Drug : Fsc231

CTRP2 Name : FSC231

Dataset : All
Synonyms :
Targets : PICK1
Pathways : inhibitor of PDZ domain of protein interacting with PRKCA 1 (PICK1)

Information Cards

Click to show/hide information cards below or download all drug response information.

           
     

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including drug name, cell line name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Drug name Cellosaurus ID Original Dataset(s) Min Dose Max Dose Dose-response
FSC231 CAS-1 CTRP2 0.0081 270.0000
FSC231 KPL-1 CTRP2 0.0081 270.0000
FSC231 MKN1 CTRP2 0.0081 270.0000
FSC231 253J-BV CTRP2 0.0081 270.0000
FSC231 BFTC-905 CTRP2 0.0081 270.0000
FSC231 BFTC-909 CTRP2 0.0081 270.0000
FSC231 CADO-ES1 CTRP2 0.0081 270.0000
FSC231 CAL-120 CTRP2 0.0081 270.0000
FSC231 CAL-29 CTRP2 0.0081 270.0000
FSC231 CAL-62 CTRP2 0.0081 270.0000
FSC231 HUCC-T1 CTRP2 0.0081 270.0000
FSC231 NMC-G1 CTRP2 0.0081 270.0000
FSC231 RPMI-7951 CTRP2 0.0081 270.0000
FSC231 253J CTRP2 0.0081 270.0000
FSC231 ALL-SIL CTRP2 0.0081 270.0000
FSC231 SIMA CTRP2 0.0081 270.0000
FSC231 SNU-489 CTRP2 0.0081 270.0000
FSC231 SNU-626 CTRP2 0.0081 270.0000
FSC231 SNU-738 CTRP2 0.0081 270.0000
FSC231 SNU-878 CTRP2 0.0081 270.0000
FSC231 TUHR4TKB CTRP2 0.0081 270.0000
FSC231 ACC-MESO-1 CTRP2 0.0081 270.0000
FSC231 B-CPAP CTRP2 0.0081 270.0000
FSC231 CGTH-W-1 CTRP2 0.0081 270.0000
FSC231 COLO680N CTRP2 0.0081 270.0000
FSC231 ECC12 CTRP2 0.0081 270.0000
FSC231 HCC95 CTRP2 0.0081 270.0000
FSC231 JMSU-1 CTRP2 0.0081 270.0000
FSC231 RH41 CTRP2 0.0081 270.0000
FSC231 SNU-175 CTRP2 0.0081 270.0000
FSC231 WSU-DLCL2 CTRP2 0.0081 270.0000
FSC231 23132-87 CTRP2 0.0081 270.0000
FSC231 8305C CTRP2 0.0081 270.0000
FSC231 BHY CTRP2 0.0081 270.0000
FSC231 GSU CTRP2 0.0081 270.0000
FSC231 JIMT-1 CTRP2 0.0081 270.0000
FSC231 KMRC-20 CTRP2 0.0081 270.0000
FSC231 OUMS-23 CTRP2 0.0081 270.0000
FSC231 SNU-1076 CTRP2 0.0081 270.0000
FSC231 SNU-1196 CTRP2 0.0081 270.0000
FSC231 SNU-8 CTRP2 0.0081 270.0000
FSC231 A-375 CTRP2 0.0081 270.0000
FSC231 A-549 CTRP2 0.0081 270.0000
FSC231 NCI-H2009 CTRP2 0.0081 270.0000
FSC231 SNU-201 CTRP2 0.0081 270.0000
FSC231 SUIT-2 CTRP2 0.0081 270.0000
FSC231 SNU-1079 CTRP2 0.0081 270.0000
FSC231 COLO741 CTRP2 0.0081 270.0000
FSC231 DEL CTRP2 0.0081 270.0000
FSC231 HARA[HUMANSQUAMOUSCELLLUNGCARCINOMA] CTRP2 0.0081 270.0000
FSC231 HCC15 CTRP2 0.0081 270.0000
FSC231 KP-4 CTRP2 0.0081 270.0000
FSC231 LU-99 CTRP2 0.0081 270.0000
FSC231 NCI-H1155 CTRP2 0.0081 270.0000
FSC231 NCI-H1581 CTRP2 0.0081 270.0000
FSC231 NCI-H2106 CTRP2 0.0081 270.0000
FSC231 NCI-H358 CTRP2 0.0081 270.0000
FSC231 DLD-1 CTRP2 0.0081 270.0000
FSC231 EM-2 CTRP2 0.0081 270.0000
FSC231 JURL-MK1 CTRP2 0.0081 270.0000
FSC231 P12-ICHIKAWA CTRP2 0.0081 270.0000
FSC231 KE-37 CTRP2 0.0081 270.0000
FSC231 KMS-21-BM CTRP2 0.0081 270.0000
FSC231 LI-7 CTRP2 0.0081 270.0000
FSC231 MOLM-13 CTRP2 0.0081 270.0000
FSC231 NCI-H28 CTRP2 0.0081 270.0000
FSC231 639V CTRP2 0.0081 270.0000
FSC231 BXPC-3 CTRP2 0.0081 130.0000
FSC231 CML-T1 CTRP2 0.0081 270.0000
FSC231 GSS CTRP2 0.0081 130.0000
FSC231 HCC366 CTRP2 0.0081 270.0000
FSC231 KURAMOCHI CTRP2 0.0081 270.0000
FSC231 LS411N CTRP2 0.0081 270.0000
FSC231 LS513 CTRP2 0.0081 270.0000
FSC231 ONCO-DG-1 CTRP2 0.0081 130.0000
FSC231 ONS-76 CTRP2 0.0081 270.0000
FSC231 SK-CO-1 CTRP2 0.0081 270.0000
FSC231 SW48 CTRP2 0.0081 270.0000
FSC231 VM-CUB-1 CTRP2 0.0081 130.0000
FSC231 BEN CTRP2 0.0081 270.0000
FSC231 CFPAC-1 CTRP2 0.0081 270.0000
FSC231 HCC78 CTRP2 0.0081 270.0000
FSC231 HT CTRP2 0.0081 270.0000
FSC231 KU-19-19 CTRP2 0.0081 270.0000
FSC231 NCI-H1299 CTRP2 0.0081 270.0000
FSC231 NCI-H727 CTRP2 0.0081 270.0000
FSC231 NCO2 CTRP2 0.0081 270.0000
FSC231 OVTOKO CTRP2 0.0081 270.0000
FSC231 P31-FUJ CTRP2 0.0081 270.0000
FSC231 PEER CTRP2 0.0081 270.0000
FSC231 RPMI-8402 CTRP2 0.0081 270.0000
FSC231 SHP-77 CTRP2 0.0081 270.0000
FSC231 SNU-1077 CTRP2 0.0081 270.0000
FSC231 SNU-620 CTRP2 0.0081 270.0000
FSC231 SU-DHL-1 CTRP2 0.0081 270.0000
FSC231 COLO205 CTRP2 0.0081 270.0000
FSC231 EHEB CTRP2 0.0081 270.0000
FSC231 KI-JK CTRP2 0.0081 270.0000
FSC231 KMM-1 CTRP2 0.0081 270.0000
FSC231 LCLC-103H CTRP2 0.0081 270.0000
FSC231 MKN45 CTRP2 0.0081 270.0000
FSC231 NCI-H2405 CTRP2 0.0081 270.0000
FSC231 NCI-H650 CTRP2 0.0081 270.0000
FSC231 OS-RC-2 CTRP2 0.0081 270.0000
FSC231 OVSAHO CTRP2 0.0081 270.0000
FSC231 QGP-1 CTRP2 0.0081 270.0000
FSC231 RL95-2 CTRP2 0.0081 270.0000
FSC231 SNU-1041 CTRP2 0.0081 270.0000
FSC231 SNU-1066 CTRP2 0.0081 270.0000
FSC231 SW1353 CTRP2 0.0081 270.0000
FSC231 SNU-213 CTRP2 0.0081 270.0000
FSC231 8505C CTRP2 0.0081 270.0000
FSC231 CALU-3 CTRP2 0.0081 270.0000
FSC231 DAOY CTRP2 0.0081 270.0000
FSC231 GB-1 CTRP2 0.0081 270.0000
FSC231 HCC1171 CTRP2 0.0081 270.0000
FSC231 HCC44 CTRP2 0.0081 270.0000
FSC231 NCI-H211 CTRP2 0.0081 270.0000
FSC231 RERF-LC-A1 CTRP2 0.0081 270.0000
FSC231 SBC-5 CTRP2 0.0081 270.0000
FSC231 SF126 CTRP2 0.0081 270.0000
FSC231 SNU-119 CTRP2 0.0081 270.0000
FSC231 SNU-182 CTRP2 0.0081 270.0000
FSC231 TCCSUP CTRP2 0.0081 270.0000
FSC231 CAMA-1 CTRP2 0.0081 270.0000
FSC231 DETROIT562 CTRP2 0.0081 270.0000
FSC231 HEC-1-B CTRP2 0.0081 270.0000
FSC231 HEP3B2.1-7 CTRP2 0.0081 270.0000
FSC231 HSC-3 CTRP2 0.0081 270.0000
FSC231 MCF-7 CTRP2 0.0081 270.0000
FSC231 SNU-1105 CTRP2 0.0081 270.0000
FSC231 U-87MGATCC CTRP2 0.0081 270.0000
FSC231 22RV1 CTRP2 0.0081 270.0000
FSC231 769-P CTRP2 0.0081 270.0000
FSC231 COLO699 CTRP2 0.0081 270.0000
FSC231 DOV13 CTRP2 0.0081 270.0000
FSC231 ES2 CTRP2 0.0081 270.0000
FSC231 HCC1806 CTRP2 0.0081 270.0000
FSC231 HCC1954 CTRP2 0.0081 270.0000
FSC231 HPAF-II CTRP2 0.0081 270.0000
FSC231 KHM-1B CTRP2 0.0081 270.0000
FSC231 OVISE CTRP2 0.0081 270.0000
FSC231 JVM-3 CTRP2 0.0081 270.0000
FSC231 SNU-C2A CTRP2 0.0081 270.0000
FSC231 5637 CTRP2 0.0081 270.0000
FSC231 CAL-12T CTRP2 0.0081 270.0000
FSC231 HCC1588 CTRP2 0.0081 270.0000
FSC231 HCC1833 CTRP2 0.0081 270.0000
FSC231 HCC2279 CTRP2 0.0081 270.0000
FSC231 KE-97 CTRP2 0.0081 270.0000
FSC231 KP-3 CTRP2 0.0081 270.0000
FSC231 KU812 CTRP2 0.0081 270.0000
FSC231 KYSE-140 CTRP2 0.0081 270.0000
FSC231 NALM-6 CTRP2 0.0081 270.0000
FSC231 NUGC-4 CTRP2 0.0081 270.0000
FSC231 TT CTRP2 0.0081 270.0000
FSC231 AGS CTRP2 0.0081 270.0000
FSC231 HCT116 CTRP2 0.0081 270.0000
FSC231 HEC-108 CTRP2 0.0081 270.0000
FSC231 HEC-59 CTRP2 0.0081 270.0000
FSC231 HMC-1-8 CTRP2 0.0081 270.0000
FSC231 HT-29 CTRP2 0.0081 270.0000
FSC231 ISHIKAWA(HERAKLIO)02ER- CTRP2 0.0081 270.0000
FSC231 JHOC-5 CTRP2 0.0081 270.0000
FSC231 KYSE-180 CTRP2 0.0081 270.0000
FSC231 LS180 CTRP2 0.0081 270.0000
FSC231 MELHO CTRP2 0.0081 270.0000
FSC231 MHH-ES-1 CTRP2 0.0081 270.0000
FSC231 MOR-CPR CTRP2 0.0081 270.0000
FSC231 NCI-H460 CTRP2 0.0081 270.0000
FSC231 HCC2108 CTRP2 0.0081 270.0000
FSC231 HCC827 CTRP2 0.0081 270.0000
FSC231 HEC-251 CTRP2 0.0081 270.0000
FSC231 HEC-265 CTRP2 0.0081 270.0000
FSC231 HEC-6 CTRP2 0.0081 270.0000
FSC231 HEL CTRP2 0.0081 270.0000
FSC231 JHUEM-2 CTRP2 0.0081 270.0000
FSC231 JURKAT CTRP2 0.0081 270.0000
FSC231 KCL-22 CTRP2 0.0081 270.0000
FSC231 KE-39 CTRP2 0.0081 270.0000
FSC231 KM-H2 CTRP2 0.0081 270.0000
FSC231 LAMA-84 CTRP2 0.0081 270.0000
FSC231 NCI-H2030 CTRP2 0.0081 270.0000
FSC231 SNU-719 CTRP2 0.0081 270.0000
FSC231 HCC1569 CTRP2 0.0081 270.0000
FSC231 KLE CTRP2 0.0081 270.0000
FSC231 KMS-26 CTRP2 0.0081 270.0000
FSC231 KMS-27 CTRP2 0.0081 270.0000
FSC231 NCI-H1838 CTRP2 0.0081 270.0000
FSC231 NCI-H196 CTRP2 0.0081 270.0000
FSC231 NCI-H292 CTRP2 0.0081 270.0000
FSC231 SK-MEL-1 CTRP2 0.0081 270.0000
FSC231 HCC1937 CTRP2 0.0081 270.0000
FSC231 HDLM-2 CTRP2 0.0081 270.0000
FSC231 HUH-28 CTRP2 0.0081 270.0000
FSC231 MV4-11 CTRP2 0.0081 270.0000
FSC231 NCI-H526 CTRP2 0.0081 270.0000
FSC231 NCI-H69 CTRP2 0.0081 270.0000
FSC231 NCI-H929 CTRP2 0.0081 270.0000
FSC231 NCI-N87 CTRP2 0.0081 270.0000
FSC231 PF-382 CTRP2 0.0081 270.0000
FSC231 SF295 CTRP2 0.0081 270.0000
FSC231 SNU-1272 CTRP2 0.0081 270.0000
FSC231 SNU-308 CTRP2 0.0081 270.0000
FSC231 SNU-478 CTRP2 0.0081 270.0000
FSC231 BHT-101 CTRP2 0.0081 270.0000
FSC231 CAL-148 CTRP2 0.0081 270.0000
FSC231 CAL-51 CTRP2 0.0081 270.0000
FSC231 HCC1395 CTRP2 0.0081 270.0000
FSC231 HT115 CTRP2 0.0081 270.0000
FSC231 LN-18 CTRP2 0.0081 270.0000
FSC231 LN-229 CTRP2 0.0081 270.0000
FSC231 NCI-H1734 CTRP2 0.0081 270.0000
FSC231 NCI-H2291 CTRP2 0.0081 270.0000
FSC231 RERF-LC-AD1 CTRP2 0.0081 270.0000
FSC231 SNU-1214 CTRP2 0.0081 270.0000
FSC231 SNU-46 CTRP2 0.0081 270.0000
FSC231 SNU-466 CTRP2 0.0081 270.0000
FSC231 SNU-5 CTRP2 0.0081 270.0000
FSC231 SNU-668 CTRP2 0.0081 270.0000
FSC231 SNU-899 CTRP2 0.0081 270.0000
FSC231 TE-10 CTRP2 0.0081 270.0000
FSC231 TE-9 CTRP2 0.0081 270.0000
FSC231 YD-10B CTRP2 0.0081 270.0000
FSC231 YD-15 CTRP2 0.0081 270.0000
FSC231 YD-38 CTRP2 0.0081 270.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Cell lines with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Cell lines with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Cell lines with highest and lowest AUC

Associated Genes (Mutation)

Genes with the largest and lowest Racksum’s effect sizes, calculated by comparing IC50 between the mutant and wide type cell lines using cell lines from pancan data.

Associated Genes (Gene Expression)

Genes with the highest and lowest Spearman correlations, calculated by comparing gene expression and IC50 across cell lines from pancan data.