Drug : Dg-041

CTRP1 Name : DG-041

Dataset : All
Synonyms :
Targets : PTGER3
Pathways : inhibitor of prostaglandin E receptor 3 (subtype EP3)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
DG-041 MCF-7 CTRP1 1.0417 133.3300
DG-041 GAMG CTRP1 0.2603 33.3330
DG-041 LN-229 CTRP1 1.0417 133.3300
DG-041 SF295 CTRP1 0.2603 33.3330
DG-041 HEC-108 CTRP1 0.2603 33.3330
DG-041 HEC-151 CTRP1 0.5208 133.3300
DG-041 HEC-251 CTRP1 0.2603 33.3330
DG-041 HEC-265 CTRP1 0.2603 33.3330
DG-041 HEC-59 CTRP1 0.2603 33.3330
DG-041 HEC-6 CTRP1 0.2603 33.3330
DG-041 ISHIKAWA(HERAKLIO)02ER- CTRP1 0.2603 33.3330
DG-041 JHUEM-2 CTRP1 1.0417 133.3300
DG-041 KLE CTRP1 0.2603 33.3330
DG-041 MFE-319 CTRP1 0.2603 33.3330
DG-041 SNG-M CTRP1 0.2603 33.3330
DG-041 AMO1 CTRP1 0.5208 133.3300
DG-041 BL-70 CTRP1 0.2603 33.3330
DG-041 EJM CTRP1 1.0417 133.3300
DG-041 GDM-1 CTRP1 1.0417 133.3300
DG-041 HT CTRP1 0.2603 33.3330
DG-041 KMS-11 CTRP1 0.5208 133.3300
DG-041 KU812 CTRP1 0.2603 33.3330
DG-041 LP-1 CTRP1 0.5208 133.3300
DG-041 MC116 CTRP1 0.2603 33.3330
DG-041 MOLM-16 CTRP1 1.0417 133.3300
DG-041 NOMO-1 CTRP1 1.0417 133.3300
DG-041 NU-DUL-1 CTRP1 1.0417 133.3300
DG-041 OCI-AML-3 CTRP1 1.0417 133.3300
DG-041 OCI-LY10 CTRP1 0.5208 133.3300
DG-041 P3HR-1 CTRP1 0.2603 33.3330
DG-041 PL21 CTRP1 1.0417 133.3300
DG-041 RPMI-8226 CTRP1 1.0417 133.3300
DG-041 SKM-1 CTRP1 1.0417 133.3300
DG-041 SU-DHL-4 CTRP1 1.0417 133.3300
DG-041 SU-DHL-5 CTRP1 1.0417 133.3300
DG-041 THP-1 CTRP1 1.0417 133.3300
DG-041 U-937 CTRP1 1.0417 133.3300
DG-041 WSU-DLCL2 CTRP1 1.0417 133.3300
DG-041 VMRC-RCW CTRP1 0.2603 33.3330
DG-041 C2BBE1 CTRP1 0.2603 33.3330
DG-041 CL-34 CTRP1 1.0417 133.3300
DG-041 CL-40 CTRP1 1.0417 133.3300
DG-041 COLO205 CTRP1 0.2603 33.3330
DG-041 COLO320 CTRP1 1.0417 133.3300
DG-041 COLO678 CTRP1 1.0417 133.3300
DG-041 CW-2 CTRP1 1.0417 133.3300
DG-041 DLD-1 CTRP1 0.2603 33.3330
DG-041 GP2D CTRP1 0.2603 33.3330
DG-041 HCT116 CTRP1 1.0417 133.3300
DG-041 HCT8 CTRP1 1.0417 133.3300
DG-041 HT115 CTRP1 1.0417 133.3300
DG-041 HT-29 CTRP1 1.0417 133.3300
DG-041 HT-55 CTRP1 1.0417 133.3300
DG-041 KM12 CTRP1 1.0417 133.3300
DG-041 LOVO CTRP1 1.0417 133.3300
DG-041 LS123 CTRP1 1.0417 133.3300
DG-041 LS180 CTRP1 0.5208 133.3300
DG-041 LS411N CTRP1 0.2603 33.3330
DG-041 LS513 CTRP1 0.2603 33.3330
DG-041 MDST8 CTRP1 1.0417 133.3300
DG-041 NCI-H508 CTRP1 1.0417 133.3300
DG-041 RCM-1[HUMANESC] CTRP1 1.0417 133.3300
DG-041 RKO CTRP1 1.0417 133.3300
DG-041 SK-CO-1 CTRP1 0.2603 33.3330
DG-041 SNU-1040 CTRP1 1.0417 133.3300
DG-041 SNU-175 CTRP1 1.0417 133.3300
DG-041 SNU-61 CTRP1 1.0417 133.3300
DG-041 SNU-81 CTRP1 1.0417 133.3300
DG-041 SNU-C2A CTRP1 0.2603 33.3330
DG-041 SNU-C4 CTRP1 1.0417 133.3300
DG-041 SNU-C5 CTRP1 1.0417 133.3300
DG-041 SW403 CTRP1 0.2603 33.3330
DG-041 SW48 CTRP1 0.2603 33.3330
DG-041 SW480 CTRP1 1.0417 133.3300
DG-041 SW620 CTRP1 1.0417 133.3300
DG-041 SW948 CTRP1 1.0417 133.3300
DG-041 HEP-G2 CTRP1 1.0417 133.3300
DG-041 JHH-6 CTRP1 0.2603 33.3330
DG-041 SNU-398 CTRP1 0.5208 133.3300
DG-041 SNU-449 CTRP1 0.2603 33.3330
DG-041 A-549 CTRP1 0.2603 33.3330
DG-041 BEN CTRP1 0.2603 33.3330
DG-041 CAL-12T CTRP1 1.0417 133.3300
DG-041 CALU-3 CTRP1 0.2603 33.3330
DG-041 CALU-6 CTRP1 0.2603 33.3330
DG-041 CHAGO-K-1 CTRP1 0.2603 33.3330
DG-041 COLO668 CTRP1 0.2603 33.3330
DG-041 COLO699 CTRP1 1.0417 133.3300
DG-041 COR-L23 CTRP1 1.0417 133.3300
DG-041 COR-L279 CTRP1 0.2603 33.3330
DG-041 COR-L51 CTRP1 0.5208 133.3300
DG-041 COR-L88 CTRP1 0.2603 33.3330
DG-041 DMS273 CTRP1 0.2603 33.3330
DG-041 DV-90 CTRP1 0.2603 33.3330
DG-041 EBC-1 CTRP1 0.2603 33.3330
DG-041 EPLC-272H CTRP1 0.2603 33.3330
DG-041 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP1 0.2603 33.3330
DG-041 HCC1195 CTRP1 1.0417 133.3300
DG-041 HCC1359 CTRP1 1.0417 133.3300
DG-041 HCC15 CTRP1 1.0417 133.3300
DG-041 HCC1833 CTRP1 1.0417 133.3300
DG-041 HCC2108 CTRP1 1.0417 133.3300
DG-041 HCC2935 CTRP1 1.0417 133.3300
DG-041 HCC33 CTRP1 0.2603 33.3330
DG-041 HCC4006 CTRP1 1.0417 133.3300
DG-041 HCC44 CTRP1 0.2603 33.3330
DG-041 HCC78 CTRP1 0.2603 33.3330
DG-041 HCC827 CTRP1 1.0417 133.3300
DG-041 KNS-62 CTRP1 0.2603 33.3330
DG-041 LC-1-SQ-SF CTRP1 0.2603 33.3330
DG-041 LCLC-103H CTRP1 0.2603 33.3330
DG-041 LCLC-97TM1 CTRP1 0.2603 33.3330
DG-041 LU-65 CTRP1 0.2603 33.3330
DG-041 LU-99 CTRP1 0.2603 33.3330
DG-041 LXF289 CTRP1 0.2603 33.3330
DG-041 NCI-H1048 CTRP1 0.2603 33.3330
DG-041 NCI-H1105 CTRP1 1.0417 133.3300
DG-041 NCI-H1299 CTRP1 0.2603 33.3330
DG-041 NCI-H1355 CTRP1 0.2603 33.3330
DG-041 NCI-H1373 CTRP1 0.2603 33.3330
DG-041 NCI-H1435 CTRP1 0.2603 33.3330
DG-041 NCI-H1437 CTRP1 0.2603 33.3330
DG-041 NCI-H1568 CTRP1 0.2603 33.3330
DG-041 NCI-H1573 CTRP1 0.2603 33.3330
DG-041 NCI-H1666 CTRP1 0.2603 33.3330
DG-041 NCI-H1694 CTRP1 1.0417 133.3300
DG-041 NCI-H1755 CTRP1 1.0417 133.3300
DG-041 NCI-H1781 CTRP1 1.0417 133.3300
DG-041 NCI-H1792 CTRP1 0.2603 33.3330
DG-041 NCI-H1793 CTRP1 0.2603 33.3330
DG-041 NCI-H1836 CTRP1 1.0417 133.3300
DG-041 NCI-H1876 CTRP1 1.0417 133.3300
DG-041 NCI-H1915 CTRP1 0.2603 33.3330
DG-041 NCI-H1930 CTRP1 0.2603 33.3330
DG-041 NCI-H1944 CTRP1 0.2603 33.3330
DG-041 NCI-H1963 CTRP1 0.5208 133.3300
DG-041 NCI-H1975 CTRP1 0.2603 33.3330
DG-041 NCI-H2009 CTRP1 0.2603 33.3330
DG-041 NCI-H2023 CTRP1 1.0417 133.3300
DG-041 NCI-H2029 CTRP1 0.2603 33.3330
DG-041 NCI-H2030 CTRP1 1.0417 133.3300
DG-041 NCI-H2073 CTRP1 1.0417 133.3300
DG-041 NCI-H2081 CTRP1 1.0417 133.3300
DG-041 NCI-H2110 CTRP1 1.0417 133.3300
DG-041 NCI-H2122 CTRP1 1.0417 133.3300
DG-041 NCI-H2126 CTRP1 0.2603 33.3330
DG-041 NCI-H2141 CTRP1 0.5208 133.3300
DG-041 NCI-H2172 CTRP1 1.0417 133.3300
DG-041 NCI-H2286 CTRP1 0.2603 33.3330
DG-041 NCI-H23 CTRP1 0.2603 33.3330
DG-041 NCI-H2342 CTRP1 1.0417 133.3300
DG-041 NCI-H2405 CTRP1 0.2603 33.3330
DG-041 NCI-H3255 CTRP1 1.0417 133.3300
DG-041 NCI-H358 CTRP1 0.2603 33.3330
DG-041 NCI-H441 CTRP1 1.0417 133.3300
DG-041 NCI-H460 CTRP1 1.0417 133.3300
DG-041 NCI-H522 CTRP1 0.2603 33.3330
DG-041 NCI-H596 CTRP1 1.0417 133.3300
DG-041 NCI-H650 CTRP1 0.2603 33.3330
DG-041 NCI-H661 CTRP1 0.2603 33.3330
DG-041 NCI-H727 CTRP1 0.2603 33.3330
DG-041 NCI-H810 CTRP1 0.2603 33.3330
DG-041 NCI-H82 CTRP1 0.2603 33.3330
DG-041 NCI-H841 CTRP1 1.0417 133.3300
DG-041 RERF-LC-KJ CTRP1 0.2603 33.3330
DG-041 SCLC-21H CTRP1 0.5208 133.3300
DG-041 SHP-77 CTRP1 0.2603 33.3330
DG-041 SK-LU-1 CTRP1 1.0417 133.3300
DG-041 SQ-1 CTRP1 1.0417 133.3300
DG-041 T3M-10 CTRP1 1.0417 133.3300
DG-041 VMRC-LCD CTRP1 0.2603 33.3330
DG-041 KYSE-140 CTRP1 0.2603 33.3330
DG-041 KYSE-410 CTRP1 0.2603 33.3330
DG-041 KYSE-450 CTRP1 0.2603 33.3330
DG-041 A2780 CTRP1 0.5208 133.3300
DG-041 CAOV-3 CTRP1 1.0417 133.3300
DG-041 COV318 CTRP1 0.2603 33.3330
DG-041 COV362 CTRP1 1.0417 133.3300
DG-041 COV434 CTRP1 1.0417 133.3300
DG-041 COV644 CTRP1 1.0417 133.3300
DG-041 EFO-21 CTRP1 0.2603 33.3330
DG-041 EFO-27 CTRP1 1.0417 133.3300
DG-041 HEYA8 CTRP1 0.2603 33.3330
DG-041 IGROV-1 CTRP1 0.5208 133.3300
DG-041 JHOC-5 CTRP1 1.0417 133.3300
DG-041 JHOM-1 CTRP1 1.0417 133.3300
DG-041 JHOS-4 CTRP1 0.2603 33.3330
DG-041 OAW42 CTRP1 1.0417 133.3300
DG-041 OV7 CTRP1 1.0417 133.3300
DG-041 OV-90 CTRP1 1.0417 133.3300
DG-041 OVCAR-4 CTRP1 0.5208 133.3300
DG-041 OVCAR-8 CTRP1 0.5208 133.3300
DG-041 OVK18 CTRP1 1.0417 133.3300
DG-041 OVKATE CTRP1 0.5208 133.3300
DG-041 OVMANA CTRP1 0.2603 33.3330
DG-041 RKN CTRP1 0.5208 133.3300
DG-041 RMG-I CTRP1 1.0417 133.3300
DG-041 RMUG-S CTRP1 1.0417 133.3300
DG-041 SK-OV-3 CTRP1 0.2603 33.3330
DG-041 SNU-840 CTRP1 1.0417 133.3300
DG-041 TYK-NU CTRP1 1.0417 133.3300
DG-041 CAPAN-2 CTRP1 0.2603 33.3330
DG-041 CFPAC-1 CTRP1 0.2603 33.3330
DG-041 HPAC CTRP1 0.2603 33.3330
DG-041 HUP-T4 CTRP1 0.2603 33.3330
DG-041 KP-3 CTRP1 0.2603 33.3330
DG-041 PANC03.27 CTRP1 0.2603 33.3330
DG-041 PANC10.05 CTRP1 0.2603 33.3330
DG-041 PATU8902 CTRP1 0.2603 33.3330
DG-041 QGP-1 CTRP1 0.2603 33.3330
DG-041 SUIT-2 CTRP1 0.2603 33.3330
DG-041 MSTO-211H CTRP1 0.2603 33.3330
DG-041 NCI-H2052 CTRP1 0.2603 33.3330
DG-041 NCI-H28 CTRP1 0.2603 33.3330
DG-041 MIAPACA-3 CTRP1 0.2603 33.3330
DG-041 A-375 CTRP1 1.0417 133.3300
DG-041 COLO741 CTRP1 0.2603 33.3330
DG-041 G-361 CTRP1 0.2603 33.3330
DG-041 HS852.T CTRP1 0.2603 33.3330
DG-041 HS936.T CTRP1 0.2603 33.3330
DG-041 HS944.T CTRP1 0.2603 33.3330
DG-041 SK-MEL-1 CTRP1 1.0417 133.3300
DG-041 SK-MEL-28 CTRP1 1.0417 133.3300
DG-041 SK-MEL-5 CTRP1 1.0417 133.3300
DG-041 G-401 CTRP1 0.2603 33.3330
DG-041 HT-1080 CTRP1 1.0417 133.3300
DG-041 AGS CTRP1 0.5208 133.3300
DG-041 FU97 CTRP1 0.2603 33.3330
DG-041 KE-97 CTRP1 0.2603 33.3330
DG-041 MKN7 CTRP1 0.2603 33.3330
DG-041 MKN74 CTRP1 0.2603 33.3330
DG-041 NUGC-4 CTRP1 0.2603 33.3330
DG-041 SH-10-TC CTRP1 0.2603 33.3330
DG-041 HSC-2 CTRP1 0.2603 33.3330
DG-041 SCC-9 CTRP1 0.5208 133.3300
DG-041 5637 CTRP1 0.2603 33.3330
DG-041 HT-1376 CTRP1 0.2603 33.3330
DG-041 KMBC-2 CTRP1 0.2603 33.3330
DG-041 RT-4 CTRP1 0.2603 33.3330
DG-041 UM-UC-3 CTRP1 0.2603 33.3330

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.