Drug : Compound 110

CTRP1 Name : Compound 110

Dataset : All
Synonyms :
Targets : PIK3CA
Pathways : inhibitor of PI3K p110?

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
Compound 110 U2OS CTRP1 0.5781 74.0000
Compound 110 MCF-7 CTRP1 0.5781 74.0000
Compound 110 GAMG CTRP1 0.2890 37.0000
Compound 110 LN-229 CTRP1 0.5781 74.0000
Compound 110 SF295 CTRP1 0.2890 37.0000
Compound 110 HEC-108 CTRP1 0.2890 37.0000
Compound 110 HEC-151 CTRP1 0.5781 74.0000
Compound 110 HEC-251 CTRP1 0.2890 37.0000
Compound 110 HEC-265 CTRP1 0.2890 37.0000
Compound 110 HEC-59 CTRP1 0.2890 37.0000
Compound 110 HEC-6 CTRP1 0.2890 37.0000
Compound 110 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2890 37.0000
Compound 110 JHUEM-2 CTRP1 0.5781 74.0000
Compound 110 KLE CTRP1 0.2890 37.0000
Compound 110 MFE-319 CTRP1 0.2890 37.0000
Compound 110 SNG-M CTRP1 0.2890 37.0000
Compound 110 AMO1 CTRP1 0.5781 74.0000
Compound 110 BL-70 CTRP1 0.2890 37.0000
Compound 110 EJM CTRP1 0.5781 74.0000
Compound 110 GDM-1 CTRP1 0.5781 74.0000
Compound 110 HT CTRP1 0.2890 37.0000
Compound 110 KMS-11 CTRP1 0.5781 74.0000
Compound 110 KU812 CTRP1 0.2890 37.0000
Compound 110 LP-1 CTRP1 0.5781 74.0000
Compound 110 MC116 CTRP1 0.2890 37.0000
Compound 110 MOLM-16 CTRP1 0.5781 74.0000
Compound 110 NOMO-1 CTRP1 0.5781 74.0000
Compound 110 NU-DUL-1 CTRP1 0.5781 74.0000
Compound 110 OCI-AML-3 CTRP1 0.5781 74.0000
Compound 110 OCI-LY10 CTRP1 0.5781 74.0000
Compound 110 P3HR-1 CTRP1 0.2890 37.0000
Compound 110 PL21 CTRP1 0.5781 74.0000
Compound 110 RPMI-8226 CTRP1 0.5781 74.0000
Compound 110 SKM-1 CTRP1 0.5781 74.0000
Compound 110 SU-DHL-4 CTRP1 0.5781 74.0000
Compound 110 SU-DHL-5 CTRP1 0.5781 74.0000
Compound 110 THP-1 CTRP1 0.5781 74.0000
Compound 110 U-937 CTRP1 0.5781 74.0000
Compound 110 WSU-DLCL2 CTRP1 0.5781 74.0000
Compound 110 RCC10RGB CTRP1 0.5781 74.0000
Compound 110 VMRC-RCW CTRP1 0.2890 37.0000
Compound 110 C2BBE1 CTRP1 0.2890 37.0000
Compound 110 CL-34 CTRP1 0.5781 74.0000
Compound 110 CL-40 CTRP1 0.5781 74.0000
Compound 110 COLO205 CTRP1 0.2890 37.0000
Compound 110 COLO320 CTRP1 0.5781 74.0000
Compound 110 COLO678 CTRP1 0.5781 74.0000
Compound 110 CW-2 CTRP1 0.5781 74.0000
Compound 110 DLD-1 CTRP1 0.2890 37.0000
Compound 110 GP2D CTRP1 0.2890 37.0000
Compound 110 HCT116 CTRP1 0.5781 74.0000
Compound 110 HCT8 CTRP1 0.5781 74.0000
Compound 110 HT115 CTRP1 0.5781 74.0000
Compound 110 HT-29 CTRP1 0.5781 74.0000
Compound 110 HT-55 CTRP1 0.5781 74.0000
Compound 110 KM12 CTRP1 0.5781 74.0000
Compound 110 LOVO CTRP1 0.5781 74.0000
Compound 110 LS123 CTRP1 0.5781 74.0000
