Drug : Ml100

CTRP1 Name : ML100

Dataset : All
Synonyms :
Targets :
Pathways : potentiates TRAIL-induced apoptosis of cancer cells

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
ML100 MCF-7 CTRP1 0.2604 33.3330
ML100 GAMG CTRP1 0.2603 33.3330
ML100 LN-229 CTRP1 0.2604 33.3330
ML100 HEC-108 CTRP1 0.2603 33.3330
ML100 HEC-151 CTRP1 0.1302 33.3330
ML100 HEC-59 CTRP1 0.2603 33.3330
ML100 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
ML100 JHUEM-2 CTRP1 0.2604 33.3330
ML100 KLE CTRP1 0.2603 33.3330
ML100 SNG-M CTRP1 0.2603 33.3330
ML100 AMO1 CTRP1 0.1302 33.3330
ML100 BL-70 CTRP1 0.2603 33.3330
ML100 EJM CTRP1 0.2604 33.3330
ML100 GDM-1 CTRP1 0.2604 33.3330
ML100 KMS-11 CTRP1 0.1302 33.3330
ML100 LP-1 CTRP1 0.1302 33.3330
ML100 MOLM-16 CTRP1 0.2604 33.3330
ML100 NOMO-1 CTRP1 0.2604 33.3330
ML100 NU-DUL-1 CTRP1 0.2604 33.3330
ML100 OCI-AML-3 CTRP1 0.2604 33.3330
ML100 OCI-LY10 CTRP1 0.1302 33.3330
ML100 PL21 CTRP1 0.2604 33.3330
ML100 RPMI-8226 CTRP1 0.2604 33.3330
ML100 SKM-1 CTRP1 0.2604 33.3330
ML100 SU-DHL-4 CTRP1 0.2604 33.3330
ML100 SU-DHL-5 CTRP1 0.2604 33.3330
ML100 THP-1 CTRP1 0.2604 33.3330
ML100 U-937 CTRP1 0.2604 33.3330
ML100 WSU-DLCL2 CTRP1 0.2604 33.3330
ML100 CL-34 CTRP1 0.2604 33.3330
ML100 CL-40 CTRP1 0.2604 33.3330
ML100 COLO320 CTRP1 0.2604 33.3330
ML100 COLO678 CTRP1 0.2604 33.3330
ML100 CW-2 CTRP1 0.2604 33.3330
ML100 HCT116 CTRP1 0.2604 33.3330
ML100 HCT8 CTRP1 0.2604 33.3330
ML100 HT115 CTRP1 0.2604 33.3330
ML100 HT-29 CTRP1 0.2604 33.3330
ML100 HT-55 CTRP1 0.2604 33.3330
ML100 KM12 CTRP1 0.2604 33.3330
ML100 LOVO CTRP1 0.2604 33.3330
ML100 LS123 CTRP1 0.2604 33.3330
ML100 LS180 CTRP1 0.1302 33.3330
ML100 MDST8 CTRP1 0.2604 33.3330
ML100 NCI-H508 CTRP1 0.2604 33.3330
ML100 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
ML100 RKO CTRP1 0.2604 33.3330
ML100 SNU-1040 CTRP1 0.2604 33.3330
ML100 SNU-175 CTRP1 0.2604 33.3330
ML100 SNU-61 CTRP1 0.2604 33.3330
ML100 SNU-81 CTRP1 0.2604 33.3330
ML100 SNU-C4 CTRP1 0.2604 33.3330
ML100 SNU-C5 CTRP1 0.2604 33.3330
ML100 SW480 CTRP1 0.2604 33.3330
ML100 SW620 CTRP1 0.2604 33.3330
ML100 SW948 CTRP1 0.2604 33.3330
ML100 HEP-G2 CTRP1 0.2604 33.3330
ML100 JHH-6 CTRP1 0.2603 33.3330
ML100 SNU-398 CTRP1 0.1302 33.3330
ML100 SNU-449 CTRP1 0.2603 33.3330
ML100 CAL-12T CTRP1 0.2604 33.3330
ML100 COLO668 CTRP1 0.2603 33.3330
ML100 COLO699 CTRP1 0.2604 33.3330
ML100 COR-L23 CTRP1 0.2604 33.3330
ML100 COR-L51 CTRP1 0.1302 33.3330
ML100 HCC1195 CTRP1 0.2604 33.3330
ML100 HCC1359 CTRP1 0.2604 33.3330
ML100 HCC15 CTRP1 0.2604 33.3330
ML100 HCC1833 CTRP1 0.2604 33.3330
ML100 HCC2108 CTRP1 0.2604 33.3330
ML100 HCC2935 CTRP1 0.2604 33.3330
ML100 HCC4006 CTRP1 0.2604 33.3330
ML100 HCC827 CTRP1 0.2604 33.3330
ML100 LXF289 CTRP1 0.2603 33.3330
ML100 NCI-H1105 CTRP1 0.2604 33.3330
ML100 NCI-H1435 CTRP1 0.2603 33.3330
ML100 NCI-H1694 CTRP1 0.2604 33.3330
ML100 NCI-H1755 CTRP1 0.2604 33.3330
ML100 NCI-H1781 CTRP1 0.2604 33.3330
ML100 NCI-H1836 CTRP1 0.2604 33.3330
ML100 NCI-H1876 CTRP1 0.2604 33.3330
ML100 NCI-H1915 CTRP1 0.2603 33.3330
ML100 NCI-H1930 CTRP1 0.2603 33.3330
ML100 NCI-H1963 CTRP1 0.1302 33.3330
ML100 NCI-H2023 CTRP1 0.2604 33.3330
ML100 NCI-H2030 CTRP1 0.2604 33.3330
ML100 NCI-H2073 CTRP1 0.2604 33.3330
ML100 NCI-H2081 CTRP1 0.2604 33.3330
ML100 NCI-H2110 CTRP1 0.2604 33.3330
ML100 NCI-H2122 CTRP1 0.2604 33.3330
ML100 NCI-H2141 CTRP1 0.1302 33.3330
ML100 NCI-H2172 CTRP1 0.2604 33.3330
ML100 NCI-H2286 CTRP1 0.2603 33.3330
ML100 NCI-H2342 CTRP1 0.2604 33.3330
ML100 NCI-H3255 CTRP1 0.2604 33.3330
ML100 NCI-H441 CTRP1 0.2604 33.3330
ML100 NCI-H460 CTRP1 0.2604 33.3330
ML100 NCI-H596 CTRP1 0.2604 33.3330
ML100 NCI-H841 CTRP1 0.2604 33.3330
ML100 RERF-LC-KJ CTRP1 0.2603 33.3330
ML100 SCLC-21H CTRP1 0.1302 33.3330
ML100 SK-LU-1 CTRP1 0.2604 33.3330
ML100 SQ-1 CTRP1 0.2604 33.3330
ML100 T3M-10 CTRP1 0.2604 33.3330
ML100 A2780 CTRP1 0.1302 33.3330
ML100 CAOV-3 CTRP1 0.2604 33.3330
ML100 COV318 CTRP1 0.2603 33.3330
ML100 COV362 CTRP1 0.2604 33.3330
ML100 COV434 CTRP1 0.2604 33.3330
ML100 COV644 CTRP1 0.2604 33.3330
ML100 EFO-27 CTRP1 0.2604 33.3330
ML100 IGROV-1 CTRP1 0.1302 33.3330
ML100 JHOC-5 CTRP1 0.2604 33.3330
ML100 JHOM-1 CTRP1 0.2604 33.3330
ML100 JHOS-4 CTRP1 0.2603 33.3330
ML100 OAW42 CTRP1 0.2604 33.3330
ML100 OV7 CTRP1 0.2604 33.3330
ML100 OV-90 CTRP1 0.2604 33.3330
ML100 OVCAR-4 CTRP1 0.1302 33.3330
ML100 OVCAR-8 CTRP1 0.1302 33.3330
ML100 OVK18 CTRP1 0.2604 33.3330
ML100 OVKATE CTRP1 0.1302 33.3330
ML100 OVMANA CTRP1 0.2603 33.3330
ML100 RKN CTRP1 0.1302 33.3330
ML100 RMG-I CTRP1 0.2604 33.3330
ML100 RMUG-S CTRP1 0.2604 33.3330
ML100 SNU-840 CTRP1 0.2604 33.3330
ML100 TYK-NU CTRP1 0.2604 33.3330
ML100 PATU8902 CTRP1 0.2603 33.3330
ML100 MIAPACA-3 CTRP1 0.2603 33.3330
ML100 A-375 CTRP1 0.2604 33.3330
ML100 HS852.T CTRP1 0.2603 33.3330
ML100 SK-MEL-1 CTRP1 0.2604 33.3330
ML100 SK-MEL-28 CTRP1 0.2604 33.3330
ML100 SK-MEL-5 CTRP1 0.2604 33.3330
ML100 HT-1080 CTRP1 0.2604 33.3330
ML100 AGS CTRP1 0.1302 33.3330
ML100 MKN74 CTRP1 0.2603 33.3330
ML100 SCC-9 CTRP1 0.1302 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.