Drug : Pf-3845

CTRP1 Name : PF-3845

Dataset : All
Synonyms :
Targets : FAAH
Pathways : inhibitor of fatty acid amide hydrolase

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
PF-3845 U2OS CTRP1 0.2604 33.3330
PF-3845 MCF-7 CTRP1 0.2604 33.3330
PF-3845 GAMG CTRP1 0.2603 33.3330
PF-3845 LN-229 CTRP1 0.2604 33.3330
PF-3845 SF295 CTRP1 0.2603 33.3330
PF-3845 HEC-108 CTRP1 0.2603 33.3330
PF-3845 HEC-151 CTRP1 0.2604 33.3330
PF-3845 HEC-251 CTRP1 0.2603 33.3330
PF-3845 HEC-265 CTRP1 0.2603 33.3330
PF-3845 HEC-59 CTRP1 0.2603 33.3330
PF-3845 HEC-6 CTRP1 0.2603 33.3330
PF-3845 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
PF-3845 JHUEM-2 CTRP1 0.2604 33.3330
PF-3845 KLE CTRP1 0.2603 33.3330
PF-3845 MFE-319 CTRP1 0.2603 33.3330
PF-3845 SNG-M CTRP1 0.2603 33.3330
PF-3845 AMO1 CTRP1 0.2604 33.3330
PF-3845 BL-70 CTRP1 0.2603 33.3330
PF-3845 EJM CTRP1 0.2604 33.3330
PF-3845 GDM-1 CTRP1 0.2604 33.3330
PF-3845 HT CTRP1 0.2603 33.3330
PF-3845 KMS-11 CTRP1 0.2604 33.3330
PF-3845 KU812 CTRP1 0.2603 33.3330
PF-3845 LP-1 CTRP1 0.2604 33.3330
PF-3845 MC116 CTRP1 0.2603 33.3330
PF-3845 MOLM-16 CTRP1 0.2604 33.3330
PF-3845 NOMO-1 CTRP1 0.2604 33.3330
PF-3845 NU-DUL-1 CTRP1 0.2604 33.3330
PF-3845 OCI-AML-3 CTRP1 0.2604 33.3330
PF-3845 OCI-LY10 CTRP1 0.2604 33.3330
PF-3845 P3HR-1 CTRP1 0.2603 33.3330
PF-3845 PL21 CTRP1 0.2604 33.3330
PF-3845 RPMI-8226 CTRP1 0.2604 33.3330
PF-3845 SKM-1 CTRP1 0.2604 33.3330
PF-3845 SU-DHL-4 CTRP1 0.2604 33.3330
PF-3845 SU-DHL-5 CTRP1 0.2604 33.3330
PF-3845 THP-1 CTRP1 0.2604 33.3330
PF-3845 U-937 CTRP1 0.2604 33.3330
PF-3845 WSU-DLCL2 CTRP1 0.2604 33.3330
PF-3845 RCC10RGB CTRP1 0.2604 33.3330
PF-3845 VMRC-RCW CTRP1 0.2603 33.3330
PF-3845 C2BBE1 CTRP1 0.2603 33.3330
PF-3845 CL-34 CTRP1 0.2604 33.3330
PF-3845 CL-40 CTRP1 0.2604 33.3330
PF-3845 COLO205 CTRP1 0.2603 33.3330
PF-3845 COLO320 CTRP1 0.2604 16.6670
PF-3845 COLO678 CTRP1 0.2604 33.3330
PF-3845 CW-2 CTRP1 0.2604 33.3330
PF-3845 DLD-1 CTRP1 0.2603 33.3330
PF-3845 GP2D CTRP1 0.2603 33.3330
PF-3845 HCT116 CTRP1 0.2604 33.3330
PF-3845 HCT8 CTRP1 0.2604 33.3330
PF-3845 HT115 CTRP1 0.2604 33.3330
PF-3845 HT-29 CTRP1 0.2604 33.3330
PF-3845 HT-55 CTRP1 0.2604 33.3330
PF-3845 KM12 CTRP1 0.2604 33.3330
PF-3845 LOVO CTRP1 0.2604 33.3330
PF-3845 LS123 CTRP1 0.2604 33.3330
PF-3845 LS180 CTRP1 0.2604 33.3330
PF-3845 LS411N CTRP1 0.2603 33.3330
PF-3845 LS513 CTRP1 0.2603 33.3330
PF-3845 MDST8 CTRP1 0.2604 33.3330
PF-3845 NCI-H508 CTRP1 0.2604 33.3330
PF-3845 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
PF-3845 RKO CTRP1 0.2604 33.3330
PF-3845 SK-CO-1 CTRP1 0.2603 33.3330
PF-3845 SNU-1040 CTRP1 0.2604 33.3330
PF-3845 SNU-175 CTRP1 0.2604 33.3330
PF-3845 SNU-61 CTRP1 0.2604 33.3330
PF-3845 SNU-81 CTRP1 0.2604 33.3330
PF-3845 SNU-C2A CTRP1 0.2603 33.3330
PF-3845 SNU-C4 CTRP1 0.2604 33.3330
PF-3845 SNU-C5 CTRP1 0.2604 33.3330
PF-3845 SW403 CTRP1 0.2603 33.3330
PF-3845 SW48 CTRP1 0.2603 33.3330
PF-3845 SW480 CTRP1 0.2604 33.3330
PF-3845 SW620 CTRP1 0.2604 33.3330
PF-3845 SW948 CTRP1 0.2604 33.3330
PF-3845 HEP-G2 CTRP1 0.2604 33.3330
PF-3845 JHH-6 CTRP1 0.2603 33.3330
PF-3845 SNU-398 CTRP1 0.2604 33.3330
PF-3845 SNU-449 CTRP1 0.2603 33.3330
PF-3845 A-549 CTRP1 0.2603 33.3330
PF-3845 BEN CTRP1 0.2603 33.3330
PF-3845 CAL-12T CTRP1 0.2604 33.3330
PF-3845 CALU-3 CTRP1 0.2603 33.3330
PF-3845 CALU-6 CTRP1 0.2603 33.3330
PF-3845 CHAGO-K-1 CTRP1 0.2603 33.3330
PF-3845 COLO668 CTRP1 0.2603 33.3330
PF-3845 COLO699 CTRP1 0.2604 33.3330
PF-3845 COR-L23 CTRP1 0.2604 33.3330
PF-3845 COR-L279 CTRP1 0.2603 33.3330
PF-3845 COR-L51 CTRP1 0.2604 33.3330
PF-3845 COR-L88 CTRP1 0.2603 33.3330
PF-3845 DMS273 CTRP1 0.2603 33.3330
PF-3845 DV-90 CTRP1 0.2603 33.3330
PF-3845 EBC-1 CTRP1 0.2603 33.3330
PF-3845 EPLC-272H CTRP1 0.2603 33.3330
PF-3845 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
PF-3845 HCC1195 CTRP1 0.2604 33.3330
PF-3845 HCC1359 CTRP1 0.2604 33.3330
PF-3845 HCC15 CTRP1 0.2604 33.3330
PF-3845 HCC1833 CTRP1 0.2604 33.3330
PF-3845 HCC2108 CTRP1 0.2604 33.3330
PF-3845 HCC2935 CTRP1 0.2604 33.3330
PF-3845 HCC33 CTRP1 0.2603 33.3330
PF-3845 HCC4006 CTRP1 0.2604 33.3330
PF-3845 HCC44 CTRP1 0.2603 33.3330
PF-3845 HCC78 CTRP1 0.2603 33.3330
PF-3845 HCC827 CTRP1 0.2604 33.3330
PF-3845 KNS-62 CTRP1 0.2603 33.3330
PF-3845 LC-1-SQ-SF CTRP1 0.2603 33.3330
PF-3845 LCLC-103H CTRP1 0.2603 33.3330
PF-3845 LCLC-97TM1 CTRP1 0.2603 33.3330
PF-3845 LU-65 CTRP1 0.2603 33.3330
PF-3845 LU-99 CTRP1 0.2603 33.3330
PF-3845 LXF289 CTRP1 0.2603 33.3330
PF-3845 NCI-H1048 CTRP1 0.2603 33.3330
PF-3845 NCI-H1105 CTRP1 0.2604 33.3330
PF-3845 NCI-H1299 CTRP1 0.2603 33.3330
PF-3845 NCI-H1355 CTRP1 0.2603 33.3330
PF-3845 NCI-H1373 CTRP1 0.2603 33.3330
PF-3845 NCI-H1435 CTRP1 0.2603 33.3330
PF-3845 NCI-H1437 CTRP1 0.2603 33.3330
PF-3845 NCI-H1568 CTRP1 0.2603 33.3330
PF-3845 NCI-H1573 CTRP1 0.2603 33.3330
PF-3845 NCI-H1666 CTRP1 0.2603 33.3330
PF-3845 NCI-H1694 CTRP1 0.2604 33.3330
PF-3845 NCI-H1755 CTRP1 0.2604 33.3330
PF-3845 NCI-H1781 CTRP1 0.2604 33.3330
PF-3845 NCI-H1792 CTRP1 0.2603 33.3330
PF-3845 NCI-H1793 CTRP1 0.2603 33.3330
PF-3845 NCI-H1836 CTRP1 0.2604 33.3330
PF-3845 NCI-H1876 CTRP1 0.2604 33.3330
PF-3845 NCI-H1915 CTRP1 0.2603 33.3330
PF-3845 NCI-H1930 CTRP1 0.2603 33.3330
PF-3845 NCI-H1944 CTRP1 0.2603 33.3330
PF-3845 NCI-H1963 CTRP1 0.2604 33.3330
PF-3845 NCI-H1975 CTRP1 0.2603 33.3330
PF-3845 NCI-H2009 CTRP1 0.2603 33.3330
PF-3845 NCI-H2023 CTRP1 0.2604 33.3330
PF-3845 NCI-H2029 CTRP1 0.2603 33.3330
PF-3845 NCI-H2030 CTRP1 0.2604 33.3330
PF-3845 NCI-H2073 CTRP1 0.2604 33.3330
PF-3845 NCI-H2081 CTRP1 0.2604 33.3330
PF-3845 NCI-H2110 CTRP1 0.2604 33.3330
PF-3845 NCI-H2122 CTRP1 0.2604 33.3330
PF-3845 NCI-H2126 CTRP1 0.2603 33.3330
PF-3845 NCI-H2141 CTRP1 0.2604 33.3330
PF-3845 NCI-H2172 CTRP1 0.2604 33.3330
PF-3845 NCI-H2286 CTRP1 0.2603 33.3330
PF-3845 NCI-H23 CTRP1 0.2603 33.3330
PF-3845 NCI-H2342 CTRP1 0.2604 33.3330
PF-3845 NCI-H2405 CTRP1 0.2603 33.3330
PF-3845 NCI-H3255 CTRP1 0.2604 33.3330
PF-3845 NCI-H358 CTRP1 0.2603 33.3330
PF-3845 NCI-H441 CTRP1 0.2604 33.3330
PF-3845 NCI-H460 CTRP1 0.2604 33.3330
PF-3845 NCI-H522 CTRP1 0.2603 33.3330
PF-3845 NCI-H596 CTRP1 0.2604 33.3330
PF-3845 NCI-H650 CTRP1 0.2603 33.3330
PF-3845 NCI-H661 CTRP1 0.2603 33.3330
PF-3845 NCI-H727 CTRP1 0.2603 33.3330
PF-3845 NCI-H810 CTRP1 0.2603 33.3330
PF-3845 NCI-H82 CTRP1 0.2603 33.3330
PF-3845 NCI-H841 CTRP1 0.2604 33.3330
PF-3845 RERF-LC-KJ CTRP1 0.2603 33.3330
PF-3845 SCLC-21H CTRP1 0.2604 33.3330
PF-3845 SHP-77 CTRP1 0.2603 33.3330
PF-3845 SK-LU-1 CTRP1 0.2604 33.3330
PF-3845 SQ-1 CTRP1 0.2604 33.3330
PF-3845 T3M-10 CTRP1 0.2604 33.3330
PF-3845 VMRC-LCD CTRP1 0.2603 33.3330
PF-3845 KYSE-140 CTRP1 0.2603 33.3330
PF-3845 KYSE-410 CTRP1 0.2603 33.3330
PF-3845 KYSE-450 CTRP1 0.2603 33.3330
PF-3845 A2780 CTRP1 0.2604 33.3330
PF-3845 CAOV-3 CTRP1 0.2604 33.3330
PF-3845 COV318 CTRP1 0.2603 33.3330
PF-3845 COV362 CTRP1 0.2604 33.3330
PF-3845 COV434 CTRP1 0.2604 33.3330
PF-3845 COV644 CTRP1 0.2604 33.3330
PF-3845 EFO-21 CTRP1 0.2603 33.3330
PF-3845 EFO-27 CTRP1 0.2604 33.3330
PF-3845 HEYA8 CTRP1 0.2603 33.3330
PF-3845 IGROV-1 CTRP1 0.2604 33.3330
PF-3845 JHOC-5 CTRP1 0.2604 33.3330
PF-3845 JHOM-1 CTRP1 0.2604 33.3330
PF-3845 JHOS-4 CTRP1 0.2603 33.3330
PF-3845 OAW42 CTRP1 0.2604 33.3330
PF-3845 OV7 CTRP1 0.2604 33.3330
PF-3845 OV-90 CTRP1 0.2604 33.3330
PF-3845 OVCAR-4 CTRP1 0.2604 33.3330
PF-3845 OVCAR-8 CTRP1 0.2604 33.3330
PF-3845 OVK18 CTRP1 0.2604 33.3330
PF-3845 OVKATE CTRP1 0.2604 33.3330
PF-3845 OVMANA CTRP1 0.2603 33.3330
PF-3845 RKN CTRP1 0.2604 33.3330
PF-3845 RMG-I CTRP1 0.2604 33.3330
PF-3845 RMUG-S CTRP1 0.2604 33.3330
PF-3845 SK-OV-3 CTRP1 0.2603 33.3330
PF-3845 SNU-840 CTRP1 0.2604 33.3330
PF-3845 TYK-NU CTRP1 0.2604 33.3330
PF-3845 CAPAN-2 CTRP1 0.2603 33.3330
PF-3845 CFPAC-1 CTRP1 0.2603 33.3330
PF-3845 HPAC CTRP1 0.2603 33.3330
PF-3845 HUP-T4 CTRP1 0.2603 33.3330
PF-3845 KP-3 CTRP1 0.2603 33.3330
PF-3845 PANC03.27 CTRP1 0.2603 33.3330
PF-3845 PANC10.05 CTRP1 0.2603 33.3330
PF-3845 PATU8902 CTRP1 0.2603 33.3330
PF-3845 QGP-1 CTRP1 0.2603 33.3330
PF-3845 SUIT-2 CTRP1 0.2603 33.3330
PF-3845 MSTO-211H CTRP1 0.2603 33.3330
PF-3845 NCI-H2052 CTRP1 0.2603 33.3330
PF-3845 NCI-H28 CTRP1 0.2603 33.3330
PF-3845 MIAPACA-3 CTRP1 0.2603 33.3330
PF-3845 A-375 CTRP1 0.2604 33.3330
PF-3845 COLO741 CTRP1 0.2603 33.3330
PF-3845 G-361 CTRP1 0.2603 33.3330
PF-3845 HS852.T CTRP1 0.2603 33.3330
PF-3845 HS936.T CTRP1 0.2603 33.3330
PF-3845 HS944.T CTRP1 0.2603 33.3330
PF-3845 SK-MEL-1 CTRP1 0.2604 33.3330
PF-3845 SK-MEL-28 CTRP1 0.2604 33.3330
PF-3845 SK-MEL-5 CTRP1 0.2604 33.3330
PF-3845 G-401 CTRP1 0.2603 33.3330
PF-3845 HT-1080 CTRP1 0.2604 33.3330
PF-3845 AGS CTRP1 0.2604 33.3330
PF-3845 FU97 CTRP1 0.2603 33.3330
PF-3845 KE-97 CTRP1 0.2603 33.3330
PF-3845 MKN7 CTRP1 0.2603 33.3330
PF-3845 MKN74 CTRP1 0.2603 33.3330
PF-3845 NUGC-4 CTRP1 0.2603 33.3330
PF-3845 SH-10-TC CTRP1 0.2603 33.3330
PF-3845 HSC-2 CTRP1 0.2603 33.3330
PF-3845 SCC-9 CTRP1 0.2604 33.3330
PF-3845 5637 CTRP1 0.2603 33.3330
PF-3845 HT-1376 CTRP1 0.2603 33.3330
PF-3845 KMBC-2 CTRP1 0.2603 33.3330
PF-3845 RT-4 CTRP1 0.2603 33.3330
PF-3845 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.