Drug : Alda-1

CTRP1 Name : Alda-1

Dataset : All
Synonyms :
Targets : ALDH2
Pathways : activator of aldehyde dehydrogenase 2

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
Alda-1 MCF-7 CTRP1 1.0417 133.3300
Alda-1 GAMG CTRP1 0.2603 33.3330
Alda-1 LN-229 CTRP1 1.0417 133.3300
Alda-1 SF295 CTRP1 0.2603 33.3330
Alda-1 HEC-108 CTRP1 0.2603 33.3330
Alda-1 HEC-151 CTRP1 1.0417 133.3300
Alda-1 HEC-251 CTRP1 0.2603 33.3330
Alda-1 HEC-265 CTRP1 0.2603 33.3330
Alda-1 HEC-59 CTRP1 0.2603 33.3330
Alda-1 HEC-6 CTRP1 0.2603 33.3330
Alda-1 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
Alda-1 JHUEM-2 CTRP1 1.0417 133.3300
Alda-1 KLE CTRP1 0.2603 33.3330
Alda-1 MFE-319 CTRP1 0.2603 33.3330
Alda-1 SNG-M CTRP1 0.2603 33.3330
Alda-1 AMO1 CTRP1 1.0417 133.3300
Alda-1 BL-70 CTRP1 0.2603 33.3330
Alda-1 EJM CTRP1 1.0417 133.3300
Alda-1 GDM-1 CTRP1 1.0417 133.3300
Alda-1 HT CTRP1 0.2603 33.3330
Alda-1 KMS-11 CTRP1 1.0417 133.3300
Alda-1 KU812 CTRP1 0.2603 33.3330
Alda-1 LP-1 CTRP1 1.0417 133.3300
Alda-1 MC116 CTRP1 0.2603 33.3330
Alda-1 MOLM-16 CTRP1 1.0417 133.3300
Alda-1 NOMO-1 CTRP1 1.0417 133.3300
Alda-1 NU-DUL-1 CTRP1 1.0417 133.3300
Alda-1 OCI-AML-3 CTRP1 1.0417 133.3300
Alda-1 OCI-LY10 CTRP1 1.0417 133.3300
Alda-1 P3HR-1 CTRP1 0.2603 33.3330
Alda-1 PL21 CTRP1 1.0417 133.3300
Alda-1 RPMI-8226 CTRP1 1.0417 133.3300
Alda-1 SKM-1 CTRP1 1.0417 133.3300
Alda-1 SU-DHL-4 CTRP1 1.0417 133.3300
Alda-1 SU-DHL-5 CTRP1 1.0417 133.3300
Alda-1 THP-1 CTRP1 1.0417 133.3300
Alda-1 U-937 CTRP1 1.0417 133.3300
Alda-1 WSU-DLCL2 CTRP1 1.0417 133.3300
Alda-1 RCC10RGB CTRP1 1.0417 133.3300
Alda-1 VMRC-RCW CTRP1 0.2603 33.3330
Alda-1 C2BBE1 CTRP1 0.2603 33.3330
Alda-1 CL-34 CTRP1 1.0417 133.3300
Alda-1 CL-40 CTRP1 1.0417 133.3300
Alda-1 COLO205 CTRP1 0.2603 33.3330
Alda-1 COLO320 CTRP1 1.0417 133.3300
Alda-1 COLO678 CTRP1 1.0417 133.3300
Alda-1 CW-2 CTRP1 1.0417 133.3300
Alda-1 DLD-1 CTRP1 0.2603 33.3330
Alda-1 GP2D CTRP1 0.2603 33.3330
Alda-1 HCT116 CTRP1 1.0417 133.3300
Alda-1 HCT8 CTRP1 1.0417 133.3300
Alda-1 HT115 CTRP1 1.0417 133.3300
Alda-1 HT-29 CTRP1 1.0417 133.3300
Alda-1 HT-55 CTRP1 1.0417 133.3300
Alda-1 KM12 CTRP1 1.0417 133.3300
Alda-1 LOVO CTRP1 1.0417 133.3300
Alda-1 LS123 CTRP1 1.0417 133.3300
Alda-1 LS180 CTRP1 1.0417 133.3300
Alda-1 LS411N CTRP1 0.2603 33.3330
Alda-1 LS513 CTRP1 0.2603 33.3330
Alda-1 MDST8 CTRP1 1.0417 133.3300
Alda-1 NCI-H508 CTRP1 1.0417 133.3300
Alda-1 RCM-1[HUMANESC] CTRP1 1.0417 133.3300
Alda-1 RKO CTRP1 1.0417 133.3300
Alda-1 SK-CO-1 CTRP1 0.2603 33.3330
Alda-1 SNU-1040 CTRP1 1.0417 133.3300
Alda-1 SNU-175 CTRP1 1.0417 133.3300
Alda-1 SNU-61 CTRP1 1.0417 133.3300
Alda-1 SNU-81 CTRP1 1.0417 133.3300
Alda-1 SNU-C2A CTRP1 0.2603 33.3330
Alda-1 SNU-C4 CTRP1 1.0417 133.3300
Alda-1 SNU-C5 CTRP1 1.0417 133.3300
Alda-1 SW403 CTRP1 0.2603 33.3330
Alda-1 SW48 CTRP1 0.2603 33.3330
Alda-1 SW480 CTRP1 1.0417 133.3300
Alda-1 SW620 CTRP1 1.0417 133.3300
Alda-1 SW948 CTRP1 1.0417 133.3300
Alda-1 HEP-G2 CTRP1 1.0417 133.3300
Alda-1 JHH-6 CTRP1 0.2603 33.3330
Alda-1 SNU-398 CTRP1 1.0417 133.3300
Alda-1 SNU-449 CTRP1 0.2603 33.3330
Alda-1 A-549 CTRP1 0.2603 33.3330
Alda-1 BEN CTRP1 0.2603 33.3330
Alda-1 CAL-12T CTRP1 1.0417 133.3300
Alda-1 CALU-3 CTRP1 0.2603 33.3330
Alda-1 CALU-6 CTRP1 0.2603 33.3330
Alda-1 CHAGO-K-1 CTRP1 0.2603 33.3330
Alda-1 COLO668 CTRP1 0.2603 33.3330
Alda-1 COLO699 CTRP1 1.0417 133.3300
Alda-1 COR-L23 CTRP1 1.0417 133.3300
Alda-1 COR-L279 CTRP1 0.2603 33.3330
Alda-1 COR-L51 CTRP1 1.0417 133.3300
Alda-1 COR-L88 CTRP1 0.2603 33.3330
Alda-1 DMS273 CTRP1 0.2603 33.3330
Alda-1 DV-90 CTRP1 0.2603 33.3330
Alda-1 EBC-1 CTRP1 0.2603 33.3330
Alda-1 EPLC-272H CTRP1 0.2603 33.3330
Alda-1 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
Alda-1 HCC1195 CTRP1 1.0417 133.3300
Alda-1 HCC1359 CTRP1 1.0417 133.3300
Alda-1 HCC15 CTRP1 1.0417 133.3300
Alda-1 HCC1833 CTRP1 1.0417 133.3300
Alda-1 HCC2108 CTRP1 1.0417 133.3300
Alda-1 HCC2935 CTRP1 1.0417 133.3300
Alda-1 HCC33 CTRP1 0.2603 33.3330
Alda-1 HCC4006 CTRP1 1.0417 133.3300
Alda-1 HCC44 CTRP1 0.2603 33.3330
Alda-1 HCC78 CTRP1 0.2603 33.3330
Alda-1 HCC827 CTRP1 1.0417 133.3300
Alda-1 KNS-62 CTRP1 0.2603 33.3330
Alda-1 LC-1-SQ-SF CTRP1 0.2603 33.3330
Alda-1 LCLC-103H CTRP1 0.2603 33.3330
Alda-1 LCLC-97TM1 CTRP1 0.2603 33.3330
Alda-1 LU-65 CTRP1 0.2603 33.3330
Alda-1 LU-99 CTRP1 0.2603 33.3330
Alda-1 LXF289 CTRP1 0.2603 33.3330
Alda-1 NCI-H1048 CTRP1 0.2603 33.3330
Alda-1 NCI-H1105 CTRP1 1.0417 133.3300
Alda-1 NCI-H1299 CTRP1 0.2603 33.3330
Alda-1 NCI-H1355 CTRP1 0.2603 33.3330
Alda-1 NCI-H1373 CTRP1 0.2603 33.3330
Alda-1 NCI-H1435 CTRP1 0.2603 33.3330
Alda-1 NCI-H1437 CTRP1 0.2603 33.3330
Alda-1 NCI-H1568 CTRP1 0.2603 33.3330
Alda-1 NCI-H1573 CTRP1 0.2603 33.3330
Alda-1 NCI-H1666 CTRP1 0.2603 33.3330
Alda-1 NCI-H1694 CTRP1 1.0417 133.3300
Alda-1 NCI-H1755 CTRP1 1.0417 133.3300
Alda-1 NCI-H1781 CTRP1 1.0417 133.3300
Alda-1 NCI-H1792 CTRP1 0.2603 33.3330
Alda-1 NCI-H1793 CTRP1 0.2603 33.3330
Alda-1 NCI-H1836 CTRP1 1.0417 133.3300
Alda-1 NCI-H1876 CTRP1 1.0417 133.3300
Alda-1 NCI-H1915 CTRP1 0.2603 33.3330
Alda-1 NCI-H1930 CTRP1 0.2603 33.3330
Alda-1 NCI-H1944 CTRP1 0.2603 33.3330
Alda-1 NCI-H1963 CTRP1 1.0417 133.3300
Alda-1 NCI-H1975 CTRP1 0.2603 33.3330
Alda-1 NCI-H2009 CTRP1 0.2603 33.3330
Alda-1 NCI-H2023 CTRP1 1.0417 133.3300
Alda-1 NCI-H2029 CTRP1 0.2603 33.3330
Alda-1 NCI-H2030 CTRP1 1.0417 133.3300
Alda-1 NCI-H2073 CTRP1 1.0417 133.3300
Alda-1 NCI-H2081 CTRP1 1.0417 133.3300
Alda-1 NCI-H2110 CTRP1 1.0417 133.3300
Alda-1 NCI-H2122 CTRP1 1.0417 133.3300
Alda-1 NCI-H2126 CTRP1 0.2603 33.3330
Alda-1 NCI-H2141 CTRP1 1.0417 133.3300
Alda-1 NCI-H2172 CTRP1 1.0417 133.3300
Alda-1 NCI-H2286 CTRP1 0.2603 33.3330
Alda-1 NCI-H23 CTRP1 0.2603 33.3330
Alda-1 NCI-H2342 CTRP1 1.0417 133.3300
Alda-1 NCI-H2405 CTRP1 0.2603 33.3330
Alda-1 NCI-H3255 CTRP1 1.0417 133.3300
Alda-1 NCI-H358 CTRP1 0.2603 33.3330
Alda-1 NCI-H441 CTRP1 1.0417 133.3300
Alda-1 NCI-H460 CTRP1 1.0417 133.3300
Alda-1 NCI-H522 CTRP1 0.2603 33.3330
Alda-1 NCI-H596 CTRP1 1.0417 133.3300
Alda-1 NCI-H650 CTRP1 0.2603 33.3330
Alda-1 NCI-H661 CTRP1 0.2603 33.3330
Alda-1 NCI-H727 CTRP1 0.2603 33.3330
Alda-1 NCI-H810 CTRP1 0.2603 33.3330
Alda-1 NCI-H82 CTRP1 0.2603 33.3330
Alda-1 NCI-H841 CTRP1 1.0417 133.3300
Alda-1 RERF-LC-KJ CTRP1 0.2603 33.3330
Alda-1 SCLC-21H CTRP1 1.0417 133.3300
Alda-1 SHP-77 CTRP1 0.2603 33.3330
Alda-1 SK-LU-1 CTRP1 1.0417 133.3300
Alda-1 SQ-1 CTRP1 1.0417 133.3300
Alda-1 T3M-10 CTRP1 1.0417 133.3300
Alda-1 VMRC-LCD CTRP1 0.2603 33.3330
Alda-1 KYSE-140 CTRP1 0.2603 33.3330
Alda-1 KYSE-410 CTRP1 0.2603 33.3330
Alda-1 KYSE-450 CTRP1 0.2603 33.3330
Alda-1 A2780 CTRP1 1.0417 133.3300
Alda-1 CAOV-3 CTRP1 1.0417 133.3300
Alda-1 COV318 CTRP1 0.2603 33.3330
Alda-1 COV362 CTRP1 1.0417 133.3300
Alda-1 COV434 CTRP1 1.0417 133.3300
Alda-1 COV644 CTRP1 1.0417 133.3300
Alda-1 EFO-21 CTRP1 0.2603 33.3330
Alda-1 EFO-27 CTRP1 1.0417 133.3300
Alda-1 HEYA8 CTRP1 0.2603 33.3330
Alda-1 IGROV-1 CTRP1 1.0417 133.3300
Alda-1 JHOC-5 CTRP1 1.0417 133.3300
Alda-1 JHOM-1 CTRP1 1.0417 133.3300
Alda-1 JHOS-4 CTRP1 0.2603 33.3330
Alda-1 OAW42 CTRP1 1.0417 133.3300
Alda-1 OV7 CTRP1 1.0417 133.3300
Alda-1 OV-90 CTRP1 1.0417 133.3300
Alda-1 OVCAR-4 CTRP1 1.0417 133.3300
Alda-1 OVCAR-8 CTRP1 1.0417 133.3300
Alda-1 OVK18 CTRP1 1.0417 133.3300
Alda-1 OVKATE CTRP1 1.0417 133.3300
Alda-1 OVMANA CTRP1 0.2603 33.3330
Alda-1 RKN CTRP1 1.0417 133.3300
Alda-1 RMG-I CTRP1 1.0417 133.3300
Alda-1 RMUG-S CTRP1 1.0417 133.3300
Alda-1 SK-OV-3 CTRP1 0.2603 33.3330
Alda-1 SNU-840 CTRP1 1.0417 133.3300
Alda-1 TYK-NU CTRP1 1.0417 133.3300
Alda-1 CAPAN-2 CTRP1 0.2603 33.3330
Alda-1 CFPAC-1 CTRP1 0.2603 33.3330
Alda-1 HPAC CTRP1 0.2603 33.3330
Alda-1 HUP-T4 CTRP1 0.2603 33.3330
Alda-1 KP-3 CTRP1 0.2603 33.3330
Alda-1 PANC03.27 CTRP1 0.2603 33.3330
Alda-1 PANC10.05 CTRP1 0.2603 33.3330
Alda-1 PATU8902 CTRP1 0.2603 33.3330
Alda-1 QGP-1 CTRP1 0.2603 33.3330
Alda-1 SUIT-2 CTRP1 0.2603 33.3330
Alda-1 MSTO-211H CTRP1 0.2603 33.3330
Alda-1 NCI-H2052 CTRP1 0.2603 33.3330
Alda-1 NCI-H28 CTRP1 0.2603 33.3330
Alda-1 MIAPACA-3 CTRP1 0.2603 33.3330
Alda-1 A-375 CTRP1 1.0417 133.3300
Alda-1 COLO741 CTRP1 0.2603 33.3330
Alda-1 G-361 CTRP1 0.2603 33.3330
Alda-1 HS852.T CTRP1 0.2603 33.3330
Alda-1 HS936.T CTRP1 0.2603 33.3330
Alda-1 HS944.T CTRP1 0.2603 33.3330
Alda-1 SK-MEL-1 CTRP1 1.0417 133.3300
Alda-1 SK-MEL-28 CTRP1 1.0417 133.3300
Alda-1 SK-MEL-5 CTRP1 1.0417 133.3300
Alda-1 G-401 CTRP1 0.2603 33.3330
Alda-1 HT-1080 CTRP1 1.0417 133.3300
Alda-1 AGS CTRP1 1.0417 133.3300
Alda-1 FU97 CTRP1 0.2603 33.3330
Alda-1 KE-97 CTRP1 0.2603 33.3330
Alda-1 MKN7 CTRP1 0.2603 33.3330
Alda-1 MKN74 CTRP1 0.2603 33.3330
Alda-1 NUGC-4 CTRP1 0.2603 33.3330
Alda-1 SH-10-TC CTRP1 0.2603 33.3330
Alda-1 HSC-2 CTRP1 0.2603 33.3330
Alda-1 SCC-9 CTRP1 1.0417 133.3300
Alda-1 5637 CTRP1 0.2603 33.3330
Alda-1 HT-1376 CTRP1 0.2603 33.3330
Alda-1 KMBC-2 CTRP1 0.2603 33.3330
Alda-1 RT-4 CTRP1 0.2603 33.3330
Alda-1 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.