Drug : Ubistatin B
CTRP1 Name
: ubistatin B
Dataset : All
Synonyms :
Targets :
Pathways : binds ubiquitin chains and blocks degradation of ubiquitinated substrates by proteasome
Information Cards
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Drug name | Cellosaurus ID | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| ubistatin B | U2OS | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | MCF-7 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | GAMG | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | LN-229 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SF295 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HEC-108 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HEC-151 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | HEC-251 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | HEC-265 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | HEC-59 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | HEC-6 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | ISHIKAWA(HERAKLIO)02ER- | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | JHUEM-2 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | KLE | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | MFE-319 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SNG-M | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | AMO1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | BL-70 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | EJM | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | GDM-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | HT | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KMS-11 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | KU812 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LP-1 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | MC116 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | MOLM-16 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NOMO-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NU-DUL-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OCI-AML-3 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OCI-LY10 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | P3HR-1 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | PL21 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | RPMI-8226 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SKM-1 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SU-DHL-4 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SU-DHL-5 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | THP-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | U-937 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | WSU-DLCL2 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | RCC10RGB | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | VMRC-RCW | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | C2BBE1 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | CL-34 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | CL-40 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | COLO205 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | COLO320 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | COLO678 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | CW-2 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | DLD-1 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | GP2D | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | HCT116 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCT8 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HT115 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HT-29 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HT-55 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | KM12 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | LOVO | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | LS123 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | LS180 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | LS411N | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LS513 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | MDST8 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H508 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | RCM-1[HUMANESC] | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | RKO | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SK-CO-1 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | SNU-1040 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SNU-175 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SNU-61 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SNU-81 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SNU-C2A | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | SNU-C4 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SNU-C5 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SW403 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | SW48 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | SW480 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SW620 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SW948 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HEP-G2 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | JHH-6 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | SNU-398 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | SNU-449 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | A-549 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | BEN | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | CAL-12T | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | CALU-3 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | CALU-6 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | CHAGO-K-1 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | COLO668 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | COLO699 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | COR-L23 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | COR-L279 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | COR-L51 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | COR-L88 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | DMS273 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | DV-90 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | EBC-1 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | EPLC-272H | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HCC1195 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | HCC1359 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC15 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC1833 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC2108 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC2935 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC33 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | HCC4006 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | HCC44 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HCC78 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HCC827 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | KNS-62 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LC-1-SQ-SF | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LCLC-103H | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LCLC-97TM1 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LU-65 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LU-99 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | LXF289 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H1048 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1105 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H1299 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H1355 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1373 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1435 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1437 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1568 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1573 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1666 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1694 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H1755 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H1781 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H1792 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1793 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1836 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H1876 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H1915 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H1930 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1944 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H1963 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H1975 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H2009 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H2023 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2029 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H2030 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2073 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2081 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2110 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2122 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2126 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H2141 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2172 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2286 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H23 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H2342 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H2405 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H3255 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | NCI-H358 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H441 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H460 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H522 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H596 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | NCI-H650 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H661 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H727 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H810 | CTRP1 | 0.2603 | 33.3330 |
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| ubistatin B | NCI-H82 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H841 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | RERF-LC-KJ | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SCLC-21H | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SHP-77 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SK-LU-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SQ-1 | CTRP1 | 4.1667 | 533.3300 |
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| ubistatin B | T3M-10 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | VMRC-LCD | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KYSE-140 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KYSE-410 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KYSE-450 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | A2780 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | CAOV-3 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | COV318 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | COV362 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | COV434 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | COV644 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | EFO-21 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | EFO-27 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | HEYA8 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | IGROV-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | JHOC-5 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | JHOM-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | JHOS-4 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | OAW42 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OV7 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OV-90 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OVCAR-4 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OVCAR-8 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OVK18 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OVKATE | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | OVMANA | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | RKN | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | RMG-I | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | RMUG-S | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SK-OV-3 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SNU-840 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | TYK-NU | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | CAPAN-2 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | CFPAC-1 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HPAC | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HUP-T4 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KP-3 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | PANC03.27 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | PANC10.05 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | PATU8902 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | QGP-1 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SUIT-2 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | MSTO-211H | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H2052 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NCI-H28 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | MIAPACA-3 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | A-375 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | COLO741 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | G-361 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HS852.T | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HS936.T | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HS944.T | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SK-MEL-1 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SK-MEL-28 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | SK-MEL-5 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | G-401 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HT-1080 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | AGS | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | FU97 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KE-97 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | MKN7 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | MKN74 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | NUGC-4 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SH-10-TC | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HSC-2 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | SCC-9 | CTRP1 | 4.1667 | 533.3300 |
|
| ubistatin B | 5637 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | HT-1376 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | KMBC-2 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | RT-4 | CTRP1 | 0.2603 | 33.3330 |
|
| ubistatin B | UM-UC-3 | CTRP1 | 0.2603 | 33.3330 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Cell lines with highest and lowest IC50
Cell lines with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Cell lines with highest and lowest IC90
Cell lines with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Cell lines with highest and lowest AUC
Cell lines with highest and lowest AUC
Associated Genes (Mutation)
Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from
pancan data.
Associated Genes (Gene Expression)
Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from
pancan data.