Compound 110 LS180 CTRP1 0.5781 74.0000
Compound 110 LS411N CTRP1 0.2890 37.0000
Compound 110 LS513 CTRP1 0.2890 37.0000
Compound 110 MDST8 CTRP1 0.5781 74.0000
Compound 110 NCI-H508 CTRP1 0.5781 74.0000
Compound 110 RCM-1[HUMANESC] CTRP1 0.5781 74.0000
Compound 110 RKO CTRP1 0.5781 74.0000
Compound 110 SK-CO-1 CTRP1 0.2890 37.0000
Compound 110 SNU-1040 CTRP1 0.5781 74.0000
Compound 110 SNU-175 CTRP1 0.5781 74.0000
Compound 110 SNU-61 CTRP1 0.5781 74.0000
Compound 110 SNU-81 CTRP1 0.5781 74.0000
Compound 110 SNU-C2A CTRP1 0.2890 37.0000
Compound 110 SNU-C4 CTRP1 0.5781 74.0000
Compound 110 SNU-C5 CTRP1 0.5781 74.0000
Compound 110 SW403 CTRP1 0.2890 37.0000
Compound 110 SW48 CTRP1 0.2890 37.0000
Compound 110 SW480 CTRP1 0.5781 74.0000
Compound 110 SW620 CTRP1 0.5781 74.0000
Compound 110 SW948 CTRP1 0.5781 74.0000
Compound 110 HEP-G2 CTRP1 0.5781 74.0000
Compound 110 JHH-6 CTRP1 0.2890 37.0000
Compound 110 SNU-398 CTRP1 0.5781 74.0000
Compound 110 SNU-449 CTRP1 0.2890 37.0000
Compound 110 A-549 CTRP1 0.2890 37.0000
Compound 110 BEN CTRP1 0.2890 37.0000
Compound 110 CAL-12T CTRP1 0.5781 74.0000
Compound 110 CALU-3 CTRP1 0.2890 37.0000
Compound 110 CALU-6 CTRP1 0.2890 37.0000
Compound 110 CHAGO-K-1 CTRP1 0.2890 37.0000
Compound 110 COLO668 CTRP1 0.2890 37.0000
Compound 110 COLO699 CTRP1 0.5781 74.0000
Compound 110 COR-L23 CTRP1 0.5781 74.0000
Compound 110 COR-L279 CTRP1 0.2890 37.0000
Compound 110 COR-L51 CTRP1 0.5781 74.0000
Compound 110 COR-L88 CTRP1 0.2890 37.0000
Compound 110 DMS273 CTRP1 0.2890 37.0000
Compound 110 DV-90 CTRP1 0.2890 37.0000
Compound 110 EBC-1 CTRP1 0.2890 37.0000
Compound 110 EPLC-272H CTRP1 0.2890 37.0000
Compound 110 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2890 37.0000
Compound 110 HCC1195 CTRP1 0.5781 74.0000
Compound 110 HCC1359 CTRP1 0.5781 74.0000
Compound 110 HCC15 CTRP1 0.5781 74.0000
Compound 110 HCC1833 CTRP1 0.5781 74.0000
Compound 110 HCC2108 CTRP1 0.5781 74.0000
Compound 110 HCC2935 CTRP1 0.5781 74.0000
Compound 110 HCC33 CTRP1 0.2890 37.0000
Compound 110 HCC4006 CTRP1 0.5781 74.0000
Compound 110 HCC44 CTRP1 0.2890 37.0000
Compound 110 HCC78 CTRP1 0.2890 37.0000
Compound 110 HCC827 CTRP1 0.5781 74.0000
Compound 110 KNS-62 CTRP1 0.2890 37.0000
Compound 110 LC-1-SQ-SF CTRP1 0.2890 37.0000
Compound 110 LCLC-103H CTRP1 0.2890 37.0000
Compound 110 LCLC-97TM1 CTRP1 0.2890 37.0000
Compound 110 LU-65 CTRP1 0.2890 37.0000
Compound 110 LU-99 CTRP1 0.2890 37.0000
Compound 110 LXF289 CTRP1 0.2890 37.0000
Compound 110 NCI-H1048 CTRP1 0.2890 37.0000
Compound 110 NCI-H1105 CTRP1 0.5781 74.0000
Compound 110 NCI-H1299 CTRP1 0.2890 37.0000
