Drug : Nvp-Auy922

CTRP1 Name : NVP-AUY922

Dataset : All
Synonyms :
Targets : HSP90AA1;HSP90B1
Pathways : inhibitor of HSP90? and HSP90?

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
NVP-AUY922 U2OS CTRP1 0.0001 33.3330
NVP-AUY922 MCF-7 CTRP1 0.0001 33.3330
NVP-AUY922 GAMG CTRP1 0.2603 33.3330
NVP-AUY922 LN-229 CTRP1 0.0001 33.3330
NVP-AUY922 SF295 CTRP1 0.2603 33.3330
NVP-AUY922 HEC-108 CTRP1 0.2603 33.3330
NVP-AUY922 HEC-151 CTRP1 0.0001 33.3330
NVP-AUY922 HEC-251 CTRP1 0.2603 33.3330
NVP-AUY922 HEC-265 CTRP1 0.2603 33.3330
NVP-AUY922 HEC-59 CTRP1 0.2603 33.3330
NVP-AUY922 HEC-6 CTRP1 0.2603 33.3330
NVP-AUY922 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
NVP-AUY922 JHUEM-2 CTRP1 0.0001 33.3330
NVP-AUY922 KLE CTRP1 0.2603 33.3330
NVP-AUY922 MFE-319 CTRP1 0.2603 33.3330
NVP-AUY922 SNG-M CTRP1 0.2603 33.3330
NVP-AUY922 AMO1 CTRP1 0.0001 33.3330
NVP-AUY922 BL-70 CTRP1 0.2603 33.3330
NVP-AUY922 EJM CTRP1 0.0001 33.3330
NVP-AUY922 GDM-1 CTRP1 0.0001 33.3330
NVP-AUY922 HT CTRP1 0.2603 33.3330
NVP-AUY922 KMS-11 CTRP1 0.0001 33.3330
NVP-AUY922 KU812 CTRP1 0.2603 33.3330
NVP-AUY922 LP-1 CTRP1 0.0001 33.3330
NVP-AUY922 MC116 CTRP1 0.2603 33.3330
NVP-AUY922 MOLM-16 CTRP1 0.0001 33.3330
NVP-AUY922 NOMO-1 CTRP1 0.0001 33.3330
NVP-AUY922 NU-DUL-1 CTRP1 0.0001 33.3330
NVP-AUY922 OCI-AML-3 CTRP1 0.0001 33.3330
NVP-AUY922 OCI-LY10 CTRP1 0.0001 33.3330
NVP-AUY922 P3HR-1 CTRP1 0.2603 33.3330
NVP-AUY922 PL21 CTRP1 0.0001 33.3330
NVP-AUY922 RPMI-8226 CTRP1 0.0001 33.3330
NVP-AUY922 SKM-1 CTRP1 0.0001 33.3330
NVP-AUY922 SU-DHL-4 CTRP1 0.0001 33.3330
NVP-AUY922 SU-DHL-5 CTRP1 0.0001 33.3330
NVP-AUY922 THP-1 CTRP1 0.0001 33.3330
NVP-AUY922 U-937 CTRP1 0.0001 33.3330
NVP-AUY922 WSU-DLCL2 CTRP1 0.0001 33.3330
NVP-AUY922 RCC10RGB CTRP1 0.0001 33.3330
NVP-AUY922 VMRC-RCW CTRP1 0.2603 33.3330
NVP-AUY922 CL-34 CTRP1 0.0001 33.3330
NVP-AUY922 CL-40 CTRP1 0.0001 33.3330
NVP-AUY922 COLO320 CTRP1 0.0001 33.3330
NVP-AUY922 COLO678 CTRP1 0.0001 33.3330
NVP-AUY922 CW-2 CTRP1 0.0001 33.3330
NVP-AUY922 HCT116 CTRP1 0.0001 33.3330
NVP-AUY922 HCT8 CTRP1 0.0001 33.3330
NVP-AUY922 HT115 CTRP1 0.0001 33.3330
NVP-AUY922 HT-29 CTRP1 0.0001 33.3330
NVP-AUY922 HT-55 CTRP1 0.0001 33.3330
NVP-AUY922 KM12 CTRP1 0.0001 33.3330
NVP-AUY922 LOVO CTRP1 0.0001 33.3330
NVP-AUY922 LS123 CTRP1 0.0001 33.3330
NVP-AUY922 LS180 CTRP1 0.0001 33.3330
NVP-AUY922 MDST8 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H508 CTRP1 0.0001 33.3330
NVP-AUY922 RCM-1[HUMANESC] CTRP1 0.0001 33.3330
NVP-AUY922 RKO CTRP1 0.0001 33.3330
NVP-AUY922 SNU-1040 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-175 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-61 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-81 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-C2A CTRP1 0.2603 33.3330
NVP-AUY922 SNU-C4 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-C5 CTRP1 0.0001 33.3330
NVP-AUY922 SW403 CTRP1 0.2603 33.3330
NVP-AUY922 SW480 CTRP1 0.0001 33.3330
NVP-AUY922 SW620 CTRP1 0.0001 33.3330
NVP-AUY922 SW948 CTRP1 0.0001 33.3330
NVP-AUY922 HEP-G2 CTRP1 0.0001 33.3330
NVP-AUY922 JHH-6 CTRP1 0.2603 33.3330
NVP-AUY922 SNU-398 CTRP1 0.0001 33.3330
NVP-AUY922 SNU-449 CTRP1 0.2603 33.3330
NVP-AUY922 A-549 CTRP1 0.2603 33.3330
NVP-AUY922 CAL-12T CTRP1 0.0001 33.3330
NVP-AUY922 CALU-3 CTRP1 0.2603 33.3330
NVP-AUY922 CALU-6 CTRP1 0.2603 33.3330
NVP-AUY922 CHAGO-K-1 CTRP1 0.2603 33.3330
NVP-AUY922 COLO668 CTRP1 0.2603 33.3330
NVP-AUY922 COLO699 CTRP1 0.0001 33.3330
NVP-AUY922 COR-L23 CTRP1 0.0001 33.3330
NVP-AUY922 COR-L279 CTRP1 0.2603 33.3330
NVP-AUY922 COR-L51 CTRP1 0.0001 33.3330
NVP-AUY922 COR-L88 CTRP1 0.2603 33.3330
NVP-AUY922 DMS273 CTRP1 0.2603 33.3330
NVP-AUY922 EPLC-272H CTRP1 0.2603 33.3330
NVP-AUY922 HCC1195 CTRP1 0.0001 33.3330
NVP-AUY922 HCC1359 CTRP1 0.0001 33.3330
NVP-AUY922 HCC15 CTRP1 0.0001 33.3330
NVP-AUY922 HCC1833 CTRP1 0.0001 33.3330
NVP-AUY922 HCC2108 CTRP1 0.0001 33.3330
NVP-AUY922 HCC2935 CTRP1 0.0001 33.3330
NVP-AUY922 HCC4006 CTRP1 0.0001 33.3330
NVP-AUY922 HCC827 CTRP1 0.0001 33.3330
NVP-AUY922 KNS-62 CTRP1 0.2603 33.3330
NVP-AUY922 LCLC-97TM1 CTRP1 0.2603 33.3330
NVP-AUY922 LXF289 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1048 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1105 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1299 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1355 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1435 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1437 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1568 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1573 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1666 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1694 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1755 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1781 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1792 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1836 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1876 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1915 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1930 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1944 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H1963 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H1975 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H2009 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2023 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2029 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H2030 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2073 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2081 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2110 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2122 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2141 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2172 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2286 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H23 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H2342 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H2405 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H3255 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H441 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H460 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H596 CTRP1 0.0001 33.3330
NVP-AUY922 NCI-H650 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H810 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H82 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H841 CTRP1 0.0001 33.3330
NVP-AUY922 RERF-LC-KJ CTRP1 0.2603 33.3330
NVP-AUY922 SCLC-21H CTRP1 0.0001 33.3330
NVP-AUY922 SK-LU-1 CTRP1 0.0001 33.3330
NVP-AUY922 SQ-1 CTRP1 0.0001 33.3330
NVP-AUY922 T3M-10 CTRP1 0.0001 33.3330
NVP-AUY922 VMRC-LCD CTRP1 0.2603 33.3330
NVP-AUY922 KYSE-140 CTRP1 0.2603 33.3330
NVP-AUY922 KYSE-410 CTRP1 0.2603 33.3330
NVP-AUY922 KYSE-450 CTRP1 0.2603 33.3330
NVP-AUY922 A2780 CTRP1 0.0001 33.3330
NVP-AUY922 CAOV-3 CTRP1 0.0001 33.3330
NVP-AUY922 COV318 CTRP1 0.2603 33.3330
NVP-AUY922 COV362 CTRP1 0.0001 33.3330
NVP-AUY922 COV434 CTRP1 0.0001 33.3330
NVP-AUY922 COV644 CTRP1 0.0001 33.3330
NVP-AUY922 EFO-21 CTRP1 0.2603 33.3330
NVP-AUY922 EFO-27 CTRP1 0.0001 33.3330
NVP-AUY922 HEYA8 CTRP1 0.2603 33.3330
NVP-AUY922 IGROV-1 CTRP1 0.0001 33.3330
NVP-AUY922 JHOC-5 CTRP1 0.0001 33.3330
NVP-AUY922 JHOM-1 CTRP1 0.0001 33.3330
NVP-AUY922 JHOS-4 CTRP1 0.2603 33.3330
NVP-AUY922 OAW42 CTRP1 0.0001 33.3330
NVP-AUY922 OV7 CTRP1 0.0001 33.3330
NVP-AUY922 OV-90 CTRP1 0.0001 33.3330
NVP-AUY922 OVCAR-4 CTRP1 0.0001 33.3330
NVP-AUY922 OVCAR-8 CTRP1 0.0001 33.3330
NVP-AUY922 OVK18 CTRP1 0.0001 33.3330
NVP-AUY922 OVKATE CTRP1 0.0001 33.3330
NVP-AUY922 OVMANA CTRP1 0.2603 33.3330
NVP-AUY922 RKN CTRP1 0.0001 33.3330
NVP-AUY922 RMG-I CTRP1 0.0001 33.3330
NVP-AUY922 RMUG-S CTRP1 0.0001 33.3330
NVP-AUY922 SK-OV-3 CTRP1 0.2603 33.3330
NVP-AUY922 SNU-840 CTRP1 0.0001 33.3330
NVP-AUY922 TYK-NU CTRP1 0.0001 33.3330
NVP-AUY922 CAPAN-2 CTRP1 0.2603 33.3330
NVP-AUY922 HUP-T4 CTRP1 0.2603 33.3330
NVP-AUY922 KP-3 CTRP1 0.2603 33.3330
NVP-AUY922 PANC03.27 CTRP1 0.2603 33.3330
NVP-AUY922 PATU8902 CTRP1 0.2603 33.3330
NVP-AUY922 QGP-1 CTRP1 0.2603 33.3330
NVP-AUY922 SUIT-2 CTRP1 0.2603 33.3330
NVP-AUY922 MSTO-211H CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H2052 CTRP1 0.2603 33.3330
NVP-AUY922 NCI-H28 CTRP1 0.2603 33.3330
NVP-AUY922 MIAPACA-3 CTRP1 0.2603 33.3330
NVP-AUY922 A-375 CTRP1 0.0001 33.3330
NVP-AUY922 G-361 CTRP1 0.2603 33.3330
NVP-AUY922 HS852.T CTRP1 0.2603 33.3330
NVP-AUY922 HS936.T CTRP1 0.2603 33.3330
NVP-AUY922 HS944.T CTRP1 0.2603 33.3330
NVP-AUY922 SK-MEL-1 CTRP1 0.0001 33.3330
NVP-AUY922 SK-MEL-28 CTRP1 0.0001 33.3330
NVP-AUY922 SK-MEL-5 CTRP1 0.0001 33.3330
NVP-AUY922 G-401 CTRP1 0.2603 33.3330
NVP-AUY922 HT-1080 CTRP1 0.0001 33.3330
NVP-AUY922 AGS CTRP1 0.0001 33.3330
NVP-AUY922 FU97 CTRP1 0.2603 33.3330
NVP-AUY922 KE-97 CTRP1 0.2603 33.3330
NVP-AUY922 MKN7 CTRP1 0.2603 33.3330
NVP-AUY922 MKN74 CTRP1 0.2603 33.3330
NVP-AUY922 NUGC-4 CTRP1 0.2603 33.3330
NVP-AUY922 SH-10-TC CTRP1 0.2603 33.3330
NVP-AUY922 HSC-2 CTRP1 0.2603 33.3330
NVP-AUY922 SCC-9 CTRP1 0.0001 33.3330
NVP-AUY922 5637 CTRP1 0.2603 33.3330
NVP-AUY922 HT-1376 CTRP1 0.2603 33.3330
NVP-AUY922 KMBC-2 CTRP1 0.2603 33.3330
NVP-AUY922 RT-4 CTRP1 0.2603 33.3330
NVP-AUY922 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.