Drug : Brd1429

CTRP1 Name : BRD1429

Dataset : All
Synonyms :
Targets :
Pathways : screening hit

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD1429 LN-229 CTRP1 0.2604 33.3330
BRD1429 JHUEM-2 CTRP1 0.2604 33.3330
BRD1429 GDM-1 CTRP1 0.2604 33.3330
BRD1429 MOLM-16 CTRP1 0.2604 33.3330
BRD1429 NOMO-1 CTRP1 0.2604 33.3330
BRD1429 NU-DUL-1 CTRP1 0.2604 33.3330
BRD1429 OCI-AML-3 CTRP1 0.2604 33.3330
BRD1429 PL21 CTRP1 0.2604 33.3330
BRD1429 RPMI-8226 CTRP1 0.2604 33.3330
BRD1429 SKM-1 CTRP1 0.2604 33.3330
BRD1429 SU-DHL-4 CTRP1 0.2604 33.3330
BRD1429 SU-DHL-5 CTRP1 0.2604 33.3330
BRD1429 THP-1 CTRP1 0.2604 33.3330
BRD1429 U-937 CTRP1 0.2604 33.3330
BRD1429 WSU-DLCL2 CTRP1 0.2604 33.3330
BRD1429 CL-34 CTRP1 0.2604 33.3330
BRD1429 CL-40 CTRP1 0.2604 33.3330
BRD1429 COLO320 CTRP1 0.2604 33.3330
BRD1429 COLO678 CTRP1 0.2604 33.3330
BRD1429 CW-2 CTRP1 0.2604 33.3330
BRD1429 HCT116 CTRP1 0.2604 33.3330
BRD1429 HCT8 CTRP1 0.2604 33.3330
BRD1429 HT115 CTRP1 0.2604 33.3330
BRD1429 HT-29 CTRP1 0.2604 33.3330
BRD1429 HT-55 CTRP1 0.2604 33.3330
BRD1429 KM12 CTRP1 0.2604 33.3330
BRD1429 LOVO CTRP1 0.2604 33.3330
BRD1429 LS123 CTRP1 0.2604 33.3330
BRD1429 MDST8 CTRP1 0.2604 33.3330
BRD1429 NCI-H508 CTRP1 0.2604 33.3330
BRD1429 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
BRD1429 RKO CTRP1 0.2604 33.3330
BRD1429 SNU-1040 CTRP1 0.2604 33.3330
BRD1429 SNU-175 CTRP1 0.2604 33.3330
BRD1429 SNU-61 CTRP1 0.2604 33.3330
BRD1429 SNU-81 CTRP1 0.2604 33.3330
BRD1429 SNU-C4 CTRP1 0.2604 33.3330
BRD1429 SNU-C5 CTRP1 0.2604 33.3330
BRD1429 SW480 CTRP1 0.2604 33.3330
BRD1429 SW620 CTRP1 0.2604 33.3330
BRD1429 SW948 CTRP1 0.2604 33.3330
BRD1429 COR-L23 CTRP1 0.2604 33.3330
BRD1429 HCC15 CTRP1 0.2604 33.3330
BRD1429 NCI-H1755 CTRP1 0.2604 33.3330
BRD1429 NCI-H1781 CTRP1 0.2604 33.3330
BRD1429 NCI-H1836 CTRP1 0.2604 33.3330
BRD1429 NCI-H2073 CTRP1 0.2604 33.3330
BRD1429 NCI-H2110 CTRP1 0.2604 33.3330
BRD1429 NCI-H2122 CTRP1 0.2604 33.3330
BRD1429 NCI-H3255 CTRP1 0.2604 33.3330
BRD1429 NCI-H441 CTRP1 0.2604 33.3330
BRD1429 NCI-H460 CTRP1 0.2604 33.3330
BRD1429 NCI-H596 CTRP1 0.2604 33.3330
BRD1429 SK-LU-1 CTRP1 0.2604 33.3330
BRD1429 T3M-10 CTRP1 0.2604 33.3330
BRD1429 CAOV-3 CTRP1 0.2604 33.3330
BRD1429 COV362 CTRP1 0.2604 33.3330
BRD1429 COV644 CTRP1 0.2604 33.3330
BRD1429 OV7 CTRP1 0.2604 33.3330
BRD1429 OV-90 CTRP1 0.2604 33.3330
BRD1429 RMG-I CTRP1 0.2604 33.3330
BRD1429 RMUG-S CTRP1 0.2604 33.3330
BRD1429 SNU-840 CTRP1 0.2604 33.3330
BRD1429 TYK-NU CTRP1 0.2604 33.3330
BRD1429 A-375 CTRP1 0.2604 33.3330
BRD1429 SK-MEL-1 CTRP1 0.2604 33.3330
BRD1429 SK-MEL-28 CTRP1 0.2604 33.3330
BRD1429 SK-MEL-5 CTRP1 0.2604 33.3330
BRD1429 HT-1080 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.