Cell Line : SIMA

Cellosaurus Index : CVCL_1695
Cellosaurus ID : SIMA

CCLE Name : SIMA_AUTONOMIC_GANGLIA
CTRP2 Name , GDSC1 Name , GDSC2 Name : SIMA

Cancer Type : autonomic_ganglia
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
SIMA (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
SIMA 123138 GDSC2 0.0010 1.0000
SIMA 123829 GDSC2 0.0030 3.0000
SIMA 150412 GDSC2 0.0030 3.0000
SIMA 1S,3R-RSL-3 CTRP2 0.0010 33.0000
SIMA 3-Cl-AHPC CTRP2 0.0020 66.0000
SIMA 5-azacytidine GDSC2 0.0200 20.0000
SIMA 5-Fluorouracil GDSC1,GDSC2 0.0200 32.0000
SIMA 50869 GDSC2 0.0030 3.0000
SIMA 615590 GDSC2 0.0030 3.0000
SIMA 630600 GDSC2 0.0030 3.0000
SIMA 667880 GDSC2 0.0030 3.0000
SIMA 720427 GDSC2 0.0030 3.0000
SIMA 729189 GDSC2 0.0030 3.0000
SIMA 741909 GDSC2 0.0010 1.0000
SIMA 743380 GDSC2 0.0010 1.0000
SIMA 765771 GDSC2 0.0030 3.0000
SIMA 776928 GDSC2 0.0300 30.0000
SIMA 965-D2 GDSC1 0.0391 10.0000
SIMA 993-D2 GDSC1 0.0391 10.0000
SIMA A-366 GDSC2 0.0100 10.0000
SIMA A-443654 GDSC1 0.0040 1.0240
SIMA A-770041 GDSC1 0.0200 5.1200
SIMA A-83-01 GDSC1 0.0781 20.0000
SIMA AA-COCF3 CTRP2 0.0081 270.0000
SIMA ABT737 GDSC2 0.0100 10.0000
SIMA AC55649 CTRP2 0.0010 33.0000
SIMA Acetalax GDSC2 0.0300 30.0000
SIMA ACY-1215 GDSC1 0.0781 20.0000
SIMA AEW541 CCLE 0.0025 8.0000
SIMA Afatinib GDSC1,GDSC2 0.0020 10.0000
SIMA Afuresertib GDSC2 0.0100 10.0000
SIMA AGI-5198 GDSC2 0.0100 10.0000
SIMA AGI-6780 GDSC1,GDSC2 0.0020 10.0000
SIMA AGK-2 GDSC2 0.0040 4.0000
SIMA AICA Ribonucleotide GDSC1 7.8125 2000.0000
SIMA AKT inhibitor VIII GDSC1 0.0100 10.2400
SIMA Alectinib GDSC1 0.0200 5.1200
SIMA Alisertib GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA Alpelisib GDSC2 0.0050 5.0000
SIMA alpha-lipoic acid GDSC2 0.1211 121.0000
SIMA AMG-319 GDSC2 0.0100 10.0000
SIMA Amuvatinib GDSC1 0.0781 20.0000
SIMA apicidin CTRP2 0.0010 33.0000
SIMA Apitolisib GDSC1 0.0781 20.0000
SIMA AR-42 GDSC1 0.0200 5.1200
SIMA Ara-G GDSC1 0.0781 20.0000
SIMA ARRY-520 GDSC1 0.0010 0.2560
SIMA AS601245 GDSC1 0.0312 8.0000
SIMA AS605240 GDSC1 0.0781 20.0000
SIMA ascorbate (vitamin C) GDSC2 2.0011 2000.0000
SIMA AST-1306 GDSC1 0.0781 20.0000
SIMA AT-7519 GDSC1 0.0400 10.2400
SIMA AT13148 GDSC2 0.0100 10.0000
SIMA AT7867 GDSC1,CTRP2 0.0020 66.0000
SIMA Avagacestat GDSC1,GDSC2 0.0100 10.2400
SIMA Axitinib GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA AZ20 GDSC1 0.0391 10.0000
SIMA AZ6102 GDSC2 0.0100 10.0000
SIMA AZ628 GDSC1 0.0156 4.0000
SIMA AZ960 GDSC2 0.0100 10.0000
SIMA AZD1208 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD1332 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD1480 GDSC1 0.0098 2.5000
SIMA AZD2014 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD3514 GDSC1 0.0391 10.0000
SIMA AZD3759 GDSC2 0.0010 1.0000
SIMA AZD4547 GDSC1,GDSC2,CTRP2 0.0010 66.0000
SIMA AZD4877 GDSC1 0.0002 0.0390
SIMA AZD5153 GDSC2 0.0100 10.0000
SIMA AZD5363 GDSC2 0.0100 10.0000
SIMA AZD5438 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD5582 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD5991 GDSC2 0.0100 10.0000
SIMA AZD6094 GDSC1 0.0098 2.5000
SIMA AZD6482 GDSC1 0.0195 5.1200
SIMA AZD6738 GDSC1,GDSC2 0.0100 10.0000
SIMA AZD7762 GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA AZD7969 GDSC1 0.0391 10.0000
SIMA AZD8055 GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA AZD8186 GDSC1,GDSC2 0.0098 10.0000
SIMA AZD8835 GDSC1 0.0391 10.0000
