Cell Line : H4

Cellosaurus Index : CVCL_1239
Cellosaurus ID : H4

CTRP2 Name , GDSC1 Name , GDSC2 Name : H4
CCLE Name : H4_CENTRAL_NERVOUS_SYSTEM

Cancer Type : central_nervous_system
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
H4 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
H4 123138 GDSC2 0.0010 1.0000
H4 123829 GDSC2 0.0030 3.0000
H4 150412 GDSC2 0.0030 3.0000
H4 5-azacytidine GDSC2 0.0200 20.0000
H4 5-Fluorouracil GDSC1,GDSC2 0.0200 32.0000
H4 50869 GDSC2 0.0030 3.0000
H4 615590 GDSC2 0.0030 3.0000
H4 630600 GDSC2 0.0030 3.0000
H4 667880 GDSC2 0.0030 3.0000
H4 720427 GDSC2 0.0030 3.0000
H4 729189 GDSC2 0.0030 3.0000
H4 741909 GDSC2 0.0010 1.0000
H4 743380 GDSC2 0.0010 1.0000
H4 765771 GDSC2 0.0030 3.0000
H4 776928 GDSC2 0.0300 30.0000
H4 965-D2 GDSC1 0.0391 10.0000
H4 993-D2 GDSC1 0.0391 10.0000
H4 A-366 GDSC2 0.0100 10.0000
H4 A-83-01 GDSC1 0.0781 20.0000
H4 ABT737 GDSC2 0.0100 10.0000
H4 Acetalax GDSC2 0.0300 30.0000
H4 ACY-1215 GDSC1 0.0781 20.0000
H4 AEW541 CCLE 0.0025 8.0000
H4 Afatinib GDSC1,GDSC2 0.0020 10.0000
H4 Afuresertib GDSC2 0.0100 10.0000
H4 AGI-5198 GDSC2 0.0100 10.0000
H4 AGI-6780 GDSC1,GDSC2 0.0020 10.0000
H4 AGK-2 GDSC2 0.0040 4.0000
H4 AICA Ribonucleotide GDSC1 7.8125 2000.0000
H4 AKT inhibitor VIII GDSC1 0.0100 10.2400
H4 Alectinib GDSC1 0.0200 5.1200
H4 Alisertib GDSC1,GDSC2 0.0020 10.0000
H4 Alpelisib GDSC2 0.0050 5.0000
H4 alpha-lipoic acid GDSC2 0.1211 121.0000
H4 AMG-319 GDSC2 0.0100 10.0000
H4 Amuvatinib GDSC1 0.0781 20.0000
H4 Apitolisib GDSC1 0.0781 20.0000
H4 AR-42 GDSC1 0.0200 5.1200
H4 Ara-G GDSC1 0.0781 20.0000
H4 ARRY-520 GDSC1 0.0010 0.2560
H4 AS601245 GDSC1 0.0312 8.0000
H4 AS605240 GDSC1 0.0781 20.0000
H4 ascorbate (vitamin C) GDSC2 2.0011 2000.0000
H4 AST-1306 GDSC1 0.0781 20.0000
H4 AT-7519 GDSC1 0.0400 10.2400
H4 AT13148 GDSC2 0.0100 10.0000
H4 AT7867 GDSC1 0.0781 20.0000
H4 Avagacestat GDSC1,GDSC2 0.0100 10.2400
H4 Axitinib GDSC1,GDSC2 0.0078 10.0000
H4 AZ20 GDSC1 0.0391 10.0000
H4 AZ6102 GDSC2 0.0100 10.0000
H4 AZ960 GDSC2 0.0100 10.0000
H4 AZD1208 GDSC1,GDSC2 0.0100 10.0000
H4 AZD1332 GDSC1,GDSC2 0.0100 10.0000
H4 AZD1480 GDSC1 0.0098 2.5000
H4 AZD2014 GDSC1,GDSC2 0.0100 10.0000
H4 AZD3514 GDSC1 0.0391 10.0000
H4 AZD3759 GDSC2 0.0010 1.0000
H4 AZD4547 GDSC1,GDSC2 0.0010 10.0000
H4 AZD4877 GDSC1 0.0002 0.0390
H4 AZD5153 GDSC2 0.0100 10.0000
H4 AZD5363 GDSC2 0.0100 10.0000
H4 AZD5438 GDSC1,GDSC2 0.0100 10.0000
H4 AZD5582 GDSC1,GDSC2 0.0100 10.0000
H4 AZD5991 GDSC2 0.0100 10.0000
H4 AZD6094 GDSC1 0.0098 2.5000
H4 AZD6482 GDSC1 0.0195 5.1200
H4 AZD6738 GDSC1,GDSC2 0.0100 10.0000
H4 AZD7762 GDSC1,GDSC2 0.0078 10.0000
H4 AZD7969 GDSC1 0.0391 10.0000
H4 AZD8055 GDSC1,GDSC2 0.0020 2.0000
H4 AZD8186 GDSC1,GDSC2 0.0098 10.0000
H4 AZD8835 GDSC1 0.0391 10.0000
H4 AZD8931 GDSC1 0.0391 10.0000
H4 BAM7 GDSC1 0.0781 20.0000
H4 BAY ACCi GDSC1 0.0391 10.0000
H4 BAY AKT1 GDSC1 0.0391 10.0000
H4 BAY-61-3606 GDSC1 0.0312 8.0000
H4 BAY-HDAC11_1 GDSC1 0.0391 10.0000
H4 BAY-HDAC11_2 GDSC1 0.0391 10.0000
H4 BAY-HDAC11_4 GDSC1 0.0391 10.0000
H4 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
H4 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
H4 BAY-MPS1 GDSC1 0.0117 3.0000
H4 BDF00022089a GDSC2 0.0050 5.0000
H4 BDILV000379a GDSC2 0.0050 5.0000
H4 BDOCA000347a GDSC2 0.0020 2.0000
H4 BDP-00009066 GDSC2 0.0100 10.0000
H4 Belinostat GDSC1 0.0781 20.0000
H4 BEN GDSC2 0.0300 30.0000
H4 Bexarotene GDSC1 0.0312 8.0000
H4 BI-2536 GDSC2 0.0010 1.0000
H4 BIBF-1120 GDSC1 0.0781 20.0000
H4 BIBR-1532 GDSC2 0.0100 10.0000
H4 Bicalutamide GDSC1 0.0040 10.0000
H4 BIX02189 GDSC1 0.0781 20.0000
H4 Bleomycin GDSC1,GDSC2 0.0020 64.0000
H4 Bleomycin (10 uM) GDSC1 0.0391 10.0000
H4 Bleomycin (50 uM) GDSC1,GDSC2 0.0400 50.0000
H4 BMS-345541 GDSC1,GDSC2 0.0100 16.0000
H4 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
H4 BMS-754807 GDSC1,GDSC2 0.0100 10.0000
H4 Bortezomib GDSC2 0.0000 0.0200
H4 Bosutinib GDSC1,GDSC2 0.0020 2.0000
H4 BPD-00008900 GDSC2 0.0100 10.0000
H4 BPTES GDSC1 0.0391 10.0000
H4 Brivanib, BMS-540215 GDSC1 0.0781 20.0000
H4 Bromosporine GDSC2 0.0020 2.0000
H4 Bryostatin 1 GDSC1 0.0000 0.0080
H4 Buparlisib GDSC2 0.0100 10.0000
H4 BX-912 GDSC1 0.0400 10.2400
H4 BX795 GDSC1 0.0195 5.0000
H4 C-75 GDSC1 0.0781 20.0000
H4 Cabozantinib GDSC1 0.0200 5.1200
H4 Camptothecin GDSC2 0.0001 0.1000
H4 CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
H4 Capivasertib GDSC1 0.1172 30.0000
H4 Carmustine GDSC2 0.0300 30.0000
H4 CAY10566 GDSC1 0.0100 2.5600
H4 CAY10603 GDSC1 0.0781 20.0000
H4 CCT-018159 GDSC1 0.0391 10.0000
H4 CCT007093 GDSC1,GDSC2 0.0100 10.0000
H4 CCT245232 GDSC1 0.0008 0.2000
H4 CCT245467 GDSC1 0.0008 0.2000
H4 CD532 GDSC1 0.0200 5.1200
H4 CDK9_5038 GDSC2 0.0030 3.0000
H4 CDK9_5576 GDSC2 0.0100 10.0000
H4 Cediranib GDSC2 0.0100 10.0000
H4 Cetuximab GDSC1 0.2570 65.8000
H4 CHIR-99021 GDSC1 0.0100 10.0000
H4 CI-1033 GDSC1 0.0781 20.0000
H4 CI-1040 GDSC1 0.0391 10.0000
H4 Cisplatin GDSC1,GDSC2 0.0040 10.0000
H4 CP466722 GDSC1 0.0625 16.0000
H4 CP724714 GDSC1 0.0400 10.2400
H4 CPI-613 GDSC1 1.0000 256.0000
H4 CPI-637 GDSC2 0.0100 10.0000
H4 Crizotinib GDSC2,CCLE 0.0010 10.0000
H4 CRT0105446 GDSC1 0.0391 10.0000
H4 CRT0105950 GDSC1 0.0391 10.0000
H4 CRT0160829 GDSC1 0.0781 20.0000
H4 CT7033-2 GDSC2 0.0100 10.0000
H4 CUDC-101 GDSC1 0.0200 5.1200
H4 CX-5461 GDSC1 0.0400 10.2400
H4 Cyclophosphamide GDSC2 0.0100 10.0000
H4 Cytarabine GDSC1,GDSC2 0.0020 2.0000
H4 CZC24832 GDSC2 0.0100 10.0000
H4 Dabrafenib GDSC1,GDSC2 0.0100 10.0000
H4 Dacarbazine GDSC2 0.0200 20.0000
H4 Dacinostat GDSC1 0.0040 1.0240
H4 Dactinomycin GDSC2 0.0000 0.8000
H4 Dactolisib GDSC1,GDSC2 0.0003 0.2500
H4 Daporinad GDSC1,GDSC2 0.0001 1.0000
H4 Dasatinib GDSC2 0.0010 2.0000
H4 Dihydrorotenone GDSC2 0.0010 1.0000
H4 Dinaciclib GDSC2 0.0010 1.0000
H4 DMOG GDSC1 15.6250 4000.0000
H4 Docetaxel GDSC1,GDSC2 0.0000 3.0000
H4 Doramapimod GDSC1,GDSC2 0.0100 10.0000
H4 Doxorubicin GDSC1 0.0040 5.0000
H4 Dyrk1b_0191 GDSC1 0.0391 10.0000
H4 eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
H4 Eg5_9814 GDSC2 0.0001 0.1000
H4 EHT-1864 GDSC1,GDSC2 0.0100 10.0000
H4 Elephantin GDSC2 0.0200 20.0000
H4 Elesclomol GDSC1 0.0008 0.2000
H4 Embelin GDSC1 0.1250 32.0000
H4 Entinostat GDSC2 0.0100 10.0000
H4 Entospletinib GDSC2 0.0100 10.0000
H4 Enzastaurin GDSC1 0.0781 20.0000
H4 EphB4_9721 GDSC1 0.0391 10.0000
H4 Epirubicin GDSC2 0.0010 1.0000
H4 Epothilone B GDSC1 0.0001 0.0320
H4 EPZ004777 GDSC2 0.0100 10.0000
H4 EPZ5676 GDSC2 0.0100 10.0000
H4 ERK_2440 GDSC2 0.0100 10.0000
H4 ERK_6604 GDSC2 0.0100 10.0000
H4 Erlotinib GDSC2,CCLE 0.0020 8.0000
H4 Etoposide GDSC1 0.0625 16.0000
H4 ETP-45835 GDSC1 0.0781 20.0000
H4 Fedratinib GDSC1 0.0400 10.2400
H4 FEN1_3940 GDSC1 0.0391 10.0000
H4 FGFR_0939 GDSC1 0.0098 2.5000
H4 FGFR_3831 GDSC1 0.0391 10.0000
H4 FH535 GDSC1 0.1250 32.0000
H4 Flavopiridol GDSC1 0.0100 2.5600
H4 Fludarabine GDSC2 0.0200 20.0000
H4 FMK GDSC1 0.0781 20.0000
H4 Foretinib GDSC1,GDSC2 0.0100 10.0000
H4 FR-180204 GDSC1 0.0781 20.0000
H4 FS106 GDSC1 0.0391 10.0000
H4 FS112 GDSC1 0.0195 5.0000
H4 FTI-277 GDSC1 0.0040 1.0240
H4 FTY-720 GDSC1 0.0781 20.0000
H4 Fulvestrant GDSC1,GDSC2 0.0010 10.0000
H4 FY012 GDSC1 0.0391 10.0000
H4 FY026 GDSC1 0.0391 10.0000
H4 FY069 GDSC1 0.0391 10.0000
H4 Gallibiscoquinazole GDSC2 0.0010 1.0000
H4 GDC0810 GDSC2 0.0100 10.0000
H4 Gefitinib GDSC1,GDSC2 0.0020 2.0000
H4 Gemcitabine GDSC1,GDSC2 0.0001 10.0000
H4 Genentech Cpd 10 GDSC1 0.0400 10.2400
H4 glutathione GDSC2 0.6403 640.0000
H4 GNE-317 GDSC2 0.0100 10.0000
H4 GSK-J4 GDSC1 0.1172 30.0000
H4 GSK-LSD1 GDSC2 0.0010 1.0000
H4 GSK-LSD1-2HCl GDSC2 0.0010 1.0000
H4 GSK1059615 GDSC1 0.0781 20.0000
H4 GSK1070916 GDSC1 0.0100 2.5600
H4 GSK1904529A GDSC1,GDSC2 0.0040 10.0000
H4 GSK2110183B GDSC2 0.0030 3.0000
H4 GSK2256098C GDSC2 0.0030 3.0000
H4 GSK2276186C GDSC2 0.0100 10.0000
H4 GSK2578215A GDSC2 0.0100 10.0000
H4 GSK2606414 GDSC2 0.0100 10.0000
H4 GSK269962A GDSC1 0.0195 5.0000
H4 GSK2801 GDSC2 0.0100 10.0000
H4 GSK2830371 GDSC2 0.0100 10.0000
H4 GSK2830371A GDSC2 0.0030 10.0000
H4 GSK3337463A GDSC2 0.0100 10.0000
H4 GSK343 GDSC2 0.0010 10.0000
H4 GSK429286A GDSC1 0.0781 20.0000
H4 GSK591 GDSC2 0.0100 10.0000
H4 GSK626616AC GDSC2 0.0001 0.1000
H4 GSK650394 GDSC1 0.0625 16.0000
H4 GSK690693 GDSC1 0.0400 10.2400
H4 GW-2580 GDSC1 0.0781 20.0000
H4 GW441756 GDSC1,GDSC2 0.0020 2.0000
H4 HG6-64-1 GDSC1 0.0200 5.1200
H4 HKMTI-1-005 GDSC2 0.0100 10.0000
H4 I-BET-762 GDSC1,GDSC2 0.0100 20.0000
H4 I-BET151 GDSC1 0.0391 10.0000
H4 I-BRD9 GDSC2 0.0100 10.0000
H4 I-CBP112 GDSC1 0.0391 10.0000
H4 IAP_5620 GDSC1,GDSC2 0.0100 10.0000
H4 IAP_7638 GDSC1 0.0391 10.0000
H4 Ibrutinib GDSC2 0.0100 10.0000
H4 IC-87114 GDSC1 0.0781 20.0000
H4 ICL-SIRT078 GDSC2 0.0100 10.0000
H4 ICL1100013 GDSC1 0.0781 20.0000
H4 Idelalisib GDSC1 0.0781 20.0000
H4 IGF1R_3801 GDSC2 0.0100 10.0000
H4 IGFR_3801 GDSC1 0.0391 10.0000
H4 IMD-0354 GDSC1 0.0781 20.0000
H4 IOX2 GDSC1 0.0004 0.1000
H4 IPA-3 GDSC1 0.1250 32.0000
H4 Ipatasertib GDSC2 0.0100 10.0000
H4 IRAK4_4710 GDSC2 0.0100 10.0000
H4 Irinotecan GDSC2 0.0050 10.0000
H4 Ispinesib Mesylate GDSC1 0.0005 0.1280
H4 IWP-2 GDSC2 0.0010 1.0000
H4 JAK_8517 GDSC2 0.0100 10.0000
H4 JAK1_3715 GDSC1 0.0391 10.0000
H4 JAK1_8709 GDSC2 0.0100 10.0000
H4 JAK3_7406 GDSC1 0.0391 10.0000
H4 JNJ38877605 GDSC1 0.0781 20.0000
H4 JNK Inhibitor VIII GDSC1,GDSC2 0.0100 10.0000
H4 JNK-9L GDSC1 0.0200 5.1200
H4 JQ1 GDSC1,GDSC2 0.0039 10.0000
H4 JQ12 GDSC1 0.0200 5.1200
H4 JW-7-24-1 GDSC1 0.0400 10.2400
H4 kb NB 142-70 GDSC1 0.0781 20.0000
H4 KIN001-042 GDSC1 0.0400 10.2400
H4 KIN001-236 GDSC1 0.0400 10.2400
H4 KIN001-244 GDSC1 0.0781 20.0000
H4 KIN001-260 GDSC1 0.0781 20.0000
H4 KIN001-266 GDSC1 0.0781 20.0000
H4 KIN001-270 GDSC1 0.0781 20.0000
H4 Kobe2602 GDSC1 0.0781 20.0000
H4 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
H4 KU-55933 GDSC1,GDSC2 0.0100 10.0000
H4 KU-60019 GDSC1 0.0391 10.0000
H4 L-685458 CCLE 0.0025 8.0000
H4 L-Oxonoreleagnine GDSC2 0.0030 3.0000
H4 Lapatinib GDSC2,CCLE 0.0025 10.0000
H4 LBW242 CCLE 0.0025 8.0000
H4 LCL161 GDSC1,GDSC2 0.0100 10.0000
H4 LDN-193189 GDSC1 0.0400 10.2400
H4 Leflunomide GDSC2 0.1001 100.0000
H4 Lenalidomide GDSC1,GDSC2 0.0100 10.0000
H4 Lestaurtinib GDSC1,GDSC2 0.0020 2.0000
H4 LFM-A13 GDSC1 0.0625 16.0000
H4 LGK974 GDSC1,GDSC2 0.0050 10.0000
H4 LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
H4 Linifanib GDSC1 0.0040 1.0240
H4 Linsitinib GDSC1,GDSC2 0.0025 10.0000
H4 LJI308 GDSC2 0.0100 10.0000
H4 LMB_AB1 GDSC2 0.0100 10.0000
H4 LMB_AB2 GDSC2 0.0100 10.0000
H4 LMB_AB3 GDSC2 0.0100 10.0000
H4 LMP744 GDSC2 0.0030 3.0000
H4 Luminespib GDSC1,GDSC2 0.0003 1.0000
H4 LY2109761 GDSC2 0.0100 10.0000
H4 Masitinib GDSC1 0.0781 20.0000
H4 MCT1_6447 GDSC1 0.0391 10.0000
H4 MCT4_1422 GDSC1 0.0391 10.0000
H4 MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
H4 Methotrexate GDSC1,GDSC2 0.0008 1.0000
H4 MG-132 GDSC2 0.0156 4.0000
H4 Midostaurin GDSC1 0.0020 0.5120
H4 MIM1 GDSC1,GDSC2 0.0100 40.0000
H4 MIRA-1 GDSC2 0.0100 10.0000
H4 Mirin GDSC1,GDSC2 0.1001 100.0000
H4 Mitomycin-C GDSC1 0.0625 16.0000
H4 Mitoxantrone GDSC2 0.0030 3.0000
H4 MK-1775 GDSC2 0.0100 10.0000
H4 MK-2206 GDSC1,GDSC2 0.0100 10.0000
H4 MK-8776 GDSC2 0.0050 5.0000
H4 ML323 GDSC2 0.0200 20.0000
H4 MN-64 GDSC2 0.0100 10.0000
H4 Motesanib GDSC1,GDSC2 0.0078 10.0000
H4 MPS-1-IN-1 GDSC1 0.0781 20.0000
H4 Mycophenolic acid GDSC2 0.0100 10.0000
H4 N-acetyl cysteine GDSC2 2.0011 2000.0000
H4 N22899-6-C1 GDSC1 0.0391 10.0000
H4 N23918-95-7 GDSC1 0.0391 10.0000
H4 N24798-49-A1 GDSC1 0.0391 10.0000
H4 N25720-51-A1 GDSC2 0.0100 10.0000
H4 N27922-53-1 GDSC2 0.0100 10.0000
H4 N29087-69-1 GDSC2 0.0100 10.0000
H4 N30652-18-1 GDSC2 0.0100 10.0000
H4 Navitoclax GDSC1,GDSC2 0.0020 10.0000
H4 Nelarabine GDSC2 0.0200 20.0000
H4 NG-25 GDSC1 0.0400 10.2400
H4 Nilotinib GDSC1,GDSC2,CCLE 0.0020 8.0000
H4 Niraparib GDSC2 0.0100 10.0000
H4 NPK76-II-72-1 GDSC1 0.0400 10.2400
H4 NSC-207895 GDSC1 0.0781 20.0000
H4 NSC-87877 GDSC1 0.0625 16.0000
H4 NSC319726 GDSC1 0.0010 0.2560
H4 NU7441 GDSC1,GDSC2 0.0078 10.0000
H4 Nutlin-3a GDSC1,GDSC2,CCLE 0.0025 10.0000
H4 NVP-ADW742 GDSC2 0.0100 10.0000
H4 NVP-BHG712 GDSC1 0.0400 10.2400
H4 NVP-TAE684 CCLE 0.0025 8.0000
H4 Obatoclax Mesylate GDSC1,GDSC2 0.0100 16.0000
H4 OF-1 GDSC2 0.0100 10.0000
H4 Olaparib GDSC1,GDSC2 0.0100 10.0000
H4 Omipalisib GDSC1 0.0005 0.1280
H4 OSI-027 GDSC1,GDSC2 0.0040 20.0000
H4 OSI-930 GDSC1 0.0400 10.2400
H4 Osimertinib GDSC2 0.0010 1.0000
H4 OSU-03012 GDSC1 0.0625 16.0000
H4 OTX015 GDSC2 0.0100 10.0000
H4 Oxaliplatin GDSC2 0.0100 20.0000
H4 P22077 GDSC2 0.0100 10.0000
H4 PAC-1 GDSC1 0.0100 2.5600
H4 Paclitaxel GDSC2,CCLE 0.0000 8.0000
H4 PAK_5339 GDSC2 0.0300 30.0000
H4 Palbociclib GDSC1,GDSC2,CCLE 0.0025 10.0000
H4 Panobinostat GDSC1,CCLE 0.0025 8.0000
H4 PARP_0108 GDSC1 0.0098 2.5000
H4 PARP_9482 GDSC1 0.0098 2.5000
H4 PARP_9495 GDSC1 0.0098 2.5000
H4 Pazopanib GDSC1 0.0312 8.0000
H4 PBD-288 GDSC2 0.0050 5.0000
H4 PCI-34051 GDSC2 0.0100 10.0000
H4 PD0325901 GDSC1,GDSC2,CCLE 0.0003 8.0000
H4 PD173074 GDSC1,GDSC2 0.0020 10.0000
H4 Pelitinib GDSC1 0.0098 2.5000
H4 Pemetrexed GDSC1 0.0100 2.5600
H4 Pevonedistat GDSC1,GDSC2 0.0039 10.0000
H4 PF-00299804 GDSC1 0.0781 20.0000
H4 PF-4708671 GDSC1 0.0391 10.0000
H4 PF-562271 GDSC1 0.0100 2.5600
H4 PFI-1 GDSC1,GDSC2 0.0100 10.0000
H4 PFI3 GDSC1,GDSC2 0.0100 10.0000
H4 PHA-665752 CCLE 0.0025 8.0000
H4 PHA-793887 GDSC1 0.0400 10.2400
H4 Phenformin GDSC1 15.6250 4000.0000
H4 PI-103 GDSC1 0.0400 10.2400
H4 PI3Ka_4409 GDSC1 0.0391 10.0000
H4 Picolinici-acid GDSC2 0.0100 10.0000
H4 Pictilisib GDSC1,GDSC2 0.0040 10.0000
H4 PIK-93 GDSC1 0.0781 20.0000
H4 Pilaralisib GDSC1 0.0781 20.0000
H4 Piperlongumine GDSC1 0.0391 10.0000
H4 PLK_6522 GDSC1 0.0024 0.6250
H4 PLX-4720 GDSC1,GDSC2,CCLE 0.0025 10.0000
H4 Podophyllotoxin bromide GDSC2 0.0010 1.0000
H4 POMHEX GDSC2 0.0100 10.0000
H4 Ponatinib GDSC1 0.0020 0.5120
H4 PRIMA-1MET GDSC2 0.0300 30.0000
H4 PRT062607 GDSC2 0.0100 10.0000
H4 Pyridostatin GDSC2 0.0100 10.0000
H4 QL-X-138 GDSC1 0.0400 10.2400
H4 QL-XI-92 GDSC1 0.0400 10.2400
H4 QL-XII-47 GDSC1 0.0400 10.2400
H4 QS11 GDSC1 0.0400 10.2400
H4 Quizartinib GDSC1 0.0040 1.0240
H4 RAF_9304 GDSC1 0.0391 10.0000
H4 RAF265 CCLE 0.0025 8.0000
H4 Rapamycin GDSC2 0.0000 0.0200
H4 Refametinib GDSC1,GDSC2 0.0100 10.0000
H4 Ribociclib GDSC2 0.0020 2.0000
H4 RO-3306 GDSC1,GDSC2 0.0100 10.0000
H4 Romidepsin GDSC2 0.0000 0.0100
H4 rTRAIL GDSC1 0.0004 0.1000
H4 RU-SKI 43 GDSC1 0.0781 20.0000
H4 Rucaparib GDSC1,GDSC2 0.0050 5.0000
H4 Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
H4 RVX-208 GDSC2 0.0100 10.0000
H4 Sabutoclax GDSC2 0.0100 10.0000
H4 Sapitinib GDSC2 0.0050 10.0000
H4 Saracatinib CCLE 0.0025 8.0000
H4 Savolitinib GDSC2 0.0010 1.0000
H4 SB216763 GDSC1,GDSC2 0.0100 10.0000
H4 SB505124 GDSC1 0.0391 20.0000
H4 SB52334 GDSC1 0.0781 20.0000
H4 SB590885 GDSC1,GDSC2 0.0050 5.0000
H4 SCH772984 GDSC2 0.0050 5.0000
H4 Schweinfurthin A GDSC2 0.0010 1.0000
H4 Selisistat GDSC1 0.0781 20.0000
H4 Selumetinib GDSC1,GDSC2,CCLE 0.0025 10.0000
H4 Sepantronium bromide GDSC1,GDSC2 0.0100 10.0000
H4 Serdemetan GDSC1,GDSC2 0.0100 10.0000
H4 SGC-CBP30 GDSC2 0.0050 5.0000
H4 SGC0946 GDSC1,GDSC2 0.0005 0.5000
H4 Shikonin GDSC1 0.0625 16.0000
H4 Sinularin GDSC2 0.0030 3.0000
H4 SL0101 GDSC1 0.0391 10.0000
H4 SN-38 GDSC1,GDSC2 0.0000 0.1000
H4 SNX-2112 GDSC1 0.0100 2.5600
H4 Sorafenib GDSC2,CCLE 0.0025 10.0000
H4 Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
H4 Staurosporine GDSC2 0.0078 2.0000
H4 STF-62247 GDSC1 0.0400 10.2400
H4 SU11274 GDSC1 0.0400 10.2400
H4 T0901317 GDSC1 0.0400 10.2400
H4 TAF1_5496 GDSC2 0.0100 10.0000
H4 TAK-715 GDSC1 0.0781 20.0000
H4 Talazoparib GDSC1,GDSC2 0.0100 10.0000
H4 Tamoxifen GDSC1,GDSC2 0.0100 10.0000
H4 Tanespimycin GDSC1,GDSC2,CCLE 0.0010 8.0000
H4 TANK_1366 GDSC1 0.0098 2.5000
H4 Taselisib GDSC2 0.0040 10.0000
H4 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
H4 Temozolomide GDSC1,GDSC2 0.0300 30.0000
H4 Temsirolimus GDSC1,GDSC2 0.0008 1.0000
H4 Teniposide GDSC2 0.0030 3.0000
H4 Tenovin-6 GDSC1 0.0781 20.0000
H4 Thapsigargin GDSC1 0.0020 0.5120
H4 THR-101 GDSC2 0.0100 10.0000
H4 THR-102 GDSC2 0.0100 10.0000
H4 THR-103 GDSC2 0.0100 10.0000
H4 THZ-2-102-1 GDSC1 0.0098 2.5000
H4 THZ-2-49 GDSC1 0.0781 20.0000
H4 Tipifarnib GDSC1 0.0625 16.0000
H4 Tivozanib GDSC1 0.0005 0.1280
H4 TKI258 CCLE 0.0025 8.0000
H4 TL-1-85 GDSC1 0.0400 10.2400
H4 TL-2-105 GDSC1 0.0400 10.2400
H4 Topotecan GDSC2,CCLE 0.0025 8.0000
H4 Torin 2 GDSC1 0.0781 20.0000
H4 TPCA-1 GDSC1 0.0781 20.0000
H4 Trametinib GDSC1,GDSC2 0.0010 1.0000
H4 Tretinoin GDSC1 0.0391 10.0000
H4 Trichostatin A GDSC1 0.0040 1.0240
H4 TTK_3146 GDSC1 0.0391 10.0000
H4 Tubastatin A GDSC1 0.0781 20.0000
H4 TW 37 GDSC1,GDSC2 0.0050 5.0000
H4 TWS119 GDSC1 0.0781 20.0000
H4 Ulixertinib GDSC2 0.0020 10.0000
H4 ULK1_4989 GDSC2 0.0300 30.0000
H4 UMI-77 GDSC2 0.0100 10.0000
H4 UNC0379 GDSC2 0.0100 10.0000
H4 UNC0638 GDSC1,GDSC2 0.0050 40.0000
H4 UNC0642 GDSC1 0.0020 0.5000
H4 UNC1215 GDSC1 0.0039 1.0000
H4 Uprosertib GDSC2 0.0100 10.0000
H4 VE-822 GDSC2 0.0050 5.0000
H4 VE821 GDSC2 0.0100 10.0000
H4 Veliparib GDSC1,GDSC2 0.0100 10.0000
H4 Venetoclax GDSC2 0.0010 1.0000
H4 Venotoclax GDSC1 0.0010 0.2560
H4 Vinblastine GDSC1,GDSC2 0.0001 0.1000
H4 Vincristine GDSC2 0.0030 3.0000
H4 Vinorelbine GDSC1,GDSC2 0.0001 0.1000
H4 Vismodegib GDSC1,GDSC2 0.0100 10.0000
H4 VNLG-124 GDSC1 0.0200 5.1200
H4 Vorinostat GDSC1,GDSC2 0.0100 10.0000
H4 Voxtalisib GDSC1 0.0781 20.0000
H4 VSP34_8731 GDSC2 0.0300 30.0000
H4 VTP-A GDSC2 0.0010 1.0000
H4 VTP-B GDSC2 0.0010 1.0000
H4 VX-11e GDSC1,GDSC2 0.0100 10.0000
H4 VX-702 GDSC1 0.0078 2.0000
H4 Wee1 Inhibitor GDSC1,GDSC2 0.0078 10.0000
H4 WEHI-539 GDSC2 0.0100 10.0000
H4 WHI-P97 GDSC1 0.0400 10.2400
H4 WIKI4 GDSC2 0.0100 10.0000
H4 Wnt-C59 GDSC1,GDSC2 0.0100 10.0000
H4 WYE-125132 GDSC1 0.0400 10.2400
H4 WZ3105 GDSC1 0.0050 1.2800
H4 WZ4003 GDSC2 0.0100 10.0000
H4 XAV939 GDSC1,GDSC2 0.0100 10.0000
H4 XMD13-2 GDSC1 0.0400 10.2400
H4 XMD14-99 GDSC1 0.0400 10.2400
H4 XMD15-27 GDSC1 0.0400 10.2400
H4 Y-39983 GDSC1 0.0781 20.0000
H4 YK-4-279 GDSC1,GDSC2 0.0200 20.0000
H4 YM201636 GDSC1 0.0200 5.1200
H4 ZD-6474 CCLE 0.0025 8.0000
H4 Zibotentan GDSC1 0.0781 20.0000
H4 ZL049 GDSC1 0.0391 10.0000
H4 ZL109 GDSC1 0.0391 10.0000
H4 ZM447439 GDSC1,GDSC2 0.0100 10.0000
H4 Zoledronate GDSC2 0.0020 2.0000
H4 ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC