Drug : Ro-28-1675
CTRP1 Name
: Ro-28-1675
Dataset : All
Synonyms :
Targets : GCK
Pathways : activator of glucokinase
Information Cards
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Drug name | Cellosaurus ID | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| Ro-28-1675 | MCF-7 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | GAMG | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | LN-229 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | SF295 | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | HEC-108 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HEC-151 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HEC-251 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HEC-265 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HEC-59 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HEC-6 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | ISHIKAWA(HERAKLIO)02ER- | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | JHUEM-2 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | KLE | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MFE-319 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SNG-M | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | AMO1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | BL-70 | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | EJM | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | GDM-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HT | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KMS-11 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | KU812 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LP-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | MC116 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MOLM-16 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NOMO-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NU-DUL-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OCI-AML-3 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | OCI-LY10 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | P3HR-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | PL21 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RPMI-8226 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SKM-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SU-DHL-4 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SU-DHL-5 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | THP-1 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | U-937 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | WSU-DLCL2 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RCC10RGB | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | VMRC-RCW | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | C2BBE1 | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | CL-34 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | CL-40 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COLO205 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | COLO320 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COLO678 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | CW-2 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | DLD-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | GP2D | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HCT116 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCT8 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HT115 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HT-29 | CTRP1 | 4.1667 | 533.3300 |
|
| Ro-28-1675 | HT-55 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | KM12 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | LOVO | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | LS123 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | LS180 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | LS411N | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LS513 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MDST8 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H508 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RCM-1[HUMANESC] | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RKO | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SK-CO-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SNU-1040 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-175 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-61 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-81 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-C2A | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SNU-C4 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-C5 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SW403 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SW48 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SW480 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SW620 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SW948 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HEP-G2 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | JHH-6 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SNU-398 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SNU-449 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | A-549 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | BEN | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | CAL-12T | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | CALU-3 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | CALU-6 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | CHAGO-K-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | COLO668 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | COLO699 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COR-L23 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COR-L279 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | COR-L51 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COR-L88 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | DMS273 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | DV-90 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | EBC-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | EPLC-272H | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HCC1195 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC1359 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC15 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC1833 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC2108 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC2935 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC33 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HCC4006 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HCC44 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HCC78 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HCC827 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | KNS-62 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LC-1-SQ-SF | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LCLC-103H | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LCLC-97TM1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LU-65 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LU-99 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | LXF289 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1048 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1105 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1299 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1355 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1373 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1435 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1437 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1568 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1573 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1666 | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | NCI-H1694 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1755 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1781 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1792 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1793 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1836 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1876 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1915 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1930 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1944 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H1963 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H1975 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2009 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2023 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2029 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2030 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2073 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2081 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2110 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2122 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2126 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2141 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2172 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2286 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H23 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2342 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H2405 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H3255 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H358 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H441 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H460 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H522 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H596 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | NCI-H650 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H661 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H727 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H810 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H82 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H841 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RERF-LC-KJ | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SCLC-21H | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SHP-77 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SK-LU-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SQ-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | T3M-10 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | VMRC-LCD | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KYSE-140 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KYSE-410 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KYSE-450 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | A2780 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | CAOV-3 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COV318 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | COV362 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COV434 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COV644 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | EFO-21 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | EFO-27 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | HEYA8 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | IGROV-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | JHOC-5 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | JHOM-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | JHOS-4 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | OAW42 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OV7 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OV-90 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OVCAR-4 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OVCAR-8 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OVK18 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OVKATE | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | OVMANA | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | RKN | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RMG-I | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | RMUG-S | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SK-OV-3 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SNU-840 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | TYK-NU | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | CAPAN-2 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | CFPAC-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HPAC | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HUP-T4 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KP-3 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | PANC03.27 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | PANC10.05 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | PATU8902 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | QGP-1 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SUIT-2 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MSTO-211H | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H2052 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NCI-H28 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MIAPACA-3 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | A-375 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | COLO741 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | G-361 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HS852.T | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HS936.T | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HS944.T | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SK-MEL-1 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SK-MEL-28 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | SK-MEL-5 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | G-401 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HT-1080 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | AGS | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | FU97 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KE-97 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MKN7 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | MKN74 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | NUGC-4 | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | SH-10-TC | CTRP1 | 0.2603 | 33.3330 |
|
| Ro-28-1675 | HSC-2 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | SCC-9 | CTRP1 | 4.1667 | 533.3300 |
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| Ro-28-1675 | 5637 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | HT-1376 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | KMBC-2 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | RT-4 | CTRP1 | 0.2603 | 33.3330 |
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| Ro-28-1675 | UM-UC-3 | CTRP1 | 0.2603 | 33.3330 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Cell lines with highest and lowest IC50
Cell lines with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Cell lines with highest and lowest IC90
Cell lines with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Cell lines with highest and lowest AUC
Cell lines with highest and lowest AUC
Associated Genes (Mutation)
Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from
pancan data.
Associated Genes (Gene Expression)
Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from
pancan data.