Cell Line : 451LU
Cellosaurus Index : CVCL_6357
Cellosaurus ID : 451LU
GDSC1 Name
, GDSC2 Name
: 451Lu
CCLE Name
: 451LU_SKIN
Cancer Type : skin
Dataset : All
Drug Response Information
Click to show/hide information cards below or download all drug response information.
Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.
Experimental information
Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.
| Cellosaurus ID | Drug Name | Original Dataset(s) | Min Dose | Max Dose | Dose-response |
|---|---|---|---|---|---|
| 451LU | (5Z)-7-Oxozeaenol | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | 5-Fluorouracil | GDSC1,GDSC2 | 0.0200 | 32.0000 |
|
| 451LU | 965-D2 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | 993-D2 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | A-83-01 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | ABT737 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | ACY-1215 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Afatinib | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| 451LU | Afuresertib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AGI-5198 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AGI-6780 | GDSC1,GDSC2 | 0.0020 | 10.0000 |
|
| 451LU | AGK-2 | GDSC2 | 0.0040 | 4.0000 |
|
| 451LU | AICA Ribonucleotide | GDSC1 | 7.8125 | 2000.0000 |
|
| 451LU | AKT inhibitor VIII | GDSC1 | 0.0100 | 10.2400 |
|
| 451LU | Alectinib | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | Alisertib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Alpelisib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AMG-319 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Amuvatinib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Apitolisib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | AR-42 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | Ara-G | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | ARRY-520 | GDSC1 | 0.0010 | 0.2560 |
|
| 451LU | AS601245 | GDSC1 | 0.0312 | 8.0000 |
|
| 451LU | AS605240 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | AST-1306 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | AT-7519 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | AT13148 | GDSC2 | 0.0080 | 8.0000 |
|
| 451LU | AT7867 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Avagacestat | GDSC1,GDSC2 | 0.0100 | 10.2400 |
|
| 451LU | Axitinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| 451LU | AZ20 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZ6102 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZ960 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZD1208 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD1332 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD1480 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | AZD2014 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD3514 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD3759 | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | AZD4547 | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| 451LU | AZD4877 | GDSC1 | 0.0002 | 0.0390 |
|
| 451LU | AZD5363 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZD5438 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD5582 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZD6094 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | AZD6482 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZD6738 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | AZD7762 | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| 451LU | AZD7969 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD8055 | GDSC1 | 0.0078 | 2.0000 |
|
| 451LU | AZD8186 | GDSC1,GDSC2 | 0.0098 | 10.0000 |
|
| 451LU | AZD8835 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | AZD8931 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAM7 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | BAY ACCi | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAY AKT1 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAY-61-3606 | GDSC1 | 0.0312 | 8.0000 |
|
| 451LU | BAY-HDAC11_1 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAY-HDAC11_2 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAY-HDAC11_4 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | BAY-MPS-combo 2 (paclitaxel 1 uM) | GDSC1 | 0.0039 | 1.0000 |
|
| 451LU | BAY-MPS-combo-1 (paclitaxel 5 uM) | GDSC1 | 0.0039 | 1.0000 |
|
| 451LU | BAY-MPS1 | GDSC1 | 0.0117 | 3.0000 |
|
| 451LU | Belinostat | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Bexarotene | GDSC1 | 0.0312 | 8.0000 |
|
| 451LU | BI-2536 | GDSC2 | 0.0005 | 0.5000 |
|
| 451LU | BIBF-1120 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | BIBR-1532 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Bicalutamide | GDSC1,GDSC2 | 0.0040 | 10.0000 |
|
| 451LU | BIX02189 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Bleomycin | GDSC1 | 0.2500 | 64.0000 |
|
| 451LU | Bleomycin (10 uM) | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Bleomycin (50 uM) | GDSC1 | 0.1953 | 50.0000 |
|
| 451LU | BMS-345541 | GDSC1,GDSC2 | 0.0100 | 16.0000 |
|
| 451LU | BMS-536924 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | BMS-754807 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Bortezomib | GDSC2 | 0.0000 | 0.0200 |
|
| 451LU | Bosutinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | BPTES | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Brivanib, BMS-540215 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Bryostatin 1 | GDSC1 | 0.0000 | 0.0080 |
|
| 451LU | Buparlisib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | BX-912 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | BX795 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | C-75 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Cabozantinib | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | Camptothecin | GDSC2 | 0.0001 | 0.1000 |
|
| 451LU | CAP-232, TT-232, TLN-232 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Capivasertib | GDSC1 | 0.1172 | 30.0000 |
|
| 451LU | CAY10566 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | CAY10603 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | CCT-018159 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | CCT007093 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | CCT245232 | GDSC1 | 0.0008 | 0.2000 |
|
| 451LU | CCT245467 | GDSC1 | 0.0008 | 0.2000 |
|
| 451LU | CD532 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | Cediranib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Cetuximab | GDSC1 | 0.2570 | 65.8000 |
|
| 451LU | CHIR-99021 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | CI-1033 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | CI-1040 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Cisplatin | GDSC1 | 0.0117 | 10.0000 |
|
| 451LU | CP466722 | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | CP724714 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | CPI-613 | GDSC1 | 1.0000 | 256.0000 |
|
| 451LU | Crizotinib | GDSC2 | 0.0040 | 8.0000 |
|
| 451LU | CRT0105446 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | CRT0105950 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | CRT0160829 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | CUDC-101 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | CX-5461 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Cyclophosphamide | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Cytarabine | GDSC1 | 0.0078 | 2.0000 |
|
| 451LU | CZC24832 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Dabrafenib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Dacinostat | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | Dactinomycin | GDSC2 | 0.0008 | 0.8000 |
|
| 451LU | Dactolisib | GDSC1,GDSC2 | 0.0003 | 0.2500 |
|
| 451LU | Daporinad | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | Dasatinib | GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | Dinaciclib | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | DMOG | GDSC1 | 15.6250 | 4000.0000 |
|
| 451LU | Docetaxel | GDSC1,GDSC2 | 0.0000 | 0.0125 |
|
| 451LU | Doramapimod | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Doxorubicin | GDSC1 | 0.0040 | 5.0000 |
|
| 451LU | Dyrk1b_0191 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | eEF2K Inhibitor, A-484954 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | EHT-1864 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Elesclomol | GDSC1,GDSC2 | 0.0002 | 0.2000 |
|
| 451LU | Embelin | GDSC1 | 0.1250 | 32.0000 |
|
| 451LU | Entinostat | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Entospletinib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Enzastaurin | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | EphB4_9721 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Epirubicin | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Epothilone B | GDSC1 | 0.0001 | 0.0320 |
|
| 451LU | EPZ004777 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | EPZ5676 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Erlotinib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Etoposide | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | ETP-45835 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Fedratinib | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | FEN1_3940 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | FGFR_0939 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | FGFR_3831 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | FH535 | GDSC1 | 0.1250 | 32.0000 |
|
| 451LU | Flavopiridol | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | FMK | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Foretinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | FR-180204 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | FS106 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | FS112 | GDSC1 | 0.0195 | 5.0000 |
|
| 451LU | FTI-277 | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | FTY-720 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Fulvestrant | GDSC1,GDSC2 | 0.0010 | 10.0000 |
|
| 451LU | FY012 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | FY026 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | FY069 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | GDC0810 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Gefitinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | Gemcitabine | GDSC1,GDSC2 | 0.0002 | 10.0000 |
|
| 451LU | Genentech Cpd 10 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | GNE-317 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | GSK-J4 | GDSC1 | 0.1172 | 30.0000 |
|
| 451LU | GSK1059615 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | GSK1070916 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | GSK1904529A | GDSC1,GDSC2 | 0.0040 | 5.0000 |
|
| 451LU | GSK2578215A | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | GSK2606414 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | GSK269962A | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | GSK343 | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | GSK429286A | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | GSK591 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | GSK650394 | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | GSK690693 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | GW-2580 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | GW441756 | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | HG-5-113-01 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | HG-5-88-01 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | HG6-64-1 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | I-BET-762 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| 451LU | I-BET151 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | I-BRD9 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | I-CBP112 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | IAP_5620 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | IAP_7638 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Ibrutinib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | IC-87114 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | ICL1100013 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Idelalisib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | IGFR_3801 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | IMD-0354 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | IOX2 | GDSC1,GDSC2 | 0.0004 | 0.5000 |
|
| 451LU | IPA-3 | GDSC1 | 0.1250 | 32.0000 |
|
| 451LU | Ipatasertib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Irinotecan | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | Ispinesib Mesylate | GDSC1 | 0.0005 | 0.1280 |
|
| 451LU | IWP-2 | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | JAK1_3715 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | JAK3_7406 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | JNJ38877605 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | JNK Inhibitor VIII | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | JNK-9L | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | JQ1 | GDSC1,GDSC2 | 0.0039 | 10.0000 |
|
| 451LU | JQ12 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | JW-7-24-1 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | kb NB 142-70 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | KIN001-042 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | KIN001-236 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | KIN001-244 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | KIN001-260 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | KIN001-266 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | KIN001-270 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Kobe2602 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | KRAS (G12C) Inhibitor-12 | GDSC2 | 0.0200 | 20.0000 |
|
| 451LU | KU-55933 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | KU-60019 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Lapatinib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | LCL161 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | LDN-193189 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Leflunomide | GDSC2 | 0.1001 | 100.0000 |
|
| 451LU | Lenalidomide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Lestaurtinib | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | LFM-A13 | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | LGK974 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | LIMK1 inhibitor BMS4 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Linifanib | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | Linsitinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | LJI308 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Luminespib | GDSC1,GDSC2 | 0.0003 | 0.2560 |
|
| 451LU | LY2109761 | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | Masitinib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | MCT1_6447 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | MCT4_1422 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | MetAP2 Inhibitor, A832234 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | Methotrexate | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| 451LU | MG-132 | GDSC2 | 0.0040 | 4.0000 |
|
| 451LU | Midostaurin | GDSC1 | 0.0020 | 0.5120 |
|
| 451LU | MIM1 | GDSC1 | 0.1562 | 40.0000 |
|
| 451LU | MIRA-1 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Mirin | GDSC1,GDSC2 | 0.1001 | 100.0000 |
|
| 451LU | Mitomycin-C | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | MK-1775 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | MK-2206 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | MK-8776 | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | ML323 | GDSC2 | 0.0200 | 20.0000 |
|
| 451LU | MN-64 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Motesanib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| 451LU | MPS-1-IN-1 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | N22899-6-C1 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | N23918-95-7 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | N24798-49-A1 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Navitoclax | GDSC1,GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | NG-25 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Nilotinib | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| 451LU | Niraparib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | NPK76-II-72-1 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | NSC-207895 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | NSC-87877 | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | NSC319726 | GDSC1 | 0.0010 | 0.2560 |
|
| 451LU | NU7441 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| 451LU | Nutlin-3a | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | NVP-ADW742 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | NVP-BHG712 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Obatoclax Mesylate | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | OF-1 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Olaparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Omipalisib | GDSC1 | 0.0005 | 0.1280 |
|
| 451LU | OSI-027 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| 451LU | OSI-930 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Osimertinib | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | OSU-03012 | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | OTX015 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Oxaliplatin | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | P22077 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PAC-1 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | Paclitaxel | GDSC2 | 0.0001 | 0.1000 |
|
| 451LU | Palbociclib | GDSC1,GDSC2 | 0.0040 | 4.0000 |
|
| 451LU | Panobinostat | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | PARP_0108 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | PARP_9482 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | PARP_9495 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | Pazopanib | GDSC1 | 0.0312 | 8.0000 |
|
| 451LU | PCI-34051 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PD0325901 | GDSC1,GDSC2 | 0.0010 | 2.5000 |
|
| 451LU | PD173074 | GDSC1,GDSC2 | 0.0078 | 10.0000 |
|
| 451LU | Pelitinib | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | Pemetrexed | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | Pevonedistat | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PF-00299804 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | PF-4708671 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PF-562271 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | PFI-1 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PFI3 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PHA-793887 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Phenformin | GDSC1 | 15.6250 | 4000.0000 |
|
| 451LU | PI-103 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | PI3Ka_4409 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Picolinici-acid | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Pictilisib | GDSC1,GDSC2 | 0.0040 | 4.0000 |
|
| 451LU | PIK-93 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Pilaralisib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Piperlongumine | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | PLK_6522 | GDSC1 | 0.0024 | 0.6250 |
|
| 451LU | PLX-4720 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Ponatinib | GDSC1 | 0.0020 | 0.5120 |
|
| 451LU | PRIMA-1MET | GDSC2 | 0.0300 | 30.0000 |
|
| 451LU | PRT062607 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Pyridostatin | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | QL-VIII-58 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | QL-X-138 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | QL-XI-92 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | QL-XII-47 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | QL-XII-61 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | QS11 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Quizartinib | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | RAF_9304 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Rapamycin | GDSC2 | 0.0001 | 0.1000 |
|
| 451LU | Refametinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Ribociclib | GDSC2 | 0.0020 | 2.0000 |
|
| 451LU | RO-3306 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | rTRAIL | GDSC1 | 0.0004 | 0.1000 |
|
| 451LU | RU-SKI 43 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Rucaparib | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | Ruxolitinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | RVX-208 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Sabutoclax | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Sapitinib | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | Savolitinib | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | SB216763 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | SB505124 | GDSC1,GDSC2 | 0.0100 | 20.0000 |
|
| 451LU | SB52334 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | SB590885 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | SCH772984 | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | Selisistat | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Selumetinib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Sepantronium bromide | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Serdemetan | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | SGC0946 | GDSC1,GDSC2 | 0.0005 | 0.5000 |
|
| 451LU | Shikonin | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | SL0101 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | SN-38 | GDSC1,GDSC2 | 0.0002 | 10.0000 |
|
| 451LU | SNX-2112 | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | Sorafenib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Sphingosine Kinase 1 Inhibitor II | GDSC1 | 0.0100 | 2.5600 |
|
| 451LU | Staurosporine | GDSC2 | 0.0078 | 2.0000 |
|
| 451LU | STF-62247 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | SU11274 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | T0901317 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | TAK-715 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Talazoparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Tamoxifen | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Tanespimycin | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | TANK_1366 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | Taselisib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Telomerase Inhibitor IX | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Temozolomide | GDSC1,GDSC2 | 0.0300 | 30.0000 |
|
| 451LU | Temsirolimus | GDSC1,GDSC2 | 0.0008 | 1.0000 |
|
| 451LU | Tenovin-6 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Thapsigargin | GDSC1 | 0.0020 | 0.5120 |
|
| 451LU | THZ-2-102-1 | GDSC1 | 0.0098 | 2.5000 |
|
| 451LU | THZ-2-49 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Tipifarnib | GDSC1 | 0.0625 | 16.0000 |
|
| 451LU | Tivozanib | GDSC1 | 0.0005 | 0.1280 |
|
| 451LU | TL-1-85 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | TL-2-105 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | Torin 2 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Tozasertib | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | TPCA-1 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Trametinib | GDSC1,GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | Tretinoin | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Trichostatin A | GDSC1 | 0.0040 | 1.0240 |
|
| 451LU | TTK_3146 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Tubastatin A | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | TW 37 | GDSC1 | 0.0195 | 5.0000 |
|
| 451LU | TWS119 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | Ulixertinib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | UNC0638 | GDSC1 | 0.0781 | 40.0000 |
|
| 451LU | UNC0642 | GDSC1 | 0.0020 | 0.5000 |
|
| 451LU | UNC1215 | GDSC1 | 0.0039 | 1.0000 |
|
| 451LU | Uprosertib | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | VE-822 | GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | VE821 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Veliparib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Venetoclax | GDSC2 | 0.0010 | 1.0000 |
|
| 451LU | Venotoclax | GDSC1 | 0.0010 | 0.2560 |
|
| 451LU | Vinblastine | GDSC1 | 0.0004 | 0.1000 |
|
| 451LU | Vinorelbine | GDSC1,GDSC2 | 0.0001 | 0.1000 |
|
| 451LU | Vismodegib | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | VNLG-124 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | Vorinostat | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Voxtalisib | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | VX-11e | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | VX-702 | GDSC1 | 0.0078 | 2.0000 |
|
| 451LU | Wee1 Inhibitor | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | WEHI-539 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | WHI-P97 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | WIKI4 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | Wnt-C59 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | WYE-125132 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | WZ3105 | GDSC1 | 0.0050 | 1.2800 |
|
| 451LU | WZ4003 | GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | XAV939 | GDSC1,GDSC2 | 0.0050 | 5.0000 |
|
| 451LU | XMD11-85h | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | XMD13-2 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | XMD14-99 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | XMD15-27 | GDSC1 | 0.0400 | 10.2400 |
|
| 451LU | XMD8-92 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Y-39983 | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | YK-4-279 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | YM201636 | GDSC1 | 0.0200 | 5.1200 |
|
| 451LU | ZG-10 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | Zibotentan | GDSC1 | 0.0781 | 20.0000 |
|
| 451LU | ZL049 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | ZL109 | GDSC1 | 0.0391 | 10.0000 |
|
| 451LU | ZM447439 | GDSC1,GDSC2 | 0.0100 | 10.0000 |
|
| 451LU | ZSTK474 | GDSC1 | 0.0200 | 5.1200 |
|
IC50
IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.
Drugs with highest and lowest IC50
Drugs with highest and lowest IC50
IC90
IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.
Drugs with highest and lowest IC90
Drugs with highest and lowest IC90
AUC
AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.
Drugs with highest and lowest AUC
Drugs with highest and lowest AUC