Cell Line : SCLC-21H

Cellosaurus Index : CVCL_0024
Cellosaurus ID : SCLC-21H

CCLE Name : SCLC21H_LUNG
CTRP1 Name , CTRP2 Name : SCLC21H

Cancer Type : lung
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
SCLC-21H (-)-gallocatechin-3-monogallate CTRP1 2.3125 296.0000
SCLC-21H 16-beta-bromoandrosterone CTRP1 0.2891 37.0000
SCLC-21H 16,16-dimethylprostaglandin-E2 CTRP1 0.1302 33.3330
SCLC-21H 1S,3R-RSL-3 CTRP1 0.0156 4.0000
SCLC-21H 2-bromopyruvate CTRP1 4.1667 533.3300
SCLC-21H 2-fluoropalmitic acid CTRP1 0.5781 148.0000
SCLC-21H 2,4-dideoxy-DC-45-A2 CTRP1 0.0163 2.0833
SCLC-21H 3-chloro-L-alanine CTRP1 0.0163 2.0833
SCLC-21H 4-IPP CTRP1 1.0417 133.3300
SCLC-21H 4-methylfasudil CTRP1 1.0417 133.3300
SCLC-21H 6-diazo-5-oxo-L-norleucine CTRP1 1.0417 133.3300
SCLC-21H 7-nitroindazole CTRP1 2.0833 266.6700
SCLC-21H AA-COCF3 CTRP1 2.0833 266.6700
SCLC-21H ABT-751 CTRP1 0.2604 33.3330
SCLC-21H ABT737 CTRP1 0.2891 37.0000
SCLC-21H AC55649 CTRP1 0.2604 33.3330
SCLC-21H AGK-2 CTRP1 0.2604 33.3330
SCLC-21H Alda-1 CTRP1 1.0417 133.3300
SCLC-21H AM-580 CTRP1 4.1667 533.3300
SCLC-21H ASN 05257430 CTRP1 0.1445 37.0000
SCLC-21H AT13387 CTRP2 0.0020 66.0000
SCLC-21H austocystin D CTRP1 0.2891 37.0000
SCLC-21H avrainvillamide CTRP1 0.2604 33.3330
SCLC-21H AZD-7545 CTRP1 0.5781 74.0000
SCLC-21H AZD8055 CTRP2 0.0020 33.0000
SCLC-21H batimastat CTRP1 1.1562 148.0000
SCLC-21H Bax channel blocker CTRP1 0.2604 33.3330
SCLC-21H BEC CTRP1 2.0833 266.6700
SCLC-21H BI-2536 CTRP2,CTRP1 0.0010 33.3330
SCLC-21H BIBR-1532 CTRP1 2.0833 266.6700
SCLC-21H BIX-01294 CTRP2,CTRP1 0.0010 33.3330
SCLC-21H blebbistatin CTRP1 1.0417 133.3300
SCLC-21H BML-259 CTRP1 2.0833 266.6700
SCLC-21H BMS-191011 CTRP1 0.2604 33.3330
SCLC-21H BMS-299897 CTRP1 0.2604 33.3330
SCLC-21H BMS-536924 CTRP1 0.2891 37.0000
SCLC-21H BMS-641988 CTRP1 0.2891 37.0000
SCLC-21H BMS-754807 CTRP1 0.2604 33.3330
SCLC-21H Bortezomib CTRP1 0.0010 0.1300
SCLC-21H BRD0713 CTRP1 0.6250 80.0000
SCLC-21H BRD1812 CTRP1 0.2604 33.3330
SCLC-21H BRD2572 CTRP1 0.3125 80.0000
SCLC-21H BRD2762 CTRP1 0.6250 80.0000
SCLC-21H BRD4046 CTRP1 0.6250 80.0000
SCLC-21H BRD4372 CTRP1 0.6250 80.0000
SCLC-21H BRD4770 CTRP1 0.2604 33.3330
SCLC-21H BRD55319 CTRP1 0.2891 37.0000
SCLC-21H BRD5802 CTRP1 0.6250 80.0000
