Cell Line : NCI-H2073

Cellosaurus Index : CVCL_1521
Cellosaurus ID : NCI-H2073

CTRP1 Name , CTRP2 Name : NCIH2073
CCLE Name : NCIH2073_LUNG

Cancer Type : lung
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
NCI-H2073 (-)-gallocatechin-3-monogallate CTRP1 2.3125 296.0000
NCI-H2073 10-DEBC CTRP1 0.6250 80.0000
NCI-H2073 16-beta-bromoandrosterone CTRP1 0.2891 37.0000
NCI-H2073 16,16-dimethylprostaglandin-E2 CTRP1 0.2604 33.3330
NCI-H2073 1S,3R-RSL-3 CTRP1 0.0312 4.0000
NCI-H2073 2-bromopyruvate CTRP1 4.1667 533.3300
NCI-H2073 2-fluoropalmitic acid CTRP1 1.1562 148.0000
NCI-H2073 2,4-dideoxy-DC-45-A2 CTRP1 0.0163 2.0833
NCI-H2073 3-chloro-L-alanine CTRP1 0.0163 2.0833
NCI-H2073 4-IPP CTRP1 1.0417 133.3300
NCI-H2073 4-methylfasudil CTRP1 1.0417 133.3300
NCI-H2073 6-diazo-5-oxo-L-norleucine CTRP1 1.0417 133.3300
NCI-H2073 7-nitroindazole CTRP1 2.0833 266.6700
NCI-H2073 AA-COCF3 CTRP1 2.0833 266.6700
NCI-H2073 ABT-751 CTRP1 0.2604 33.3330
NCI-H2073 ABT737 CTRP1 0.2891 37.0000
NCI-H2073 AC55649 CTRP1 0.2604 33.3330
NCI-H2073 AGK-2 CTRP1 0.2604 33.3330
NCI-H2073 Alda-1 CTRP1 1.0417 133.3300
NCI-H2073 AM-580 CTRP1 4.1667 533.3300
NCI-H2073 ASN 05257430 CTRP1 0.2891 37.0000
NCI-H2073 austocystin D CTRP1 0.2891 37.0000
NCI-H2073 avrainvillamide CTRP1 0.2604 33.3330
NCI-H2073 AZD-7545 CTRP1 0.5781 74.0000
NCI-H2073 batimastat CTRP1 1.1562 148.0000
NCI-H2073 Bax channel blocker CTRP1 0.2604 33.3330
NCI-H2073 BEC CTRP1 2.0833 266.6700
NCI-H2073 BI-2536 CTRP1 0.2604 33.3330
NCI-H2073 BIBR-1532 CTRP1 2.0833 266.6700
NCI-H2073 BIX-01294 CTRP1 0.2604 33.3330
NCI-H2073 blebbistatin CTRP1 1.0417 133.3300
NCI-H2073 BML-259 CTRP1 2.0833 266.6700
NCI-H2073 BMS-191011 CTRP1 0.2604 33.3330
NCI-H2073 BMS-299897 CTRP1 0.2604 33.3330
NCI-H2073 BMS-536924 CTRP1 0.2891 37.0000
NCI-H2073 BMS-641988 CTRP1 0.2891 37.0000
NCI-H2073 BMS-754807 CTRP1 0.2604 33.3330
NCI-H2073 Bortezomib CTRP1 0.0010 0.1300
NCI-H2073 BRD0713 CTRP1 0.6250 80.0000
NCI-H2073 BRD1429 CTRP1 0.2604 33.3330
NCI-H2073 BRD1566 CTRP1 0.2683 34.3400
NCI-H2073 BRD1812 CTRP1 0.2604 33.3330
NCI-H2073 BRD2296 CTRP1 0.2604 33.3330
NCI-H2073 BRD2572 CTRP1 0.6250 80.0000
NCI-H2073 BRD2762 CTRP1 0.6250 80.0000
NCI-H2073 BRD4046 CTRP1 0.6250 80.0000
NCI-H2073 BRD4132 CTRP1 1.2500 160.0000
NCI-H2073 BRD4354 CTRP1 0.2604 33.3330
NCI-H2073 BRD4372 CTRP1 0.6250 80.0000
NCI-H2073 BRD4479 CTRP1 0.1823 23.3330
NCI-H2073 BRD4770 CTRP1 0.2604 33.3330
NCI-H2073 BRD55319 CTRP1 0.2891 37.0000
NCI-H2073 BRD5802 CTRP1 0.6250 80.0000
NCI-H2073 BRD6150 CTRP1 0.6250 80.0000
NCI-H2073 BRD6340 CTRP1 0.3125 40.0000
NCI-H2073 BRD63610 CTRP1 0.0081 1.0417
NCI-H2073 BRD6368 CTRP1 0.2604 33.3330
NCI-H2073 BRD6825 CTRP1 0.6250 80.0000
NCI-H2073 BRD7137 CTRP1 0.2604 33.3330
NCI-H2073 BRD8097 CTRP1 0.6250 80.0000
NCI-H2073 BRD8418 CTRP1 0.6250 80.0000
NCI-H2073 BRD8958 CTRP1 0.5208 66.6670
NCI-H2073 BRD9571 CTRP1 0.6250 80.0000
NCI-H2073 BRD9647 CTRP1 0.2344 30.0000
NCI-H2073 BRD9658 CTRP1 0.6250 80.0000
NCI-H2073 BRD9876 CTRP1 1.0417 133.3300
NCI-H2073 brefeldin A CTRP1 0.0023 0.2890
NCI-H2073 BX795 CTRP1 0.2604 33.3330
NCI-H2073 capsaicin CTRP1 4.1667 533.3300
NCI-H2073 carbamazepine CTRP1 2.5000 320.0000
NCI-H2073 CAY10594 CTRP1 0.5208 66.6670
NCI-H2073 CCT036477 CTRP1 0.2604 33.3330
NCI-H2073 CD-1530 CTRP1 1.0417 133.3300
NCI-H2073 CD-437 CTRP1 0.2891 37.0000
NCI-H2073 cerulenin CTRP1 1.1562 148.0000
NCI-H2073 chaetocin CTRP1 0.0020 0.2600
NCI-H2073 CHEMBL1222381 CTRP1 2.0833 266.6700
NCI-H2073 CHEMBL374350 CTRP1 0.2604 33.3330
NCI-H2073 CHEMBL399379 CTRP1 2.0833 266.6700
NCI-H2073 CHIR-99021 CTRP1 0.6250 80.0000
NCI-H2073 CHM-1 CTRP1 0.1250 16.0000
NCI-H2073 CI-976 CTRP1 2.0833 266.6700
NCI-H2073 ciclosporin CTRP1 0.2604 33.3330
NCI-H2073 CID 2853753 CTRP1 0.2604 33.3330
NCI-H2073 CIL41 CTRP1 1.2500 160.0000
NCI-H2073 CIL55 CTRP1 0.0781 10.0000
NCI-H2073 CIL55A CTRP1 0.6250 80.0000
NCI-H2073 CIL56 CTRP1 0.0195 2.5000
NCI-H2073 CIL70 CTRP1 0.3125 40.0000
NCI-H2073 Compound 10b CTRP1 1.1562 148.0000
NCI-H2073 Compound 110 CTRP1 0.5781 74.0000
NCI-H2073 Compound 11e CTRP1 0.0130 1.6667
NCI-H2073 Compound 12 CTRP1 0.2891 37.0000
NCI-H2073 Compound 1541A CTRP1 0.2891 37.0000
NCI-H2073 Compound 23 citrate CTRP1 0.2604 33.3330
NCI-H2073 Compound 4 CTRP1 0.2604 33.3330
NCI-H2073 Compound 44 CTRP1 1.0417 133.3300
NCI-H2073 Compound 7d-cis CTRP1 0.2604 33.3330
NCI-H2073 CR-1-31B CTRP1 0.2604 33.3330
NCI-H2073 curcumin CTRP1 1.2500 160.0000
NCI-H2073 cyanoquinoline 11 CTRP1 1.0417 133.3300
NCI-H2073 CYT-997 CTRP1 0.0260 3.3333
NCI-H2073 cytochalasin B CTRP1 0.2604 33.3330
NCI-H2073 cytosporone B CTRP1 0.2604 33.3330
NCI-H2073 Dactolisib CTRP1 0.0163 2.0833
NCI-H2073 dalcetrapib CTRP1 2.0687 264.8000
NCI-H2073 Daporinad CTRP1 0.0020 0.2600
NCI-H2073 darinaparsin CTRP1 0.2604 33.3330
NCI-H2073 DC-45-A2 CTRP1 0.2891 37.0000
NCI-H2073 dexamethasone CTRP1 0.2604 33.3330
NCI-H2073 DG-041 CTRP1 1.0417 133.3300
NCI-H2073 DL-TBOA CTRP1 4.1667 533.3300
