CREAMMIST

Drug : Brd4354

CTRP1 Name : BRD4354

Dataset : All
Synonyms :
Targets :
Pathways : screening hit

Information Cards

Click to show/hide information cards below or download all drug response information.

Experiment Information IC50 IC90 AUC
Associated Genes (Mutation) Associated Genes (Gene Expression)

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name	Cellosaurus ID	Original Dataset(s)	Min Dose	Max Dose
BRD4354	LN-229	CTRP1	0.2604	33.3330
BRD4354	JHUEM-2	CTRP1	0.2604	33.3330
BRD4354	GDM-1	CTRP1	0.2604	33.3330
BRD4354	MOLM-16	CTRP1	0.2604	33.3330
BRD4354	NOMO-1	CTRP1	0.2604	33.3330
BRD4354	NU-DUL-1	CTRP1	0.2604	33.3330
BRD4354	OCI-AML-3	CTRP1	0.2604	33.3330
BRD4354	PL21	CTRP1	0.2604	33.3330
BRD4354	RPMI-8226	CTRP1	0.2604	33.3330
BRD4354	SKM-1	CTRP1	0.2604	33.3330
BRD4354	SU-DHL-4	CTRP1	0.2604	33.3330
BRD4354	SU-DHL-5	CTRP1	0.2604	33.3330
BRD4354	THP-1	CTRP1	0.2604	33.3330
BRD4354	U-937	CTRP1	0.2604	33.3330
BRD4354	WSU-DLCL2	CTRP1	0.2604	33.3330
BRD4354	CL-34	CTRP1	0.2604	33.3330
BRD4354	CL-40	CTRP1	0.2604	33.3330
BRD4354	COLO320	CTRP1	0.2604	33.3330
BRD4354	COLO678	CTRP1	0.2604	33.3330
BRD4354	CW-2	CTRP1	0.2604	33.3330
BRD4354	HCT116	CTRP1	0.2604	33.3330
BRD4354	HCT8	CTRP1	0.2604	33.3330
BRD4354	HT115	CTRP1	0.2604	33.3330
BRD4354	HT-29	CTRP1	0.2604	33.3330
BRD4354	HT-55	CTRP1	0.2604	33.3330
BRD4354	KM12	CTRP1	0.2604	33.3330
BRD4354	LOVO	CTRP1	0.2604	33.3330
BRD4354	LS123	CTRP1	0.2604	33.3330
BRD4354	MDST8	CTRP1	0.2604	33.3330
BRD4354	NCI-H508	CTRP1	0.2604	33.3330
BRD4354	RCM-1[HUMANESC]	CTRP1	0.2604	33.3330
BRD4354	RKO	CTRP1	0.2604	33.3330
BRD4354	SNU-1040	CTRP1	0.2604	33.3330
BRD4354	SNU-175	CTRP1	0.2604	33.3330
BRD4354	SNU-61	CTRP1	0.2604	33.3330
BRD4354	SNU-81	CTRP1	0.2604	33.3330
BRD4354	SNU-C4	CTRP1	0.2604	33.3330
BRD4354	SNU-C5	CTRP1	0.2604	33.3330
BRD4354	SW480	CTRP1	0.2604	33.3330
BRD4354	SW620	CTRP1	0.2604	33.3330
BRD4354	SW948	CTRP1	0.2604	33.3330
BRD4354	COR-L23	CTRP1	0.2604	33.3330
BRD4354	HCC15	CTRP1	0.2604	33.3330
BRD4354	NCI-H1755	CTRP1	0.2604	33.3330
BRD4354	NCI-H1781	CTRP1	0.2604	33.3330
BRD4354	NCI-H1836	CTRP1	0.2604	33.3330
BRD4354	NCI-H2073	CTRP1	0.2604	33.3330
BRD4354	NCI-H2110	CTRP1	0.2604	33.3330
BRD4354	NCI-H2122	CTRP1	0.2604	33.3330
BRD4354	NCI-H3255	CTRP1	0.2604	33.3330
BRD4354	NCI-H441	CTRP1	0.2604	33.3330
BRD4354	NCI-H460	CTRP1	0.2604	33.3330
BRD4354	NCI-H596	CTRP1	0.2604	33.3330
BRD4354	SK-LU-1	CTRP1	0.2604	33.3330
BRD4354	T3M-10	CTRP1	0.2604	33.3330
BRD4354	CAOV-3	CTRP1	0.2604	33.3330
BRD4354	COV362	CTRP1	0.2604	33.3330
BRD4354	COV644	CTRP1	0.2604	33.3330
BRD4354	OV7	CTRP1	0.2604	33.3330
BRD4354	OV-90	CTRP1	0.2604	33.3330
BRD4354	RMG-I	CTRP1	0.2604	33.3330
BRD4354	RMUG-S	CTRP1	0.2604	33.3330
BRD4354	SNU-840	CTRP1	0.2604	33.3330
BRD4354	TYK-NU	CTRP1	0.2604	33.3330
BRD4354	A-375	CTRP1	0.2604	33.3330
BRD4354	SK-MEL-1	CTRP1	0.2604	33.3330
BRD4354	SK-MEL-28	CTRP1	0.2604	33.3330
BRD4354	SK-MEL-5	CTRP1	0.2604	33.3330
BRD4354	HT-1080	CTRP1	0.2604	33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.