SCLC-21H BRD6150 CTRP1 0.3125 80.0000
SCLC-21H BRD63610 CTRP1 0.0081 1.0417
SCLC-21H BRD6368 CTRP1 0.2604 33.3330
SCLC-21H BRD6825 CTRP1 0.6250 80.0000
SCLC-21H BRD7137 CTRP1 0.2604 33.3330
SCLC-21H BRD8097 CTRP1 0.6250 80.0000
SCLC-21H BRD8418 CTRP1 0.6250 80.0000
SCLC-21H BRD8958 CTRP1 0.2604 66.6670
SCLC-21H BRD9658 CTRP1 0.6250 80.0000
SCLC-21H brefeldin A CTRP1 0.0023 0.2890
SCLC-21H BX795 CTRP1 0.2604 33.3330
SCLC-21H capsaicin CTRP1 4.1667 533.3300
SCLC-21H CAY10594 CTRP1 4.1667 533.3300
SCLC-21H CCT036477 CTRP1 0.2604 33.3330
SCLC-21H CD-1530 CTRP1 1.0417 133.3300
SCLC-21H CD-437 CTRP1 0.2891 37.0000
SCLC-21H cerulenin CTRP1 1.1562 148.0000
SCLC-21H chaetocin CTRP1 0.0020 0.2600
SCLC-21H CHEMBL1222381 CTRP1 2.0833 266.6700
SCLC-21H CHEMBL374350 CTRP1 0.2604 33.3330
SCLC-21H CHEMBL399379 CTRP1 2.0833 266.6700
SCLC-21H CHIR-99021 CTRP1 0.6250 80.0000
SCLC-21H CHM-1 CTRP1 0.1250 16.0000
SCLC-21H CI-976 CTRP1 2.0833 266.6700
SCLC-21H ciclosporin CTRP1 0.2604 33.3330
SCLC-21H CID 2853753 CTRP1 0.2604 33.3330
SCLC-21H CIL41 CTRP1 1.2500 160.0000
SCLC-21H CIL55 CTRP1 1.2500 160.0000
SCLC-21H CIL55A CTRP1 0.6250 80.0000
SCLC-21H CIL56 CTRP1 0.3125 40.0000
SCLC-21H CIL70 CTRP1 0.1562 40.0000
SCLC-21H Compound 10b CTRP1 1.1562 148.0000
SCLC-21H Compound 110 CTRP1 0.5781 74.0000
SCLC-21H Compound 12 CTRP1 0.2891 37.0000
SCLC-21H Compound 1541A CTRP1 0.2891 37.0000
SCLC-21H Compound 23 citrate CTRP1 0.2604 33.3330
SCLC-21H Compound 4 CTRP1 0.2604 33.3330
SCLC-21H Compound 44 CTRP1 1.0417 133.3300
SCLC-21H Compound 7d-cis CTRP1 0.2604 33.3330
SCLC-21H CR-1-31B CTRP2,CTRP1 0.0010 33.3330
SCLC-21H cyanoquinoline 11 CTRP1 1.0417 133.3300
SCLC-21H cytochalasin B CTRP1 0.2604 33.3330
SCLC-21H cytosporone B CTRP1 0.2604 33.3330
SCLC-21H Dactolisib CTRP1 0.0163 2.0833
SCLC-21H dalcetrapib CTRP1 2.0687 264.8000
SCLC-21H Daporinad CTRP1 0.0020 0.2600
SCLC-21H DC-45-A2 CTRP1 0.2891 37.0000
SCLC-21H dexamethasone CTRP1 0.2604 33.3330
SCLC-21H DG-041 CTRP1 0.5208 133.3300
SCLC-21H Dinaciclib CTRP2 0.0020 66.0000
SCLC-21H DL-TBOA CTRP1 4.1667 533.3300
SCLC-21H ELCPK CTRP1 0.0031 0.4000
SCLC-21H endo-IWR-1 CTRP1 0.1302 33.3330
SCLC-21H erastin CTRP1 0.1250 16.0000
SCLC-21H erastin-A8 CTRP1 0.1250 16.0000
SCLC-21H etomoxir CTRP1 2.3125 296.0000
