Drug : Ml214

CTRP1 Name : ML214

Dataset : All
Synonyms :
Targets :
Pathways : promotes A1-dependent apoptosis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
ML214 MCF-7 CTRP1 0.2604 33.3330
ML214 LN-229 CTRP1 0.2604 33.3330
ML214 JHUEM-2 CTRP1 0.2604 33.3330
ML214 EJM CTRP1 0.2604 33.3330
ML214 GDM-1 CTRP1 0.2604 33.3330
ML214 MOLM-16 CTRP1 0.2604 33.3330
ML214 NOMO-1 CTRP1 0.2604 33.3330
ML214 NU-DUL-1 CTRP1 0.2604 33.3330
ML214 OCI-AML-3 CTRP1 0.2604 33.3330
ML214 PL21 CTRP1 0.2604 33.3330
ML214 RPMI-8226 CTRP1 0.2604 33.3330
ML214 SKM-1 CTRP1 0.2604 33.3330
ML214 SU-DHL-4 CTRP1 0.2604 33.3330
ML214 SU-DHL-5 CTRP1 0.2604 33.3330
ML214 THP-1 CTRP1 0.2604 33.3330
ML214 U-937 CTRP1 0.2604 33.3330
ML214 WSU-DLCL2 CTRP1 0.2604 33.3330
ML214 CL-34 CTRP1 0.2604 33.3330
ML214 CL-40 CTRP1 0.2604 33.3330
ML214 COLO320 CTRP1 0.2604 33.3330
ML214 COLO678 CTRP1 0.2604 33.3330
ML214 CW-2 CTRP1 0.2604 33.3330
ML214 HCT116 CTRP1 0.2604 33.3330
ML214 HCT8 CTRP1 0.2604 33.3330
ML214 HT115 CTRP1 0.2604 33.3330
ML214 HT-29 CTRP1 0.2604 33.3330
ML214 HT-55 CTRP1 0.2604 33.3330
ML214 KM12 CTRP1 0.2604 33.3330
ML214 LOVO CTRP1 0.2604 33.3330
ML214 LS123 CTRP1 0.2604 33.3330
ML214 MDST8 CTRP1 0.2604 33.3330
ML214 NCI-H508 CTRP1 0.2604 33.3330
ML214 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
ML214 RKO CTRP1 0.2604 33.3330
ML214 SNU-1040 CTRP1 0.2604 33.3330
ML214 SNU-175 CTRP1 0.2604 33.3330
ML214 SNU-61 CTRP1 0.2604 33.3330
ML214 SNU-81 CTRP1 0.2604 33.3330
ML214 SNU-C4 CTRP1 0.2604 33.3330
ML214 SNU-C5 CTRP1 0.2604 33.3330
ML214 SW480 CTRP1 0.2604 33.3330
ML214 SW620 CTRP1 0.2604 33.3330
ML214 SW948 CTRP1 0.2604 33.3330
ML214 HEP-G2 CTRP1 0.2604 33.3330
ML214 CAL-12T CTRP1 0.2604 33.3330
ML214 COLO699 CTRP1 0.2604 33.3330
ML214 COR-L23 CTRP1 0.2604 33.3330
ML214 HCC1195 CTRP1 0.2604 33.3330
ML214 HCC1359 CTRP1 0.2604 33.3330
ML214 HCC15 CTRP1 0.2604 33.3330
ML214 HCC1833 CTRP1 0.2604 33.3330
ML214 HCC2108 CTRP1 0.2604 33.3330
ML214 HCC2935 CTRP1 0.2604 33.3330
ML214 HCC4006 CTRP1 0.2604 33.3330
ML214 HCC827 CTRP1 0.2604 33.3330
ML214 NCI-H1105 CTRP1 0.2604 33.3330
ML214 NCI-H1694 CTRP1 0.2604 33.3330
ML214 NCI-H1755 CTRP1 0.2604 33.3330
ML214 NCI-H1781 CTRP1 0.2604 33.3330
ML214 NCI-H1836 CTRP1 0.2604 33.3330
ML214 NCI-H1876 CTRP1 0.2604 33.3330
ML214 NCI-H2023 CTRP1 0.2604 33.3330
ML214 NCI-H2030 CTRP1 0.2604 33.3330
ML214 NCI-H2073 CTRP1 0.2604 33.3330
ML214 NCI-H2081 CTRP1 0.2604 33.3330
ML214 NCI-H2110 CTRP1 0.2604 33.3330
ML214 NCI-H2122 CTRP1 0.2604 33.3330
ML214 NCI-H2172 CTRP1 0.2604 33.3330
ML214 NCI-H2342 CTRP1 0.2604 33.3330
ML214 NCI-H3255 CTRP1 0.2604 33.3330
ML214 NCI-H441 CTRP1 0.2604 33.3330
ML214 NCI-H460 CTRP1 0.2604 33.3330
ML214 NCI-H596 CTRP1 0.2604 33.3330
ML214 NCI-H841 CTRP1 0.2604 33.3330
ML214 SK-LU-1 CTRP1 0.2604 33.3330
ML214 SQ-1 CTRP1 0.2604 33.3330
ML214 T3M-10 CTRP1 0.2604 33.3330
ML214 CAOV-3 CTRP1 0.2604 33.3330
ML214 COV362 CTRP1 0.2604 33.3330
ML214 COV434 CTRP1 0.2604 33.3330
ML214 COV644 CTRP1 0.2604 33.3330
ML214 EFO-27 CTRP1 0.2604 33.3330
ML214 JHOC-5 CTRP1 0.2604 33.3330
ML214 JHOM-1 CTRP1 0.2604 33.3330
ML214 OAW42 CTRP1 0.2604 33.3330
ML214 OV7 CTRP1 0.2604 33.3330
ML214 OV-90 CTRP1 0.2604 33.3330
ML214 OVK18 CTRP1 0.2604 33.3330
ML214 RMG-I CTRP1 0.2604 33.3330
ML214 RMUG-S CTRP1 0.2604 33.3330
ML214 SNU-840 CTRP1 0.2604 33.3330
ML214 TYK-NU CTRP1 0.2604 33.3330
ML214 A-375 CTRP1 0.2604 33.3330
ML214 SK-MEL-1 CTRP1 0.2604 33.3330
ML214 SK-MEL-28 CTRP1 0.2604 33.3330
ML214 SK-MEL-5 CTRP1 0.2604 33.3330
ML214 HT-1080 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.