NCI-H2073 ELCPK CTRP1 0.0031 0.4000
NCI-H2073 endo-IWR-1 CTRP1 0.2604 33.3330
NCI-H2073 erastin CTRP1 0.1250 16.0000
NCI-H2073 erastin-A8 CTRP1 0.1250 16.0000
NCI-H2073 etomoxir CTRP1 2.3125 296.0000
NCI-H2073 Etoposide CTRP1 0.2212 28.3180
NCI-H2073 fatostatin CTRP1 0.2604 33.3330
NCI-H2073 Fedratinib CTRP1 0.2891 37.0000
NCI-H2073 FGIN-1-27 CTRP1 0.2604 33.3330
NCI-H2073 fluoropyruvate CTRP1 1.1562 148.0000
NCI-H2073 Flutamide CTRP1 0.7542 96.5330
NCI-H2073 FQI-1 CTRP1 0.2604 33.3330
NCI-H2073 FQI-2 CTRP1 0.2604 33.3330
NCI-H2073 fumagillol CTRP1 4.1667 533.3300
NCI-H2073 fumonisin B1 CTRP1 3.9373 504.0000
NCI-H2073 GANT-58 CTRP1 0.2604 33.3330
NCI-H2073 Gemcitabine CTRP1 0.0020 0.2600
NCI-H2073 glibenclamide CTRP1 0.2604 33.3330
NCI-H2073 Gly-Gly-PALO CTRP1 2.0833 266.6700
NCI-H2073 GMX-1778 CTRP1 0.0020 0.2600
NCI-H2073 gossypol CTRP1 0.2891 37.0000
NCI-H2073 GSK-2334470 CTRP1 0.0026 0.3333
NCI-H2073 GW-405833 CTRP1 1.0417 133.3300
NCI-H2073 GW843682X CTRP1 0.2604 33.3330
NCI-H2073 HLI 373 CTRP1 0.2604 33.3330
NCI-H2073 idarubicin CTRP1 0.0020 0.2600
NCI-H2073 indisulam CTRP1 0.2604 33.3330
NCI-H2073 isoevodiamine CTRP1 0.2604 33.3330
NCI-H2073 isoliquiritigenin CTRP1 0.2604 33.3330
NCI-H2073 itraconazole CTRP1 0.2604 33.3330
NCI-H2073 JQ1 CTRP1 0.0781 10.0000
NCI-H2073 JZL-184 CTRP1 0.2891 37.0000
NCI-H2073 kahalalide F CTRP1 0.2604 33.3330
NCI-H2073 kinetin riboside CTRP1 0.2604 33.3330
NCI-H2073 Ko-143 CTRP1 1.0417 133.3300
NCI-H2073 LDN-193189 CTRP1 0.2604 33.3330
NCI-H2073 LE-135 CTRP1 0.5208 66.6670
NCI-H2073 Lenalidomide CTRP1 4.6250 592.0000
NCI-H2073 leucascandrolide A CTRP1 0.0163 2.0833
NCI-H2073 LFM-A13 CTRP1 2.8935 370.3700
NCI-H2073 Linsitinib CTRP1 0.2604 33.3330
NCI-H2073 lonidamine CTRP1 4.6250 592.0000
NCI-H2073 losartan CTRP1 4.1667 533.3300
NCI-H2073 lovastatin acid CTRP1 1.0417 133.3300
NCI-H2073 LY-2183240 CTRP1 0.2604 33.3330
NCI-H2073 m-3M3-FBS CTRP1 2.0833 266.6700
NCI-H2073 manumycin A CTRP1 0.2365 30.2680
NCI-H2073 maraviroc CTRP1 0.2604 33.3330
NCI-H2073 MDV-3100 CTRP1 0.0065 0.8333
NCI-H2073 Merck60 CTRP1 0.2604 33.3330
NCI-H2073 minoxidil CTRP1 0.2604 33.3330
NCI-H2073 MK-1775 CTRP1 0.2604 33.3330
NCI-H2073 MK-591 CTRP1 2.0833 266.6700
NCI-H2073 ML006 CTRP1 4.1667 533.3300
NCI-H2073 ML007 CTRP1 0.2891 37.0000
NCI-H2073 ML013 CTRP1 0.5208 66.6670
NCI-H2073 ML030 CTRP1 0.0090 1.1533
NCI-H2073 ML050 CTRP1 0.5208 66.6670
NCI-H2073 ML100 CTRP1 0.2604 33.3330
NCI-H2073 ML101 CTRP1 2.0833 266.6700
