Cell Line : M059J
Cellosaurus Index : CVCL_0400
Cellosaurus ID : M059J
GDSC1 Name
, GDSC2 Name
: M059J
CCLE Name
: M059J_CENTRAL_NERVOUS_SYSTEM
Cancer Type : central_nervous_system
Dataset : All
Drug Response Information
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Cellosaurus ID | Drug Name | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| M059J | (5Z)-7-Oxozeaenol | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | 123138 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | 123829 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 150412 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 5-azacytidine | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | 5-Fluorouracil | GDSC1,GDSC2 | 0.0200 | 32.0000 |
|
| M059J | 50869 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 615590 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 630600 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 667880 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 720427 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 729189 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 741909 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | 743380 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | 765771 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | 776928 | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | A-366 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | A-83-01 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | ABT737 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Acetalax | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | ACY-1215 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | AEW541 | CCLE | 0.0025 | 8.0000 |
|
| M059J | Afatinib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| M059J | Afuresertib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AGI-5198 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AGI-6780 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| M059J | AGK-2 | GDSC2 | 0.0040 | 4.0000 |
|
| M059J | AICA Ribonucleotide | GDSC1 | 7.8125 | 2000.0000 |
|
| M059J | AKT inhibitor VIII | GDSC1 | 0.0100 | 10.2400 |
|
| M059J | Alectinib | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | Alisertib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| M059J | Alpelisib | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | alpha-lipoic acid | GDSC2 | 0.1211 | 121.0000 |
|
| M059J | AMG-319 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Amuvatinib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Apitolisib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | AR-42 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | Ara-G | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | ARRY-520 | GDSC1 | 0.0010 | 0.2560 |
|
| M059J | AS601245 | GDSC1 | 0.0312 | 8.0000 |
|
| M059J | AS605240 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | ascorbate (vitamin C) | GDSC2 | 2.0011 | 2000.0000 |
|
| M059J | AST-1306 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | AT-7519 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | AT13148 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AT7867 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Avagacestat | GDSC1,GDSC2 | 0.0100 | 10.2400 |
|
| M059J | Axitinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| M059J | AZ20 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | AZ6102 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZ960 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD1208 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD1332 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD1480 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | AZD2014 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD3514 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | AZD3759 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | AZD4547 | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| M059J | AZD4877 | GDSC1 | 0.0002 | 0.0390 |
|
| M059J | AZD5153 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD5363 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD5438 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD5582 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD5991 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD6094 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | AZD6482 | GDSC1 | 0.0195 | 5.1200 |
|
| M059J | AZD6738 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | AZD7762 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| M059J | AZD7969 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | AZD8055 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | AZD8186 | GDSC1,GDSC2 | 0.0098 | 10.0000 |
|
| M059J | AZD8835 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | AZD8931 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | BAM7 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | BAY-61-3606 | GDSC1 | 0.0312 | 8.0000 |
|
| M059J | BDF00022089a | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | BDILV000379a | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | BDOCA000347a | GDSC2 | 0.0020 | 2.0000 |
|
| M059J | BDP-00009066 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Belinostat | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | BEN | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | Bexarotene | GDSC1 | 0.0312 | 8.0000 |
|
| M059J | BI-2536 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | BIBF-1120 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | BIBR-1532 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Bicalutamide | GDSC1 | 0.0040 | 10.0000 |
|
| M059J | BIX02189 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Bleomycin | GDSC1,GDSC2 | 0.0020 | 64.0000 |
|
| M059J | Bleomycin (10 uM) | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Bleomycin (50 uM) | GDSC1,GDSC2 | 0.0400 | 50.0000 |
|
| M059J | BMS-345541 | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| M059J | BMS-536924 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | BMS-754807 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Bortezomib | GDSC2 | 0.0000 | 0.0200 |
|
| M059J | Bosutinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | BPD-00008900 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | BPTES | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Brivanib, BMS-540215 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Bromosporine | GDSC2 | 0.0020 | 2.0000 |
|
