Cell Line : HLE
Cellosaurus Index : CVCL_1281
Cellosaurus ID : HLE
CCLE Name
: HLE_LIVER
CTRP2 Name
, GDSC1 Name
, GDSC2 Name
: HLE
Cancer Type : liver
Dataset : All
Drug Response Information
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Cellosaurus ID | Drug Name | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| HLE | (5Z)-7-Oxozeaenol | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | 123138 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | 123829 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 150412 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 5-azacytidine | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | 5-Fluorouracil | GDSC1,GDSC2 | 0.0200 | 32.0000 |
|
| HLE | 50869 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 615590 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 630600 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 667880 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 720427 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 729189 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 741909 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | 743380 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | 765771 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | 776928 | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | 965-D2 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | 993-D2 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | A-366 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | A-83-01 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | ABT737 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Acetalax | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | ACY-1215 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | AEW541 | CCLE | 0.0025 | 8.0000 |
|
| HLE | Afatinib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| HLE | Afuresertib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AGI-5198 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AGI-6780 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| HLE | AGK-2 | GDSC2 | 0.0040 | 4.0000 |
|
| HLE | AICA Ribonucleotide | GDSC1 | 7.8125 | 2000.0000 |
|
| HLE | AKT inhibitor VIII | GDSC1 | 0.0100 | 10.2400 |
|
| HLE | Alectinib | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | Alisertib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| HLE | Alpelisib | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | alpha-lipoic acid | GDSC2 | 0.1211 | 121.0000 |
|
| HLE | AMG-319 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Amuvatinib | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Apitolisib | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | AR-42 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | Ara-G | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | ARRY-520 | GDSC1 | 0.0010 | 0.2560 |
|
| HLE | AS601245 | GDSC1 | 0.0312 | 8.0000 |
|
| HLE | AS605240 | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | ascorbate (vitamin C) | GDSC2 | 2.0011 | 2000.0000 |
|
| HLE | AST-1306 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | AT-7519 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | AT13148 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AT7867 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Avagacestat | GDSC1,GDSC2 | 0.0100 | 10.2400 |
|
| HLE | Axitinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | AZ20 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | AZ6102 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZ960 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD1208 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD1332 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD1480 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | AZD2014 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD3514 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | AZD3759 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | AZD4547 | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| HLE | AZD4877 | GDSC1 | 0.0002 | 0.0390 |
|
| HLE | AZD5153 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD5363 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD5438 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD5582 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD5991 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD6094 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | AZD6482 | GDSC1 | 0.0195 | 5.1200 |
|
| HLE | AZD6738 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | AZD7762 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | AZD7969 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | AZD8055 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | AZD8186 | GDSC1,GDSC2 | 0.0098 | 10.0000 |
|
| HLE | AZD8835 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | AZD8931 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAM7 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | BAY ACCi | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAY AKT1 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAY-61-3606 | GDSC1 | 0.0312 | 8.0000 |
|
| HLE | BAY-HDAC11_1 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAY-HDAC11_2 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAY-HDAC11_4 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | BAY-MPS-combo 2 (paclitaxel 1 uM) | GDSC1 | 0.0039 | 1.0000 |
|
| HLE | BAY-MPS-combo-1 (paclitaxel 5 uM) | GDSC1 | 0.0039 | 1.0000 |
|
| HLE | BAY-MPS1 | GDSC1 | 0.0117 | 3.0000 |
|
| HLE | BDF00022089a | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | BDILV000379a | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | BDOCA000347a | GDSC2 | 0.0020 | 2.0000 |
|
| HLE | BDP-00009066 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Belinostat | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | BEN | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | Bexarotene | GDSC1 | 0.0312 | 8.0000 |
|
| HLE | BI-2536 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | BIBF-1120 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | BIBR-1532 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Bicalutamide | GDSC1 | 0.0040 | 10.0000 |
|
| HLE | BIX02189 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Bleomycin | GDSC1,GDSC2 | 0.0020 | 64.0000 |
|
| HLE | Bleomycin (10 uM) | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Bleomycin (50 uM) | GDSC1,GDSC2 | 0.0400 | 50.0000 |
|
| HLE | BMS-345541 | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| HLE | BMS-536924 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | BMS-754807 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Bortezomib | GDSC2 | 0.0000 | 0.0200 |
|
| HLE | Bosutinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | BPD-00008900 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | BPTES | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Brivanib, BMS-540215 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Bromosporine | GDSC2 | 0.0020 | 2.0000 |
|
| HLE | Bryostatin 1 | GDSC1 | 0.0000 | 0.0080 |
|
| HLE | Buparlisib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | BX-912 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | BX795 | GDSC1 | 0.0195 | 5.0000 |
|
| HLE | C-75 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Cabozantinib | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | Camptothecin | GDSC2 | 0.0001 | 0.1000 |
|
| HLE | CAP-232, TT-232, TLN-232 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Capivasertib | GDSC1 | 0.1172 | 30.0000 |
|
| HLE | Carmustine | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | CAY10566 | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | CAY10603 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | CCT-018159 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | CCT007093 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | CCT245232 | GDSC1 | 0.0008 | 0.2000 |
|
| HLE | CCT245467 | GDSC1 | 0.0008 | 0.2000 |
|
| HLE | CD532 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | CDK9_5038 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | CDK9_5576 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Cediranib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Cetuximab | GDSC1 | 0.2570 | 65.8000 |
|
| HLE | CHIR-99021 | GDSC1 | 0.0100 | 10.0000 |
|
| HLE | CI-1033 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | CI-1040 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Cisplatin | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| HLE | CP466722 | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | CP724714 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | CPI-613 | GDSC1 | 1.0000 | 256.0000 |
|
| HLE | CPI-637 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Crizotinib | GDSC2,CCLE | 0.0010 | 10.0000 |
|
| HLE | CRT0105446 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | CRT0105950 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | CRT0160829 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | CT7033-2 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | CUDC-101 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | CX-5461 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Cyclophosphamide | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Cytarabine | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | CZC24832 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Dabrafenib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Dacarbazine | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | Dacinostat | GDSC1 | 0.0040 | 1.0240 |
|
| HLE | Dactinomycin | GDSC2 | 0.0000 | 0.8000 |
|
| HLE | Dactolisib | GDSC1,GDSC2 | 0.0003 | 0.2500 |
|
| HLE | Daporinad | GDSC1,GDSC2 | 0.0001 | 1.0000 |
|
| HLE | Dasatinib | GDSC2 | 0.0010 | 2.0000 |
|
| HLE | Dihydrorotenone | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | Dinaciclib | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | DMOG | GDSC1 | 15.6250 | 4000.0000 |
|
| HLE | Docetaxel | GDSC1,GDSC2 | 0.0000 | 3.0000 |
|
| HLE | Doramapimod | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Doxorubicin | GDSC1 | 0.0040 | 5.0000 |
|
| HLE | Dyrk1b_0191 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | eEF2K Inhibitor, A-484954 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Eg5_9814 | GDSC2 | 0.0001 | 0.1000 |
|
| HLE | EHT-1864 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Elephantin | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | Elesclomol | GDSC1 | 0.0008 | 0.2000 |
|
| HLE | Embelin | GDSC1 | 0.1250 | 32.0000 |
|
| HLE | Entinostat | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Entospletinib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Enzastaurin | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | EphB4_9721 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Epirubicin | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | Epothilone B | GDSC1 | 0.0001 | 0.0320 |
|
| HLE | EPZ004777 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | EPZ5676 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | ERK_2440 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | ERK_6604 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Erlotinib | GDSC2,CCLE | 0.0020 | 8.0000 |
|
| HLE | Etoposide | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | ETP-45835 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Fedratinib | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | FEN1_3940 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | FGFR_0939 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | FGFR_3831 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | FH535 | GDSC1 | 0.1250 | 32.0000 |
|
| HLE | Flavopiridol | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Fludarabine | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | FMK | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | Foretinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | FR-180204 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | FS106 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | FS112 | GDSC1 | 0.0195 | 10.0000 |
|
| HLE | FTI-277 | GDSC1 | 0.0040 | 1.0240 |
|
| HLE | FTY-720 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Fulvestrant | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| HLE | FY012 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | FY026 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | FY069 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Gallibiscoquinazole | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | GDC0810 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Gefitinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | Gemcitabine | GDSC1,GDSC2 | 0.0001 | 10.0000 |
|
| HLE | Genentech Cpd 10 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | glutathione | GDSC2 | 0.6403 | 640.0000 |
|
| HLE | GNE-317 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK-J4 | GDSC1 | 0.1172 | 30.0000 |
|
| HLE | GSK-LSD1 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | GSK-LSD1-2HCl | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | GSK1059615 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | GSK1070916 | GDSC1 | 0.0100 | 10.2400 |
|
| HLE | GSK1904529A | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| HLE | GSK2110183B | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | GSK2256098C | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | GSK2276186C | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK2578215A | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK2606414 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK269962A | GDSC1 | 0.0195 | 5.0000 |
|
| HLE | GSK2801 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK2830371 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK2830371A | GDSC2 | 0.0030 | 10.0000 |
|
| HLE | GSK3337463A | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK343 | GDSC2 | 0.0010 | 10.0000 |
|
| HLE | GSK429286A | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | GSK591 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | GSK626616AC | GDSC2 | 0.0001 | 0.1000 |
|
| HLE | GSK650394 | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | GSK690693 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | GW-2580 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | GW441756 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | HG6-64-1 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | HKMTI-1-005 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | I-BET-762 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| HLE | I-BET151 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | I-BRD9 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | I-CBP112 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | IAP_5620 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | IAP_7638 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Ibrutinib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | IC-87114 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | ICL-SIRT078 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | ICL1100013 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Idelalisib | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | IGF1R_3801 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | IGFR_3801 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | IMD-0354 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | IOX2 | GDSC1 | 0.0004 | 0.1000 |
|
| HLE | IPA-3 | GDSC1 | 0.1250 | 32.0000 |
|
| HLE | Ipatasertib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | IRAK4_4710 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Irinotecan | GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | Ispinesib Mesylate | GDSC1 | 0.0005 | 0.1280 |
|
| HLE | IWP-2 | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | JAK_8517 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | JAK1_3715 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | JAK1_8709 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | JAK3_7406 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | JNJ38877605 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | JNK Inhibitor VIII | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | JNK-9L | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | JQ1 | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| HLE | JQ12 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | JW-7-24-1 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | kb NB 142-70 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | KIN001-042 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | KIN001-236 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | KIN001-244 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | KIN001-260 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | KIN001-266 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | KIN001-270 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Kobe2602 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | KRAS (G12C) Inhibitor-12 | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | KU-55933 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | KU-60019 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | L-685458 | CCLE | 0.0025 | 8.0000 |
|
| HLE | L-Oxonoreleagnine | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | Lapatinib | GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | LBW242 | CCLE | 0.0025 | 8.0000 |
|
| HLE | LCL161 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | LDN-193189 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Leflunomide | GDSC2 | 0.1001 | 100.0000 |
|
| HLE | Lenalidomide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Lestaurtinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| HLE | LFM-A13 | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | LGK974 | GDSC1,GDSC2 | 0.0050 | 10.0000 |
|
| HLE | LIMK1 inhibitor BMS4 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Linifanib | GDSC1 | 0.0040 | 1.0240 |
|
| HLE | Linsitinib | GDSC1,GDSC2 | 0.0025 | 10.0000 |
|
| HLE | LJI308 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | LMB_AB1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | LMB_AB2 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | LMB_AB3 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | LMP744 | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | Luminespib | GDSC1,GDSC2 | 0.0003 | 1.0000 |
|
| HLE | LY2109761 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Masitinib | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | MCT1_6447 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | MCT4_1422 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | MetAP2 Inhibitor, A832234 | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Methotrexate | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| HLE | MG-132 | GDSC2 | 0.0156 | 4.0000 |
|
| HLE | Midostaurin | GDSC1 | 0.0020 | 0.5120 |
|
| HLE | MIM1 | GDSC1,GDSC2 | 0.0100 | 40.0000 |
|
| HLE | MIRA-1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Mirin | GDSC1,GDSC2 | 0.1001 | 100.0000 |
|
| HLE | Mitomycin-C | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | Mitoxantrone | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | MK-1775 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | MK-2206 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | MK-8776 | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | ML323 | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | MN-64 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Motesanib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | MPS-1-IN-1 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Mycophenolic acid | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | N-acetyl cysteine | GDSC2 | 2.0011 | 2000.0000 |
|
| HLE | N22899-6-C1 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | N23918-95-7 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | N24798-49-A1 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | N25720-51-A1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | N27922-53-1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | N29087-69-1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | N30652-18-1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Navitoclax | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| HLE | Nelarabine | GDSC2 | 0.0200 | 20.0000 |
|
| HLE | NG-25 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Nilotinib | GDSC1,GDSC2,CCLE | 0.0020 | 8.0000 |
|
| HLE | Niraparib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | NPK76-II-72-1 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | NSC-207895 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | NSC-87877 | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | NSC319726 | GDSC1 | 0.0010 | 0.2560 |
|
| HLE | NU7441 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | Nutlin-3a | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | NVP-ADW742 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | NVP-BHG712 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | NVP-TAE684 | CCLE | 0.0025 | 8.0000 |
|
| HLE | Obatoclax Mesylate | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| HLE | OF-1 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Olaparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Omipalisib | GDSC1 | 0.0005 | 0.1280 |
|
| HLE | OSI-027 | GDSC1,GDSC2 | 0.0040 | 20.0000 |
|
| HLE | OSI-930 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Osimertinib | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | OSU-03012 | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | OTX015 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Oxaliplatin | GDSC2 | 0.0100 | 20.0000 |
|
| HLE | P22077 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | PAC-1 | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Paclitaxel | GDSC2,CCLE | 0.0000 | 8.0000 |
|
| HLE | PAK_5339 | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | Palbociclib | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | Panobinostat | GDSC1,CCLE | 0.0025 | 8.0000 |
|
| HLE | PARP_0108 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | PARP_9482 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | PARP_9495 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | Pazopanib | GDSC1 | 0.0312 | 8.0000 |
|
| HLE | PBD-288 | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | PCI-34051 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | PD0325901 | GDSC1,GDSC2,CCLE | 0.0003 | 8.0000 |
|
| HLE | PD173074 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| HLE | Pelitinib | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | Pemetrexed | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Pevonedistat | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| HLE | PF-00299804 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | PF-4708671 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | PF-562271 | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | PFI-1 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | PFI3 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | PHA-665752 | CCLE | 0.0025 | 8.0000 |
|
| HLE | PHA-793887 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Phenformin | GDSC1 | 15.6250 | 4000.0000 |
|
| HLE | PI-103 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | PI3Ka_4409 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Picolinici-acid | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Pictilisib | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| HLE | PIK-93 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Pilaralisib | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Piperlongumine | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | PLK_6522 | GDSC1 | 0.0024 | 0.6250 |
|
| HLE | PLX-4720 | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | Podophyllotoxin bromide | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | POMHEX | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Ponatinib | GDSC1 | 0.0020 | 0.5120 |
|
| HLE | PRIMA-1MET | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | PRT062607 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Pyridostatin | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | QL-X-138 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | QL-XI-92 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | QL-XII-47 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | QS11 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Quizartinib | GDSC1 | 0.0040 | 1.0240 |
|
| HLE | RAF_9304 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | RAF265 | CCLE | 0.0025 | 8.0000 |
|
| HLE | Rapamycin | GDSC2 | 0.0000 | 0.0200 |
|
| HLE | Refametinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Ribociclib | GDSC2 | 0.0020 | 2.0000 |
|
| HLE | RO-3306 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Romidepsin | GDSC2 | 0.0000 | 0.0100 |
|
| HLE | rTRAIL | GDSC1 | 0.0004 | 0.1000 |
|
| HLE | RU-SKI 43 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Rucaparib | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| HLE | Ruxolitinib | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| HLE | RVX-208 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Sabutoclax | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Sapitinib | GDSC2 | 0.0050 | 10.0000 |
|
| HLE | Saracatinib | CCLE | 0.0025 | 8.0000 |
|
| HLE | Savolitinib | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | SB216763 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | SB505124 | GDSC1 | 0.0391 | 20.0000 |
|
| HLE | SB52334 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | SB590885 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| HLE | SCH772984 | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | Schweinfurthin A | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | Selisistat | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Selumetinib | GDSC1,GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | Sepantronium bromide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Serdemetan | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | SGC-CBP30 | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | SGC0946 | GDSC1,GDSC2 | 0.0005 | 0.5000 |
|
| HLE | Shikonin | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | Sinularin | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | SL0101 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | SN-38 | GDSC1,GDSC2 | 0.0000 | 0.1000 |
|
| HLE | SNX-2112 | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Sorafenib | GDSC2,CCLE | 0.0025 | 10.0000 |
|
| HLE | Sphingosine Kinase 1 Inhibitor II | GDSC1 | 0.0100 | 2.5600 |
|
| HLE | Staurosporine | GDSC2 | 0.0078 | 2.0000 |
|
| HLE | STF-62247 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | SU11274 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | T0901317 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | TAF1_5496 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | TAK-715 | GDSC1 | 0.0400 | 20.0000 |
|
| HLE | Talazoparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Tamoxifen | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Tanespimycin | GDSC1,GDSC2,CCLE | 0.0010 | 8.0000 |
|
| HLE | TANK_1366 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | Taselisib | GDSC2 | 0.0040 | 10.0000 |
|
| HLE | Telomerase Inhibitor IX | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Temozolomide | GDSC1,GDSC2 | 0.0300 | 30.0000 |
|
| HLE | Temsirolimus | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| HLE | Teniposide | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | Tenovin-6 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Thapsigargin | GDSC1 | 0.0020 | 0.5120 |
|
| HLE | THR-101 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | THR-102 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | THR-103 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | THZ-2-102-1 | GDSC1 | 0.0098 | 2.5000 |
|
| HLE | THZ-2-49 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Tipifarnib | GDSC1 | 0.0625 | 16.0000 |
|
| HLE | Tivozanib | GDSC1 | 0.0005 | 0.1280 |
|
| HLE | TKI258 | CCLE | 0.0025 | 8.0000 |
|
| HLE | TL-1-85 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | TL-2-105 | GDSC1 | 0.0200 | 10.2400 |
|
| HLE | Topotecan | GDSC2,CCLE | 0.0025 | 8.0000 |
|
| HLE | Torin 2 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | TPCA-1 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Trametinib | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| HLE | Tretinoin | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Trichostatin A | GDSC1 | 0.0040 | 1.0240 |
|
| HLE | TTK_3146 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | Tubastatin A | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | TW 37 | GDSC1,GDSC2 | 0.0050 | 10.0000 |
|
| HLE | TWS119 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | Ulixertinib | GDSC2 | 0.0020 | 10.0000 |
|
| HLE | ULK1_4989 | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | UMI-77 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | UNC0379 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | UNC0638 | GDSC1,GDSC2 | 0.0050 | 40.0000 |
|
| HLE | UNC0642 | GDSC1 | 0.0020 | 0.5000 |
|
| HLE | UNC1215 | GDSC1 | 0.0039 | 1.0000 |
|
| HLE | Uprosertib | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | VE-822 | GDSC2 | 0.0050 | 5.0000 |
|
| HLE | VE821 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Veliparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Venetoclax | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | Venotoclax | GDSC1 | 0.0010 | 0.2560 |
|
| HLE | Vinblastine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| HLE | Vincristine | GDSC2 | 0.0030 | 3.0000 |
|
| HLE | Vinorelbine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| HLE | Vismodegib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | VNLG-124 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | Vorinostat | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Voxtalisib | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | VSP34_8731 | GDSC2 | 0.0300 | 30.0000 |
|
| HLE | VTP-A | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | VTP-B | GDSC2 | 0.0010 | 1.0000 |
|
| HLE | VX-11e | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | VX-702 | GDSC1 | 0.0078 | 2.0000 |
|
| HLE | Wee1 Inhibitor | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | WEHI-539 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | WHI-P97 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | WIKI4 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | Wnt-C59 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | WYE-125132 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | WZ3105 | GDSC1 | 0.0050 | 1.2800 |
|
| HLE | WZ4003 | GDSC2 | 0.0100 | 10.0000 |
|
| HLE | XAV939 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| HLE | XMD13-2 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | XMD14-99 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | XMD15-27 | GDSC1 | 0.0400 | 10.2400 |
|
| HLE | Y-39983 | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | YK-4-279 | GDSC1,GDSC2 | 0.0200 | 20.0000 |
|
| HLE | YM201636 | GDSC1 | 0.0200 | 5.1200 |
|
| HLE | ZD-6474 | CCLE | 0.0025 | 8.0000 |
|
| HLE | Zibotentan | GDSC1 | 0.0781 | 20.0000 |
|
| HLE | ZL049 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | ZL109 | GDSC1 | 0.0391 | 10.0000 |
|
| HLE | ZM447439 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| HLE | Zoledronate | GDSC2 | 0.0020 | 2.0000 |
|
| HLE | ZSTK474 | GDSC1 | 0.0200 | 10.2400 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Drugs with highest and lowest IC50
Drugs with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Drugs with highest and lowest IC90
Drugs with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Drugs with highest and lowest AUC
Drugs with highest and lowest AUC