Compound 110 NCI-H1355 CTRP1 0.2890 37.0000
Compound 110 NCI-H1373 CTRP1 0.2890 37.0000
Compound 110 NCI-H1435 CTRP1 0.2890 37.0000
Compound 110 NCI-H1437 CTRP1 0.2890 37.0000
Compound 110 NCI-H1568 CTRP1 0.2890 37.0000
Compound 110 NCI-H1573 CTRP1 0.2890 37.0000
Compound 110 NCI-H1666 CTRP1 0.2890 37.0000
Compound 110 NCI-H1694 CTRP1 0.5781 74.0000
Compound 110 NCI-H1755 CTRP1 0.5781 74.0000
Compound 110 NCI-H1781 CTRP1 0.5781 74.0000
Compound 110 NCI-H1792 CTRP1 0.2890 37.0000
Compound 110 NCI-H1793 CTRP1 0.2890 37.0000
Compound 110 NCI-H1836 CTRP1 0.5781 74.0000
Compound 110 NCI-H1876 CTRP1 0.5781 74.0000
Compound 110 NCI-H1915 CTRP1 0.2890 37.0000
Compound 110 NCI-H1930 CTRP1 0.2890 37.0000
Compound 110 NCI-H1944 CTRP1 0.2890 37.0000
Compound 110 NCI-H1963 CTRP1 0.5781 74.0000
Compound 110 NCI-H1975 CTRP1 0.2890 37.0000
Compound 110 NCI-H2009 CTRP1 0.2890 37.0000
Compound 110 NCI-H2023 CTRP1 0.5781 74.0000
Compound 110 NCI-H2029 CTRP1 0.2890 37.0000
Compound 110 NCI-H2030 CTRP1 0.5781 74.0000
Compound 110 NCI-H2073 CTRP1 0.5781 74.0000
Compound 110 NCI-H2081 CTRP1 0.5781 74.0000
Compound 110 NCI-H2110 CTRP1 0.5781 74.0000
Compound 110 NCI-H2122 CTRP1 0.5781 74.0000
Compound 110 NCI-H2126 CTRP1 0.2890 37.0000
Compound 110 NCI-H2141 CTRP1 0.5781 74.0000
Compound 110 NCI-H2172 CTRP1 0.5781 74.0000
Compound 110 NCI-H2286 CTRP1 0.2890 37.0000
Compound 110 NCI-H23 CTRP1 0.2890 37.0000
Compound 110 NCI-H2342 CTRP1 0.5781 74.0000
Compound 110 NCI-H2405 CTRP1 0.2890 37.0000
Compound 110 NCI-H3255 CTRP1 0.5781 74.0000
Compound 110 NCI-H358 CTRP1 0.2890 37.0000
Compound 110 NCI-H441 CTRP1 0.5781 74.0000
Compound 110 NCI-H460 CTRP1 0.5781 74.0000
Compound 110 NCI-H522 CTRP1 0.2890 37.0000
Compound 110 NCI-H596 CTRP1 0.5781 74.0000
Compound 110 NCI-H650 CTRP1 0.2890 37.0000
Compound 110 NCI-H661 CTRP1 0.2890 37.0000
Compound 110 NCI-H727 CTRP1 0.2890 37.0000
Compound 110 NCI-H810 CTRP1 0.2890 37.0000
Compound 110 NCI-H82 CTRP1 0.2890 37.0000
Compound 110 NCI-H841 CTRP1 0.5781 74.0000
Compound 110 RERF-LC-KJ CTRP1 0.2890 37.0000
Compound 110 SCLC-21H CTRP1 0.5781 74.0000
Compound 110 SHP-77 CTRP1 0.2890 37.0000
Compound 110 SK-LU-1 CTRP1 0.5781 74.0000
Compound 110 SQ-1 CTRP1 0.5781 74.0000
Compound 110 T3M-10 CTRP1 0.5781 74.0000
Compound 110 VMRC-LCD CTRP1 0.2890 37.0000
Compound 110 KYSE-140 CTRP1 0.2890 37.0000
Compound 110 KYSE-410 CTRP1 0.2890 37.0000
Compound 110 KYSE-450 CTRP1 0.2890 37.0000
Compound 110 A2780 CTRP1 0.5781 74.0000
Compound 110 CAOV-3 CTRP1 0.5781 74.0000
Compound 110 COV318 CTRP1 0.2890 37.0000
Compound 110 COV362 CTRP1 0.5781 74.0000
Compound 110 COV434 CTRP1 0.5781 74.0000
Compound 110 COV644 CTRP1 0.5781 74.0000
Compound 110 EFO-21 CTRP1 0.2890 37.0000
Compound 110 EFO-27 CTRP1 0.5781 74.0000
Compound 110 HEYA8 CTRP1 0.2890 37.0000
Compound 110 IGROV-1 CTRP1 0.5781 74.0000
Compound 110 JHOC-5 CTRP1 0.5781 74.0000
Compound 110 JHOM-1 CTRP1 0.5781 74.0000
Compound 110 JHOS-4 CTRP1 0.2890 37.0000
Compound 110 OAW42 CTRP1 0.5781 74.0000
Compound 110 OV7 CTRP1 0.5781 74.0000
Compound 110 OV-90 CTRP1 0.5781 74.0000
Compound 110 OVCAR-4 CTRP1 0.5781 74.0000
Compound 110 OVCAR-8 CTRP1 0.5781 74.0000
Compound 110 OVK18 CTRP1 0.5781 74.0000
Compound 110 OVKATE CTRP1 0.5781 74.0000
Compound 110 OVMANA CTRP1 0.2890 37.0000
Compound 110 RKN CTRP1 0.5781 74.0000
Compound 110 RMG-I CTRP1 0.5781 74.0000
Compound 110 RMUG-S CTRP1 0.5781 74.0000
Compound 110 SK-OV-3 CTRP1 0.2890 37.0000
Compound 110 SNU-840 CTRP1 0.5781 74.0000
Compound 110 TYK-NU CTRP1 0.5781 74.0000
Compound 110 CAPAN-2 CTRP1 0.2890 37.0000
Compound 110 CFPAC-1 CTRP1 0.2890 37.0000
Compound 110 HPAC CTRP1 0.2890 37.0000
Compound 110 HUP-T4 CTRP1 0.2890 37.0000
Compound 110 KP-3 CTRP1 0.2890 37.0000
Compound 110 PANC03.27 CTRP1 0.2890 37.0000
Compound 110 PANC10.05 CTRP1 0.2890 37.0000
Compound 110 PATU8902 CTRP1 0.2890 37.0000
Compound 110 QGP-1 CTRP1 0.2890 37.0000
Compound 110 SUIT-2 CTRP1 0.2890 37.0000
Compound 110 MSTO-211H CTRP1 0.2890 37.0000
Compound 110 NCI-H2052 CTRP1 0.2890 37.0000
Compound 110 NCI-H28 CTRP1 0.2890 37.0000
Compound 110 MIAPACA-3 CTRP1 0.2890 37.0000
Compound 110 A-375 CTRP1 0.5781 74.0000
Compound 110 COLO741 CTRP1 0.2890 37.0000
Compound 110 G-361 CTRP1 0.2890 37.0000
Compound 110 HS852.T CTRP1 0.2890 37.0000
Compound 110 HS936.T CTRP1 0.2890 37.0000
Compound 110 HS944.T CTRP1 0.2890 37.0000
Compound 110 SK-MEL-1 CTRP1 0.5781 74.0000
Compound 110 SK-MEL-28 CTRP1 0.5781 74.0000
Compound 110 SK-MEL-5 CTRP1 0.5781 74.0000
Compound 110 G-401 CTRP1 0.2890 37.0000
Compound 110 HT-1080 CTRP1 0.5781 74.0000
Compound 110 AGS CTRP1 0.5781 74.0000
Compound 110 FU97 CTRP1 0.2890 37.0000
Compound 110 KE-97 CTRP1 0.2890 37.0000
Compound 110 MKN7 CTRP1 0.2890 37.0000
Compound 110 MKN74 CTRP1 0.2890 37.0000
Compound 110 NUGC-4 CTRP1 0.2890 37.0000
Compound 110 SH-10-TC CTRP1 0.2890 37.0000
Compound 110 HSC-2 CTRP1 0.2890 37.0000
Compound 110 SCC-9 CTRP1 0.5781 74.0000
Compound 110 5637 CTRP1 0.2890 37.0000
Compound 110 HT-1376 CTRP1 0.2890 37.0000
Compound 110 KMBC-2 CTRP1 0.2890 37.0000
Compound 110 RT-4 CTRP1 0.2890 37.0000
Compound 110 UM-UC-3 CTRP1 0.2890 37.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.