Cell Line : HS445

Cellosaurus Index : CVCL_0761
Cellosaurus ID : HS445

GDSC1 Name , GDSC2 Name : Hs-445
CCLE Name : HS445_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
HS445 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
HS445 123138 GDSC2 0.0010 1.0000
HS445 123829 GDSC2 0.0030 3.0000
HS445 150412 GDSC2 0.0030 3.0000
HS445 5-azacytidine GDSC2 0.0200 20.0000
HS445 5-Fluorouracil GDSC1,GDSC2 0.0200 32.0000
HS445 50869 GDSC2 0.0030 3.0000
HS445 615590 GDSC2 0.0030 3.0000
HS445 630600 GDSC2 0.0030 3.0000
HS445 667880 GDSC2 0.0030 3.0000
HS445 720427 GDSC2 0.0030 3.0000
HS445 729189 GDSC2 0.0030 3.0000
HS445 741909 GDSC2 0.0010 1.0000
HS445 743380 GDSC2 0.0010 1.0000
HS445 765771 GDSC2 0.0030 3.0000
HS445 776928 GDSC2 0.0300 30.0000
HS445 965-D2 GDSC1 0.0391 10.0000
HS445 993-D2 GDSC1 0.0391 10.0000
HS445 A-366 GDSC2 0.0100 10.0000
HS445 A-443654 GDSC1 0.0040 1.0240
HS445 A-770041 GDSC1 0.0200 5.1200
HS445 A-83-01 GDSC1 0.0781 20.0000
HS445 ABT737 GDSC2 0.0100 10.0000
HS445 Acetalax GDSC2 0.0300 30.0000
HS445 ACY-1215 GDSC1 0.0781 20.0000
HS445 Afatinib GDSC1,GDSC2 0.0020 10.0000
HS445 Afuresertib GDSC2 0.0100 10.0000
HS445 AGI-5198 GDSC2 0.0100 10.0000
HS445 AGI-6780 GDSC1,GDSC2 0.0020 10.0000
HS445 AGK-2 GDSC2 0.0040 4.0000
HS445 AKT inhibitor VIII GDSC1 0.0100 10.2400
HS445 Alectinib GDSC1 0.0200 5.1200
HS445 Alisertib GDSC1,GDSC2 0.0020 10.0000
HS445 Alpelisib GDSC2 0.0050 5.0000
HS445 alpha-lipoic acid GDSC2 0.1211 121.0000
HS445 AMG-319 GDSC2 0.0100 10.0000
HS445 Amuvatinib GDSC1 0.0781 20.0000
HS445 Apitolisib GDSC1 0.0781 20.0000
HS445 AR-42 GDSC1 0.0200 5.1200
HS445 Ara-G GDSC1 0.0781 20.0000
HS445 ARRY-520 GDSC1 0.0010 0.2560
HS445 AS601245 GDSC1 0.0312 8.0000
HS445 AS605240 GDSC1 0.0781 20.0000
HS445 ascorbate (vitamin C) GDSC2 2.0011 2000.0000
HS445 AST-1306 GDSC1 0.0781 20.0000
HS445 AT-7519 GDSC1 0.0400 10.2400
HS445 AT13148 GDSC2 0.0100 10.0000
HS445 AT7867 GDSC1 0.0781 20.0000
HS445 Avagacestat GDSC1,GDSC2 0.0100 10.2400
HS445 Axitinib GDSC2 0.0100 10.0000
HS445 AZ6102 GDSC2 0.0100 10.0000
HS445 AZ628 GDSC1 0.0156 4.0000
HS445 AZ960 GDSC2 0.0100 10.0000
HS445 AZD1208 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD1332 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD1480 GDSC1 0.0098 2.5000
HS445 AZD2014 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD3514 GDSC1 0.0391 10.0000
HS445 AZD3759 GDSC2 0.0010 1.0000
HS445 AZD4547 GDSC1,GDSC2 0.0010 1.0000
HS445 AZD4877 GDSC1 0.0002 0.0390
HS445 AZD5153 GDSC2 0.0100 10.0000
