PIK-75 NCI-H1568 CTRP1 0.2890 37.0000
PIK-75 NCI-H1573 CTRP1 0.2890 37.0000
PIK-75 NCI-H1666 CTRP1 0.2890 37.0000
PIK-75 NCI-H1694 CTRP1 0.0023 0.2890
PIK-75 NCI-H1755 CTRP1 0.0023 0.2890
PIK-75 NCI-H1781 CTRP1 0.0023 0.2890
PIK-75 NCI-H1792 CTRP1 0.2890 37.0000
PIK-75 NCI-H1793 CTRP1 0.2890 37.0000
PIK-75 NCI-H1836 CTRP1 0.0023 0.2890
PIK-75 NCI-H1876 CTRP1 0.0023 0.2890
PIK-75 NCI-H1915 CTRP1 0.0030 37.0000
PIK-75 NCI-H1930 CTRP1 0.0030 37.0000
PIK-75 NCI-H1944 CTRP1 0.2890 37.0000
PIK-75 NCI-H1963 CTRP1 0.0023 0.2890
PIK-75 NCI-H1975 CTRP1 0.2890 37.0000
PIK-75 NCI-H2009 CTRP1 0.2890 37.0000
PIK-75 NCI-H2023 CTRP1 0.0023 0.2890
PIK-75 NCI-H2029 CTRP1 0.2890 37.0000
PIK-75 NCI-H2030 CTRP1 0.0023 0.2890
PIK-75 NCI-H2073 CTRP1 0.0023 0.2890
PIK-75 NCI-H2081 CTRP1 0.0023 0.2890
PIK-75 NCI-H2110 CTRP1 0.0023 0.2890
PIK-75 NCI-H2122 CTRP1 0.0023 0.2890
PIK-75 NCI-H2126 CTRP1 0.2890 37.0000
PIK-75 NCI-H2141 CTRP1 0.0023 0.2890
PIK-75 NCI-H2172 CTRP1 0.0023 0.2890
PIK-75 NCI-H2286 CTRP1 0.0030 37.0000
PIK-75 NCI-H23 CTRP1 0.2890 37.0000
PIK-75 NCI-H2342 CTRP1 0.0023 0.2890
PIK-75 NCI-H2405 CTRP1 0.2890 37.0000
PIK-75 NCI-H3255 CTRP1 0.0023 0.2890
PIK-75 NCI-H358 CTRP1 0.2890 37.0000
PIK-75 NCI-H441 CTRP1 0.0023 0.2890
PIK-75 NCI-H460 CTRP1 0.0023 0.2890
PIK-75 NCI-H522 CTRP1 0.2890 37.0000
PIK-75 NCI-H596 CTRP1 0.0023 0.2890
PIK-75 NCI-H650 CTRP1 0.2890 37.0000
PIK-75 NCI-H661 CTRP1 0.2890 37.0000
PIK-75 NCI-H727 CTRP1 0.2890 37.0000
PIK-75 NCI-H810 CTRP1 0.2890 37.0000
PIK-75 NCI-H82 CTRP1 0.2890 37.0000
PIK-75 NCI-H841 CTRP1 0.0023 0.2890
PIK-75 RERF-LC-KJ CTRP1 0.0030 37.0000
PIK-75 SCLC-21H CTRP1 0.0023 0.2890
PIK-75 SHP-77 CTRP1 0.2890 37.0000
PIK-75 SK-LU-1 CTRP1 0.0023 0.2890
PIK-75 SQ-1 CTRP1 0.0023 0.2890
PIK-75 T3M-10 CTRP1 0.0023 0.2890
PIK-75 VMRC-LCD CTRP1 0.2890 37.0000
PIK-75 KYSE-140 CTRP1 0.2890 37.0000
PIK-75 KYSE-410 CTRP1 0.2890 37.0000
PIK-75 KYSE-450 CTRP1 0.2890 37.0000
PIK-75 A2780 CTRP1 0.0023 0.2890
PIK-75 CAOV-3 CTRP1 0.0023 0.2890
PIK-75 COV318 CTRP1 0.0030 37.0000
PIK-75 COV362 CTRP1 0.0023 0.2890
PIK-75 COV434 CTRP1 0.0023 0.2890
PIK-75 COV644 CTRP1 0.0023 0.2890
PIK-75 EFO-21 CTRP1 0.2890 37.0000
PIK-75 EFO-27 CTRP1 0.0023 0.2890
PIK-75 HEYA8 CTRP1 0.2890 37.0000
PIK-75 IGROV-1 CTRP1 0.0023 0.2890
PIK-75 JHOC-5 CTRP1 0.0023 0.2890
PIK-75 JHOM-1 CTRP1 0.0023 0.2890
PIK-75 JHOS-4 CTRP1 0.0030 37.0000
PIK-75 OAW42 CTRP1 0.0023 0.2890
PIK-75 OV7 CTRP1 0.0023 0.2890
PIK-75 OV-90 CTRP1 0.0023 0.2890
PIK-75 OVCAR-4 CTRP1 0.0023 0.2890
PIK-75 OVCAR-8 CTRP1 0.0023 0.2890
PIK-75 OVK18 CTRP1 0.0023 0.2890
PIK-75 OVKATE CTRP1 0.0023 0.2890
PIK-75 OVMANA CTRP1 0.0030 37.0000
PIK-75 RKN CTRP1 0.0023 0.2890
PIK-75 RMG-I CTRP1 0.0023 0.2890
PIK-75 RMUG-S CTRP1 0.0023 0.2890
PIK-75 SK-OV-3 CTRP1 0.2890 37.0000
PIK-75 SNU-840 CTRP1 0.0023 0.2890
PIK-75 TYK-NU CTRP1 0.0023 0.2890
PIK-75 CAPAN-2 CTRP1 0.2890 37.0000
PIK-75 CFPAC-1 CTRP1 0.2890 37.0000
PIK-75 HPAC CTRP1 0.2890 37.0000
PIK-75 HUP-T4 CTRP1 0.2890 37.0000
PIK-75 KP-3 CTRP1 0.2890 37.0000
PIK-75 PANC03.27 CTRP1 0.2890 37.0000
PIK-75 PANC10.05 CTRP1 0.2890 37.0000
PIK-75 PATU8902 CTRP1 0.0030 37.0000
PIK-75 QGP-1 CTRP1 0.2890 37.0000
PIK-75 SUIT-2 CTRP1 0.2890 37.0000
PIK-75 MSTO-211H CTRP1 0.2890 37.0000
PIK-75 NCI-H2052 CTRP1 0.2890 37.0000
PIK-75 NCI-H28 CTRP1 0.2890 37.0000
PIK-75 MIAPACA-3 CTRP1 0.0030 37.0000
PIK-75 A-375 CTRP1 0.0023 0.2890
PIK-75 COLO741 CTRP1 0.2890 37.0000
PIK-75 G-361 CTRP1 0.2890 37.0000
PIK-75 HS852.T CTRP1 0.0030 37.0000
PIK-75 HS936.T CTRP1 0.2890 37.0000
PIK-75 HS944.T CTRP1 0.2890 37.0000
PIK-75 SK-MEL-1 CTRP1 0.0023 0.2890
PIK-75 SK-MEL-28 CTRP1 0.0023 0.2890
PIK-75 SK-MEL-5 CTRP1 0.0023 0.2890
PIK-75 G-401 CTRP1 0.2890 37.0000
PIK-75 HT-1080 CTRP1 0.0023 0.2890
PIK-75 AGS CTRP1 0.0023 0.2890
PIK-75 FU97 CTRP1 0.2890 37.0000
PIK-75 KE-97 CTRP1 0.2890 37.0000
PIK-75 MKN7 CTRP1 0.2890 37.0000
PIK-75 MKN74 CTRP1 0.0030 37.0000
PIK-75 NUGC-4 CTRP1 0.2890 37.0000
PIK-75 SH-10-TC CTRP1 0.2890 37.0000
PIK-75 HSC-2 CTRP1 0.2890 37.0000
PIK-75 SCC-9 CTRP1 0.0023 0.2890
PIK-75 5637 CTRP1 0.2890 37.0000
PIK-75 HT-1376 CTRP1 0.2890 37.0000
PIK-75 KMBC-2 CTRP1 0.2890 37.0000
PIK-75 RT-4 CTRP1 0.2890 37.0000
PIK-75 UM-UC-3 CTRP1 0.2890 37.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.