SIMA AZD8931 GDSC1 0.0391 10.0000
SIMA BAM7 GDSC1 0.0781 20.0000
SIMA barasertib CTRP2 0.0020 66.0000
SIMA BAY ACCi GDSC1 0.0391 10.0000
SIMA BAY AKT1 GDSC1 0.0391 10.0000
SIMA BAY-61-3606 GDSC1 0.0312 8.0000
SIMA BAY-HDAC11_1 GDSC1 0.0391 10.0000
SIMA BAY-HDAC11_2 GDSC1 0.0391 10.0000
SIMA BAY-HDAC11_4 GDSC1 0.0391 10.0000
SIMA BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
SIMA BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
SIMA BAY-MPS1 GDSC1 0.0117 3.0000
SIMA BDF00022089a GDSC2 0.0050 5.0000
SIMA BDILV000379a GDSC2 0.0050 5.0000
SIMA BDOCA000347a GDSC2 0.0020 2.0000
SIMA BDP-00009066 GDSC2 0.0100 10.0000
SIMA Belinostat GDSC1 0.0781 20.0000
SIMA BEN GDSC2 0.0300 30.0000
SIMA Bexarotene GDSC1 0.0312 8.0000
SIMA BI-2536 GDSC1,GDSC2,CTRP2 0.0010 33.0000
SIMA BIBF-1120 GDSC1 0.0781 20.0000
SIMA BIBR-1532 GDSC2,CTRP2 0.0081 270.0000
SIMA Bicalutamide GDSC1 0.0040 10.0000
SIMA birinapant CTRP2 0.0020 66.0000
SIMA BIX02189 GDSC1 0.0781 20.0000
SIMA blebbistatin CTRP2 0.0041 130.0000
SIMA Bleomycin GDSC1,GDSC2 0.0020 64.0000
SIMA Bleomycin (10 uM) GDSC1 0.0391 10.0000
SIMA Bleomycin (50 uM) GDSC1,GDSC2 0.0400 50.0000
SIMA bleomycin A2 CTRP2 0.0020 66.0000
SIMA BMS-345541 GDSC1,GDSC2 0.0100 16.0000
SIMA BMS-509744 GDSC1 0.0400 10.2400
SIMA BMS-536924 GDSC1,GDSC2,CTRP2 0.0011 37.0000
SIMA BMS-754807 GDSC1,GDSC2,CTRP2 0.0010 33.0000
SIMA Bortezomib GDSC1,GDSC2,CTRP2 0.0000 0.1300
SIMA Bosutinib GDSC1,GDSC2 0.0020 2.0000
SIMA BPD-00008900 GDSC2 0.0100 10.0000
SIMA BPTES GDSC1 0.0391 10.0000
SIMA BRD-K03911514 CTRP2 0.0020 66.0000
SIMA BRD-K04800985 CTRP2 0.0020 66.0000
SIMA BRD-K09587429 CTRP2 0.0020 66.0000
SIMA BRD-K13185470 CTRP2 0.0020 66.0000
SIMA BRD-K16147474 CTRP2 0.0020 66.0000
SIMA BRD-K20514654 CTRP2 0.0020 66.0000
SIMA BRD-K27224038 CTRP2 0.0020 66.0000
SIMA BRD-K29086754 CTRP2 0.0020 66.0000
SIMA BRD-K33199242 CTRP2 0.0020 66.0000
SIMA BRD-K34222889 CTRP2 0.0020 66.0000
SIMA BRD-K66532283 CTRP2 0.0020 66.0000
SIMA BRD-K70511574 CTRP2 0.0020 66.0000
SIMA BRD-K71781559 CTRP2 0.0020 66.0000
SIMA BRD-K85133207 CTRP2 0.0020 66.0000
SIMA BRD-K88742110 CTRP2 0.0020 66.0000
SIMA BRD-K96970199 CTRP2 0.0020 66.0000
SIMA BRD-K97651142 CTRP2 0.0020 66.0000
SIMA BRD6340 CTRP2 0.0010 33.0000
SIMA BRD9876 CTRP2 0.0041 130.0000
SIMA brefeldin A CTRP2 0.0011 37.0000
SIMA Brivanib, BMS-540215 GDSC1 0.0781 20.0000
SIMA Bromosporine GDSC2 0.0020 2.0000
SIMA Bryostatin 1 GDSC1 0.0000 0.0080
SIMA Buparlisib GDSC2 0.0100 10.0000
SIMA BX-912 GDSC1 0.0400 10.2400
SIMA BX795 GDSC1 0.0195 5.0000
SIMA C-75 GDSC1 0.0781 20.0000
SIMA C6-ceramide CTRP2 0.0020 66.0000
SIMA Cabozantinib GDSC1 0.0200 5.1200
SIMA Camptothecin GDSC2 0.0001 0.1000
SIMA CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
SIMA Capivasertib GDSC1 0.1172 30.0000
SIMA Carboplatin CTRP2 0.0020 66.0000
SIMA carboplatin:etoposide (40:17 mol-mol) CTRP2 0.0014 47.0000
SIMA Carmustine GDSC2 0.0300 30.0000
SIMA CAY10566 GDSC1 0.0100 2.5600
SIMA CAY10594 CTRP2 0.0020 66.0000
SIMA CAY10603 GDSC1 0.0781 20.0000
SIMA CAY10618 CTRP2 0.0010 33.0000
SIMA CCT-018159 GDSC1 0.0391 10.0000
SIMA CCT007093 GDSC1,GDSC2 0.0100 10.0000
SIMA CCT245232 GDSC1 0.0008 0.2000
SIMA CCT245467 GDSC1 0.0008 0.2000
SIMA CD-437 CTRP2 0.0011 37.0000
SIMA CD532 GDSC1 0.0200 5.1200
SIMA CDK9_5038 GDSC2 0.0030 3.0000
SIMA CDK9_5576 GDSC2 0.0100 10.0000
SIMA Cediranib GDSC2 0.0100 10.0000
SIMA ceranib-2 CTRP2 0.0020 66.0000
SIMA cerulenin CTRP2 0.0045 150.0000
SIMA Cetuximab GDSC1 0.2570 65.8000
SIMA CGP-082996 GDSC1 0.0200 5.1200
SIMA CGP-60474 GDSC1 0.0010 0.2560
SIMA CHEMBL374350 CTRP2 0.0010 17.0000
SIMA CHIR-99021 GDSC1,CTRP2 0.0024 80.0000
SIMA CHM-1 CTRP2 0.0005 16.0000
SIMA CI-1033 GDSC1 0.0781 20.0000
SIMA CI-1040 GDSC1 0.0391 10.0000
SIMA CI-976 CTRP2 0.0081 270.0000
SIMA ciclopirox CTRP2 0.0020 66.0000
SIMA CIL41 CTRP2 0.0049 160.0000
SIMA cimetidine CTRP2 0.0081 270.0000
SIMA Cisplatin GDSC1,GDSC2 0.0040 10.0000
SIMA clofarabine CTRP2 0.0020 66.0000
SIMA CMK GDSC1 0.0156 4.0000
SIMA compound 1B CTRP2 0.0020 66.0000
SIMA CP466722 GDSC1 0.0625 16.0000
SIMA CP724714 GDSC1 0.0400 10.2400
SIMA CPI-613 GDSC1 1.0000 256.0000
SIMA CPI-637 GDSC2 0.0100 10.0000
SIMA CR-1-31B CTRP2 0.0010 33.0000
SIMA Crizotinib GDSC1,GDSC2,CTRP2,CCLE 0.0010 66.0000
SIMA crizotinib:PLX-4032 (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA CRT0105446 GDSC1 0.0391 10.0000
SIMA CRT0105950 GDSC1 0.0391 10.0000
SIMA CRT0160829 GDSC1 0.0781 20.0000
SIMA CT7033-2 GDSC2 0.0100 10.0000
SIMA cucurbitacin I CTRP2 0.0010 33.0000
SIMA CUDC-101 GDSC1 0.0200 5.1200
SIMA CX-5461 GDSC1 0.0400 10.2400
SIMA Cyclopamine GDSC1 0.0625 16.0000
SIMA Cyclophosphamide GDSC2 0.0100 10.0000
SIMA Cytarabine GDSC1,GDSC2 0.0020 2.0000
SIMA cytarabine hydrochloride CTRP2 0.0020 66.0000
SIMA CZC24832 GDSC2 0.0100 10.0000
SIMA Dabrafenib GDSC1,GDSC2 0.0100 10.0000
SIMA Dacarbazine GDSC2 0.0200 20.0000
SIMA Dacinostat GDSC1 0.0040 1.0240
SIMA Dactinomycin GDSC2 0.0000 0.8000
SIMA Dactolisib GDSC1,GDSC2 0.0003 0.2500
SIMA Daporinad GDSC1,CTRP2 0.0000 1.0000
SIMA Dasatinib GDSC1,GDSC2 0.0010 2.0000
SIMA Decitabine CTRP2 0.0020 66.0000
SIMA decitabine:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
SIMA decitabine:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA Dihydrorotenone GDSC2 0.0010 1.0000
SIMA Dinaciclib GDSC2 0.0010 1.0000
SIMA DMOG GDSC1 15.6250 4000.0000
SIMA Docetaxel GDSC1,GDSC2 0.0000 3.0000
SIMA docetaxel:tanespimycin (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA Doramapimod GDSC1 0.0391 10.0000
SIMA Doxorubicin GDSC1 0.0040 5.0000
SIMA doxorubicin:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA Dyrk1b_0191 GDSC1 0.0391 10.0000
SIMA eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
SIMA Eg5_9814 GDSC2 0.0001 0.1000
SIMA EHT-1864 GDSC1,GDSC2 0.0100 10.0000
SIMA ELCPK CTRP2 0.0000 0.4000
SIMA Elephantin GDSC2 0.0200 20.0000
SIMA Elesclomol GDSC1 0.0008 0.2000
SIMA Embelin GDSC1 0.1250 32.0000
SIMA Entinostat GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA Entospletinib GDSC2 0.0100 10.0000
SIMA Enzastaurin GDSC1 0.0781 20.0000
SIMA EphB4_9721 GDSC1 0.0391 10.0000
SIMA epigallocatechin-3-monogallate CTRP2 0.0090 300.0000
SIMA Epirubicin GDSC2 0.0010 1.0000
SIMA Epothilone B GDSC1 0.0001 0.0320
SIMA EPZ004777 GDSC2 0.0100 10.0000
SIMA EPZ5676 GDSC2 0.0100 10.0000
SIMA erastin CTRP2 0.0020 66.0000
SIMA ERK_2440 GDSC2 0.0100 10.0000
SIMA ERK_6604 GDSC2 0.0100 10.0000
SIMA Erlotinib GDSC1,GDSC2,CCLE 0.0020 8.0000
SIMA etomoxir CTRP2 0.0090 300.0000
SIMA Etoposide GDSC1,CTRP2 0.0009 28.0000
SIMA ETP-45835 GDSC1 0.0781 20.0000
SIMA Fedratinib GDSC1 0.0400 10.2400
SIMA FEN1_3940 GDSC1 0.0391 10.0000
SIMA FGFR_0939 GDSC1 0.0098 2.5000
SIMA FGFR_3831 GDSC1 0.0391 10.0000
SIMA FH535 GDSC1 0.1250 32.0000
SIMA Flavopiridol GDSC1 0.0100 2.5600
SIMA Fludarabine GDSC2 0.0200 20.0000
SIMA fluorouracil CTRP2 0.0041 130.0000
SIMA fluvastatin CTRP2 0.0020 66.0000
SIMA Foretinib GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA FQI-2 CTRP2 0.0010 33.0000
SIMA FR-180204 GDSC1 0.0781 20.0000
SIMA FS106 GDSC1 0.0391 10.0000
SIMA FS112 GDSC1 0.0195 5.0000
SIMA FSC231 CTRP2 0.0081 270.0000
SIMA FTI-277 GDSC1 0.0040 1.0240
SIMA FTY-720 GDSC1 0.0781 20.0000
SIMA Fulvestrant GDSC1,GDSC2 0.0010 10.0000
SIMA FY012 GDSC1 0.0391 10.0000
SIMA FY026 GDSC1 0.0391 10.0000
SIMA FY069 GDSC1 0.0391 10.0000
SIMA Gallibiscoquinazole GDSC2 0.0010 1.0000
SIMA GANT-61 CTRP2 0.0020 66.0000
SIMA GDC-0879 CTRP2 0.0020 66.0000
SIMA GDC0810 GDSC2 0.0100 10.0000
SIMA Gefitinib GDSC1,GDSC2 0.0020 2.0000
SIMA Gemcitabine GDSC1,GDSC2,CTRP2 0.0001 33.0000
SIMA Genentech Cpd 10 GDSC1 0.0400 10.2400
SIMA glutathione GDSC2 0.6403 640.0000
SIMA GNE-317 GDSC2 0.0100 10.0000
SIMA GNF-2 GDSC1 0.0050 1.2800
SIMA GSK-J4 GDSC1 0.1172 30.0000
SIMA GSK-LSD1 GDSC2 0.0010 1.0000
SIMA GSK-LSD1-2HCl GDSC2 0.0010 1.0000
SIMA GSK1059615 GDSC1 0.0781 20.0000
SIMA GSK1070916 GDSC1 0.0100 2.5600
SIMA GSK1904529A GDSC1,GDSC2 0.0040 10.0000
SIMA GSK2110183B GDSC2 0.0030 3.0000
SIMA GSK2256098C GDSC2 0.0030 3.0000
SIMA GSK2276186C GDSC2 0.0100 10.0000
SIMA GSK2578215A GDSC2 0.0100 10.0000
SIMA GSK2606414 GDSC2 0.0100 10.0000
SIMA GSK269962A GDSC1 0.0098 5.0000
SIMA GSK2801 GDSC2 0.0100 10.0000
SIMA GSK2830371 GDSC2 0.0100 10.0000
SIMA GSK2830371A GDSC2 0.0030 10.0000
SIMA GSK319347A GDSC1 0.0195 5.0000
SIMA GSK3337463A GDSC2 0.0100 10.0000
SIMA GSK343 GDSC2 0.0010 10.0000
SIMA GSK429286A GDSC1 0.0781 20.0000
SIMA GSK461364 CTRP2 0.0020 66.0000
SIMA GSK591 GDSC2 0.0100 10.0000
SIMA GSK626616AC GDSC2 0.0001 0.1000
SIMA GSK650394 GDSC1 0.0625 16.0000
SIMA GSK690693 GDSC1 0.0400 10.2400
SIMA GW-2580 GDSC1 0.0781 20.0000
SIMA GW-405833 CTRP2 0.0041 130.0000
SIMA GW441756 GDSC1 0.0078 2.0000
SIMA GW843682X GDSC1,CTRP2 0.0010 33.0000
SIMA HC-067047 CTRP2 0.0020 66.0000
SIMA HG-5-113-01 GDSC1 0.0391 10.0000
SIMA HG-5-88-01 GDSC1 0.0391 10.0000
SIMA HG6-64-1 GDSC1 0.0200 5.1200
SIMA HKMTI-1-005 GDSC2 0.0100 10.0000
SIMA HLI 373 CTRP2 0.0010 33.0000
SIMA hyperforin CTRP2 0.0020 66.0000
SIMA I-BET-762 GDSC1,GDSC2 0.0100 20.0000
SIMA I-BET151 GDSC1,CTRP2 0.0020 66.0000
SIMA I-BRD9 GDSC2 0.0100 10.0000
SIMA I-CBP112 GDSC1 0.0391 10.0000
SIMA IAP_5620 GDSC1,GDSC2 0.0100 10.0000
SIMA IAP_7638 GDSC1 0.0391 10.0000
SIMA Ibrutinib GDSC2 0.0100 10.0000
SIMA IC-87114 GDSC1,CTRP2 0.0020 66.0000
SIMA ICL-SIRT078 GDSC2 0.0100 10.0000
SIMA ICL1100013 GDSC1 0.0781 20.0000
SIMA Idelalisib GDSC1 0.0781 20.0000
SIMA ifosfamide CTRP2 0.0020 66.0000
SIMA IGF1R_3801 GDSC2 0.0100 10.0000
SIMA IGFR_3801 GDSC1 0.0391 10.0000
SIMA Imatinib GDSC1 0.0078 2.0000
SIMA IMD-0354 GDSC1 0.0781 20.0000
SIMA indisulam CTRP2 0.0010 33.0000
SIMA IOX2 GDSC1 0.0004 0.1000
SIMA IPA-3 GDSC1 0.1250 32.0000
SIMA Ipatasertib GDSC2 0.0100 10.0000
SIMA IRAK4_4710 GDSC2 0.0100 10.0000
SIMA Irinotecan GDSC2,CCLE 0.0025 10.0000
SIMA isoevodiamine CTRP2 0.0010 33.0000
SIMA ISOX CTRP2 0.0010 33.0000
SIMA Ispinesib Mesylate GDSC1 0.0005 0.1280
SIMA itraconazole CTRP2 0.0005 17.0000
SIMA IU1 CTRP2 0.0020 66.0000
SIMA IWP-2 GDSC2 0.0010 1.0000
SIMA JAK_8517 GDSC2 0.0100 10.0000
SIMA JAK1_3715 GDSC1 0.0391 10.0000