HS445 AZD5363 GDSC2 0.0100 10.0000
HS445 AZD5438 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD5582 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD5991 GDSC2 0.0100 10.0000
HS445 AZD6094 GDSC1 0.0098 2.5000
HS445 AZD6482 GDSC1 0.0200 5.1200
HS445 AZD6738 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD7762 GDSC1,GDSC2 0.0100 10.0000
HS445 AZD7969 GDSC1 0.0391 10.0000
HS445 AZD8055 GDSC2 0.0020 2.0000
HS445 AZD8186 GDSC1,GDSC2 0.0098 10.0000
HS445 AZD8835 GDSC1 0.0391 10.0000
HS445 AZD8931 GDSC1 0.0391 10.0000
HS445 BAM7 GDSC1 0.0781 20.0000
HS445 BAY ACCi GDSC1 0.0391 10.0000
HS445 BAY AKT1 GDSC1 0.0391 10.0000
HS445 BAY-61-3606 GDSC1 0.0312 8.0000
HS445 BAY-HDAC11_1 GDSC1 0.0391 10.0000
HS445 BAY-HDAC11_2 GDSC1 0.0391 10.0000
HS445 BAY-HDAC11_4 GDSC1 0.0391 10.0000
HS445 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
HS445 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
HS445 BAY-MPS1 GDSC1 0.0117 3.0000
HS445 BDF00022089a GDSC2 0.0050 5.0000
HS445 BDILV000379a GDSC2 0.0050 5.0000
HS445 BDOCA000347a GDSC2 0.0020 2.0000
HS445 BDP-00009066 GDSC2 0.0100 10.0000
HS445 Belinostat GDSC1 0.0781 20.0000
HS445 BEN GDSC2 0.0300 30.0000
HS445 Bexarotene GDSC1 0.0312 8.0000
HS445 BI-2536 GDSC1,GDSC2 0.0010 1.0000
HS445 BIBF-1120 GDSC1 0.0781 20.0000
HS445 BIBR-1532 GDSC2 0.0100 10.0000
HS445 Bicalutamide GDSC1 0.0040 10.0000
HS445 BIX02189 GDSC1 0.0781 20.0000
HS445 Bleomycin GDSC1,GDSC2 0.0020 64.0000
HS445 Bleomycin (10 uM) GDSC1 0.0391 10.0000
HS445 Bleomycin (50 uM) GDSC1,GDSC2 0.0400 50.0000
HS445 BMS-345541 GDSC1,GDSC2 0.0100 16.0000
HS445 BMS-509744 GDSC1 0.0400 10.2400
HS445 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
HS445 BMS-754807 GDSC1,GDSC2 0.0100 10.0000
HS445 Bortezomib GDSC1,GDSC2 0.0000 0.0200
HS445 Bosutinib GDSC2 0.0020 2.0000
HS445 BPD-00008900 GDSC2 0.0100 10.0000
HS445 BPTES GDSC1 0.0391 10.0000
HS445 Brivanib, BMS-540215 GDSC1 0.0781 20.0000
HS445 Bromosporine GDSC2 0.0020 2.0000
HS445 Bryostatin 1 GDSC1 0.0000 0.0080
HS445 Buparlisib GDSC2 0.0100 10.0000
HS445 BX-912 GDSC1 0.0400 10.2400
HS445 C-75 GDSC1 0.0781 20.0000
HS445 Cabozantinib GDSC1 0.0200 5.1200
HS445 Camptothecin GDSC2 0.0001 0.1000
HS445 CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
HS445 Carmustine GDSC2 0.0300 30.0000
HS445 CAY10566 GDSC1 0.0100 2.5600
HS445 CAY10603 GDSC1 0.0781 20.0000
HS445 CCT007093 GDSC2 0.0100 10.0000
HS445 CD532 GDSC1 0.0200 5.1200
HS445 CDK9_5038 GDSC2 0.0030 3.0000
HS445 CDK9_5576 GDSC2 0.0100 10.0000