NCI-H2073 ML150 CTRP1 0.2604 33.3330
NCI-H2073 ML159 CTRP1 1.0417 133.3300
NCI-H2073 ML160 CTRP1 1.0417 133.3300
NCI-H2073 ML162 CTRP1 0.2604 33.3330
NCI-H2073 ML203 CTRP1 2.3125 296.0000
NCI-H2073 ML210 CTRP1 0.2604 33.3330
NCI-H2073 ML214 CTRP1 0.2604 33.3330
NCI-H2073 MPEP CTRP1 0.2604 33.3330
NCI-H2073 myriocin CTRP1 0.2604 33.3330
NCI-H2073 N-oxalyl-D-phenylalanine CTRP1 4.1667 533.3300
NCI-H2073 N9-isopropylolomoucine CTRP1 3.1914 408.5000
NCI-H2073 nakiterpiosin CTRP1 0.2604 33.3330
NCI-H2073 Navitoclax CTRP1 0.2604 33.3330
NCI-H2073 necrostatin-1 CTRP1 4.1667 533.3300
NCI-H2073 neopeltolide CTRP1 0.0000 1.1533
NCI-H2073 neratinib CTRP1 0.2604 33.3330
NCI-H2073 nifedipine CTRP1 0.2604 33.3330
NCI-H2073 nimodipine CTRP1 0.2604 33.3330
NCI-H2073 NPC-26 CTRP1 0.3125 40.0000
NCI-H2073 NSC 74859 CTRP1 4.1667 533.3300
NCI-H2073 NSC23766 CTRP1 4.1667 533.3300
NCI-H2073 NSC632839 CTRP1 0.2604 33.3330
NCI-H2073 NSC95397 CTRP1 0.2604 33.3330
NCI-H2073 Nutlin-3a CTRP1 1.1562 148.0000
NCI-H2073 NVP-AUY922 CTRP1 0.0001 33.3330
NCI-H2073 Olaparib CTRP1 1.1562 148.0000
NCI-H2073 oligomycin A CTRP1 0.2604 33.3330
NCI-H2073 orteronel CTRP1 1.0417 133.3300
NCI-H2073 OSW-1 CTRP1 0.0010 16.6670
NCI-H2073 P-0850 CTRP1 0.2604 33.3330
NCI-H2073 PAC-1 CTRP1 0.2604 33.3330
NCI-H2073 panduratin A CTRP1 2.0833 266.6700
NCI-H2073 parbendazole CTRP1 0.0081 66.6670
NCI-H2073 Parthenolide CTRP1 0.5208 66.6670
NCI-H2073 PDMP CTRP1 1.6667 213.3300
NCI-H2073 Pemetrexed CTRP1 2.3125 296.0000
NCI-H2073 penfluridol CTRP1 0.7813 100.0000
NCI-H2073 Pevonedistat CTRP1 0.2891 37.0000
NCI-H2073 PF-04217903 CTRP1 1.0417 133.3300
NCI-H2073 PF-3845 CTRP1 0.2604 33.3330
NCI-H2073 PF-750 CTRP1 2.0833 266.6700
NCI-H2073 phloretin CTRP1 4.6250 592.0000
NCI-H2073 PI-103 CTRP1 0.2891 37.0000
NCI-H2073 pifithrin-alpha CTRP1 1.8185 232.7700
NCI-H2073 pifithrin-mu CTRP1 0.2604 33.3330
NCI-H2073 PIK-75 CTRP1 0.0023 0.2890
NCI-H2073 Piperlongumine CTRP1 0.2604 35.6930
NCI-H2073 PK-11195 CTRP1 4.1667 533.3300
NCI-H2073 PNU-74654 CTRP1 2.0833 266.6700
NCI-H2073 PP-30 CTRP1 0.2891 37.0000
NCI-H2073 PRIMA-1 CTRP1 1.1562 148.0000
NCI-H2073 PRIMA-1MET CTRP1 0.2604 33.3330
NCI-H2073 PRL-3 Inhibitor I CTRP1 1.0417 133.3300
NCI-H2073 PT-630 CTRP1 0.2604 33.3330
NCI-H2073 purmorphamine CTRP1 1.1562 148.0000
NCI-H2073 PX-12 CTRP1 0.7813 100.0000
NCI-H2073 pyrvinium pamoate CTRP1 0.2604 33.3330
NCI-H2073 QS11 CTRP1 0.2604 33.3330
NCI-H2073 quinoclamine CTRP1 0.2891 37.0000