SIMA JAK1_8709 GDSC2 0.0100 10.0000
SIMA JAK3_7406 GDSC1 0.0391 10.0000
SIMA JNJ38877605 GDSC1 0.0781 20.0000
SIMA JNK Inhibitor VIII GDSC1 0.0391 10.0000
SIMA JNK-9L GDSC1 0.0200 5.1200
SIMA JQ-1:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
SIMA JQ-1:MK-0752 (1:1 mol-mol) CTRP2 0.0020 66.0000
SIMA JQ-1:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA JQ-1:UNC0638 (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA JQ-1:vorinostat (2:1 mol-mol) CTRP2 0.0015 50.0000
SIMA JQ1 GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA JQ12 GDSC1 0.0200 5.1200
SIMA JW-480 CTRP2 0.0020 66.0000
SIMA JW-7-24-1 GDSC1 0.0400 10.2400
SIMA JW-7-52-1 GDSC1 0.0047 1.2000
SIMA kb NB 142-70 GDSC1 0.0781 20.0000
SIMA KIN001-042 GDSC1 0.0400 10.2400
SIMA KIN001-236 GDSC1 0.0400 10.2400
SIMA KIN001-244 GDSC1 0.0781 20.0000
SIMA KIN001-260 GDSC1 0.0781 20.0000
SIMA KIN001-266 GDSC1 0.0781 20.0000
SIMA KIN001-270 GDSC1 0.0781 20.0000
SIMA Kobe2602 GDSC1 0.0781 20.0000
SIMA KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
SIMA KU 0060648 CTRP2 0.0010 33.0000
SIMA KU-55933 GDSC1,CTRP2 0.0020 66.0000
SIMA KU-60019 GDSC1,CTRP2 0.0020 66.0000
SIMA KX2-391 CTRP2 0.0020 66.0000
SIMA L-685458 CCLE 0.0025 8.0000
SIMA L-Oxonoreleagnine GDSC2 0.0030 3.0000
SIMA Lapatinib GDSC1,GDSC2,CCLE 0.0025 10.0000
SIMA LBH-589 CTRP2 0.0020 66.0000
SIMA LBW242 CCLE 0.0025 8.0000
SIMA LCL161 GDSC1,GDSC2 0.0100 10.0000
SIMA LDN-193189 GDSC1 0.0400 10.2400
SIMA Leflunomide GDSC2 0.1001 100.0000
SIMA Lenalidomide GDSC1,GDSC2 0.0100 10.0000
SIMA leptomycin B CTRP2 0.0020 66.0000
SIMA Lestaurtinib GDSC1,GDSC2 0.0020 2.0000
SIMA LFM-A13 GDSC1 0.0625 16.0000
SIMA LGK974 GDSC1,GDSC2 0.0050 10.0000
SIMA LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
SIMA Linifanib GDSC1,CTRP2 0.0020 66.0000
SIMA Linsitinib GDSC1,GDSC2 0.0025 10.0000
SIMA LJI308 GDSC2 0.0100 10.0000
SIMA LMB_AB1 GDSC2 0.0100 10.0000
SIMA LMB_AB2 GDSC2 0.0100 10.0000
SIMA LMB_AB3 GDSC2 0.0100 10.0000
SIMA LMP744 GDSC2 0.0030 3.0000
SIMA Luminespib GDSC1,GDSC2 0.0003 1.0000
SIMA LY2109761 GDSC2 0.0100 10.0000
SIMA Masitinib GDSC1 0.0781 20.0000
SIMA MCT1_6447 GDSC1 0.0391 10.0000
SIMA MCT4_1422 GDSC1 0.0391 10.0000
SIMA Mdivi-1 CTRP2 0.0020 66.0000
SIMA MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
SIMA Methotrexate GDSC1,CTRP2 0.0008 66.0000
SIMA MG-132 GDSC1,GDSC2 0.0039 4.0000
SIMA Midostaurin GDSC1 0.0020 0.5120
SIMA MIM1 GDSC1,GDSC2 0.0100 40.0000
SIMA MIRA-1 GDSC2 0.0100 10.0000
SIMA Mirin GDSC1,GDSC2 0.1001 100.0000
SIMA mitomycin CTRP2 0.0015 50.0000
SIMA Mitomycin-C GDSC1 0.0625 16.0000
SIMA Mitoxantrone GDSC2 0.0030 3.0000
SIMA MK-0752 CTRP2 0.0020 66.0000
SIMA MK-1775 GDSC2 0.0100 10.0000
SIMA MK-2206 GDSC1,GDSC2 0.0100 10.0000
SIMA MK-8776 GDSC2 0.0050 5.0000
SIMA ML006 CTRP2 0.0160 530.0000
SIMA ML162 CTRP2 0.0010 33.0000
SIMA ML323 GDSC2 0.0200 20.0000
SIMA MN-64 GDSC2 0.0100 10.0000
SIMA Motesanib GDSC1,GDSC2 0.0078 10.0000
SIMA MPS-1-IN-1 GDSC1 0.0781 20.0000
SIMA Mycophenolic acid GDSC2 0.0100 10.0000
SIMA myriocin CTRP2 0.0010 33.0000
SIMA N-acetyl cysteine GDSC2 2.0011 2000.0000
SIMA N22899-6-C1 GDSC1 0.0391 10.0000
SIMA N23918-95-7 GDSC1 0.0391 10.0000
SIMA N24798-49-A1 GDSC1 0.0391 10.0000
SIMA N25720-51-A1 GDSC2 0.0100 10.0000
SIMA N27922-53-1 GDSC2 0.0100 10.0000
SIMA N29087-69-1 GDSC2 0.0100 10.0000
SIMA N30652-18-1 GDSC2 0.0100 10.0000
SIMA nakiterpiosin CTRP2 0.0010 33.0000
SIMA narciclasine CTRP2 0.0010 33.0000
SIMA Navitoclax GDSC1,GDSC2 0.0020 10.0000
SIMA navitoclax:gemcitabine (1:1 mol-mol) CTRP2 0.0010 33.0000
SIMA navitoclax:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
SIMA navitoclax:pluripotin (1:1 mol-mol) CTRP2 0.0010 33.0000
SIMA navitoclax:sorafenib (1:1 mol-mol) CTRP2 0.0015 50.0000
SIMA Nelarabine GDSC2 0.0200 20.0000
SIMA NG-25 GDSC1 0.0400 10.2400
SIMA niclosamide CTRP2 0.0010 33.0000
SIMA Nilotinib GDSC1,GDSC2,CTRP2,CCLE 0.0020 66.0000
SIMA Niraparib GDSC2 0.0100 10.0000
SIMA NPK76-II-72-1 GDSC1 0.0400 10.2400
SIMA NSC-207895 GDSC1 0.0781 20.0000
SIMA NSC-87877 GDSC1 0.0625 16.0000
SIMA NSC30930 CTRP2 0.0020 66.0000
SIMA NSC319726 GDSC1 0.0010 0.2560
SIMA NSC632839 CTRP2 0.0160 33.0000
SIMA NU7441 GDSC1,GDSC2 0.0078 10.0000
SIMA Nutlin-3a GDSC1,GDSC2,CTRP2,CCLE 0.0025 150.0000
SIMA NVP-ADW742 GDSC2 0.0100 10.0000
SIMA NVP-BHG712 GDSC1 0.0400 10.2400
SIMA NVP-TAE684 GDSC1,CCLE 0.0025 8.0000
SIMA Obatoclax Mesylate GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA OF-1 GDSC2 0.0100 10.0000
SIMA Olaparib GDSC1,GDSC2 0.0100 10.0000
SIMA oligomycin A CTRP2 0.0010 33.0000
SIMA Omipalisib GDSC1 0.0005 0.1280
SIMA OSI-027 GDSC1,GDSC2 0.0040 20.0000
SIMA OSI-930 GDSC1,CTRP2 0.0020 66.0000
SIMA Osimertinib GDSC2 0.0010 1.0000
SIMA OSU-03012 GDSC1 0.0625 16.0000
SIMA OTX015 GDSC2 0.0100 10.0000
SIMA ouabain CTRP2 0.0081 270.0000
SIMA Oxaliplatin GDSC2,CTRP2 0.0100 66.0000
SIMA P22077 GDSC2 0.0100 10.0000
SIMA PAC-1 GDSC1 0.0100 2.5600
SIMA Paclitaxel GDSC1,GDSC2,CTRP2,CCLE 0.0000 66.0000
SIMA PAK_5339 GDSC2 0.0300 30.0000
SIMA Palbociclib GDSC1,GDSC2,CCLE 0.0025 10.0000
SIMA Panobinostat GDSC1,CCLE 0.0025 8.0000
SIMA parbendazole CTRP2 0.0020 66.0000
SIMA PARP_0108 GDSC1 0.0098 2.5000
SIMA PARP_9482 GDSC1 0.0098 2.5000
SIMA PARP_9495 GDSC1 0.0098 2.5000
SIMA Parthenolide GDSC1 0.0195 5.0000
SIMA Pazopanib GDSC1,CTRP2 0.0020 66.0000
SIMA PBD-288 GDSC2 0.0050 5.0000
SIMA PCI-34051 GDSC2 0.0100 10.0000
SIMA PD0325901 GDSC1,GDSC2,CCLE 0.0003 8.0000
SIMA PD173074 GDSC1,GDSC2 0.0020 10.0000
SIMA PD318088 CTRP2 0.0020 66.0000
SIMA Pelitinib GDSC1 0.0098 2.5000
SIMA Pemetrexed GDSC1 0.0100 2.5600
SIMA Pevonedistat GDSC1,GDSC2 0.0039 10.0000
SIMA PF-00299804 GDSC1 0.0781 20.0000
SIMA PF-4708671 GDSC1 0.0391 10.0000
SIMA PF-562271 GDSC1 0.0100 2.5600
SIMA PFI-1 GDSC1 0.0391 10.0000
SIMA PFI3 GDSC1,GDSC2 0.0100 10.0000
SIMA PHA-665752 GDSC1,CCLE 0.0025 8.0000
SIMA PHA-793887 GDSC1 0.0400 10.2400
SIMA Phenformin GDSC1 15.6250 4000.0000
SIMA PI-103 GDSC1 0.0400 10.2400
SIMA PI3Ka_4409 GDSC1 0.0391 10.0000
SIMA Picolinici-acid GDSC2 0.0100 10.0000
SIMA Pictilisib GDSC1,GDSC2,CTRP2 0.0020 66.0000
SIMA pifithrin-alpha CTRP2 0.0071 230.0000
SIMA PIK-93 GDSC1,CTRP2 0.0020 66.0000
SIMA Pilaralisib GDSC1 0.0781 20.0000
SIMA Piperlongumine GDSC1 0.0391 10.0000
SIMA piperlongumine:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
SIMA PL-DI CTRP2 0.0020 66.0000
SIMA PLK_6522 GDSC1 0.0024 0.6250
SIMA pluripotin CTRP2 0.0010 33.0000
SIMA PLX-4720 GDSC1,GDSC2,CCLE 0.0025 10.0000
SIMA Podophyllotoxin bromide GDSC2 0.0010 1.0000
SIMA POMHEX GDSC2 0.0100 10.0000
SIMA Ponatinib GDSC1 0.0020 0.5120
SIMA PRIMA-1MET GDSC2 0.0300 30.0000
SIMA prochlorperazine CTRP2 0.0020 66.0000
SIMA PRT062607 GDSC2 0.0100 10.0000
SIMA PX-12 CTRP2 0.0030 100.0000
SIMA Pyridostatin GDSC2 0.0100 10.0000
SIMA Pyrimethamine GDSC1 0.0781 20.0000
SIMA QL-VIII-58 GDSC1 0.0391 10.0000
SIMA QL-X-138 GDSC1 0.0400 10.2400
SIMA QL-XI-92 GDSC1 0.0400 10.2400
SIMA QL-XII-47 GDSC1 0.0400 10.2400
SIMA QL-XII-61 GDSC1 0.0391 10.0000
SIMA QS11 GDSC1 0.0400 10.2400
SIMA Quizartinib GDSC1 0.0040 1.0240
SIMA RAF_9304 GDSC1 0.0391 10.0000
SIMA RAF265 CCLE 0.0025 8.0000
SIMA Rapamycin GDSC1,GDSC2 0.0000 0.1000
SIMA Refametinib GDSC1,GDSC2 0.0100 10.0000
SIMA Regorafenib CTRP2 0.0320 66.0000
SIMA Remodelin GDSC2 0.0500 50.0000
SIMA RG-108 CTRP2 0.0081 270.0000
SIMA Ribociclib GDSC2 0.0020 2.0000
SIMA rigosertib CTRP2 0.0020 66.0000
SIMA RO-3306 GDSC1 0.0195 5.0000
SIMA Romidepsin GDSC2 0.0000 0.0100
SIMA rTRAIL GDSC1 0.0004 0.1000
SIMA RU-SKI 43 GDSC1 0.0781 20.0000
SIMA Rucaparib GDSC1,GDSC2 0.0050 5.0000
SIMA Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
SIMA RVX-208 GDSC2 0.0100 10.0000
SIMA S-Trityl-L-cysteine GDSC1 0.0200 5.1200
SIMA Sabutoclax GDSC2 0.0100 10.0000
SIMA Salubrinal GDSC1 0.0625 16.0000
SIMA Sapitinib GDSC2 0.0050 10.0000
SIMA Saracatinib GDSC1,CTRP2,CCLE 0.0020 66.0000
SIMA Savolitinib GDSC2 0.0010 1.0000
SIMA SB-431542 CTRP2 0.0020 66.0000
SIMA SB-525334 CTRP2 0.0020 66.0000
SIMA SB-743921 CTRP2 0.0010 33.0000
SIMA SB505124 GDSC1 0.0391 20.0000
SIMA SB52334 GDSC1 0.0781 20.0000
SIMA SB590885 GDSC1,GDSC2 0.0050 5.0000
SIMA SCH-79797 CTRP2 0.0011 37.0000
SIMA SCH772984 GDSC2 0.0050 5.0000
SIMA Schweinfurthin A GDSC2 0.0010 1.0000
SIMA Seliciclib GDSC1 0.0625 16.0000
SIMA Selisistat GDSC1,CTRP2 0.0024 80.0000
SIMA Selumetinib GDSC1,GDSC2,CTRP2,CCLE 0.0025 270.0000
SIMA selumetinib:decitabine (4:1 mol-mol) CTRP2 0.0051 170.0000
SIMA selumetinib:GDC-0941 (4:1 mol-mol) CTRP2 0.0051 170.0000
SIMA selumetinib:JQ-1 (4:1 mol-mol) CTRP2 0.0051 170.0000
SIMA selumetinib:navitoclax (8:1 mol-mol) CTRP2 0.0046 150.0000
SIMA selumetinib:piperlongumine (8:1 mol-mol) CTRP2 0.0046 150.0000
SIMA selumetinib:PLX-4032 (8:1 mol-mol) CTRP2 0.0046 150.0000
SIMA selumetinib:vorinostat (8:1 mol-mol) CTRP2 0.0046 150.0000
SIMA semagacestat CTRP2 0.0020 66.0000
SIMA Sepantronium bromide GDSC1,GDSC2 0.0100 10.0000
SIMA Serdemetan GDSC1,GDSC2 0.0100 10.0000
SIMA SGC-CBP30 GDSC2 0.0050 5.0000
SIMA SGC0946 GDSC1 0.0020 0.5000
SIMA Shikonin GDSC1 0.0625 16.0000
SIMA Sinularin GDSC2 0.0030 3.0000
SIMA SL0101 GDSC1 0.0391 10.0000
SIMA SMER-3 CTRP2 0.0020 66.0000
SIMA SN-38 GDSC1,GDSC2,CTRP2 0.0000 1.3000
SIMA SNX-2112 GDSC1,CTRP2 0.0010 33.0000
SIMA SNX-2112:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
SIMA Sorafenib GDSC1,GDSC2,CCLE 0.0025 10.0000
SIMA Sphingosine Kinase 1 Inhibitor II GDSC1,CTRP2 0.0010 33.0000
SIMA SR-II-138A CTRP2 0.0010 33.0000
SIMA SR1001 CTRP2 0.0020 66.0000
SIMA Staurosporine GDSC2 0.0078 2.0000
SIMA StemRegenin 1 CTRP2 0.0020 66.0000
SIMA STF-31 CTRP2 0.0020 66.0000
SIMA STF-62247 GDSC1 0.0400 10.2400
SIMA SU11274 GDSC1 0.0400 10.2400
SIMA Sunitinib GDSC1 0.0312 8.0000
SIMA T0901317 GDSC1 0.0400 10.2400
SIMA TAF1_5496 GDSC2 0.0100 10.0000
SIMA TAK-715 GDSC1 0.0781 20.0000
SIMA Talazoparib GDSC1,GDSC2 0.0100 10.0000
SIMA Tamoxifen GDSC1,GDSC2 0.0100 10.0000
SIMA Tanespimycin GDSC1,GDSC2,CCLE 0.0010 8.0000
SIMA tanespimycin:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
SIMA tanespimycin:gemcitabine (1:1 mol-mol) CTRP2 0.0010 33.0000
SIMA TANK_1366 GDSC1 0.0098 2.5000
SIMA Taselisib GDSC2 0.0040 10.0000
SIMA Telomerase Inhibitor IX GDSC2 0.0100 10.0000
SIMA Temozolomide GDSC1,GDSC2 0.0300 30.0000
SIMA Temsirolimus GDSC1,GDSC2 0.0008 1.0000
SIMA Teniposide GDSC2,CTRP2 0.0010 33.0000
SIMA Tenovin-6 GDSC1 0.0781 20.0000
SIMA TGX221 GDSC1,CTRP2 0.0020 66.0000
SIMA Thapsigargin GDSC1 0.0020 0.5120
SIMA THR-101 GDSC2 0.0100 10.0000
SIMA THR-102 GDSC2 0.0100 10.0000
SIMA THR-103 GDSC2 0.0100 10.0000
SIMA THZ-2-102-1 GDSC1 0.0098 2.5000
SIMA THZ-2-49 GDSC1 0.0781 20.0000
SIMA Tipifarnib GDSC1 0.0625 16.0000
SIMA tipifarnib-P2 CTRP2 0.0010 33.0000
SIMA Tivozanib GDSC1 0.0005 0.1280
SIMA TKI258 CCLE 0.0025 8.0000
SIMA TL-1-85 GDSC1 0.0400 10.2400
SIMA TL-2-105 GDSC1 0.0400 10.2400
SIMA Topotecan GDSC2,CTRP2,CCLE 0.0020 66.0000
SIMA Torin 2 GDSC1 0.0781 20.0000
SIMA Tozasertib GDSC1 0.0078 2.0000
SIMA TPCA-1 GDSC1,CTRP2 0.0020 66.0000
SIMA Trametinib GDSC1,GDSC2 0.0010 1.0000
SIMA Tretinoin GDSC1,CTRP2 0.0041 130.0000
SIMA tretinoin:navitoclax (4:1 mol-mol) CTRP2 0.0025 83.0000
SIMA Trichostatin A GDSC1 0.0040 1.0240
SIMA TTK_3146 GDSC1 0.0391 10.0000
SIMA Tubastatin A GDSC1 0.0781 20.0000
SIMA TW 37 GDSC1 0.0195 5.0000
SIMA TWS119 GDSC1 0.0781 20.0000
SIMA Ulixertinib GDSC2 0.0020 10.0000
SIMA ULK1_4989 GDSC2 0.0300 30.0000
SIMA UMI-77 GDSC2 0.0100 10.0000
SIMA UNC0379 GDSC2 0.0100 10.0000
SIMA UNC0638 GDSC1,GDSC2 0.0050 40.0000
SIMA UNC0642 GDSC1 0.0020 0.5000
SIMA UNC1215 GDSC1 0.0039 1.0000
SIMA Uprosertib GDSC2 0.0100 10.0000
SIMA VE-822 GDSC2 0.0050 5.0000
SIMA VE821 GDSC2 0.0100 10.0000
SIMA Veliparib GDSC1,GDSC2,CTRP2 0.0010 33.0000
SIMA Venetoclax GDSC2 0.0010 1.0000
SIMA Venotoclax GDSC1 0.0010 0.2560
SIMA Vinblastine GDSC1,GDSC2 0.0001 0.1000
SIMA Vincristine GDSC2,CTRP2 0.0030 130.0000
SIMA Vinorelbine GDSC1,GDSC2 0.0001 0.1000
SIMA Vismodegib GDSC1,GDSC2 0.0100 10.0000
SIMA VNLG-124 GDSC1 0.0200 5.1200
SIMA Vorinostat GDSC1,GDSC2,CTRP2 0.0010 33.0000
SIMA vorinostat:carboplatin (1:1 mol-mol) CTRP2 0.0320 66.0000
SIMA vorinostat:navitoclax (4:1 mol-mol) CTRP2 0.0010 33.0000
SIMA Voxtalisib GDSC1 0.0781 20.0000
SIMA VSP34_8731 GDSC2 0.0300 30.0000
SIMA VTP-A GDSC2 0.0010 1.0000
SIMA VTP-B GDSC2 0.0010 1.0000
SIMA VX-11e GDSC1,GDSC2 0.0100 10.0000
SIMA VX-702 GDSC1 0.0078 2.0000
SIMA WAY-362450 CTRP2 0.0020 66.0000
SIMA Wee1 Inhibitor GDSC1,GDSC2 0.0078 10.0000
SIMA WEHI-539 GDSC2 0.0100 10.0000
SIMA WH-4-023 GDSC1 0.0200 5.1200
SIMA WHI-P97 GDSC1 0.0400 10.2400
SIMA WIKI4 GDSC2 0.0100 10.0000
SIMA Wnt-C59 GDSC1,GDSC2 0.0100 10.0000
SIMA WYE-125132 GDSC1 0.0400 10.2400
SIMA WZ-1-84 GDSC1 0.0400 10.2400
SIMA WZ3105 GDSC1 0.0050 1.2800
SIMA WZ4003 GDSC2 0.0100 10.0000
SIMA WZ8040 CTRP2 0.0020 66.0000
SIMA XAV939 GDSC1,GDSC2 0.0100 10.0000
SIMA XMD11-85h GDSC1 0.0391 10.0000
SIMA XMD13-2 GDSC1 0.0400 10.2400
SIMA XMD14-99 GDSC1 0.0400 10.2400
SIMA XMD15-27 GDSC1 0.0400 10.2400
SIMA XMD8-85 GDSC1 0.0312 8.0000
SIMA XMD8-92 GDSC1 0.0391 10.0000
SIMA Y-39983 GDSC1 0.0781 20.0000
SIMA YK-4-279 GDSC1,GDSC2,CTRP2 0.0010 33.0000
SIMA YM201636 GDSC1 0.0200 5.1200
SIMA Z-LLNle-CHO GDSC1 0.0100 2.5600
SIMA ZD-6474 CCLE 0.0025 8.0000
SIMA ZG-10 GDSC1 0.0391 10.0000
SIMA Zibotentan GDSC1 0.0781 20.0000
SIMA ZL049 GDSC1 0.0391 10.0000
SIMA ZL109 GDSC1 0.0391 10.0000
SIMA ZM447439 GDSC1,GDSC2 0.0100 10.0000
SIMA Zoledronate GDSC2 0.0020 2.0000
SIMA ZSTK474 GDSC1,CTRP2 0.0020 66.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC