Cell Line : DOK
Cellosaurus Index : CVCL_1180
Cellosaurus ID : DOK
CCLE Name
: DOK_UPPER_AERODIGESTIVE_TRACT
GDSC1 Name
, GDSC2 Name
: DOK
Cancer Type : upper_aerodigestive_tract
Dataset : All
Drug Response Information
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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Cellosaurus ID | Drug Name | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| DOK | (5Z)-7-Oxozeaenol | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | 123138 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | 123829 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 150412 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 5-azacytidine | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | 5-Fluorouracil | GDSC1,GDSC2 | 0.0200 | 32.0000 |
|
| DOK | 50869 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 615590 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 630600 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 667880 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 720427 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 729189 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 741909 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | 743380 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | 765771 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | 776928 | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | A-366 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | A-83-01 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | ABT737 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Acetalax | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | ACY-1215 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Afatinib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| DOK | Afuresertib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AGI-5198 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AGI-6780 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| DOK | AGK-2 | GDSC2 | 0.0040 | 4.0000 |
|
| DOK | AICA Ribonucleotide | GDSC1 | 7.8125 | 2000.0000 |
|
| DOK | AKT inhibitor VIII | GDSC1 | 0.0100 | 10.2400 |
|
| DOK | Alectinib | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | Alisertib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| DOK | Alpelisib | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | alpha-lipoic acid | GDSC2 | 0.1211 | 121.0000 |
|
| DOK | AMG-319 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Amuvatinib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Apitolisib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | AR-42 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | Ara-G | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | ARRY-520 | GDSC1 | 0.0010 | 0.2560 |
|
| DOK | AS601245 | GDSC1 | 0.0312 | 8.0000 |
|
| DOK | AS605240 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | ascorbate (vitamin C) | GDSC2 | 2.0011 | 2000.0000 |
|
| DOK | AST-1306 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | AT-7519 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | AT13148 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AT7867 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Avagacestat | GDSC1,GDSC2 | 0.0100 | 10.2400 |
|
| DOK | Axitinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | AZ20 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | AZ6102 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZ960 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD1208 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD1332 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD1480 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | AZD2014 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD3514 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | AZD3759 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | AZD4547 | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| DOK | AZD4877 | GDSC1 | 0.0002 | 0.0390 |
|
| DOK | AZD5153 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD5363 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD5438 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD5582 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD5991 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD6094 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | AZD6482 | GDSC1 | 0.0195 | 5.1200 |
|
| DOK | AZD6738 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | AZD7762 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | AZD7969 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | AZD8055 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | AZD8186 | GDSC1,GDSC2 | 0.0098 | 10.0000 |
|
| DOK | AZD8835 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | AZD8931 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | BAM7 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | BAY-61-3606 | GDSC1 | 0.0312 | 8.0000 |
|
| DOK | BDF00022089a | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | BDILV000379a | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | BDOCA000347a | GDSC2 | 0.0020 | 2.0000 |
|
| DOK | BDP-00009066 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Belinostat | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | BEN | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | Bexarotene | GDSC1 | 0.0312 | 8.0000 |
|
| DOK | BI-2536 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | BIBF-1120 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | BIBR-1532 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Bicalutamide | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | BIX02189 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Bleomycin | GDSC1,GDSC2 | 0.0020 | 64.0000 |
|
| DOK | Bleomycin (10 uM) | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Bleomycin (50 uM) | GDSC1,GDSC2 | 0.0400 | 50.0000 |
|
| DOK | BMS-345541 | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| DOK | BMS-536924 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | BMS-754807 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Bortezomib | GDSC2 | 0.0000 | 0.0200 |
|
| DOK | Bosutinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | BPD-00008900 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | BPTES | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Brivanib, BMS-540215 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Bromosporine | GDSC2 | 0.0020 | 2.0000 |
|
| DOK | Bryostatin 1 | GDSC1 | 0.0000 | 0.0080 |
|
| DOK | Buparlisib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | BX-912 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | BX795 | GDSC1 | 0.0195 | 5.0000 |
|
| DOK | C-75 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Cabozantinib | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | Camptothecin | GDSC2 | 0.0001 | 0.1000 |
|
| DOK | CAP-232, TT-232, TLN-232 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Capivasertib | GDSC1 | 0.1172 | 30.0000 |
|
| DOK | Carmustine | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | CAY10566 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | CAY10603 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | CCT-018159 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | CCT007093 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | CCT245232 | GDSC1 | 0.0008 | 0.2000 |
|
| DOK | CCT245467 | GDSC1 | 0.0008 | 0.2000 |
|
| DOK | CD532 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | CDK9_5038 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | CDK9_5576 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Cediranib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | CHIR-99021 | GDSC1 | 0.0100 | 10.0000 |
|
| DOK | CI-1033 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | CI-1040 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Cisplatin | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| DOK | CP466722 | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | CP724714 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | CPI-613 | GDSC1 | 1.0000 | 256.0000 |
|
| DOK | CPI-637 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Crizotinib | GDSC2 | 0.0010 | 10.0000 |
|
| DOK | CRT0105446 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | CRT0105950 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | CRT0160829 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | CT7033-2 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | CUDC-101 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | CX-5461 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Cyclophosphamide | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Cytarabine | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | CZC24832 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Dabrafenib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Dacarbazine | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | Dacinostat | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | Dactinomycin | GDSC2 | 0.0000 | 0.8000 |
|
| DOK | Dactolisib | GDSC1,GDSC2 | 0.0003 | 0.2500 |
|
| DOK | Daporinad | GDSC1,GDSC2 | 0.0001 | 1.0000 |
|
| DOK | Dasatinib | GDSC2 | 0.0010 | 2.0000 |
|
| DOK | Dihydrorotenone | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | Dinaciclib | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | DMOG | GDSC1 | 15.6250 | 4000.0000 |
|
| DOK | Docetaxel | GDSC1,GDSC2 | 0.0000 | 3.0000 |
|
| DOK | Doramapimod | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Doxorubicin | GDSC1 | 0.0040 | 5.0000 |
|
| DOK | Dyrk1b_0191 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | eEF2K Inhibitor, A-484954 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Eg5_9814 | GDSC2 | 0.0001 | 0.1000 |
|
| DOK | EHT-1864 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Elephantin | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | Elesclomol | GDSC1 | 0.0008 | 0.2000 |
|
| DOK | Embelin | GDSC1 | 0.1250 | 32.0000 |
|
| DOK | Entinostat | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Entospletinib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Enzastaurin | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | EphB4_9721 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Epirubicin | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | Epothilone B | GDSC1 | 0.0001 | 0.0320 |
|
| DOK | EPZ004777 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | EPZ5676 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | ERK_2440 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | ERK_6604 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Erlotinib | GDSC2 | 0.0020 | 2.0000 |
|
| DOK | Etoposide | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | ETP-45835 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Fedratinib | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | FEN1_3940 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | FGFR_0939 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | FGFR_3831 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | FH535 | GDSC1 | 0.1250 | 32.0000 |
|
| DOK | Flavopiridol | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Fludarabine | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | Foretinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | FR-180204 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | FS106 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | FS112 | GDSC1 | 0.0195 | 5.0000 |
|
| DOK | FTI-277 | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | FTY-720 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Fulvestrant | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| DOK | FY012 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | FY026 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | FY069 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Gallibiscoquinazole | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | GDC0810 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Gefitinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | Gemcitabine | GDSC1,GDSC2 | 0.0001 | 10.0000 |
|
| DOK | Genentech Cpd 10 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | glutathione | GDSC2 | 0.6403 | 640.0000 |
|
| DOK | GNE-317 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK-J4 | GDSC1 | 0.1172 | 30.0000 |
|
| DOK | GSK-LSD1 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | GSK-LSD1-2HCl | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | GSK1059615 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | GSK1070916 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | GSK1904529A | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| DOK | GSK2110183B | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | GSK2256098C | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | GSK2276186C | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK2578215A | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK2606414 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK269962A | GDSC1 | 0.0195 | 5.0000 |
|
| DOK | GSK2801 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK2830371 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK2830371A | GDSC2 | 0.0030 | 10.0000 |
|
| DOK | GSK3337463A | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK343 | GDSC2 | 0.0010 | 10.0000 |
|
| DOK | GSK429286A | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | GSK591 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | GSK626616AC | GDSC2 | 0.0001 | 0.1000 |
|
| DOK | GSK650394 | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | GSK690693 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | GW-2580 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | GW441756 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | HG-5-113-01 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | HG-5-88-01 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | HG-6-71-01 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | HG6-64-1 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | HKMTI-1-005 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | I-BET-762 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| DOK | I-BET151 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | I-BRD9 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | IAP_5620 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | IAP_7638 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Ibrutinib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | IC-87114 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | ICL-SIRT078 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | ICL1100013 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Idelalisib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | IGF1R_3801 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | IGFR_3801 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | IMD-0354 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | IOX2 | GDSC1 | 0.0004 | 0.1000 |
|
| DOK | IPA-3 | GDSC1 | 0.1250 | 32.0000 |
|
| DOK | Ipatasertib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | IRAK4_4710 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Irinotecan | GDSC2 | 0.0050 | 10.0000 |
|
| DOK | Ispinesib Mesylate | GDSC1 | 0.0005 | 0.1280 |
|
| DOK | IWP-2 | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | JAK_8517 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | JAK1_3715 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | JAK1_8709 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | JAK3_7406 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | JNJ38877605 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | JNK Inhibitor VIII | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | JNK-9L | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | JQ1 | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| DOK | JQ12 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | JW-7-24-1 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | kb NB 142-70 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | KIN001-042 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | KIN001-236 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | KIN001-244 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | KIN001-260 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | KIN001-266 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | KIN001-270 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Kobe2602 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | KRAS (G12C) Inhibitor-12 | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | KU-55933 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | KU-60019 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | L-Oxonoreleagnine | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | Lapatinib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LCL161 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LDN-193189 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Leflunomide | GDSC2 | 0.1001 | 100.0000 |
|
| DOK | Lenalidomide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Lestaurtinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | LFM-A13 | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | LGK974 | GDSC1,GDSC2 | 0.0050 | 10.0000 |
|
| DOK | LIMK1 inhibitor BMS4 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Linifanib | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | Linsitinib | GDSC1,GDSC2 | 0.0025 | 10.0000 |
|
| DOK | LJI308 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LMB_AB1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LMB_AB2 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LMB_AB3 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | LMP744 | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | Luminespib | GDSC1,GDSC2 | 0.0003 | 1.0000 |
|
| DOK | LY2109761 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Masitinib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | MCT1_6447 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | MCT4_1422 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | MetAP2 Inhibitor, A832234 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Methotrexate | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| DOK | MG-132 | GDSC2 | 0.0156 | 4.0000 |
|
| DOK | Midostaurin | GDSC1 | 0.0020 | 0.5120 |
|
| DOK | MIM1 | GDSC1,GDSC2 | 0.0100 | 40.0000 |
|
| DOK | MIRA-1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Mirin | GDSC2 | 0.1001 | 100.0000 |
|
| DOK | Mitomycin-C | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | Mitoxantrone | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | MK-1775 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | MK-2206 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | MK-8776 | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | ML323 | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | MN-64 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Motesanib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | MPS-1-IN-1 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Mycophenolic acid | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | N-acetyl cysteine | GDSC2 | 2.0011 | 2000.0000 |
|
| DOK | N22899-6-C1 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | N23918-95-7 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | N24798-49-A1 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | N25720-51-A1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | N27922-53-1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | N29087-69-1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | N30652-18-1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Navitoclax | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| DOK | Nelarabine | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | NG-25 | GDSC1 | 0.0391 | 10.2400 |
|
| DOK | Nilotinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| DOK | Niraparib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | NPK76-II-72-1 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | NSC-207895 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | NSC-87877 | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | NSC319726 | GDSC1 | 0.0010 | 0.2560 |
|
| DOK | NU7441 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | Nutlin-3a | GDSC1,GDSC2 | 0.0080 | 10.0000 |
|
| DOK | NVP-ADW742 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | NVP-BHG712 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Obatoclax Mesylate | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| DOK | OF-1 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Olaparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Omipalisib | GDSC1 | 0.0005 | 0.1280 |
|
| DOK | OSI-027 | GDSC1,GDSC2 | 0.0040 | 20.0000 |
|
| DOK | OSI-930 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Osimertinib | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | OSU-03012 | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | OTX015 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Oxaliplatin | GDSC2 | 0.0100 | 20.0000 |
|
| DOK | P22077 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | PAC-1 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Paclitaxel | GDSC2 | 0.0000 | 0.0100 |
|
| DOK | PAK_5339 | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | Palbociclib | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| DOK | Panobinostat | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | PARP_0108 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | PARP_9482 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | PARP_9495 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | Pazopanib | GDSC1 | 0.0312 | 8.0000 |
|
| DOK | PBD-288 | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | PCI-34051 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | PD0325901 | GDSC1,GDSC2 | 0.0003 | 2.5000 |
|
| DOK | PD173074 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| DOK | Pelitinib | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | Pemetrexed | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Pevonedistat | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | PF-00299804 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | PF-4708671 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | PF-562271 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | PFI-1 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | PFI3 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | PHA-793887 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Phenformin | GDSC1 | 15.6250 | 4000.0000 |
|
| DOK | PI-103 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | PI3Ka_4409 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Picolinici-acid | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Pictilisib | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| DOK | PIK-93 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Pilaralisib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Piperlongumine | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | PLK_6522 | GDSC1 | 0.0024 | 0.6250 |
|
| DOK | PLX-4720 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Podophyllotoxin bromide | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | POMHEX | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Ponatinib | GDSC1 | 0.0020 | 0.5120 |
|
| DOK | PRIMA-1MET | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | PRT062607 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Pyridostatin | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | QL-VIII-58 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | QL-X-138 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | QL-XI-92 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | QL-XII-47 | GDSC1 | 0.0391 | 10.2400 |
|
| DOK | QL-XII-61 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | QS11 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Quizartinib | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | RAF_9304 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Rapamycin | GDSC2 | 0.0000 | 0.0200 |
|
| DOK | Refametinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Ribociclib | GDSC2 | 0.0020 | 2.0000 |
|
| DOK | RO-3306 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Romidepsin | GDSC2 | 0.0000 | 0.0100 |
|
| DOK | rTRAIL | GDSC1 | 0.0004 | 0.1000 |
|
| DOK | RU-SKI 43 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Rucaparib | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| DOK | Ruxolitinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | RVX-208 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Sabutoclax | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Sapitinib | GDSC2 | 0.0050 | 10.0000 |
|
| DOK | Savolitinib | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | SB216763 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | SB505124 | GDSC1 | 0.0391 | 20.0000 |
|
| DOK | SB52334 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | SB590885 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| DOK | SCH772984 | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | Schweinfurthin A | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | Selisistat | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Selumetinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | Sepantronium bromide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Serdemetan | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | SGC-CBP30 | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | SGC0946 | GDSC1,GDSC2 | 0.0005 | 0.5000 |
|
| DOK | Shikonin | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | Sinularin | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | SL0101 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | SN-38 | GDSC1,GDSC2 | 0.0000 | 0.1000 |
|
| DOK | SNX-2112 | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Sorafenib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Sphingosine Kinase 1 Inhibitor II | GDSC1 | 0.0100 | 2.5600 |
|
| DOK | Staurosporine | GDSC2 | 0.0078 | 2.0000 |
|
| DOK | STF-62247 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | SU11274 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | T0901317 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | TAF1_5496 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | TAK-715 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Talazoparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Tamoxifen | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Tanespimycin | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| DOK | TANK_1366 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | Taselisib | GDSC2 | 0.0040 | 10.0000 |
|
| DOK | Telomerase Inhibitor IX | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Temozolomide | GDSC1,GDSC2 | 0.0300 | 30.0000 |
|
| DOK | Temsirolimus | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| DOK | Teniposide | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | Tenovin-6 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Thapsigargin | GDSC1 | 0.0020 | 0.5120 |
|
| DOK | THR-101 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | THR-102 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | THR-103 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | THZ-1-87 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | THZ-2-102-1 | GDSC1 | 0.0098 | 2.5000 |
|
| DOK | THZ-2-49 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | THZ-2-98-01 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Tipifarnib | GDSC1 | 0.0625 | 16.0000 |
|
| DOK | Tivozanib | GDSC1 | 0.0005 | 0.1280 |
|
| DOK | TL-1-85 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | TL-2-105 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | Topotecan | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | Torin 2 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | torin2 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | TPCA-1 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Trametinib | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| DOK | Tretinoin | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Trichostatin A | GDSC1 | 0.0040 | 1.0240 |
|
| DOK | TTK_3146 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Tubastatin A | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | TW 37 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| DOK | TWS119 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | Ulixertinib | GDSC2 | 0.0020 | 10.0000 |
|
| DOK | ULK1_4989 | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | UMI-77 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | UNC0379 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | UNC0638 | GDSC1,GDSC2 | 0.0050 | 40.0000 |
|
| DOK | UNC0642 | GDSC1 | 0.0020 | 0.5000 |
|
| DOK | UNC1215 | GDSC1 | 0.0039 | 1.0000 |
|
| DOK | Uprosertib | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | VE-822 | GDSC2 | 0.0050 | 5.0000 |
|
| DOK | VE821 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Veliparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Venetoclax | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | Venotoclax | GDSC1 | 0.0010 | 0.2560 |
|
| DOK | Vinblastine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| DOK | Vincristine | GDSC2 | 0.0030 | 3.0000 |
|
| DOK | Vinorelbine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| DOK | Vismodegib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | VNLG-124 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | Vorinostat | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Voxtalisib | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | VSP34_8731 | GDSC2 | 0.0300 | 30.0000 |
|
| DOK | VTP-A | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | VTP-B | GDSC2 | 0.0010 | 1.0000 |
|
| DOK | VX-11e | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | VX-702 | GDSC1 | 0.0078 | 2.0000 |
|
| DOK | Wee1 Inhibitor | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | WEHI-539 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | WHI-P97 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | WIKI4 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | Wnt-C59 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | WYE-125132 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | WZ3105 | GDSC1 | 0.0050 | 1.2800 |
|
| DOK | WZ4003 | GDSC2 | 0.0100 | 10.0000 |
|
| DOK | XAV939 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| DOK | XMD11-50 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | XMD11-85h | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | XMD13-2 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | XMD14-99 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | XMD15-27 | GDSC1 | 0.0400 | 10.2400 |
|
| DOK | XMD8-92 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Y-39983 | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | YK-4-279 | GDSC2 | 0.0200 | 20.0000 |
|
| DOK | YM201636 | GDSC1 | 0.0200 | 5.1200 |
|
| DOK | ZG-10 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | Zibotentan | GDSC1 | 0.0781 | 20.0000 |
|
| DOK | ZL049 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | ZL109 | GDSC1 | 0.0391 | 10.0000 |
|
| DOK | ZM447439 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| DOK | Zoledronate | GDSC2 | 0.0020 | 2.0000 |
|
| DOK | ZSTK474 | GDSC1 | 0.0200 | 5.1200 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Drugs with highest and lowest IC50
Drugs with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Drugs with highest and lowest IC90
Drugs with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Drugs with highest and lowest AUC
Drugs with highest and lowest AUC