Drug : Brd2296

CTRP1 Name : BRD2296

Dataset : All
Synonyms :
Targets :
Pathways : product of diversity-oriented synthesis

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

:


Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
BRD2296 MCF-7 CTRP1 0.2604 33.3330
BRD2296 LN-229 CTRP1 0.2604 33.3330
BRD2296 JHUEM-2 CTRP1 0.2604 33.3330
BRD2296 EJM CTRP1 0.2604 33.3330
BRD2296 GDM-1 CTRP1 0.2604 33.3330
BRD2296 MOLM-16 CTRP1 0.2604 33.3330
BRD2296 NOMO-1 CTRP1 0.2604 33.3330
BRD2296 NU-DUL-1 CTRP1 0.2604 33.3330
BRD2296 OCI-AML-3 CTRP1 0.2604 33.3330
BRD2296 PL21 CTRP1 0.2604 33.3330
BRD2296 RPMI-8226 CTRP1 0.2604 33.3330
BRD2296 SKM-1 CTRP1 0.2604 33.3330
BRD2296 SU-DHL-4 CTRP1 0.2604 33.3330
BRD2296 SU-DHL-5 CTRP1 0.2604 33.3330
BRD2296 THP-1 CTRP1 0.2604 33.3330
BRD2296 U-937 CTRP1 0.2604 33.3330
BRD2296 WSU-DLCL2 CTRP1 0.2604 33.3330
BRD2296 CL-34 CTRP1 0.2604 33.3330
BRD2296 CL-40 CTRP1 0.2604 33.3330
BRD2296 COLO320 CTRP1 0.2604 33.3330
BRD2296 COLO678 CTRP1 0.2604 33.3330
BRD2296 CW-2 CTRP1 0.2604 33.3330
BRD2296 HCT116 CTRP1 0.2604 33.3330
BRD2296 HCT8 CTRP1 0.2604 33.3330
BRD2296 HT115 CTRP1 0.2604 33.3330
BRD2296 HT-29 CTRP1 0.2604 33.3330
BRD2296 HT-55 CTRP1 0.2604 33.3330
BRD2296 KM12 CTRP1 0.2604 33.3330
BRD2296 LOVO CTRP1 0.2604 33.3330
BRD2296 LS123 CTRP1 0.2604 33.3330
BRD2296 MDST8 CTRP1 0.2604 33.3330
BRD2296 NCI-H508 CTRP1 0.2604 33.3330
BRD2296 RCM-1[HUMANESC] CTRP1 0.2604 33.3330
BRD2296 RKO CTRP1 0.2604 33.3330
BRD2296 SNU-1040 CTRP1 0.2604 33.3330
BRD2296 SNU-175 CTRP1 0.2604 33.3330
BRD2296 SNU-61 CTRP1 0.2604 33.3330
BRD2296 SNU-81 CTRP1 0.2604 33.3330
BRD2296 SNU-C4 CTRP1 0.2604 33.3330
BRD2296 SNU-C5 CTRP1 0.2604 33.3330
BRD2296 SW480 CTRP1 0.2604 33.3330
BRD2296 SW620 CTRP1 0.2604 33.3330
BRD2296 SW948 CTRP1 0.2604 33.3330
BRD2296 HEP-G2 CTRP1 0.2604 33.3330
BRD2296 CAL-12T CTRP1 0.2604 33.3330
BRD2296 COLO699 CTRP1 0.2604 33.3330
BRD2296 COR-L23 CTRP1 0.2604 33.3330
BRD2296 HCC1195 CTRP1 0.2604 33.3330
BRD2296 HCC1359 CTRP1 0.2604 33.3330
BRD2296 HCC15 CTRP1 0.2604 33.3330
BRD2296 HCC1833 CTRP1 0.2604 33.3330
BRD2296 HCC2108 CTRP1 0.2604 33.3330
BRD2296 HCC2935 CTRP1 0.2604 33.3330
BRD2296 HCC4006 CTRP1 0.2604 33.3330
BRD2296 HCC827 CTRP1 0.2604 33.3330
BRD2296 NCI-H1105 CTRP1 0.2604 33.3330
BRD2296 NCI-H1694 CTRP1 0.2604 33.3330
BRD2296 NCI-H1755 CTRP1 0.2604 33.3330
BRD2296 NCI-H1781 CTRP1 0.2604 33.3330
BRD2296 NCI-H1836 CTRP1 0.2604 33.3330
BRD2296 NCI-H1876 CTRP1 0.2604 33.3330
BRD2296 NCI-H2023 CTRP1 0.2604 33.3330
BRD2296 NCI-H2030 CTRP1 0.2604 33.3330
BRD2296 NCI-H2073 CTRP1 0.2604 33.3330
BRD2296 NCI-H2081 CTRP1 0.2604 33.3330
BRD2296 NCI-H2110 CTRP1 0.2604 33.3330
BRD2296 NCI-H2122 CTRP1 0.2604 33.3330
BRD2296 NCI-H2172 CTRP1 0.2604 33.3330
BRD2296 NCI-H2342 CTRP1 0.2604 33.3330
BRD2296 NCI-H3255 CTRP1 0.2604 33.3330
BRD2296 NCI-H441 CTRP1 0.2604 33.3330
BRD2296 NCI-H460 CTRP1 0.2604 33.3330
BRD2296 NCI-H596 CTRP1 0.2604 33.3330
BRD2296 NCI-H841 CTRP1 0.2604 33.3330
BRD2296 SK-LU-1 CTRP1 0.2604 33.3330
BRD2296 SQ-1 CTRP1 0.2604 33.3330
BRD2296 T3M-10 CTRP1 0.2604 33.3330
BRD2296 CAOV-3 CTRP1 0.2604 33.3330
BRD2296 COV362 CTRP1 0.2604 33.3330
BRD2296 COV434 CTRP1 0.2604 33.3330
BRD2296 COV644 CTRP1 0.2604 33.3330
BRD2296 EFO-27 CTRP1 0.2604 33.3330
BRD2296 JHOC-5 CTRP1 0.2604 33.3330
BRD2296 JHOM-1 CTRP1 0.2604 33.3330
BRD2296 OAW42 CTRP1 0.2604 33.3330
BRD2296 OV7 CTRP1 0.2604 33.3330
BRD2296 OV-90 CTRP1 0.2604 33.3330
BRD2296 OVK18 CTRP1 0.2604 33.3330
BRD2296 RMG-I CTRP1 0.2604 33.3330
BRD2296 RMUG-S CTRP1 0.2604 33.3330
BRD2296 SNU-840 CTRP1 0.2604 33.3330
BRD2296 TYK-NU CTRP1 0.2604 33.3330
BRD2296 A-375 CTRP1 0.2604 33.3330
BRD2296 SK-MEL-1 CTRP1 0.2604 33.3330
BRD2296 SK-MEL-28 CTRP1 0.2604 33.3330
BRD2296 SK-MEL-5 CTRP1 0.2604 33.3330
BRD2296 HT-1080 CTRP1 0.2604 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.