Drug : Idarubicin

CTRP1 Name : idarubicin

Dataset : All
Synonyms :
Targets : TOP2A;TOP2B
Pathways : inhibitor of topoisomerase II

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
idarubicin U2OS CTRP1 0.0020 0.2600
idarubicin MCF-7 CTRP1 0.0020 0.2600
idarubicin GAMG CTRP1 0.0027 33.3330
idarubicin LN-229 CTRP1 0.0020 0.2600
idarubicin SF295 CTRP1 0.2603 33.3330
idarubicin HEC-108 CTRP1 0.0027 33.3330
idarubicin HEC-151 CTRP1 0.0020 0.2600
idarubicin HEC-251 CTRP1 0.2603 33.3330
idarubicin HEC-265 CTRP1 0.2603 33.3330
idarubicin HEC-59 CTRP1 0.0027 33.3330
idarubicin HEC-6 CTRP1 0.2603 33.3330
idarubicin ISHIKAWA(HERAKLIO)02ER- CTRP1 0.0027 33.3330
idarubicin JHUEM-2 CTRP1 0.0020 0.2600
idarubicin KLE CTRP1 0.0027 33.3330
idarubicin MFE-319 CTRP1 0.2603 33.3330
idarubicin SNG-M CTRP1 0.0027 33.3330
idarubicin AMO1 CTRP1 0.0020 0.2600
idarubicin BL-70 CTRP1 0.0027 33.3330
idarubicin EJM CTRP1 0.0020 0.2600
idarubicin GDM-1 CTRP1 0.0020 0.2600
idarubicin HT CTRP1 0.2603 33.3330
idarubicin KMS-11 CTRP1 0.0020 0.2600
idarubicin KU812 CTRP1 0.2603 33.3330
idarubicin LP-1 CTRP1 0.0020 0.2600
idarubicin MC116 CTRP1 0.2603 33.3330
idarubicin MOLM-16 CTRP1 0.0020 0.2600
idarubicin NOMO-1 CTRP1 0.0020 0.2600
idarubicin NU-DUL-1 CTRP1 0.0020 0.2600
idarubicin OCI-AML-3 CTRP1 0.0020 0.2600
idarubicin OCI-LY10 CTRP1 0.0020 0.2600
idarubicin P3HR-1 CTRP1 0.2603 33.3330
idarubicin PL21 CTRP1 0.0020 0.2600
idarubicin RPMI-8226 CTRP1 0.0020 0.2600
idarubicin SKM-1 CTRP1 0.0020 0.2600
idarubicin SU-DHL-4 CTRP1 0.0020 0.2600
idarubicin SU-DHL-5 CTRP1 0.0020 0.2600
idarubicin THP-1 CTRP1 0.0020 0.2600
idarubicin U-937 CTRP1 0.0020 0.2600
idarubicin WSU-DLCL2 CTRP1 0.0020 0.2600
idarubicin RCC10RGB CTRP1 0.0020 0.2600
idarubicin VMRC-RCW CTRP1 0.2603 33.3330
idarubicin C2BBE1 CTRP1 0.2603 33.3330
idarubicin CL-34 CTRP1 0.0020 0.2600
idarubicin CL-40 CTRP1 0.0020 0.2600
idarubicin COLO205 CTRP1 0.2603 33.3330
idarubicin COLO320 CTRP1 0.0020 0.1300
idarubicin COLO678 CTRP1 0.0020 0.2600
idarubicin CW-2 CTRP1 0.0020 0.2600
idarubicin DLD-1 CTRP1 0.2603 33.3330
idarubicin GP2D CTRP1 0.2603 33.3330
idarubicin HCT116 CTRP1 0.0020 0.2600
idarubicin HCT8 CTRP1 0.0020 0.2600
idarubicin HT115 CTRP1 0.0020 0.2600
idarubicin HT-29 CTRP1 0.0020 0.2600
idarubicin HT-55 CTRP1 0.0020 0.2600
idarubicin KM12 CTRP1 0.0020 0.2600
idarubicin LOVO CTRP1 0.0020 0.2600
idarubicin LS123 CTRP1 0.0020 0.2600
idarubicin LS180 CTRP1 0.0020 0.2600
idarubicin LS411N CTRP1 0.2603 33.3330
idarubicin LS513 CTRP1 0.2603 33.3330
idarubicin MDST8 CTRP1 0.0020 0.2600
idarubicin NCI-H508 CTRP1 0.0020 0.2600
idarubicin RCM-1[HUMANESC] CTRP1 0.0020 0.2600
idarubicin RKO CTRP1 0.0020 0.2600
idarubicin SK-CO-1 CTRP1 0.2603 33.3330
idarubicin SNU-1040 CTRP1 0.0020 0.2600
idarubicin SNU-175 CTRP1 0.0020 0.2600
idarubicin SNU-61 CTRP1 0.0020 0.2600
idarubicin SNU-81 CTRP1 0.0020 0.2600
idarubicin SNU-C2A CTRP1 0.2603 33.3330
idarubicin SNU-C4 CTRP1 0.0020 0.2600
idarubicin SNU-C5 CTRP1 0.0020 0.2600
idarubicin SW403 CTRP1 0.2603 33.3330
idarubicin SW48 CTRP1 0.2603 33.3330
idarubicin SW480 CTRP1 0.0020 0.2600
idarubicin SW620 CTRP1 0.0020 0.2600
idarubicin SW948 CTRP1 0.0020 0.2600
idarubicin HEP-G2 CTRP1 0.0020 0.2600
idarubicin JHH-6 CTRP1 0.0027 33.3330
idarubicin SNU-398 CTRP1 0.0020 0.2600
idarubicin SNU-449 CTRP1 0.0027 33.3330
idarubicin A-549 CTRP1 0.2603 33.3330
idarubicin BEN CTRP1 0.2603 33.3330
idarubicin CAL-12T CTRP1 0.0020 0.2600
idarubicin CALU-3 CTRP1 0.2603 33.3330
idarubicin CALU-6 CTRP1 0.2603 33.3330
idarubicin CHAGO-K-1 CTRP1 0.2603 33.3330
idarubicin COLO668 CTRP1 0.0027 33.3330
idarubicin COLO699 CTRP1 0.0020 0.2600
idarubicin COR-L23 CTRP1 0.0020 0.2600
idarubicin COR-L279 CTRP1 0.2603 33.3330
idarubicin COR-L51 CTRP1 0.0020 0.2600
idarubicin COR-L88 CTRP1 0.2603 33.3330
idarubicin DMS273 CTRP1 0.2603 33.3330
idarubicin DV-90 CTRP1 0.2603 33.3330
idarubicin EBC-1 CTRP1 0.2603 33.3330
idarubicin EPLC-272H CTRP1 0.2603 33.3330
idarubicin HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
idarubicin HCC1195 CTRP1 0.0020 0.2600
idarubicin HCC1359 CTRP1 0.0020 0.2600
idarubicin HCC15 CTRP1 0.0020 0.2600
idarubicin HCC1833 CTRP1 0.0020 0.2600
idarubicin HCC2108 CTRP1 0.0020 0.2600
idarubicin HCC2935 CTRP1 0.0020 0.2600
idarubicin HCC33 CTRP1 0.2603 33.3330
idarubicin HCC4006 CTRP1 0.0020 0.2600
idarubicin HCC44 CTRP1 0.2603 33.3330
idarubicin HCC78 CTRP1 0.2603 33.3330
idarubicin HCC827 CTRP1 0.0020 0.2600
idarubicin KNS-62 CTRP1 0.2603 33.3330
idarubicin LC-1-SQ-SF CTRP1 0.2603 33.3330
idarubicin LCLC-103H CTRP1 0.2603 33.3330
idarubicin LCLC-97TM1 CTRP1 0.2603 33.3330
idarubicin LU-65 CTRP1 0.2603 33.3330
idarubicin LU-99 CTRP1 0.2603 33.3330
idarubicin LXF289 CTRP1 0.0027 33.3330
idarubicin NCI-H1048 CTRP1 0.2603 33.3330
idarubicin NCI-H1105 CTRP1 0.0020 0.2600
idarubicin NCI-H1299 CTRP1 0.2603 33.3330
idarubicin NCI-H1355 CTRP1 0.2603 33.3330
idarubicin NCI-H1373 CTRP1 0.2603 33.3330
idarubicin NCI-H1435 CTRP1 0.0027 33.3330
idarubicin NCI-H1437 CTRP1 0.2603 33.3330
idarubicin NCI-H1568 CTRP1 0.2603 33.3330
idarubicin NCI-H1573 CTRP1 0.2603 33.3330
idarubicin NCI-H1666 CTRP1 0.2603 33.3330
idarubicin NCI-H1694 CTRP1 0.0020 0.2600
idarubicin NCI-H1755 CTRP1 0.0020 0.2600
idarubicin NCI-H1781 CTRP1 0.0020 0.2600
idarubicin NCI-H1792 CTRP1 0.2603 33.3330
idarubicin NCI-H1793 CTRP1 0.2603 33.3330
idarubicin NCI-H1836 CTRP1 0.0020 0.2600
idarubicin NCI-H1876 CTRP1 0.0020 0.2600
idarubicin NCI-H1915 CTRP1 0.0027 33.3330
idarubicin NCI-H1930 CTRP1 0.0027 33.3330
idarubicin NCI-H1944 CTRP1 0.2603 33.3330
idarubicin NCI-H1963 CTRP1 0.0020 0.2600
idarubicin NCI-H1975 CTRP1 0.2603 33.3330
idarubicin NCI-H2009 CTRP1 0.0020 33.3330
idarubicin NCI-H2023 CTRP1 0.0020 0.2600
idarubicin NCI-H2029 CTRP1 0.2603 33.3330
idarubicin NCI-H2030 CTRP1 0.0020 0.2600
idarubicin NCI-H2073 CTRP1 0.0020 0.2600
idarubicin NCI-H2081 CTRP1 0.0020 0.2600
idarubicin NCI-H2110 CTRP1 0.0020 0.2600
idarubicin NCI-H2122 CTRP1 0.0020 0.2600
idarubicin NCI-H2126 CTRP1 0.2603 33.3330
idarubicin NCI-H2141 CTRP1 0.0020 0.2600
idarubicin NCI-H2172 CTRP1 0.0020 0.2600
idarubicin NCI-H2286 CTRP1 0.0027 33.3330
idarubicin NCI-H23 CTRP1 0.2603 33.3330
idarubicin NCI-H2342 CTRP1 0.0020 0.2600
idarubicin NCI-H2405 CTRP1 0.2603 33.3330
idarubicin NCI-H3255 CTRP1 0.0020 0.2600
idarubicin NCI-H358 CTRP1 0.2603 33.3330
idarubicin NCI-H441 CTRP1 0.0020 0.2600
idarubicin NCI-H460 CTRP1 0.0020 0.2600
idarubicin NCI-H522 CTRP1 0.2603 33.3330
idarubicin NCI-H596 CTRP1 0.0020 0.2600
idarubicin NCI-H650 CTRP1 0.2603 33.3330
idarubicin NCI-H661 CTRP1 0.2603 33.3330
idarubicin NCI-H727 CTRP1 0.2603 33.3330
idarubicin NCI-H810 CTRP1 0.2603 33.3330
idarubicin NCI-H82 CTRP1 0.2603 33.3330
idarubicin NCI-H841 CTRP1 0.0020 0.2600
idarubicin RERF-LC-KJ CTRP1 0.0027 33.3330
idarubicin SCLC-21H CTRP1 0.0020 0.2600
idarubicin SHP-77 CTRP1 0.2603 33.3330
idarubicin SK-LU-1 CTRP1 0.0020 0.2600
idarubicin SQ-1 CTRP1 0.0020 0.2600
idarubicin T3M-10 CTRP1 0.0020 0.2600
idarubicin VMRC-LCD CTRP1 0.2603 33.3330
idarubicin KYSE-140 CTRP1 0.2603 33.3330
idarubicin KYSE-410 CTRP1 0.2603 33.3330
idarubicin KYSE-450 CTRP1 0.2603 33.3330
idarubicin A2780 CTRP1 0.0020 0.2600
idarubicin CAOV-3 CTRP1 0.0020 0.2600
idarubicin COV318 CTRP1 0.0027 33.3330
idarubicin COV362 CTRP1 0.0020 0.2600
idarubicin COV434 CTRP1 0.0020 0.2600
idarubicin COV644 CTRP1 0.0020 0.2600
idarubicin EFO-21 CTRP1 0.2603 33.3330
idarubicin EFO-27 CTRP1 0.0020 0.2600
idarubicin HEYA8 CTRP1 0.2603 33.3330
idarubicin IGROV-1 CTRP1 0.0020 0.2600
idarubicin JHOC-5 CTRP1 0.0020 0.2600
idarubicin JHOM-1 CTRP1 0.0020 0.2600
idarubicin JHOS-4 CTRP1 0.0027 33.3330
idarubicin OAW42 CTRP1 0.0020 0.2600
idarubicin OV7 CTRP1 0.0020 0.2600
idarubicin OV-90 CTRP1 0.0020 0.2600
idarubicin OVCAR-4 CTRP1 0.0020 0.2600
idarubicin OVCAR-8 CTRP1 0.0020 0.2600
idarubicin OVK18 CTRP1 0.0020 0.2600
idarubicin OVKATE CTRP1 0.0020 0.2600
idarubicin OVMANA CTRP1 0.0027 33.3330
idarubicin RKN CTRP1 0.0020 0.2600
idarubicin RMG-I CTRP1 0.0020 0.2600
idarubicin RMUG-S CTRP1 0.0020 0.2600
idarubicin SK-OV-3 CTRP1 0.2603 33.3330
idarubicin SNU-840 CTRP1 0.0020 0.2600
idarubicin TYK-NU CTRP1 0.0020 0.2600
idarubicin CAPAN-2 CTRP1 0.2603 33.3330
idarubicin CFPAC-1 CTRP1 0.2603 33.3330
idarubicin HPAC CTRP1 0.2603 33.3330
idarubicin HUP-T4 CTRP1 0.2603 33.3330
idarubicin KP-3 CTRP1 0.2603 33.3330
idarubicin PANC03.27 CTRP1 0.2603 33.3330
idarubicin PANC10.05 CTRP1 0.2603 33.3330
idarubicin PATU8902 CTRP1 0.0027 33.3330
idarubicin QGP-1 CTRP1 0.2603 33.3330
idarubicin SUIT-2 CTRP1 0.2603 33.3330
idarubicin MSTO-211H CTRP1 0.2603 33.3330
idarubicin NCI-H2052 CTRP1 0.2603 33.3330
idarubicin NCI-H28 CTRP1 0.2603 33.3330
idarubicin MIAPACA-3 CTRP1 0.0027 33.3330
idarubicin A-375 CTRP1 0.0020 0.2600
idarubicin COLO741 CTRP1 0.2603 33.3330
idarubicin G-361 CTRP1 0.2603 33.3330
idarubicin HS852.T CTRP1 0.0027 33.3330
idarubicin HS936.T CTRP1 0.2603 33.3330
idarubicin HS944.T CTRP1 0.2603 33.3330
idarubicin SK-MEL-1 CTRP1 0.0020 0.2600
idarubicin SK-MEL-28 CTRP1 0.0020 0.2600
idarubicin SK-MEL-5 CTRP1 0.0020 0.2600
idarubicin G-401 CTRP1 0.2603 33.3330
idarubicin HT-1080 CTRP1 0.0020 0.2600
idarubicin AGS CTRP1 0.0020 0.2600
idarubicin FU97 CTRP1 0.2603 33.3330
idarubicin KE-97 CTRP1 0.2603 33.3330
idarubicin MKN7 CTRP1 0.2603 33.3330
idarubicin MKN74 CTRP1 0.0027 33.3330
idarubicin NUGC-4 CTRP1 0.2603 33.3330
idarubicin SH-10-TC CTRP1 0.2603 33.3330
idarubicin HSC-2 CTRP1 0.2603 33.3330
idarubicin SCC-9 CTRP1 0.0020 0.2600
idarubicin 5637 CTRP1 0.2603 33.3330
idarubicin HT-1376 CTRP1 0.2603 33.3330
idarubicin KMBC-2 CTRP1 0.2603 33.3330
idarubicin RT-4 CTRP1 0.2603 33.3330
idarubicin UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.