Drug : Jzl-184

CTRP1 Name : JZL-184

Dataset : All
Synonyms :
Targets : MGLL
Pathways : inhibitor of monoacylglycerol lipase (MAGL)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

:


Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
JZL-184 U2OS CTRP1 0.2891 37.0000
JZL-184 MCF-7 CTRP1 0.2891 37.0000
JZL-184 GAMG CTRP1 0.2890 37.0000
JZL-184 LN-229 CTRP1 0.2891 37.0000
JZL-184 SF295 CTRP1 0.2890 37.0000
JZL-184 HEC-108 CTRP1 0.2890 37.0000
JZL-184 HEC-151 CTRP1 0.2891 37.0000
JZL-184 HEC-251 CTRP1 0.2890 37.0000
JZL-184 HEC-265 CTRP1 0.2890 37.0000
JZL-184 HEC-59 CTRP1 0.2890 37.0000
JZL-184 HEC-6 CTRP1 0.2890 37.0000
JZL-184 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2890 37.0000
JZL-184 JHUEM-2 CTRP1 0.2891 37.0000
JZL-184 KLE CTRP1 0.2890 37.0000
JZL-184 MFE-319 CTRP1 0.2890 37.0000
JZL-184 SNG-M CTRP1 0.2890 37.0000
JZL-184 AMO1 CTRP1 0.2891 37.0000
JZL-184 BL-70 CTRP1 0.2890 37.0000
JZL-184 EJM CTRP1 0.2891 37.0000
JZL-184 GDM-1 CTRP1 0.2891 37.0000
JZL-184 HT CTRP1 0.2890 37.0000
JZL-184 KMS-11 CTRP1 0.2891 37.0000
JZL-184 KU812 CTRP1 0.2890 37.0000
JZL-184 LP-1 CTRP1 0.2891 37.0000
JZL-184 MC116 CTRP1 0.2890 37.0000
JZL-184 MOLM-16 CTRP1 0.2891 37.0000
JZL-184 NOMO-1 CTRP1 0.2891 37.0000
JZL-184 NU-DUL-1 CTRP1 0.2891 37.0000
JZL-184 OCI-AML-3 CTRP1 0.2891 37.0000
JZL-184 OCI-LY10 CTRP1 0.2891 37.0000
JZL-184 P3HR-1 CTRP1 0.2890 37.0000
JZL-184 PL21 CTRP1 0.2891 37.0000
JZL-184 RPMI-8226 CTRP1 0.2891 37.0000
JZL-184 SKM-1 CTRP1 0.2891 37.0000
JZL-184 SU-DHL-4 CTRP1 0.2891 37.0000
JZL-184 SU-DHL-5 CTRP1 0.2891 37.0000
JZL-184 THP-1 CTRP1 0.2891 37.0000
JZL-184 U-937 CTRP1 0.2891 37.0000
JZL-184 WSU-DLCL2 CTRP1 0.2891 37.0000
JZL-184 RCC10RGB CTRP1 0.2891 37.0000
JZL-184 VMRC-RCW CTRP1 0.2890 37.0000
JZL-184 C2BBE1 CTRP1 0.2890 37.0000
JZL-184 CL-34 CTRP1 0.2891 37.0000
JZL-184 CL-40 CTRP1 0.2891 37.0000
JZL-184 COLO205 CTRP1 0.2890 37.0000
JZL-184 COLO320 CTRP1 0.2891 37.0000
JZL-184 COLO678 CTRP1 0.2891 37.0000
JZL-184 CW-2 CTRP1 0.2891 37.0000
JZL-184 DLD-1 CTRP1 0.2890 37.0000
JZL-184 GP2D CTRP1 0.2890 37.0000
JZL-184 HCT116 CTRP1 0.2891 37.0000
JZL-184 HCT8 CTRP1 0.2891 37.0000
JZL-184 HT115 CTRP1 0.2891 37.0000
JZL-184 HT-29 CTRP1 0.2891 37.0000
JZL-184 HT-55 CTRP1 0.2891 37.0000
JZL-184 KM12 CTRP1 0.2891 37.0000
JZL-184 LOVO CTRP1 0.2891 37.0000
JZL-184 LS123 CTRP1 0.2891 37.0000
JZL-184 LS180 CTRP1 0.2891 37.0000
JZL-184 LS411N CTRP1 0.2890 37.0000
JZL-184 LS513 CTRP1 0.2890 37.0000
JZL-184 MDST8 CTRP1 0.2891 37.0000
JZL-184 NCI-H508 CTRP1 0.2891 37.0000
JZL-184 RCM-1[HUMANESC] CTRP1 0.2891 37.0000
JZL-184 RKO CTRP1 0.2891 37.0000
JZL-184 SK-CO-1 CTRP1 0.2890 37.0000
JZL-184 SNU-1040 CTRP1 0.2891 37.0000
JZL-184 SNU-175 CTRP1 0.2891 37.0000
JZL-184 SNU-61 CTRP1 0.2891 37.0000
JZL-184 SNU-81 CTRP1 0.2891 37.0000
JZL-184 SNU-C2A CTRP1 0.2890 37.0000
JZL-184 SNU-C4 CTRP1 0.2891 37.0000
JZL-184 SNU-C5 CTRP1 0.2891 37.0000
JZL-184 SW403 CTRP1 0.2890 37.0000
JZL-184 SW48 CTRP1 0.2890 37.0000
JZL-184 SW480 CTRP1 0.2891 37.0000
JZL-184 SW620 CTRP1 0.2891 37.0000
JZL-184 SW948 CTRP1 0.2891 37.0000
JZL-184 HEP-G2 CTRP1 0.2891 37.0000
JZL-184 JHH-6 CTRP1 0.2890 37.0000
JZL-184 SNU-398 CTRP1 0.2891 37.0000
JZL-184 SNU-449 CTRP1 0.2890 37.0000
JZL-184 A-549 CTRP1 0.2890 37.0000
JZL-184 BEN CTRP1 0.2890 37.0000
JZL-184 CAL-12T CTRP1 0.2891 37.0000
JZL-184 CALU-3 CTRP1 0.2890 37.0000
JZL-184 CALU-6 CTRP1 0.2890 37.0000
JZL-184 CHAGO-K-1 CTRP1 0.2890 37.0000
JZL-184 COLO668 CTRP1 0.2890 37.0000
JZL-184 COLO699 CTRP1 0.2891 37.0000
JZL-184 COR-L23 CTRP1 0.2891 37.0000
JZL-184 COR-L279 CTRP1 0.2890 37.0000
JZL-184 COR-L51 CTRP1 0.2891 37.0000
JZL-184 COR-L88 CTRP1 0.2890 37.0000
JZL-184 DMS273 CTRP1 0.2890 37.0000
JZL-184 DV-90 CTRP1 0.2890 37.0000
JZL-184 EBC-1 CTRP1 0.2890 37.0000
JZL-184 EPLC-272H CTRP1 0.2890 37.0000
JZL-184 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2890 37.0000
JZL-184 HCC1195 CTRP1 0.2891 37.0000
JZL-184 HCC1359 CTRP1 0.2891 37.0000
JZL-184 HCC15 CTRP1 0.2891 37.0000
JZL-184 HCC1833 CTRP1 0.2891 37.0000
JZL-184 HCC2108 CTRP1 0.2891 37.0000
JZL-184 HCC2935 CTRP1 0.2891 37.0000
JZL-184 HCC33 CTRP1 0.2890 37.0000
JZL-184 HCC4006 CTRP1 0.2891 37.0000
JZL-184 HCC44 CTRP1 0.2890 37.0000
JZL-184 HCC78 CTRP1 0.2890 37.0000
JZL-184 HCC827 CTRP1 0.2891 37.0000
JZL-184 KNS-62 CTRP1 0.2890 37.0000
JZL-184 LC-1-SQ-SF CTRP1 0.2890 37.0000
JZL-184 LCLC-103H CTRP1 0.2890 37.0000
JZL-184 LCLC-97TM1 CTRP1 0.2890 37.0000
JZL-184 LU-65 CTRP1 0.2890 37.0000
JZL-184 LU-99 CTRP1 0.2890 37.0000
JZL-184 LXF289 CTRP1 0.2890 37.0000
JZL-184 NCI-H1048 CTRP1 0.2890 37.0000
JZL-184 NCI-H1105 CTRP1 0.2891 37.0000
JZL-184 NCI-H1299 CTRP1 0.2890 37.0000
JZL-184 NCI-H1355 CTRP1 0.2890 37.0000
JZL-184 NCI-H1373 CTRP1 0.2890 37.0000
JZL-184 NCI-H1435 CTRP1 0.2890 37.0000
JZL-184 NCI-H1437 CTRP1 0.2890 37.0000
JZL-184 NCI-H1568 CTRP1 0.2890 37.0000
JZL-184 NCI-H1573 CTRP1 0.2890 37.0000
JZL-184 NCI-H1666 CTRP1 0.2890 37.0000
JZL-184 NCI-H1694 CTRP1 0.2891 37.0000
JZL-184 NCI-H1755 CTRP1 0.2891 37.0000
JZL-184 NCI-H1781 CTRP1 0.2891 37.0000
JZL-184 NCI-H1792 CTRP1 0.2890 37.0000
JZL-184 NCI-H1793 CTRP1 0.2890 37.0000
JZL-184 NCI-H1836 CTRP1 0.2891 37.0000
JZL-184 NCI-H1876 CTRP1 0.2891 37.0000
JZL-184 NCI-H1915 CTRP1 0.2890 37.0000
JZL-184 NCI-H1930 CTRP1 0.2890 37.0000
JZL-184 NCI-H1944 CTRP1 0.2890 37.0000
JZL-184 NCI-H1963 CTRP1 0.2891 37.0000
JZL-184 NCI-H1975 CTRP1 0.2890 37.0000
JZL-184 NCI-H2009 CTRP1 0.2890 37.0000
JZL-184 NCI-H2023 CTRP1 0.2891 37.0000
JZL-184 NCI-H2029 CTRP1 0.2890 37.0000
JZL-184 NCI-H2030 CTRP1 0.2891 37.0000
JZL-184 NCI-H2073 CTRP1 0.2891 37.0000
JZL-184 NCI-H2081 CTRP1 0.2891 37.0000
JZL-184 NCI-H2110 CTRP1 0.2891 37.0000
JZL-184 NCI-H2122 CTRP1 0.2891 37.0000
JZL-184 NCI-H2126 CTRP1 0.2890 37.0000
JZL-184 NCI-H2141 CTRP1 0.2891 37.0000
JZL-184 NCI-H2172 CTRP1 0.2891 37.0000
JZL-184 NCI-H2286 CTRP1 0.2890 37.0000
JZL-184 NCI-H23 CTRP1 0.2890 37.0000
JZL-184 NCI-H2342 CTRP1 0.2891 37.0000
JZL-184 NCI-H2405 CTRP1 0.2890 37.0000
JZL-184 NCI-H3255 CTRP1 0.2891 37.0000
JZL-184 NCI-H358 CTRP1 0.2890 37.0000
JZL-184 NCI-H441 CTRP1 0.2891 37.0000
JZL-184 NCI-H460 CTRP1 0.2891 37.0000
JZL-184 NCI-H522 CTRP1 0.2890 37.0000
JZL-184 NCI-H596 CTRP1 0.2891 37.0000
JZL-184 NCI-H650 CTRP1 0.2890 37.0000
JZL-184 NCI-H661 CTRP1 0.2890 37.0000
JZL-184 NCI-H727 CTRP1 0.2890 37.0000
JZL-184 NCI-H810 CTRP1 0.2890 37.0000
JZL-184 NCI-H82 CTRP1 0.2890 37.0000
JZL-184 NCI-H841 CTRP1 0.2891 37.0000
JZL-184 RERF-LC-KJ CTRP1 0.2890 37.0000
JZL-184 SCLC-21H CTRP1 0.2891 37.0000
JZL-184 SHP-77 CTRP1 0.2890 37.0000
JZL-184 SK-LU-1 CTRP1 0.2891 37.0000
JZL-184 SQ-1 CTRP1 0.2891 37.0000
JZL-184 T3M-10 CTRP1 0.2891 37.0000
JZL-184 VMRC-LCD CTRP1 0.2890 37.0000
JZL-184 KYSE-140 CTRP1 0.2890 37.0000
JZL-184 KYSE-410 CTRP1 0.2890 37.0000
JZL-184 KYSE-450 CTRP1 0.2890 37.0000
JZL-184 A2780 CTRP1 0.2891 37.0000
JZL-184 CAOV-3 CTRP1 0.2891 37.0000
JZL-184 COV318 CTRP1 0.2890 37.0000
JZL-184 COV362 CTRP1 0.2891 37.0000
JZL-184 COV434 CTRP1 0.2891 37.0000
JZL-184 COV644 CTRP1 0.2891 37.0000
JZL-184 EFO-21 CTRP1 0.2890 37.0000
JZL-184 EFO-27 CTRP1 0.2891 37.0000
JZL-184 HEYA8 CTRP1 0.2890 37.0000
JZL-184 IGROV-1 CTRP1 0.2891 37.0000
JZL-184 JHOC-5 CTRP1 0.2891 37.0000
JZL-184 JHOM-1 CTRP1 0.2891 37.0000
JZL-184 JHOS-4 CTRP1 0.2890 37.0000
JZL-184 OAW42 CTRP1 0.2891 37.0000
JZL-184 OV7 CTRP1 0.2891 37.0000
JZL-184 OV-90 CTRP1 0.2891 37.0000
JZL-184 OVCAR-4 CTRP1 0.2891 37.0000
JZL-184 OVCAR-8 CTRP1 0.2891 37.0000
JZL-184 OVK18 CTRP1 0.2891 37.0000
JZL-184 OVKATE CTRP1 0.2891 37.0000
JZL-184 OVMANA CTRP1 0.2890 37.0000
JZL-184 RKN CTRP1 0.2891 37.0000
JZL-184 RMG-I CTRP1 0.2891 37.0000
JZL-184 RMUG-S CTRP1 0.2891 37.0000
JZL-184 SK-OV-3 CTRP1 0.2890 37.0000
JZL-184 SNU-840 CTRP1 0.2891 37.0000
JZL-184 TYK-NU CTRP1 0.2891 37.0000
JZL-184 CAPAN-2 CTRP1 0.2890 37.0000
JZL-184 CFPAC-1 CTRP1 0.2890 37.0000
JZL-184 HPAC CTRP1 0.2890 37.0000
JZL-184 HUP-T4 CTRP1 0.2890 37.0000
JZL-184 KP-3 CTRP1 0.2890 37.0000
JZL-184 PANC03.27 CTRP1 0.2890 37.0000
JZL-184 PANC10.05 CTRP1 0.2890 37.0000
JZL-184 PATU8902 CTRP1 0.2890 37.0000
JZL-184 QGP-1 CTRP1 0.2890 37.0000
JZL-184 SUIT-2 CTRP1 0.2890 37.0000
JZL-184 MSTO-211H CTRP1 0.2890 37.0000
JZL-184 NCI-H2052 CTRP1 0.2890 37.0000
JZL-184 NCI-H28 CTRP1 0.2890 37.0000
JZL-184 MIAPACA-3 CTRP1 0.2890 37.0000
JZL-184 A-375 CTRP1 0.2891 37.0000
JZL-184 COLO741 CTRP1 0.2890 37.0000
JZL-184 G-361 CTRP1 0.2890 37.0000
JZL-184 HS852.T CTRP1 0.2890 37.0000
JZL-184 HS936.T CTRP1 0.2890 37.0000
JZL-184 HS944.T CTRP1 0.2890 37.0000
JZL-184 SK-MEL-1 CTRP1 0.2891 37.0000
JZL-184 SK-MEL-28 CTRP1 0.2891 37.0000
JZL-184 SK-MEL-5 CTRP1 0.2891 37.0000
JZL-184 G-401 CTRP1 0.2890 37.0000
JZL-184 HT-1080 CTRP1 0.2891 37.0000
JZL-184 AGS CTRP1 0.2891 37.0000
JZL-184 FU97 CTRP1 0.2890 37.0000
JZL-184 KE-97 CTRP1 0.2890 37.0000
JZL-184 MKN7 CTRP1 0.2890 37.0000
JZL-184 MKN74 CTRP1 0.2890 37.0000
JZL-184 NUGC-4 CTRP1 0.2890 37.0000
JZL-184 SH-10-TC CTRP1 0.2890 37.0000
JZL-184 HSC-2 CTRP1 0.2890 37.0000
JZL-184 SCC-9 CTRP1 0.2891 37.0000
JZL-184 5637 CTRP1 0.2890 37.0000
JZL-184 HT-1376 CTRP1 0.2890 37.0000
JZL-184 KMBC-2 CTRP1 0.2890 37.0000
JZL-184 RT-4 CTRP1 0.2890 37.0000
JZL-184 UM-UC-3 CTRP1 0.2890 37.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.