Drug : Gant-58

CTRP1 Name : GANT-58

Dataset : All
Synonyms :
Targets : GLI1
Pathways : inhibitor of GLI1-induced transcription

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
GANT-58 MCF-7 CTRP1 0.2604 33.3330
GANT-58 LN-229 CTRP1 0.2604 33.3330
GANT-58 JHUEM-2 CTRP1 0.2604 33.3330
GANT-58 EJM CTRP1 0.2604 33.3330
GANT-58 GDM-1 CTRP1 0.2604 33.3330
GANT-58 MOLM-16 CTRP1 0.2604 33.3330
GANT-58 NOMO-1 CTRP1 0.2604 33.3330
GANT-58 NU-DUL-1 CTRP1 0.2604 33.3330
GANT-58 OCI-AML-3 CTRP1 0.2604 33.3330
GANT-58 PL21 CTRP1 0.2604 33.3330
GANT-58 RPMI-8226 CTRP1 0.2604 33.3330
GANT-58 SKM-1 CTRP1 0.2604 33.3330
GANT-58 SU-DHL-4 CTRP1 0.2604 33.3330
GANT-58 SU-DHL-5 CTRP1 0.2604 33.3330
GANT-58 THP-1 CTRP1 0.2604 33.3330
GANT-58 U-937 CTRP1 0.2604 33.3330
GANT-58 WSU-DLCL2 CTRP1 0.2604 33.3330
GANT-58 CL-34 CTRP1 0.2604 33.3330
GANT-58 CL-40 CTRP1 0.2604 33.3330
GANT-58 COLO320 CTRP1 0.2604 33.3330
GANT-58 COLO678 CTRP1 0.2604 33.3330
GANT-58 CW-2 CTRP1 0.2604 33.3330
GANT-58 HCT116 CTRP1 0.2604 33.3330
GANT-58 HCT8 CTRP1 0.2604 33.3330
GANT-58 HT115 CTRP1 0.2604 33.3330
GANT-58 HT-29 CTRP1 0.2604 33.3330
GANT-58 HT-55 CTRP1 0.2604 33.3330
GANT-58 KM12 CTRP1 0.2604 33.3330
GANT-58 LOVO CTRP1 0.2604 33.3330
GANT-58 LS123 CTRP1 0.2604 33.3330
GANT-58 MDST8 CTRP1 0.2604 33.3330
GANT-58 NCI-H508 CTRP1 0.2604 33.3330
GANT-58 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
GANT-58 RKO CTRP1 0.2604 33.3330
GANT-58 SNU-1040 CTRP1 0.2604 33.3330
GANT-58 SNU-175 CTRP1 0.2604 33.3330
GANT-58 SNU-61 CTRP1 0.2604 33.3330
GANT-58 SNU-81 CTRP1 0.2604 33.3330
GANT-58 SNU-C4 CTRP1 0.2604 33.3330
GANT-58 SNU-C5 CTRP1 0.2604 33.3330
GANT-58 SW480 CTRP1 0.2604 33.3330
GANT-58 SW620 CTRP1 0.2604 33.3330
GANT-58 SW948 CTRP1 0.2604 33.3330
GANT-58 HEP-G2 CTRP1 0.2604 33.3330
GANT-58 CAL-12T CTRP1 0.2604 33.3330
GANT-58 COLO699 CTRP1 0.2604 33.3330
GANT-58 COR-L23 CTRP1 0.2604 33.3330
GANT-58 HCC1195 CTRP1 0.2604 33.3330
GANT-58 HCC1359 CTRP1 0.2604 33.3330
GANT-58 HCC15 CTRP1 0.2604 33.3330
GANT-58 HCC1833 CTRP1 0.2604 33.3330
GANT-58 HCC2108 CTRP1 0.2604 33.3330
GANT-58 HCC2935 CTRP1 0.2604 33.3330
GANT-58 HCC4006 CTRP1 0.2604 33.3330
GANT-58 HCC827 CTRP1 0.2604 33.3330
GANT-58 NCI-H1105 CTRP1 0.2604 33.3330
GANT-58 NCI-H1694 CTRP1 0.2604 33.3330
GANT-58 NCI-H1755 CTRP1 0.2604 33.3330
GANT-58 NCI-H1781 CTRP1 0.2604 33.3330
GANT-58 NCI-H1836 CTRP1 0.2604 33.3330
GANT-58 NCI-H1876 CTRP1 0.2604 33.3330
GANT-58 NCI-H2023 CTRP1 0.2604 33.3330
GANT-58 NCI-H2030 CTRP1 0.2604 33.3330
GANT-58 NCI-H2073 CTRP1 0.2604 33.3330
GANT-58 NCI-H2081 CTRP1 0.2604 33.3330
GANT-58 NCI-H2110 CTRP1 0.2604 33.3330
GANT-58 NCI-H2122 CTRP1 0.2604 33.3330
GANT-58 NCI-H2172 CTRP1 0.2604 33.3330
GANT-58 NCI-H2342 CTRP1 0.2604 33.3330
GANT-58 NCI-H3255 CTRP1 0.2604 33.3330
GANT-58 NCI-H441 CTRP1 0.2604 33.3330
GANT-58 NCI-H460 CTRP1 0.2604 33.3330
GANT-58 NCI-H596 CTRP1 0.2604 33.3330
GANT-58 NCI-H841 CTRP1 0.2604 33.3330
GANT-58 SK-LU-1 CTRP1 0.2604 33.3330
GANT-58 SQ-1 CTRP1 0.2604 33.3330
GANT-58 T3M-10 CTRP1 0.2604 33.3330
GANT-58 CAOV-3 CTRP1 0.2604 33.3330
GANT-58 COV362 CTRP1 0.2604 33.3330
GANT-58 COV434 CTRP1 0.2604 33.3330
GANT-58 COV644 CTRP1 0.2604 33.3330
GANT-58 EFO-27 CTRP1 0.2604 33.3330
GANT-58 JHOC-5 CTRP1 0.2604 33.3330
GANT-58 JHOM-1 CTRP1 0.2604 33.3330
GANT-58 OAW42 CTRP1 0.2604 33.3330
GANT-58 OV7 CTRP1 0.2604 33.3330
GANT-58 OV-90 CTRP1 0.2604 33.3330
GANT-58 OVK18 CTRP1 0.2604 33.3330
GANT-58 RMG-I CTRP1 0.2604 33.3330
GANT-58 RMUG-S CTRP1 0.2604 33.3330
GANT-58 SNU-840 CTRP1 0.2604 33.3330
GANT-58 TYK-NU CTRP1 0.2604 33.3330
GANT-58 A-375 CTRP1 0.2604 33.3330
GANT-58 SK-MEL-1 CTRP1 0.2604 33.3330
GANT-58 SK-MEL-28 CTRP1 0.2604 33.3330
GANT-58 SK-MEL-5 CTRP1 0.2604 33.3330
GANT-58 HT-1080 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.