| M059J | Bryostatin 1 | GDSC1 | 0.0000 | 0.0080 |
|
| M059J | Buparlisib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | BX-912 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | BX795 | GDSC1 | 0.0195 | 5.0000 |
|
| M059J | C-75 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Cabozantinib | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | Camptothecin | GDSC2 | 0.0001 | 0.1000 |
|
| M059J | CAP-232, TT-232, TLN-232 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Capivasertib | GDSC1 | 0.1172 | 30.0000 |
|
| M059J | Carmustine | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | CAY10566 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | CAY10603 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | CCT-018159 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | CCT007093 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | CCT245232 | GDSC1 | 0.0008 | 0.2000 |
|
| M059J | CCT245467 | GDSC1 | 0.0008 | 0.2000 |
|
| M059J | CD532 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | CDK9_5038 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | CDK9_5576 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Cediranib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Cetuximab | GDSC1 | 0.2570 | 65.8000 |
|
| M059J | CHIR-99021 | GDSC1 | 0.0100 | 10.0000 |
|
| M059J | CI-1033 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | CI-1040 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Cisplatin | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| M059J | CP466722 | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | CP724714 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | CPI-613 | GDSC1 | 1.0000 | 256.0000 |
|
| M059J | CPI-637 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Crizotinib | GDSC2,CCLE | 0.0010 | 10.0000 |
|
| M059J | CRT0105446 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | CRT0105950 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | CRT0160829 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | CT7033-2 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | CUDC-101 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | CX-5461 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Cyclophosphamide | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Cytarabine | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | CZC24832 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Dabrafenib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Dacarbazine | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | Dacinostat | GDSC1 | 0.0040 | 1.0240 |
|
| M059J | Dactinomycin | GDSC2 | 0.0000 | 0.8000 |
|
| M059J | Dactolisib | GDSC1,GDSC2 | 0.0003 | 0.2500 |
|
| M059J | Daporinad | GDSC1,GDSC2 | 0.0001 | 1.0000 |
|
| M059J | Dasatinib | GDSC2 | 0.0010 | 2.0000 |
|
| M059J | Dihydrorotenone | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | Dinaciclib | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | DMOG | GDSC1 | 15.6250 | 4000.0000 |
|
| M059J | Docetaxel | GDSC1,GDSC2 | 0.0000 | 3.0000 |
|
| M059J | Doramapimod | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Doxorubicin | GDSC1 | 0.0040 | 5.0000 |
|
| M059J | Dyrk1b_0191 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | eEF2K Inhibitor, A-484954 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Eg5_9814 | GDSC2 | 0.0001 | 0.1000 |
|
| M059J | EHT-1864 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Elephantin | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | Elesclomol | GDSC1 | 0.0008 | 0.2000 |
|
| M059J | Embelin | GDSC1 | 0.1250 | 32.0000 |
|
| M059J | Entinostat | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Entospletinib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Enzastaurin | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | EphB4_9721 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Epirubicin | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | Epothilone B | GDSC1 | 0.0001 | 0.0320 |
|
| M059J | EPZ004777 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | EPZ5676 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | ERK_2440 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | ERK_6604 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Erlotinib | GDSC2,CCLE | 0.0020 | 8.0000 |
|
| M059J | Etoposide | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | ETP-45835 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Fedratinib | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | FEN1_3940 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | FGFR_0939 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | FGFR_3831 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | FH535 | GDSC1 | 0.1250 | 32.0000 |
|
| M059J | Flavopiridol | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Fludarabine | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | FMK | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Foretinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | FR-180204 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | FS106 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | FS112 | GDSC1 | 0.0195 | 5.0000 |
|
| M059J | FTI-277 | GDSC1 | 0.0040 | 1.0240 |
|
| M059J | FTY-720 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Fulvestrant | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| M059J | FY012 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | FY026 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | FY069 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Gallibiscoquinazole | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | GDC0810 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Gefitinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | Gemcitabine | GDSC1,GDSC2 | 0.0001 | 10.0000 |
|
| M059J | Genentech Cpd 10 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | glutathione | GDSC2 | 0.6403 | 640.0000 |
|
| M059J | GNE-317 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK-J4 | GDSC1 | 0.1172 | 30.0000 |
|
| M059J | GSK-LSD1 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | GSK-LSD1-2HCl | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | GSK1059615 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | GSK1070916 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | GSK1904529A | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| M059J | GSK2110183B | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | GSK2256098C | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | GSK2276186C | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK2578215A | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK2606414 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK269962A | GDSC1 | 0.0195 | 5.0000 |
|
| M059J | GSK2801 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK2830371 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK2830371A | GDSC2 | 0.0030 | 10.0000 |
|
| M059J | GSK3337463A | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK343 | GDSC2 | 0.0010 | 10.0000 |
|
| M059J | GSK429286A | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | GSK591 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | GSK626616AC | GDSC2 | 0.0001 | 0.1000 |
|
| M059J | GSK650394 | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | GSK690693 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | GW-2580 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | GW441756 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | HG-5-113-01 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | HG-5-88-01 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | HG-6-71-01 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | HG6-64-1 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | HKMTI-1-005 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | I-BET-762 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| M059J | I-BET151 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | I-BRD9 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | IAP_5620 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | IAP_7638 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Ibrutinib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | IC-87114 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | ICL-SIRT078 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | ICL1100013 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Idelalisib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | IGF1R_3801 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | IGFR_3801 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | IMD-0354 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | IOX2 | GDSC1 | 0.0004 | 0.1000 |
|
| M059J | IPA-3 | GDSC1 | 0.1250 | 32.0000 |
|
| M059J | Ipatasertib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | IRAK4_4710 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Irinotecan | GDSC2 | 0.0050 | 10.0000 |
|
| M059J | Ispinesib Mesylate | GDSC1 | 0.0005 | 0.1280 |
|
| M059J | IWP-2 | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | JAK_8517 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | JAK1_3715 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | JAK1_8709 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | JAK3_7406 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | JNJ38877605 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | JNK Inhibitor VIII | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | JNK-9L | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | JQ1 | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| M059J | JQ12 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | JW-7-24-1 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | kb NB 142-70 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | KIN001-042 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | KIN001-236 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | KIN001-244 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | KIN001-260 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | KIN001-266 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | KIN001-270 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Kobe2602 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | KRAS (G12C) Inhibitor-12 | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | KU-55933 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | KU-60019 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | L-685458 | CCLE | 0.0025 | 8.0000 |
|
| M059J | L-Oxonoreleagnine | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | Lapatinib | GDSC2,CCLE | 0.0025 | 10.0000 |
|
| M059J | LBW242 | CCLE | 0.0025 | 8.0000 |
|
| M059J | LCL161 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | LDN-193189 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Leflunomide | GDSC2 | 0.1001 | 100.0000 |
|
| M059J | Lenalidomide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Lestaurtinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| M059J | LFM-A13 | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | LGK974 | GDSC1,GDSC2 | 0.0050 | 10.0000 |
|
| M059J | LIMK1 inhibitor BMS4 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Linifanib | GDSC1 | 0.0040 | 1.0240 |
|
| M059J | Linsitinib | GDSC1,GDSC2 | 0.0025 | 10.0000 |
|
| M059J | LJI308 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | LMB_AB1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | LMB_AB2 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | LMB_AB3 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | LMP744 | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | Luminespib | GDSC1,GDSC2 | 0.0003 | 1.0000 |
|
| M059J | LY2109761 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Masitinib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | MCT1_6447 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | MCT4_1422 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | MetAP2 Inhibitor, A832234 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Methotrexate | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| M059J | MG-132 | GDSC2 | 0.0156 | 4.0000 |
|
| M059J | Midostaurin | GDSC1 | 0.0020 | 0.5120 |
|
| M059J | MIM1 | GDSC1,GDSC2 | 0.0100 | 40.0000 |
|
| M059J | MIRA-1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Mirin | GDSC2 | 0.1001 | 100.0000 |
|
| M059J | Mitomycin-C | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | Mitoxantrone | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | MK-1775 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | MK-2206 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | MK-8776 | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | ML323 | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | MN-64 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Motesanib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| M059J | MPS-1-IN-1 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Mycophenolic acid | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | N-acetyl cysteine | GDSC2 | 2.0011 | 2000.0000 |
|
| M059J | N22899-6-C1 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | N23918-95-7 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | N24798-49-A1 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | N25720-51-A1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | N27922-53-1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | N29087-69-1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | N30652-18-1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Navitoclax | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| M059J | Nelarabine | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | NG-25 | GDSC1 | 0.0391 | 10.2400 |
|
| M059J | Nilotinib | GDSC1,GDSC2,CCLE | 0.0020 | 8.0000 |
|
| M059J | Niraparib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | NPK76-II-72-1 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | NSC-207895 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | NSC-87877 | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | NSC319726 | GDSC1 | 0.0010 | 0.2560 |
|
| M059J | NU7441 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| M059J | Nutlin-3a | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| M059J | NVP-ADW742 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | NVP-BHG712 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | NVP-TAE684 | CCLE | 0.0025 | 8.0000 |
|
| M059J | Obatoclax Mesylate | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| M059J | OF-1 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Olaparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Omipalisib | GDSC1 | 0.0005 | 0.1280 |
|
| M059J | OSI-027 | GDSC1,GDSC2 | 0.0040 | 20.0000 |
|
| M059J | OSI-930 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Osimertinib | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | OSU-03012 | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | OTX015 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Oxaliplatin | GDSC2 | 0.0100 | 20.0000 |
|
| M059J | P22077 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | PAC-1 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Paclitaxel | GDSC2,CCLE | 0.0000 | 8.0000 |
|
| M059J | PAK_5339 | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | Palbociclib | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| M059J | Panobinostat | GDSC1,CCLE | 0.0025 | 8.0000 |
|
| M059J | PARP_0108 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | PARP_9482 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | PARP_9495 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | Pazopanib | GDSC1 | 0.0312 | 8.0000 |
|
| M059J | PBD-288 | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | PCI-34051 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | PD0325901 | GDSC1,GDSC2,CCLE | 0.0003 | 8.0000 |
|
| M059J | PD173074 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| M059J | Pelitinib | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | Pemetrexed | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Pevonedistat | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | PF-00299804 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | PF-4708671 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | PF-562271 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | PFI-1 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | PFI3 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | PHA-665752 | CCLE | 0.0025 | 8.0000 |
|
| M059J | PHA-793887 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Phenformin | GDSC1 | 15.6250 | 4000.0000 |
|
| M059J | PI-103 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | PI3Ka_4409 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Picolinici-acid | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Pictilisib | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| M059J | PIK-93 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Pilaralisib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Piperlongumine | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | PLK_6522 | GDSC1 | 0.0024 | 0.6250 |
|
| M059J | PLX-4720 | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| M059J | Podophyllotoxin bromide | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | POMHEX | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Ponatinib | GDSC1 | 0.0020 | 0.5120 |
|
| M059J | PRIMA-1MET | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | PRT062607 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Pyridostatin | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | QL-VIII-58 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | QL-X-138 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | QL-XI-92 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | QL-XII-47 | GDSC1 | 0.0391 | 10.2400 |
|
| M059J | QL-XII-61 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | QS11 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Quizartinib | GDSC1 | 0.0040 | 1.0240 |
|
| M059J | RAF_9304 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | RAF265 | CCLE | 0.0025 | 8.0000 |
|
| M059J | Rapamycin | GDSC2 | 0.0000 | 0.0200 |
|
| M059J | Refametinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Ribociclib | GDSC2 | 0.0020 | 2.0000 |
|
| M059J | RO-3306 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Romidepsin | GDSC2 | 0.0000 | 0.0100 |
|
| M059J | rTRAIL | GDSC1 | 0.0004 | 0.1000 |
|
| M059J | RU-SKI 43 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Rucaparib | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| M059J | Ruxolitinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | RVX-208 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Sabutoclax | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Sapitinib | GDSC2 | 0.0050 | 10.0000 |
|
| M059J | Saracatinib | CCLE | 0.0025 | 8.0000 |
|
| M059J | Savolitinib | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | SB216763 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | SB505124 | GDSC1 | 0.0391 | 20.0000 |
|
| M059J | SB52334 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | SB590885 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| M059J | SCH772984 | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | Schweinfurthin A | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | Selisistat | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Selumetinib | GDSC1,GDSC2,CCLE | 0.0080 | 10.0000 |
|
| M059J | Sepantronium bromide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Serdemetan | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | SGC-CBP30 | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | SGC0946 | GDSC1,GDSC2 | 0.0005 | 0.5000 |
|
| M059J | Shikonin | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | Sinularin | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | SL0101 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | SN-38 | GDSC1,GDSC2 | 0.0000 | 0.1000 |
|
| M059J | SNX-2112 | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Sorafenib | GDSC2,CCLE | 0.0025 | 10.0000 |
|
| M059J | Sphingosine Kinase 1 Inhibitor II | GDSC1 | 0.0100 | 2.5600 |
|
| M059J | Staurosporine | GDSC2 | 0.0078 | 2.0000 |
|
| M059J | STF-62247 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | SU11274 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | T0901317 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | TAF1_5496 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | TAK-715 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Talazoparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Tamoxifen | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Tanespimycin | GDSC1,GDSC2,CCLE | 0.0010 | 8.0000 |
|
| M059J | TANK_1366 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | Taselisib | GDSC2 | 0.0040 | 10.0000 |
|
| M059J | Telomerase Inhibitor IX | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Temozolomide | GDSC1,GDSC2 | 0.0300 | 30.0000 |
|
| M059J | Temsirolimus | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| M059J | Teniposide | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | Tenovin-6 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Thapsigargin | GDSC1 | 0.0020 | 0.5120 |
|
| M059J | THR-101 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | THR-102 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | THR-103 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | THZ-1-87 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | THZ-2-102-1 | GDSC1 | 0.0098 | 2.5000 |
|
| M059J | THZ-2-49 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | THZ-2-98-01 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Tipifarnib | GDSC1 | 0.0625 | 16.0000 |
|
| M059J | Tivozanib | GDSC1 | 0.0005 | 0.1280 |
|
| M059J | TKI258 | CCLE | 0.0025 | 8.0000 |
|
| M059J | TL-1-85 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | TL-2-105 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | Topotecan | GDSC2,CCLE | 0.0025 | 8.0000 |
|
| M059J | Torin 2 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | torin2 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | TPCA-1 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Trametinib | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| M059J | Tretinoin | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Trichostatin A | GDSC1 | 0.0040 | 1.0240 |
|
| M059J | TTK_3146 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Tubastatin A | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | TW 37 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| M059J | TWS119 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | Ulixertinib | GDSC2 | 0.0020 | 10.0000 |
|
| M059J | ULK1_4989 | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | UMI-77 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | UNC0379 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | UNC0638 | GDSC1,GDSC2 | 0.0050 | 40.0000 |
|
| M059J | UNC0642 | GDSC1 | 0.0020 | 0.5000 |
|
| M059J | UNC1215 | GDSC1 | 0.0039 | 1.0000 |
|
| M059J | Uprosertib | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | VE-822 | GDSC2 | 0.0050 | 5.0000 |
|
| M059J | VE821 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Veliparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Venetoclax | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | Venotoclax | GDSC1 | 0.0010 | 0.2560 |
|
| M059J | Vinblastine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| M059J | Vincristine | GDSC2 | 0.0030 | 3.0000 |
|
| M059J | Vinorelbine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| M059J | Vismodegib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | VNLG-124 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | Vorinostat | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Voxtalisib | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | VSP34_8731 | GDSC2 | 0.0300 | 30.0000 |
|
| M059J | VTP-A | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | VTP-B | GDSC2 | 0.0010 | 1.0000 |
|
| M059J | VX-11e | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | VX-702 | GDSC1 | 0.0078 | 2.0000 |
|
| M059J | Wee1 Inhibitor | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| M059J | WEHI-539 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | WHI-P97 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | WIKI4 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Wnt-C59 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | WYE-125132 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | WZ3105 | GDSC1 | 0.0050 | 1.2800 |
|
| M059J | WZ4003 | GDSC2 | 0.0100 | 10.0000 |
|
| M059J | XAV939 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | XMD11-50 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | XMD11-85h | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | XMD13-2 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | XMD14-99 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | XMD15-27 | GDSC1 | 0.0400 | 10.2400 |
|
| M059J | XMD8-92 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Y-39983 | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | YK-4-279 | GDSC2 | 0.0200 | 20.0000 |
|
| M059J | YM201636 | GDSC1 | 0.0200 | 5.1200 |
|
| M059J | ZD-6474 | CCLE | 0.0025 | 8.0000 |
|
| M059J | ZG-10 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | Zibotentan | GDSC1 | 0.0781 | 20.0000 |
|
| M059J | ZL049 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | ZL109 | GDSC1 | 0.0391 | 10.0000 |
|
| M059J | ZM447439 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| M059J | Zoledronate | GDSC2 | 0.0020 | 2.0000 |
|
| M059J | ZSTK474 | GDSC1 | 0.0200 | 5.1200 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Drugs with highest and lowest IC50
Drugs with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Drugs with highest and lowest IC90
Drugs with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Drugs with highest and lowest AUC
Drugs with highest and lowest AUC