NCI-H2073 Rapamycin CTRP1 0.2891 37.0000
NCI-H2073 RG-108 CTRP1 2.0833 266.6700
NCI-H2073 RITA CTRP1 0.2604 33.3330
NCI-H2073 Ro-28-1675 CTRP1 4.1667 533.3300
NCI-H2073 rosiglitazone CTRP1 2.0833 266.6700
NCI-H2073 rotenone CTRP1 0.0163 2.0833
NCI-H2073 RS-23597-190 CTRP1 4.1667 533.3300
NCI-H2073 salermide CTRP1 3.1250 400.0000
NCI-H2073 SB-225002 CTRP1 0.2891 37.0000
NCI-H2073 SCH-529074 CTRP1 0.2604 33.3330
NCI-H2073 SCH-79797 CTRP1 0.2891 37.0000
NCI-H2073 Selisistat CTRP1 0.6250 80.0000
NCI-H2073 Selumetinib CTRP1 2.0833 266.6700
NCI-H2073 Sepantronium bromide CTRP1 0.0081 1.0417
NCI-H2073 Serdemetan CTRP1 0.2604 33.3330
NCI-H2073 SID 26681509 CTRP1 2.3125 296.0000
NCI-H2073 sildenafil CTRP1 4.1667 533.3300
NCI-H2073 simvastatin CTRP1 0.2604 33.3330
NCI-H2073 SJ-172550 CTRP1 0.2891 37.0000
NCI-H2073 SKI-II CTRP1 1.0417 133.3300
NCI-H2073 SN-38 CTRP1 0.0090 1.1533
NCI-H2073 SNX-2112 CTRP1 0.0020 0.2600
NCI-H2073 sparfosic acid CTRP1 2.0833 266.6700
NCI-H2073 SR-II-138A CTRP1 0.0020 0.2600
NCI-H2073 T-5345967 CTRP1 4.1667 533.3300
NCI-H2073 tacrolimus CTRP1 0.5781 74.0000
NCI-H2073 tamatinib CTRP1 0.2604 33.3330
NCI-H2073 Tamoxifen CTRP1 0.7393 94.6330
NCI-H2073 Tanespimycin CTRP1 0.0090 1.1533
NCI-H2073 Telomerase Inhibitor IX CTRP1 0.2891 37.0000
NCI-H2073 Teniposide CTRP1 0.0326 4.1667
NCI-H2073 TGX-115 CTRP1 4.1667 533.3300
NCI-H2073 tipifarnib-P1 CTRP1 0.2604 33.3330
NCI-H2073 tipifarnib-P2 CTRP1 0.2604 33.3330
NCI-H2073 Tivozanib CTRP1 0.2604 33.3330
NCI-H2073 tosedostat CTRP1 2.0833 266.6700
NCI-H2073 Tozasertib CTRP1 0.2604 33.3330
NCI-H2073 Tretinoin CTRP1 1.0417 133.3300
NCI-H2073 triacsin C CTRP1 0.2604 33.3330
NCI-H2073 trifluoperazine CTRP1 0.2604 33.3330
NCI-H2073 triptolide CTRP1 0.0020 0.2600
NCI-H2073 TTNBP CTRP1 0.0260 3.3333
NCI-H2073 Tubastatin A CTRP1 0.2604 33.3330
NCI-H2073 TW 37 CTRP1 0.2604 33.3330
NCI-H2073 tyrphostin AG-1478 CTRP1 1.4787 189.2800
NCI-H2073 ubistatin B CTRP1 4.1667 533.3300
NCI-H2073 UNC0638 CTRP1 0.2604 33.3330
NCI-H2073 ursolic acid CTRP1 1.8247 233.5600
NCI-H2073 valdecoxib CTRP1 4.6250 592.0000
NCI-H2073 VER-155008 CTRP1 0.2891 37.0000
NCI-H2073 Vismodegib CTRP1 0.2604 33.3330
NCI-H2073 Vorinostat CTRP1 0.2891 37.0000
NCI-H2073 WT-161 CTRP1 0.2604 33.3330
NCI-H2073 XAV939 CTRP1 0.2891 37.0000
NCI-H2073 zebularine CTRP1 4.6250 592.0000
NCI-H2073 zileuton CTRP1 4.1667 533.3300
NCI-H2073 ZM336372 CTRP1 2.6747 342.3700

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC