Drug : 3-Aminobenzamide

CTRP1 Name : 3-aminobenzamide

Dataset : All
Synonyms :
Targets : PARP1
Pathways : inhibitor of poly (ADP-ribose) polymerase 1

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
3-aminobenzamide LN-229 CTRP1 0.9564 122.4100
3-aminobenzamide JHUEM-2 CTRP1 0.9564 122.4100
3-aminobenzamide GDM-1 CTRP1 0.9564 122.4100
3-aminobenzamide MOLM-16 CTRP1 0.9564 122.4100
3-aminobenzamide NOMO-1 CTRP1 0.9564 122.4100
3-aminobenzamide NU-DUL-1 CTRP1 0.9564 122.4100
3-aminobenzamide OCI-AML-3 CTRP1 0.9564 122.4100
3-aminobenzamide PL21 CTRP1 0.9564 122.4100
3-aminobenzamide RPMI-8226 CTRP1 0.9564 122.4100
3-aminobenzamide SKM-1 CTRP1 0.9564 122.4100
3-aminobenzamide SU-DHL-4 CTRP1 0.9564 122.4100
3-aminobenzamide SU-DHL-5 CTRP1 0.9564 122.4100
3-aminobenzamide THP-1 CTRP1 0.9564 122.4100
3-aminobenzamide U-937 CTRP1 0.9564 122.4100
3-aminobenzamide WSU-DLCL2 CTRP1 0.9564 122.4100
3-aminobenzamide CL-34 CTRP1 0.9564 122.4100
3-aminobenzamide CL-40 CTRP1 0.9564 122.4100
3-aminobenzamide COLO678 CTRP1 0.9564 122.4100
3-aminobenzamide HCT116 CTRP1 0.9564 122.4100
3-aminobenzamide HCT8 CTRP1 0.9564 122.4100
3-aminobenzamide HT115 CTRP1 0.9564 122.4100
3-aminobenzamide HT-29 CTRP1 0.9564 122.4100
3-aminobenzamide HT-55 CTRP1 0.9564 122.4100
3-aminobenzamide LOVO CTRP1 0.9564 122.4100
3-aminobenzamide LS123 CTRP1 0.9564 122.4100
3-aminobenzamide MDST8 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H508 CTRP1 0.9564 122.4100
3-aminobenzamide RCM-1[HUMANESC] CTRP1 0.9564 122.4100
3-aminobenzamide RKO CTRP1 0.9564 122.4100
3-aminobenzamide SNU-1040 CTRP1 0.9564 122.4100
3-aminobenzamide SW480 CTRP1 0.9564 122.4100
3-aminobenzamide SW620 CTRP1 0.9564 122.4100
3-aminobenzamide HCC15 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H1755 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H1781 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H2122 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H441 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H460 CTRP1 0.9564 122.4100
3-aminobenzamide NCI-H596 CTRP1 0.9564 122.4100
3-aminobenzamide SK-LU-1 CTRP1 0.9564 122.4100
3-aminobenzamide T3M-10 CTRP1 0.9564 122.4100
3-aminobenzamide CAOV-3 CTRP1 0.9564 122.4100
3-aminobenzamide COV644 CTRP1 0.9564 122.4100
3-aminobenzamide OV7 CTRP1 0.9564 122.4100
3-aminobenzamide OV-90 CTRP1 0.9564 122.4100
3-aminobenzamide RMUG-S CTRP1 0.9564 122.4100
3-aminobenzamide SNU-840 CTRP1 0.9564 122.4100
3-aminobenzamide TYK-NU CTRP1 0.9564 122.4100
3-aminobenzamide A-375 CTRP1 0.9564 122.4100
3-aminobenzamide SK-MEL-1 CTRP1 0.9564 122.4100
3-aminobenzamide SK-MEL-28 CTRP1 0.9564 122.4100
3-aminobenzamide SK-MEL-5 CTRP1 0.9564 122.4100
3-aminobenzamide HT-1080 CTRP1 0.9564 122.4100

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.