HS445 Cediranib GDSC2 0.0100 10.0000
HS445 Cetuximab GDSC1 0.2570 65.8000
HS445 CGP-082996 GDSC1 0.0200 5.1200
HS445 CGP-60474 GDSC1 0.0010 0.2560
HS445 CHIR-99021 GDSC1 0.0100 10.0000
HS445 CI-1033 GDSC1 0.0781 20.0000
HS445 Cisplatin GDSC1,GDSC2 0.0040 6.0000
HS445 CMK GDSC1 0.0156 4.0000
HS445 CP466722 GDSC1 0.0625 16.0000
HS445 CP724714 GDSC1 0.0400 10.2400
HS445 CPI-613 GDSC1 1.0000 256.0000
HS445 CPI-637 GDSC2 0.0100 10.0000
HS445 Crizotinib GDSC1,GDSC2 0.0010 10.0000
HS445 CT7033-2 GDSC2 0.0100 10.0000
HS445 CUDC-101 GDSC1 0.0200 5.1200
HS445 CX-5461 GDSC1 0.0400 10.2400
HS445 Cyclopamine GDSC1 0.0625 16.0000
HS445 Cyclophosphamide GDSC2 0.0100 10.0000
HS445 Cytarabine GDSC2 0.0020 2.0000
HS445 CZC24832 GDSC2 0.0100 10.0000
HS445 Dabrafenib GDSC1,GDSC2 0.0100 10.0000
HS445 Dacarbazine GDSC2 0.0200 20.0000
HS445 Dacinostat GDSC1 0.0040 1.0240
HS445 Dactinomycin GDSC2 0.0000 0.8000
HS445 Dactolisib GDSC2 0.0003 0.2500
HS445 Daporinad GDSC1 0.0039 1.0000
HS445 Dasatinib GDSC1,GDSC2 0.0010 2.0000
HS445 Dihydrorotenone GDSC2 0.0010 1.0000
HS445 Dinaciclib GDSC2 0.0010 1.0000
HS445 DMOG GDSC1 15.6250 4000.0000
HS445 Docetaxel GDSC2 0.0000 3.0000
HS445 Doramapimod GDSC2 0.0100 10.0000
HS445 Doxorubicin GDSC1 0.0040 5.0000
HS445 Dyrk1b_0191 GDSC1 0.0391 10.0000
HS445 eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
HS445 Eg5_9814 GDSC2 0.0001 0.1000
HS445 EHT-1864 GDSC2 0.0100 10.0000
HS445 Elephantin GDSC2 0.0200 20.0000
HS445 Embelin GDSC1 0.1250 32.0000
HS445 Entinostat GDSC1,GDSC2 0.0100 10.0000
HS445 Entospletinib GDSC2 0.0100 10.0000
HS445 Enzastaurin GDSC1 0.0781 20.0000
HS445 EphB4_9721 GDSC1 0.0391 10.0000
HS445 Epirubicin GDSC2 0.0010 1.0000
HS445 Epothilone B GDSC1 0.0001 0.0320
HS445 EPZ004777 GDSC2 0.0100 10.0000
HS445 EPZ5676 GDSC2 0.0100 10.0000
HS445 ERK_2440 GDSC2 0.0100 10.0000
HS445 ERK_6604 GDSC2 0.0100 10.0000
HS445 Erlotinib GDSC1,GDSC2 0.0020 2.0000
HS445 Etoposide GDSC1 0.0625 16.0000
HS445 ETP-45835 GDSC1 0.0781 20.0000
HS445 Fedratinib GDSC1 0.0400 10.2400
HS445 FEN1_3940 GDSC1 0.0391 10.0000
HS445 FGFR_0939 GDSC1 0.0098 2.5000
HS445 FGFR_3831 GDSC1 0.0391 10.0000
HS445 FH535 GDSC1 0.1250 32.0000
HS445 Flavopiridol GDSC1 0.0100 2.5600
HS445 Fludarabine GDSC2 0.0200 20.0000
HS445 FMK GDSC1 0.0781 20.0000
HS445 Foretinib GDSC1,GDSC2 0.0100 10.0000
HS445 FR-180204 GDSC1 0.0781 20.0000
HS445 FTI-277 GDSC1 0.0040 1.0240
HS445 FTY-720 GDSC1 0.0781 20.0000
HS445 Fulvestrant GDSC1,GDSC2 0.0010 10.0000
HS445 FY012 GDSC1 0.0391 10.0000
HS445 FY026 GDSC1 0.0391 10.0000
HS445 FY069 GDSC1 0.0391 10.0000
HS445 Gallibiscoquinazole GDSC2 0.0010 1.0000
HS445 GDC0810 GDSC2 0.0100 10.0000
HS445 Gefitinib GDSC2 0.0020 2.0000
HS445 Gemcitabine GDSC1,GDSC2 0.0001 10.0000
HS445 Genentech Cpd 10 GDSC1 0.0400 10.2400
HS445 glutathione GDSC2 0.6403 640.0000
HS445 GNE-317 GDSC2 0.0100 10.0000
HS445 GNF-2 GDSC1 0.0050 1.2800
HS445 GSK-J4 GDSC1 0.1172 30.0000
HS445 GSK-LSD1 GDSC2 0.0010 1.0000
HS445 GSK-LSD1-2HCl GDSC2 0.0010 1.0000
HS445 GSK1059615 GDSC1 0.0781 20.0000
HS445 GSK1070916 GDSC1 0.0100 2.5600
HS445 GSK1904529A GDSC1,GDSC2 0.0040 10.0000
HS445 GSK2110183B GDSC2 0.0030 3.0000
HS445 GSK2256098C GDSC2 0.0030 3.0000
HS445 GSK2276186C GDSC2 0.0100 10.0000
HS445 GSK2578215A GDSC2 0.0100 10.0000
HS445 GSK2606414 GDSC2 0.0100 10.0000
HS445 GSK269962A GDSC1 0.0098 5.0000
HS445 GSK2801 GDSC2 0.0100 10.0000
HS445 GSK2830371 GDSC2 0.0100 10.0000
HS445 GSK2830371A GDSC2 0.0030 10.0000
HS445 GSK319347A GDSC1 0.0195 5.0000
HS445 GSK3337463A GDSC2 0.0100 10.0000
HS445 GSK343 GDSC2 0.0010 10.0000
HS445 GSK429286A GDSC1 0.0781 20.0000
HS445 GSK591 GDSC2 0.0100 10.0000
HS445 GSK626616AC GDSC2 0.0001 0.1000
HS445 GSK650394 GDSC1 0.0625 16.0000
HS445 GSK690693 GDSC1 0.0400 10.2400
HS445 GW-2580 GDSC1 0.0781 20.0000
HS445 GW441756 GDSC2 0.0020 2.0000
HS445 GW843682X GDSC1 0.0010 0.2560
HS445 HG-5-113-01 GDSC1 0.0391 10.0000
HS445 HG-5-88-01 GDSC1 0.0391 10.0000
HS445 HG6-64-1 GDSC1 0.0200 5.1200
HS445 HKMTI-1-005 GDSC2 0.0100 10.0000
HS445 I-BET-762 GDSC1,GDSC2 0.0100 20.0000
HS445 I-BET151 GDSC1 0.0391 10.0000
HS445 I-BRD9 GDSC2 0.0100 10.0000
HS445 I-CBP112 GDSC1 0.0391 10.0000
HS445 IAP_5620 GDSC1,GDSC2 0.0100 10.0000
HS445 IAP_7638 GDSC1 0.0391 10.0000
HS445 Ibrutinib GDSC2 0.0100 10.0000
HS445 IC-87114 GDSC1 0.0781 20.0000
HS445 ICL-SIRT078 GDSC2 0.0100 10.0000
HS445 ICL1100013 GDSC1 0.0781 20.0000
HS445 Idelalisib GDSC1 0.0781 20.0000
HS445 IGF1R_3801 GDSC2 0.0100 10.0000
HS445 IGFR_3801 GDSC1 0.0391 10.0000
HS445 Imatinib GDSC1 0.0078 2.0000
HS445 IMD-0354 GDSC1 0.0781 20.0000
HS445 IOX2 GDSC1 0.0004 0.1000
HS445 IPA-3 GDSC1 0.1250 32.0000
HS445 Ipatasertib GDSC2 0.0100 10.0000
HS445 IRAK4_4710 GDSC2 0.0100 10.0000
HS445 Irinotecan GDSC2 0.0050 10.0000
HS445 Ispinesib Mesylate GDSC1 0.0005 0.1280
HS445 IWP-2 GDSC2 0.0010 1.0000
HS445 JAK_8517 GDSC2 0.0100 10.0000
HS445 JAK1_3715 GDSC1 0.0391 10.0000
HS445 JAK1_8709 GDSC2 0.0100 10.0000
HS445 JAK3_7406 GDSC1 0.0391 10.0000
HS445 JNJ38877605 GDSC1 0.0781 20.0000
HS445 JNK Inhibitor VIII GDSC2 0.0100 10.0000
HS445 JNK-9L GDSC1 0.0200 5.1200
HS445 JQ1 GDSC1,GDSC2 0.0039 10.0000
HS445 JQ12 GDSC1 0.0200 5.1200
HS445 JW-7-24-1 GDSC1 0.0400 10.2400
HS445 JW-7-52-1 GDSC1 0.0047 1.2000
HS445 kb NB 142-70 GDSC1 0.0781 20.0000
HS445 KIN001-042 GDSC1 0.0400 10.2400
HS445 KIN001-236 GDSC1 0.0400 10.2400
HS445 KIN001-244 GDSC1 0.0781 20.0000
HS445 KIN001-260 GDSC1 0.0781 20.0000
HS445 KIN001-266 GDSC1 0.0781 20.0000
HS445 KIN001-270 GDSC1 0.0781 20.0000
HS445 Kobe2602 GDSC1 0.0781 20.0000
HS445 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
HS445 KU-55933 GDSC2 0.0100 10.0000
HS445 L-Oxonoreleagnine GDSC2 0.0030 3.0000
HS445 Lapatinib GDSC1,GDSC2 0.0078 10.0000
HS445 LCL161 GDSC1,GDSC2 0.0100 10.0000
HS445 LDN-193189 GDSC1 0.0400 10.2400
HS445 Leflunomide GDSC2 0.1001 100.0000
HS445 Lenalidomide GDSC2 0.0100 10.0000
HS445 Lestaurtinib GDSC2 0.0020 2.0000
HS445 LFM-A13 GDSC1 0.0625 16.0000
HS445 LGK974 GDSC1,GDSC2 0.0050 10.0000
HS445 LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
HS445 Linifanib GDSC1 0.0040 1.0240
HS445 Linsitinib GDSC1,GDSC2 0.0025 10.0000
HS445 LJI308 GDSC2 0.0100 10.0000
HS445 LMB_AB1 GDSC2 0.0100 10.0000
HS445 LMB_AB2 GDSC2 0.0100 10.0000
HS445 LMB_AB3 GDSC2 0.0100 10.0000
HS445 LMP744 GDSC2 0.0030 3.0000
HS445 Luminespib GDSC1,GDSC2 0.0003 1.0000
HS445 LY2109761 GDSC2 0.0100 10.0000
HS445 Masitinib GDSC1 0.0781 20.0000
HS445 MCT1_6447 GDSC1 0.0391 10.0000
HS445 MCT4_1422 GDSC1 0.0391 10.0000
HS445 MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
HS445 Methotrexate GDSC2 0.0010 1.0000
HS445 MG-132 GDSC1,GDSC2 0.0039 4.0000
HS445 Midostaurin GDSC1 0.0020 0.5120
HS445 MIM1 GDSC1,GDSC2 0.0100 40.0000
HS445 MIRA-1 GDSC2 0.0100 10.0000
HS445 Mirin GDSC1,GDSC2 0.1001 100.0000
HS445 Mitomycin-C GDSC1 0.0625 16.0000
HS445 Mitoxantrone GDSC2 0.0030 3.0000
HS445 MK-1775 GDSC2 0.0100 10.0000
HS445 MK-2206 GDSC2 0.0100 10.0000
HS445 MK-8776 GDSC2 0.0050 5.0000
HS445 ML323 GDSC2 0.0200 20.0000
HS445 MN-64 GDSC2 0.0100 10.0000
HS445 Motesanib GDSC2 0.0100 10.0000
HS445 MPS-1-IN-1 GDSC1 0.0781 20.0000
HS445 Mycophenolic acid GDSC2 0.0100 10.0000
HS445 N-acetyl cysteine GDSC2 2.0011 2000.0000
HS445 N22899-6-C1 GDSC1 0.0391 10.0000
HS445 N23918-95-7 GDSC1 0.0391 10.0000
HS445 N24798-49-A1 GDSC1 0.0391 10.0000
HS445 N25720-51-A1 GDSC2 0.0100 10.0000
HS445 N27922-53-1 GDSC2 0.0100 10.0000
HS445 N29087-69-1 GDSC2 0.0100 10.0000
HS445 N30652-18-1 GDSC2 0.0100 10.0000
HS445 Navitoclax GDSC2 0.0020 10.0000
HS445 Nelarabine GDSC2 0.0200 20.0000
HS445 NG-25 GDSC1 0.0400 10.2400
HS445 Nilotinib GDSC2 0.0020 2.0000
HS445 Niraparib GDSC2 0.0100 10.0000
HS445 NPK76-II-72-1 GDSC1 0.0400 10.2400
HS445 NSC-207895 GDSC1 0.0781 20.0000
HS445 NSC-87877 GDSC1 0.0625 16.0000
HS445 NSC319726 GDSC1 0.0010 0.2560
HS445 NU7441 GDSC2 0.0100 10.0000
HS445 Nutlin-3a GDSC2 0.0080 10.0000
HS445 NVP-ADW742 GDSC2 0.0100 10.0000
HS445 NVP-BHG712 GDSC1 0.0400 10.2400
HS445 NVP-TAE684 GDSC1 0.0078 2.0000
HS445 Obatoclax Mesylate GDSC1,GDSC2 0.0100 16.0000
HS445 OF-1 GDSC2 0.0100 10.0000
HS445 Olaparib GDSC1,GDSC2 0.0100 10.0000
HS445 Omipalisib GDSC1 0.0005 0.1280
HS445 OSI-027 GDSC1,GDSC2 0.0040 20.0000
HS445 OSI-930 GDSC1 0.0400 10.2400
HS445 Osimertinib GDSC2 0.0010 1.0000
HS445 OSU-03012 GDSC1 0.0625 16.0000
HS445 OTX015 GDSC2 0.0100 10.0000
HS445 Oxaliplatin GDSC2 0.0100 20.0000
HS445 P22077 GDSC2 0.0100 10.0000
HS445 PAC-1 GDSC1 0.0100 2.5600
HS445 Paclitaxel GDSC1,GDSC2 0.0000 0.1024
HS445 PAK_5339 GDSC2 0.0300 30.0000
HS445 Palbociclib GDSC2 0.0040 10.0000
HS445 Panobinostat GDSC1 0.0040 1.0240
HS445 PARP_0108 GDSC1 0.0098 2.5000
HS445 PARP_9482 GDSC1 0.0098 2.5000
HS445 PARP_9495 GDSC1 0.0098 2.5000
HS445 Parthenolide GDSC1 0.0195 5.0000
HS445 Pazopanib GDSC1 0.0312 8.0000
HS445 PBD-288 GDSC2 0.0050 5.0000
HS445 PCI-34051 GDSC2 0.0100 10.0000
HS445 PD0325901 GDSC2 0.0003 2.5000
HS445 PD173074 GDSC2 0.0020 10.0000
HS445 Pelitinib GDSC1 0.0098 2.5000
HS445 Pemetrexed GDSC1 0.0100 2.5600
HS445 Pevonedistat GDSC1,GDSC2 0.0039 10.0000
HS445 PF-00299804 GDSC1 0.0781 20.0000
HS445 PF-562271 GDSC1 0.0100 2.5600
HS445 PFI-1 GDSC1,GDSC2 0.0100 10.0000
HS445 PFI3 GDSC1,GDSC2 0.0100 10.0000
HS445 PHA-665752 GDSC1 0.0078 2.0000
HS445 PHA-793887 GDSC1 0.0400 10.2400
HS445 Phenformin GDSC1 15.6250 4000.0000
HS445 PI-103 GDSC1 0.0400 10.2400
HS445 PI3Ka_4409 GDSC1 0.0391 10.0000
HS445 Picolinici-acid GDSC2 0.0100 10.0000
HS445 Pictilisib GDSC1,GDSC2 0.0040 10.0000
HS445 PIK-93 GDSC1 0.0781 20.0000
HS445 Pilaralisib GDSC1 0.0781 20.0000
HS445 Piperlongumine GDSC1 0.0391 10.0000
HS445 PLK_6522 GDSC1 0.0024 0.6250
HS445 PLX-4720 GDSC1,GDSC2 0.0100 10.0000
HS445 Podophyllotoxin bromide GDSC2 0.0010 1.0000
HS445 POMHEX GDSC2 0.0100 10.0000
HS445 Ponatinib GDSC1 0.0020 0.5120
HS445 PRIMA-1MET GDSC2 0.0300 30.0000
HS445 PRT062607 GDSC2 0.0100 10.0000
HS445 Pyridostatin GDSC2 0.0100 10.0000
HS445 Pyrimethamine GDSC1 0.0781 20.0000
HS445 QL-VIII-58 GDSC1 0.0391 10.0000
HS445 QL-X-138 GDSC1 0.0400 10.2400
HS445 QL-XI-92 GDSC1 0.0400 10.2400
HS445 QL-XII-47 GDSC1 0.0400 10.2400
HS445 QL-XII-61 GDSC1 0.0391 10.0000
HS445 QS11 GDSC1 0.0400 10.2400
HS445 Quizartinib GDSC1 0.0040 1.0240
HS445 RAF_9304 GDSC1 0.0391 10.0000
HS445 Rapamycin GDSC1,GDSC2 0.0000 0.1000
HS445 Refametinib GDSC1,GDSC2 0.0100 10.0000
HS445 Remodelin GDSC2 0.0500 50.0000
HS445 Ribociclib GDSC2 0.0020 2.0000
HS445 RO-3306 GDSC2 0.0100 10.0000
HS445 Romidepsin GDSC2 0.0000 0.0100
HS445 rTRAIL GDSC1 0.0004 0.1000
HS445 RU-SKI 43 GDSC1 0.0781 20.0000
HS445 Rucaparib GDSC2 0.0050 5.0000
HS445 Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
HS445 RVX-208 GDSC2 0.0100 10.0000
HS445 S-Trityl-L-cysteine GDSC1 0.0200 5.1200
HS445 Sabutoclax GDSC2 0.0100 10.0000
HS445 Salubrinal GDSC1 0.0625 16.0000
HS445 Sapitinib GDSC2 0.0050 10.0000
HS445 Saracatinib GDSC1 0.0078 2.0000
HS445 Savolitinib GDSC2 0.0010 1.0000
HS445 SB216763 GDSC2 0.0100 10.0000
HS445 SB505124 GDSC1 0.0391 20.0000
HS445 SB52334 GDSC1 0.0781 20.0000
HS445 SB590885 GDSC2 0.0050 5.0000
HS445 SCH772984 GDSC2 0.0050 5.0000
HS445 Schweinfurthin A GDSC2 0.0010 1.0000
HS445 Seliciclib GDSC1 0.0625 16.0000
HS445 Selisistat GDSC1 0.0781 20.0000
HS445 Selumetinib GDSC1,GDSC2 0.0100 10.0000
HS445 Sepantronium bromide GDSC1,GDSC2 0.0100 10.0000
HS445 Serdemetan GDSC2 0.0100 10.0000
HS445 SGC-CBP30 GDSC2 0.0050 5.0000
HS445 SGC0946 GDSC1,GDSC2 0.0005 0.5000
HS445 Shikonin GDSC1 0.0625 16.0000
HS445 Sinularin GDSC2 0.0030 3.0000
HS445 SN-38 GDSC1,GDSC2 0.0000 0.0500
HS445 SNX-2112 GDSC1 0.0100 2.5600
HS445 Sorafenib GDSC1,GDSC2 0.0100 10.0000
HS445 Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
HS445 Staurosporine GDSC2 0.0078 2.0000
HS445 STF-62247 GDSC1 0.0400 10.2400
HS445 SU11274 GDSC1 0.0400 10.2400
HS445 Sunitinib GDSC1 0.0312 8.0000
HS445 T0901317 GDSC1 0.0400 10.2400
HS445 TAF1_5496 GDSC2 0.0100 10.0000
HS445 TAK-715 GDSC1 0.0781 20.0000
HS445 Talazoparib GDSC1,GDSC2 0.0100 10.0000
HS445 Tamoxifen GDSC1,GDSC2 0.0100 10.0000
HS445 Tanespimycin GDSC2 0.0010 1.0000
HS445 TANK_1366 GDSC1 0.0098 2.5000
HS445 Taselisib GDSC2 0.0040 10.0000
HS445 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
HS445 Temozolomide GDSC1,GDSC2 0.0300 30.0000
HS445 Temsirolimus GDSC2 0.0010 1.0000
HS445 Teniposide GDSC2 0.0030 3.0000
HS445 Tenovin-6 GDSC1 0.0781 20.0000
HS445 TGX221 GDSC1 0.0391 10.0000
HS445 Thapsigargin GDSC1 0.0020 0.5120
HS445 THR-101 GDSC2 0.0100 10.0000
HS445 THR-102 GDSC2 0.0100 10.0000
HS445 THR-103 GDSC2 0.0100 10.0000
HS445 THZ-2-102-1 GDSC1 0.0098 2.5000
HS445 THZ-2-49 GDSC1 0.0781 20.0000
HS445 Tipifarnib GDSC1 0.0625 16.0000
HS445 Tivozanib GDSC1 0.0005 0.1280
HS445 TL-1-85 GDSC1 0.0400 10.2400
HS445 TL-2-105 GDSC1 0.0400 10.2400
HS445 Topotecan GDSC2 0.0030 3.0000
HS445 Torin 2 GDSC1 0.0781 20.0000
HS445 Tozasertib GDSC1 0.0078 2.0000
HS445 TPCA-1 GDSC1 0.0781 20.0000
HS445 Trametinib GDSC1,GDSC2 0.0010 1.0000
HS445 Trichostatin A GDSC1 0.0040 1.0240
HS445 TTK_3146 GDSC1 0.0391 10.0000
HS445 Tubastatin A GDSC1 0.0781 20.0000
HS445 TWS119 GDSC1 0.0781 20.0000
HS445 Ulixertinib GDSC2 0.0020 10.0000
HS445 ULK1_4989 GDSC2 0.0300 30.0000
HS445 UMI-77 GDSC2 0.0100 10.0000
HS445 UNC0379 GDSC2 0.0100 10.0000
HS445 UNC0638 GDSC1,GDSC2 0.0050 40.0000
HS445 UNC0642 GDSC1 0.0020 0.5000
HS445 UNC1215 GDSC1 0.0039 1.0000
HS445 Uprosertib GDSC2 0.0100 10.0000
HS445 VE-822 GDSC2 0.0050 5.0000
HS445 VE821 GDSC2 0.0100 10.0000
HS445 Veliparib GDSC2 0.0100 10.0000
HS445 Venetoclax GDSC2 0.0010 1.0000
HS445 Venotoclax GDSC1 0.0010 0.2560
HS445 Vinblastine GDSC2 0.0001 0.1000
HS445 Vincristine GDSC2 0.0030 3.0000
HS445 Vinorelbine GDSC1,GDSC2 0.0001 0.1000
HS445 Vismodegib GDSC2 0.0100 10.0000
HS445 VNLG-124 GDSC1 0.0200 5.1200
HS445 Vorinostat GDSC2 0.0100 10.0000
HS445 Voxtalisib GDSC1 0.0781 20.0000
HS445 VSP34_8731 GDSC2 0.0300 30.0000
HS445 VTP-A GDSC2 0.0010 1.0000
HS445 VTP-B GDSC2 0.0010 1.0000
HS445 VX-11e GDSC1,GDSC2 0.0100 10.0000
HS445 Wee1 Inhibitor GDSC2 0.0100 10.0000
HS445 WEHI-539 GDSC2 0.0100 10.0000
HS445 WH-4-023 GDSC1 0.0200 5.1200
HS445 WHI-P97 GDSC1 0.0400 10.2400
HS445 WIKI4 GDSC2 0.0100 10.0000
HS445 Wnt-C59 GDSC1,GDSC2 0.0100 10.0000
HS445 WYE-125132 GDSC1 0.0400 10.2400
HS445 WZ-1-84 GDSC1 0.0400 10.2400
HS445 WZ3105 GDSC1 0.0050 1.2800
HS445 WZ4003 GDSC2 0.0100 10.0000
HS445 XAV939 GDSC1,GDSC2 0.0100 10.0000
HS445 XMD11-85h GDSC1 0.0391 10.0000
HS445 XMD13-2 GDSC1 0.0400 10.2400
HS445 XMD14-99 GDSC1 0.0400 10.2400
HS445 XMD15-27 GDSC1 0.0400 10.2400
HS445 XMD8-85 GDSC1 0.0312 8.0000
HS445 XMD8-92 GDSC1 0.0391 10.0000
HS445 Y-39983 GDSC1 0.0781 20.0000
HS445 YK-4-279 GDSC1,GDSC2 0.0200 20.0000
HS445 YM201636 GDSC1 0.0200 5.1200
HS445 Z-LLNle-CHO GDSC1 0.0100 2.5600
HS445 ZG-10 GDSC1 0.0391 10.0000
HS445 Zibotentan GDSC1 0.0781 20.0000
HS445 ZL049 GDSC1 0.0391 10.0000
HS445 ZL109 GDSC1 0.0391 10.0000
HS445 ZM447439 GDSC2 0.0100 10.0000
HS445 Zoledronate GDSC2 0.0020 2.0000
HS445 ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC