Drug : Chaetocin

CTRP1 Name : chaetocin

Dataset : All
Synonyms :
Targets : SUV39H1
Pathways : natural product;modulator of histone methyl-transferase SUV39H1;modulator of ROS levels

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
chaetocin U2OS CTRP1 0.0020 0.2600
chaetocin MCF-7 CTRP1 0.0020 0.2600
chaetocin GAMG CTRP1 0.2603 33.3330
chaetocin LN-229 CTRP1 0.0020 0.2600
chaetocin HEC-108 CTRP1 0.2603 33.3330
chaetocin HEC-151 CTRP1 0.0020 0.2600
chaetocin HEC-59 CTRP1 0.2603 33.3330
chaetocin ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
chaetocin JHUEM-2 CTRP1 0.0020 0.2600
chaetocin KLE CTRP1 0.2603 33.3330
chaetocin SNG-M CTRP1 0.2603 33.3330
chaetocin AMO1 CTRP1 0.0020 0.2600
chaetocin BL-70 CTRP1 0.2603 33.3330
chaetocin EJM CTRP1 0.0020 0.2600
chaetocin GDM-1 CTRP1 0.0020 0.2600
chaetocin KMS-11 CTRP1 0.0020 0.2600
chaetocin LP-1 CTRP1 0.0020 0.2600
chaetocin MOLM-16 CTRP1 0.0020 0.2600
chaetocin NOMO-1 CTRP1 0.0020 0.2600
chaetocin NU-DUL-1 CTRP1 0.0020 0.2600
chaetocin OCI-AML-3 CTRP1 0.0020 0.2600
chaetocin OCI-LY10 CTRP1 0.0020 0.2600
chaetocin PL21 CTRP1 0.0020 0.2600
chaetocin RPMI-8226 CTRP1 0.0020 0.2600
chaetocin SKM-1 CTRP1 0.0020 0.2600
chaetocin SU-DHL-4 CTRP1 0.0020 0.2600
chaetocin SU-DHL-5 CTRP1 0.0020 0.2600
chaetocin THP-1 CTRP1 0.0020 0.2600
chaetocin U-937 CTRP1 0.0020 0.2600
chaetocin WSU-DLCL2 CTRP1 0.0020 0.2600
chaetocin RCC10RGB CTRP1 0.0020 0.2600
chaetocin CL-34 CTRP1 0.0020 0.2600
chaetocin CL-40 CTRP1 0.0020 0.2600
chaetocin COLO320 CTRP1 0.0020 0.2600
chaetocin COLO678 CTRP1 0.0020 0.2600
chaetocin CW-2 CTRP1 0.0020 0.2600
chaetocin HCT116 CTRP1 0.0020 0.2600
chaetocin HCT8 CTRP1 0.0020 0.2600
chaetocin HT115 CTRP1 0.0020 0.2600
chaetocin HT-29 CTRP1 0.0020 0.2600
chaetocin HT-55 CTRP1 0.0020 0.2600
chaetocin KM12 CTRP1 0.0020 0.2600
chaetocin LOVO CTRP1 0.0020 0.2600
chaetocin LS123 CTRP1 0.0020 0.2600
chaetocin LS180 CTRP1 0.0020 0.2600
chaetocin MDST8 CTRP1 0.0020 0.2600
chaetocin NCI-H508 CTRP1 0.0020 0.2600
chaetocin RCM-1[HUMANESC] CTRP1 0.0020 0.2600
chaetocin RKO CTRP1 0.0020 0.2600
chaetocin SNU-1040 CTRP1 0.0020 0.2600
chaetocin SNU-175 CTRP1 0.0020 0.2600
chaetocin SNU-61 CTRP1 0.0020 0.2600
chaetocin SNU-81 CTRP1 0.0020 0.2600
chaetocin SNU-C4 CTRP1 0.0020 0.2600
chaetocin SNU-C5 CTRP1 0.0020 0.2600
chaetocin SW480 CTRP1 0.0020 0.2600
chaetocin SW620 CTRP1 0.0020 0.2600
chaetocin SW948 CTRP1 0.0020 0.2600
chaetocin HEP-G2 CTRP1 0.0020 0.2600
chaetocin JHH-6 CTRP1 0.2603 33.3330
chaetocin SNU-398 CTRP1 0.0020 0.2600
chaetocin SNU-449 CTRP1 0.2603 33.3330
chaetocin CAL-12T CTRP1 0.0020 0.2600
chaetocin COLO668 CTRP1 0.2603 33.3330
chaetocin COLO699 CTRP1 0.0020 0.2600
chaetocin COR-L23 CTRP1 0.0020 0.2600
chaetocin COR-L51 CTRP1 0.0020 0.2600
chaetocin HCC1195 CTRP1 0.0020 0.2600
chaetocin HCC1359 CTRP1 0.0020 0.2600
chaetocin HCC15 CTRP1 0.0020 0.2600
chaetocin HCC1833 CTRP1 0.0020 0.2600
chaetocin HCC2108 CTRP1 0.0020 0.2600
chaetocin HCC2935 CTRP1 0.0020 0.2600
chaetocin HCC4006 CTRP1 0.0020 0.2600
chaetocin HCC827 CTRP1 0.0020 0.2600
chaetocin LXF289 CTRP1 0.2603 33.3330
chaetocin NCI-H1105 CTRP1 0.0020 0.2600
chaetocin NCI-H1435 CTRP1 0.2603 33.3330
chaetocin NCI-H1694 CTRP1 0.0020 0.2600
chaetocin NCI-H1755 CTRP1 0.0020 0.2600
chaetocin NCI-H1781 CTRP1 0.0020 0.2600
chaetocin NCI-H1836 CTRP1 0.0020 0.2600
chaetocin NCI-H1876 CTRP1 0.0020 0.2600
chaetocin NCI-H1915 CTRP1 0.2603 33.3330
chaetocin NCI-H1930 CTRP1 0.2603 33.3330
chaetocin NCI-H1963 CTRP1 0.0020 0.2600
chaetocin NCI-H2009 CTRP1 0.0020 0.2600
chaetocin NCI-H2023 CTRP1 0.0020 0.2600
chaetocin NCI-H2030 CTRP1 0.0020 0.2600
chaetocin NCI-H2073 CTRP1 0.0020 0.2600
chaetocin NCI-H2081 CTRP1 0.0020 0.2600
chaetocin NCI-H2110 CTRP1 0.0020 0.2600
chaetocin NCI-H2122 CTRP1 0.0020 0.2600
chaetocin NCI-H2141 CTRP1 0.0020 0.2600
chaetocin NCI-H2172 CTRP1 0.0020 0.2600
chaetocin NCI-H2286 CTRP1 0.2603 33.3330
chaetocin NCI-H2342 CTRP1 0.0020 0.2600
chaetocin NCI-H3255 CTRP1 0.0020 0.2600
chaetocin NCI-H441 CTRP1 0.0020 0.2600
chaetocin NCI-H460 CTRP1 0.0020 0.2600
chaetocin NCI-H596 CTRP1 0.0020 0.2600
chaetocin NCI-H841 CTRP1 0.0020 0.2600
chaetocin RERF-LC-KJ CTRP1 0.2603 33.3330
chaetocin SCLC-21H CTRP1 0.0020 0.2600
chaetocin SK-LU-1 CTRP1 0.0020 0.2600
chaetocin SQ-1 CTRP1 0.0020 0.2600
chaetocin T3M-10 CTRP1 0.0020 0.2600
chaetocin A2780 CTRP1 0.0020 0.2600
chaetocin CAOV-3 CTRP1 0.0020 0.2600
chaetocin COV318 CTRP1 0.2603 33.3330
chaetocin COV362 CTRP1 0.0020 0.2600
chaetocin COV434 CTRP1 0.0020 0.2600
chaetocin COV644 CTRP1 0.0020 0.2600
chaetocin EFO-27 CTRP1 0.0020 0.2600
chaetocin IGROV-1 CTRP1 0.0020 0.2600
chaetocin JHOC-5 CTRP1 0.0020 0.2600
chaetocin JHOM-1 CTRP1 0.0020 0.2600
chaetocin JHOS-4 CTRP1 0.2603 33.3330
chaetocin OAW42 CTRP1 0.0020 0.2600
chaetocin OV7 CTRP1 0.0020 0.2600
chaetocin OV-90 CTRP1 0.0020 0.2600
chaetocin OVCAR-4 CTRP1 0.0020 0.2600
chaetocin OVCAR-8 CTRP1 0.0020 0.2600
chaetocin OVK18 CTRP1 0.0020 0.2600
chaetocin OVKATE CTRP1 0.0020 0.2600
chaetocin OVMANA CTRP1 0.2603 33.3330
chaetocin RKN CTRP1 0.0020 0.2600
chaetocin RMG-I CTRP1 0.0020 0.2600
chaetocin RMUG-S CTRP1 0.0020 0.2600
chaetocin SNU-840 CTRP1 0.0020 0.2600
chaetocin TYK-NU CTRP1 0.0020 0.2600
chaetocin PATU8902 CTRP1 0.2603 33.3330
chaetocin MIAPACA-3 CTRP1 0.2603 33.3330
chaetocin A-375 CTRP1 0.0020 0.2600
chaetocin HS852.T CTRP1 0.2603 33.3330
chaetocin SK-MEL-1 CTRP1 0.0020 0.2600
chaetocin SK-MEL-28 CTRP1 0.0020 0.2600
chaetocin SK-MEL-5 CTRP1 0.0020 0.2600
chaetocin HT-1080 CTRP1 0.0020 0.2600
chaetocin AGS CTRP1 0.0020 0.2600
chaetocin MKN74 CTRP1 0.2603 33.3330
chaetocin SCC-9 CTRP1 0.0020 0.2600

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.