Drug : Batimastat

CTRP1 Name : batimastat

Dataset : All
Synonyms :
Targets : MMP1;MMP2;MMP3;MMP7;MMP9
Pathways : inhibitor of matrix metallopeptidase 1, 2, 3, 7 and 9

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
batimastat U2OS CTRP1 1.1562 148.0000
batimastat MCF-7 CTRP1 1.1562 148.0000
batimastat GAMG CTRP1 0.2890 37.0000
batimastat LN-229 CTRP1 1.1562 148.0000
batimastat SF295 CTRP1 0.2890 37.0000
batimastat HEC-108 CTRP1 0.2890 37.0000
batimastat HEC-151 CTRP1 1.1562 148.0000
batimastat HEC-251 CTRP1 0.2890 37.0000
batimastat HEC-265 CTRP1 0.2890 37.0000
batimastat HEC-59 CTRP1 0.2890 37.0000
batimastat HEC-6 CTRP1 0.2890 37.0000
batimastat ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2890 37.0000
batimastat JHUEM-2 CTRP1 1.1562 148.0000
batimastat KLE CTRP1 0.2890 37.0000
batimastat MFE-319 CTRP1 0.2890 37.0000
batimastat SNG-M CTRP1 0.2890 37.0000
batimastat AMO1 CTRP1 1.1562 148.0000
batimastat BL-70 CTRP1 0.2890 37.0000
batimastat EJM CTRP1 1.1562 148.0000
batimastat GDM-1 CTRP1 1.1562 148.0000
batimastat HT CTRP1 0.2890 37.0000
batimastat KMS-11 CTRP1 1.1562 148.0000
batimastat KU812 CTRP1 0.2890 37.0000
batimastat LP-1 CTRP1 1.1562 148.0000
batimastat MC116 CTRP1 0.2890 37.0000
batimastat MOLM-16 CTRP1 1.1562 148.0000
batimastat NOMO-1 CTRP1 1.1562 148.0000
batimastat NU-DUL-1 CTRP1 1.1562 148.0000
batimastat OCI-AML-3 CTRP1 1.1562 148.0000
batimastat OCI-LY10 CTRP1 1.1562 148.0000
batimastat P3HR-1 CTRP1 0.2890 37.0000
batimastat PL21 CTRP1 1.1562 148.0000
batimastat RPMI-8226 CTRP1 1.1562 148.0000
batimastat SKM-1 CTRP1 1.1562 148.0000
batimastat SU-DHL-4 CTRP1 1.1562 148.0000
batimastat SU-DHL-5 CTRP1 1.1562 148.0000
batimastat THP-1 CTRP1 1.1562 148.0000
batimastat U-937 CTRP1 1.1562 148.0000
batimastat WSU-DLCL2 CTRP1 1.1562 148.0000
batimastat RCC10RGB CTRP1 1.1562 148.0000
batimastat VMRC-RCW CTRP1 0.2890 37.0000
batimastat C2BBE1 CTRP1 0.2890 37.0000
batimastat CL-34 CTRP1 1.1562 148.0000
batimastat CL-40 CTRP1 1.1562 148.0000
batimastat COLO205 CTRP1 0.2890 37.0000
batimastat COLO320 CTRP1 1.1562 148.0000
batimastat COLO678 CTRP1 1.1562 148.0000
batimastat CW-2 CTRP1 1.1562 148.0000
batimastat DLD-1 CTRP1 0.2890 37.0000
batimastat GP2D CTRP1 0.2890 37.0000
batimastat HCT116 CTRP1 1.1562 148.0000
batimastat HCT8 CTRP1 1.1562 148.0000
batimastat HT115 CTRP1 1.1562 148.0000
batimastat HT-29 CTRP1 1.1562 148.0000
batimastat HT-55 CTRP1 1.1562 148.0000
batimastat KM12 CTRP1 1.1562 148.0000
batimastat LOVO CTRP1 1.1562 148.0000
batimastat LS123 CTRP1 1.1562 148.0000
batimastat LS180 CTRP1 1.1562 148.0000
batimastat LS411N CTRP1 0.2890 37.0000
batimastat LS513 CTRP1 0.2890 37.0000
batimastat MDST8 CTRP1 1.1562 148.0000
batimastat NCI-H508 CTRP1 1.1562 148.0000
batimastat RCM-1[HUMANESC] CTRP1 1.1562 148.0000
batimastat RKO CTRP1 1.1562 148.0000
batimastat SK-CO-1 CTRP1 0.2890 37.0000
batimastat SNU-1040 CTRP1 1.1562 148.0000
batimastat SNU-175 CTRP1 1.1562 148.0000
batimastat SNU-61 CTRP1 1.1562 148.0000
batimastat SNU-81 CTRP1 1.1562 148.0000
batimastat SNU-C2A CTRP1 0.2890 37.0000
batimastat SNU-C4 CTRP1 1.1562 148.0000
batimastat SNU-C5 CTRP1 1.1562 148.0000
batimastat SW403 CTRP1 0.2890 37.0000
batimastat SW48 CTRP1 0.2890 37.0000
batimastat SW480 CTRP1 1.1562 148.0000
batimastat SW620 CTRP1 1.1562 148.0000
batimastat SW948 CTRP1 1.1562 148.0000
batimastat HEP-G2 CTRP1 1.1562 148.0000
batimastat JHH-6 CTRP1 0.2890 37.0000
batimastat SNU-398 CTRP1 1.1562 148.0000
batimastat SNU-449 CTRP1 0.2890 37.0000
batimastat A-549 CTRP1 0.2890 37.0000
batimastat BEN CTRP1 0.2890 37.0000
batimastat CAL-12T CTRP1 1.1562 148.0000
batimastat CALU-3 CTRP1 0.2890 37.0000
batimastat CALU-6 CTRP1 0.2890 37.0000
batimastat CHAGO-K-1 CTRP1 0.2890 37.0000
batimastat COLO668 CTRP1 0.2890 37.0000
batimastat COLO699 CTRP1 1.1562 148.0000
batimastat COR-L23 CTRP1 1.1562 148.0000
batimastat COR-L279 CTRP1 0.2890 37.0000
batimastat COR-L51 CTRP1 1.1562 148.0000
batimastat COR-L88 CTRP1 0.2890 37.0000
batimastat DMS273 CTRP1 0.2890 37.0000
batimastat DV-90 CTRP1 0.2890 37.0000
batimastat EBC-1 CTRP1 0.2890 37.0000
batimastat EPLC-272H CTRP1 0.2890 37.0000
batimastat HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2890 37.0000
batimastat HCC1195 CTRP1 1.1562 148.0000
batimastat HCC1359 CTRP1 1.1562 148.0000
batimastat HCC15 CTRP1 1.1562 148.0000
batimastat HCC1833 CTRP1 1.1562 148.0000
batimastat HCC2108 CTRP1 1.1562 148.0000
batimastat HCC2935 CTRP1 1.1562 148.0000
batimastat HCC33 CTRP1 0.2890 37.0000
batimastat HCC4006 CTRP1 1.1562 148.0000
batimastat HCC44 CTRP1 0.2890 37.0000
batimastat HCC78 CTRP1 0.2890 37.0000
batimastat HCC827 CTRP1 1.1562 148.0000
batimastat KNS-62 CTRP1 0.2890 37.0000
batimastat LC-1-SQ-SF CTRP1 0.2890 37.0000
batimastat LCLC-103H CTRP1 0.2890 37.0000
batimastat LCLC-97TM1 CTRP1 0.2890 37.0000
batimastat LU-65 CTRP1 0.2890 37.0000
batimastat LU-99 CTRP1 0.2890 37.0000
batimastat LXF289 CTRP1 0.2890 37.0000
batimastat NCI-H1048 CTRP1 0.2890 37.0000
batimastat NCI-H1105 CTRP1 1.1562 148.0000
batimastat NCI-H1299 CTRP1 0.2890 37.0000
batimastat NCI-H1355 CTRP1 0.2890 37.0000
batimastat NCI-H1373 CTRP1 0.2890 37.0000
batimastat NCI-H1435 CTRP1 0.2890 37.0000
batimastat NCI-H1437 CTRP1 0.2890 37.0000
batimastat NCI-H1568 CTRP1 0.2890 37.0000
batimastat NCI-H1573 CTRP1 0.2890 37.0000
batimastat NCI-H1666 CTRP1 0.2890 37.0000
batimastat NCI-H1694 CTRP1 1.1562 148.0000
batimastat NCI-H1755 CTRP1 1.1562 148.0000
batimastat NCI-H1781 CTRP1 1.1562 148.0000
batimastat NCI-H1792 CTRP1 0.2890 37.0000
batimastat NCI-H1793 CTRP1 0.2890 37.0000
batimastat NCI-H1836 CTRP1 1.1562 148.0000
batimastat NCI-H1876 CTRP1 1.1562 148.0000
batimastat NCI-H1915 CTRP1 0.2890 37.0000
batimastat NCI-H1930 CTRP1 0.2890 37.0000
batimastat NCI-H1944 CTRP1 0.2890 37.0000
batimastat NCI-H1963 CTRP1 1.1562 148.0000
batimastat NCI-H1975 CTRP1 0.2890 37.0000
batimastat NCI-H2009 CTRP1 0.2890 37.0000
batimastat NCI-H2023 CTRP1 1.1562 148.0000
batimastat NCI-H2029 CTRP1 0.2890 37.0000
batimastat NCI-H2030 CTRP1 1.1562 148.0000
batimastat NCI-H2073 CTRP1 1.1562 148.0000
batimastat NCI-H2081 CTRP1 1.1562 148.0000
batimastat NCI-H2110 CTRP1 1.1562 148.0000
batimastat NCI-H2122 CTRP1 1.1562 148.0000
batimastat NCI-H2126 CTRP1 0.2890 37.0000
batimastat NCI-H2141 CTRP1 1.1562 148.0000
batimastat NCI-H2172 CTRP1 1.1562 148.0000
batimastat NCI-H2286 CTRP1 0.2890 37.0000
batimastat NCI-H23 CTRP1 0.2890 37.0000
batimastat NCI-H2342 CTRP1 1.1562 148.0000
batimastat NCI-H2405 CTRP1 0.2890 37.0000
batimastat NCI-H3255 CTRP1 1.1562 148.0000
batimastat NCI-H358 CTRP1 0.2890 37.0000
batimastat NCI-H441 CTRP1 1.1562 148.0000
batimastat NCI-H460 CTRP1 1.1562 148.0000
batimastat NCI-H522 CTRP1 0.2890 37.0000
batimastat NCI-H596 CTRP1 1.1562 148.0000
batimastat NCI-H650 CTRP1 0.2890 37.0000
batimastat NCI-H661 CTRP1 0.2890 37.0000
batimastat NCI-H727 CTRP1 0.2890 37.0000
batimastat NCI-H810 CTRP1 0.2890 37.0000
batimastat NCI-H82 CTRP1 0.2890 37.0000
batimastat NCI-H841 CTRP1 1.1562 148.0000
batimastat RERF-LC-KJ CTRP1 0.2890 37.0000
batimastat SCLC-21H CTRP1 1.1562 148.0000
batimastat SHP-77 CTRP1 0.2890 37.0000
batimastat SK-LU-1 CTRP1 1.1562 148.0000
batimastat SQ-1 CTRP1 1.1562 148.0000
batimastat T3M-10 CTRP1 1.1562 148.0000
batimastat VMRC-LCD CTRP1 0.2890 37.0000
batimastat KYSE-140 CTRP1 0.2890 37.0000
batimastat KYSE-410 CTRP1 0.2890 37.0000
batimastat KYSE-450 CTRP1 0.2890 37.0000
batimastat A2780 CTRP1 1.1562 148.0000
batimastat CAOV-3 CTRP1 1.1562 148.0000
batimastat COV318 CTRP1 0.2890 37.0000
batimastat COV362 CTRP1 1.1562 148.0000
batimastat COV434 CTRP1 1.1562 148.0000
batimastat COV644 CTRP1 1.1562 148.0000
batimastat EFO-21 CTRP1 0.2890 37.0000
batimastat EFO-27 CTRP1 1.1562 148.0000
batimastat HEYA8 CTRP1 0.2890 37.0000
batimastat IGROV-1 CTRP1 1.1562 148.0000
batimastat JHOC-5 CTRP1 1.1562 148.0000
batimastat JHOM-1 CTRP1 1.1562 148.0000
batimastat JHOS-4 CTRP1 0.2890 37.0000
batimastat OAW42 CTRP1 1.1562 148.0000
batimastat OV7 CTRP1 1.1562 148.0000
batimastat OV-90 CTRP1 1.1562 148.0000
batimastat OVCAR-4 CTRP1 1.1562 148.0000
batimastat OVCAR-8 CTRP1 1.1562 148.0000
batimastat OVK18 CTRP1 1.1562 148.0000
batimastat OVKATE CTRP1 1.1562 148.0000
batimastat OVMANA CTRP1 0.2890 37.0000
batimastat RKN CTRP1 1.1562 148.0000
batimastat RMG-I CTRP1 1.1562 148.0000
batimastat RMUG-S CTRP1 1.1562 148.0000
batimastat SK-OV-3 CTRP1 0.2890 37.0000
batimastat SNU-840 CTRP1 1.1562 148.0000
batimastat TYK-NU CTRP1 1.1562 148.0000
batimastat CAPAN-2 CTRP1 0.2890 37.0000
batimastat CFPAC-1 CTRP1 0.2890 37.0000
batimastat HPAC CTRP1 0.2890 37.0000
batimastat HUP-T4 CTRP1 0.2890 37.0000
batimastat KP-3 CTRP1 0.2890 37.0000
batimastat PANC03.27 CTRP1 0.2890 37.0000
batimastat PANC10.05 CTRP1 0.2890 37.0000
batimastat PATU8902 CTRP1 0.2890 37.0000
batimastat QGP-1 CTRP1 0.2890 37.0000
batimastat SUIT-2 CTRP1 0.2890 37.0000
batimastat MSTO-211H CTRP1 0.2890 37.0000
batimastat NCI-H2052 CTRP1 0.2890 37.0000
batimastat NCI-H28 CTRP1 0.2890 37.0000
batimastat MIAPACA-3 CTRP1 0.2890 37.0000
batimastat A-375 CTRP1 1.1562 148.0000
batimastat COLO741 CTRP1 0.2890 37.0000
batimastat G-361 CTRP1 0.2890 37.0000
batimastat HS852.T CTRP1 0.2890 37.0000
batimastat HS936.T CTRP1 0.2890 37.0000
batimastat HS944.T CTRP1 0.2890 37.0000
batimastat SK-MEL-1 CTRP1 1.1562 148.0000
batimastat SK-MEL-28 CTRP1 1.1562 148.0000
batimastat SK-MEL-5 CTRP1 1.1562 148.0000
batimastat G-401 CTRP1 0.2890 37.0000
batimastat HT-1080 CTRP1 1.1562 148.0000
batimastat AGS CTRP1 1.1562 148.0000
batimastat FU97 CTRP1 0.2890 37.0000
batimastat KE-97 CTRP1 0.2890 37.0000
batimastat MKN7 CTRP1 0.2890 37.0000
batimastat MKN74 CTRP1 0.2890 37.0000
batimastat NUGC-4 CTRP1 0.2890 37.0000
batimastat SH-10-TC CTRP1 0.2890 37.0000
batimastat HSC-2 CTRP1 0.2890 37.0000
batimastat SCC-9 CTRP1 1.1562 148.0000
batimastat 5637 CTRP1 0.2890 37.0000
batimastat HT-1376 CTRP1 0.2890 37.0000
batimastat KMBC-2 CTRP1 0.2890 37.0000
batimastat RT-4 CTRP1 0.2890 37.0000
batimastat UM-UC-3 CTRP1 0.2890 37.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.