SCLC-21H Etoposide CTRP1 0.2212 28.3180
SCLC-21H fatostatin CTRP1 0.2604 33.3330
SCLC-21H Fedratinib CTRP1 0.2891 37.0000
SCLC-21H FGIN-1-27 CTRP1 0.2604 33.3330
SCLC-21H fluoropyruvate CTRP1 1.1562 148.0000
SCLC-21H Flutamide CTRP1 0.7542 96.5330
SCLC-21H FQI-1 CTRP1 0.2604 33.3330
SCLC-21H FQI-2 CTRP1 0.2604 33.3330
SCLC-21H fumagillol CTRP1 4.1667 533.3300
SCLC-21H Gemcitabine CTRP1 0.0020 0.2600
SCLC-21H glibenclamide CTRP1 0.2604 33.3330
SCLC-21H Gly-Gly-PALO CTRP1 2.0833 266.6700
SCLC-21H GMX-1778 CTRP1 0.0020 0.2600
SCLC-21H gossypol CTRP1 0.2891 37.0000
SCLC-21H GW-405833 CTRP1 1.0417 133.3300
SCLC-21H GW843682X CTRP1 0.2604 33.3330
SCLC-21H HLI 373 CTRP1 0.2604 33.3330
SCLC-21H idarubicin CTRP1 0.0020 0.2600
SCLC-21H indisulam CTRP1 0.2604 33.3330
SCLC-21H isoevodiamine CTRP1 0.2604 33.3330
SCLC-21H isoliquiritigenin CTRP1 0.1302 33.3330
SCLC-21H itraconazole CTRP1 0.2604 33.3330
SCLC-21H JZL-184 CTRP1 0.2891 37.0000
SCLC-21H kahalalide F CTRP1 0.1302 33.3330
SCLC-21H kinetin riboside CTRP1 0.2604 33.3330
SCLC-21H Ko-143 CTRP1 1.0417 133.3300
SCLC-21H LDN-193189 CTRP1 0.2604 33.3330
SCLC-21H LE-135 CTRP1 0.5208 66.6670
SCLC-21H Lenalidomide CTRP1 4.6250 592.0000
SCLC-21H leptomycin B CTRP2 0.0020 66.0000
SCLC-21H leucascandrolide A CTRP1 0.0163 2.0833
SCLC-21H LFM-A13 CTRP1 2.8935 370.3700
SCLC-21H Linsitinib CTRP1 0.1302 33.3330
SCLC-21H lonidamine CTRP1 4.6250 592.0000
SCLC-21H losartan CTRP1 4.1667 533.3300
SCLC-21H lovastatin acid CTRP1 1.0417 133.3300
SCLC-21H LY-2183240 CTRP1 0.2604 33.3330
SCLC-21H m-3M3-FBS CTRP1 2.0833 266.6700
SCLC-21H manumycin A CTRP1 0.2365 30.2680
SCLC-21H maraviroc CTRP1 0.2604 33.3330
SCLC-21H Merck60 CTRP1 0.2604 33.3330
SCLC-21H MK-1775 CTRP1 0.2604 33.3330
SCLC-21H MK-591 CTRP1 2.0833 266.6700
SCLC-21H ML006 CTRP1 4.1667 533.3300
SCLC-21H ML007 CTRP1 0.2891 37.0000
SCLC-21H ML013 CTRP1 0.2604 66.6670
SCLC-21H ML030 CTRP2,CTRP1 0.0020 66.0000
SCLC-21H ML050 CTRP1 0.2604 66.6670
SCLC-21H ML100 CTRP1 0.1302 33.3330
SCLC-21H ML101 CTRP1 2.0833 266.6700
SCLC-21H ML150 CTRP1 0.2604 33.3330
SCLC-21H ML159 CTRP1 1.0417 133.3300
SCLC-21H ML160 CTRP1 1.0417 133.3300
SCLC-21H ML162 CTRP1 0.2604 33.3330
SCLC-21H ML203 CTRP1 2.3125 296.0000
SCLC-21H ML210 CTRP1 0.2604 33.3330
SCLC-21H myriocin CTRP1 0.2604 33.3330
SCLC-21H N-oxalyl-D-phenylalanine CTRP1 4.1667 533.3300
SCLC-21H N9-isopropylolomoucine CTRP1 3.1914 408.5000
SCLC-21H nakiterpiosin CTRP1 0.2604 33.3330
SCLC-21H Navitoclax CTRP1 0.2604 33.3330
SCLC-21H necrostatin-1 CTRP1 4.1667 533.3300
SCLC-21H neopeltolide CTRP1 0.0000 1.1533
SCLC-21H neratinib CTRP1 0.2604 33.3330
SCLC-21H nifedipine CTRP1 0.2604 33.3330
SCLC-21H NPC-26 CTRP1 0.3125 40.0000
SCLC-21H NSC 74859 CTRP1 4.1667 533.3300
SCLC-21H NSC23766 CTRP1 4.1667 533.3300
SCLC-21H NSC632839 CTRP1 0.2604 33.3330
SCLC-21H NSC95397 CTRP1 0.2604 33.3330
SCLC-21H Nutlin-3a CTRP1 1.1562 148.0000
SCLC-21H NVP-AUY922 CTRP1 0.0001 33.3330
SCLC-21H Olaparib CTRP1 1.1562 148.0000
SCLC-21H oligomycin A CTRP2,CTRP1 0.0010 33.3330
SCLC-21H orteronel CTRP1 0.5208 133.3300
SCLC-21H OSW-1 CTRP1 0.0010 16.6670
SCLC-21H ouabain CTRP2 0.0081 270.0000
SCLC-21H P-0850 CTRP1 0.2604 33.3330
SCLC-21H PAC-1 CTRP1 0.2604 33.3330
SCLC-21H Paclitaxel CTRP2 0.0020 66.0000
SCLC-21H panduratin A CTRP1 2.0833 266.6700
SCLC-21H parbendazole CTRP1 0.0081 66.6670
SCLC-21H Parthenolide CTRP1 4.1667 533.3300
SCLC-21H PDMP CTRP1 1.6667 213.3300
SCLC-21H Pemetrexed CTRP1 2.3125 296.0000
SCLC-21H Pevonedistat CTRP1 0.2891 37.0000
SCLC-21H PF-04217903 CTRP1 1.0417 133.3300
SCLC-21H PF-3758309 CTRP2 0.0020 66.0000
SCLC-21H PF-3845 CTRP1 0.2604 33.3330
SCLC-21H PF-750 CTRP1 2.0833 266.6700
SCLC-21H phloretin CTRP1 4.6250 592.0000
SCLC-21H PI-103 CTRP1 0.2891 37.0000
SCLC-21H pifithrin-alpha CTRP1 1.8185 232.7700
SCLC-21H pifithrin-mu CTRP1 0.2604 33.3330
SCLC-21H PIK-75 CTRP1 0.0023 0.2890
SCLC-21H Piperlongumine CTRP1 0.2604 33.3330
SCLC-21H PK-11195 CTRP1 4.1667 533.3300
SCLC-21H PNU-74654 CTRP1 2.0833 266.6700
SCLC-21H PP-30 CTRP1 0.2891 37.0000
SCLC-21H PRIMA-1 CTRP1 1.1562 148.0000
SCLC-21H PRIMA-1MET CTRP1 0.2604 33.3330
SCLC-21H PRL-3 Inhibitor I CTRP1 1.0417 133.3300
SCLC-21H PT-630 CTRP1 0.1302 33.3330
SCLC-21H purmorphamine CTRP1 1.1562 148.0000
SCLC-21H pyrvinium pamoate CTRP1 0.2604 33.3330
SCLC-21H QS11 CTRP1 0.2604 33.3330
SCLC-21H quinoclamine CTRP1 0.2891 37.0000
SCLC-21H Rapamycin CTRP1 0.2891 37.0000
SCLC-21H RG-108 CTRP1 2.0833 266.6700
SCLC-21H RITA CTRP1 0.2604 33.3330
SCLC-21H Ro-28-1675 CTRP1 4.1667 533.3300
SCLC-21H rosiglitazone CTRP1 2.0833 266.6700
SCLC-21H rotenone CTRP1 0.0163 2.0833
SCLC-21H RS-23597-190 CTRP1 4.1667 533.3300
SCLC-21H SB-225002 CTRP1 0.2891 37.0000
SCLC-21H SB-743921 CTRP2 0.0010 33.0000
SCLC-21H SCH-529074 CTRP1 0.2604 33.3330
SCLC-21H SCH-79797 CTRP1 0.2891 37.0000
SCLC-21H Selisistat CTRP1 0.6250 80.0000
SCLC-21H Selumetinib CTRP1 2.0833 266.6700
SCLC-21H selumetinib:JQ-1 (4:1 mol-mol) CTRP2 0.0051 170.0000
SCLC-21H Sepantronium bromide CTRP1 0.0081 1.0417
SCLC-21H Serdemetan CTRP1 0.2604 33.3330
SCLC-21H SID 26681509 CTRP1 2.3125 296.0000
SCLC-21H sildenafil CTRP1 4.1667 533.3300
SCLC-21H simvastatin CTRP1 0.2604 33.3330
SCLC-21H SJ-172550 CTRP1 0.1445 37.0000
SCLC-21H SKI-II CTRP1 1.0417 133.3300
SCLC-21H SN-38 CTRP1 0.0090 1.1533
SCLC-21H SNX-2112 CTRP2,CTRP1 0.0010 8.3000
SCLC-21H sparfosic acid CTRP1 2.0833 266.6700
SCLC-21H SR-II-138A CTRP1 0.0020 0.2600
SCLC-21H T-5345967 CTRP1 4.1667 533.3300
SCLC-21H tacrolimus CTRP1 0.2891 74.0000
SCLC-21H tamatinib CTRP1 0.2604 33.3330
SCLC-21H Tamoxifen CTRP1 0.7393 94.6330
SCLC-21H Tanespimycin CTRP1 0.0090 1.1533
SCLC-21H Telomerase Inhibitor IX CTRP1 0.2891 37.0000
SCLC-21H Teniposide CTRP1 0.0326 4.1667
SCLC-21H TGX-115 CTRP1 4.1667 533.3300
SCLC-21H tipifarnib-P1 CTRP1 0.2604 33.3330
SCLC-21H tipifarnib-P2 CTRP1 0.2604 33.3330
SCLC-21H Tivozanib CTRP1 0.2604 33.3330
SCLC-21H tosedostat CTRP1 2.0833 266.6700
SCLC-21H Tozasertib CTRP1 0.2604 33.3330
SCLC-21H Tretinoin CTRP1 1.0417 133.3300
SCLC-21H triacsin C CTRP1 0.2604 33.3330
SCLC-21H triptolide CTRP1 0.0020 0.2600
SCLC-21H TTNBP CTRP1 0.0260 3.3333
SCLC-21H Tubastatin A CTRP1 0.2604 33.3330
SCLC-21H TW 37 CTRP1 0.1302 33.3330
SCLC-21H tyrphostin AG-1478 CTRP1 1.4787 189.2800
SCLC-21H ubistatin B CTRP1 4.1667 533.3300
SCLC-21H UNC0638 CTRP1 0.2604 33.3330
SCLC-21H ursolic acid CTRP1 1.8247 233.5600
SCLC-21H valdecoxib CTRP1 4.6250 592.0000
SCLC-21H VER-155008 CTRP1 0.2891 37.0000
SCLC-21H Vincristine CTRP2 0.0041 130.0000
SCLC-21H Vismodegib CTRP1 0.2604 33.3330
SCLC-21H Vorinostat CTRP1 0.2891 37.0000
SCLC-21H WT-161 CTRP1 0.2604 33.3330
SCLC-21H XAV939 CTRP1 0.2891 37.0000
SCLC-21H zebularine CTRP1 4.6250 592.0000
SCLC-21H zileuton CTRP1 4.1667 533.3300
SCLC-21H ZM336372 CTRP1 2.6747 342.3700

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC