Cell Line : STS-0421

Cellosaurus Index : CVCL_X508
Cellosaurus ID : STS-0421

GDSC1 Name , GDSC2 Name : STS-0421
CCLE Name : STS0421_SOFT_TISSUE

Cancer Type : soft_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
STS-0421 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
STS-0421 5-Fluorouracil GDSC2 0.0200 20.0000
STS-0421 965-D2 GDSC1 0.0391 10.0000
STS-0421 993-D2 GDSC1 0.0391 10.0000
STS-0421 ABT737 GDSC2 0.0100 10.0000
STS-0421 Afatinib GDSC1,GDSC2 0.0020 10.0000
STS-0421 Afuresertib GDSC2 0.0100 10.0000
STS-0421 AGI-5198 GDSC2 0.0100 10.0000
STS-0421 AGI-6780 GDSC2 0.0100 10.0000
STS-0421 AGK-2 GDSC2 0.0040 4.0000
STS-0421 AICA Ribonucleotide GDSC1 7.8125 2000.0000
STS-0421 AKT inhibitor VIII GDSC1 0.0100 10.2400
STS-0421 Alisertib GDSC2 0.0100 10.0000
STS-0421 Alpelisib GDSC2 0.0100 10.0000
STS-0421 AMG-319 GDSC2 0.0100 10.0000
STS-0421 AS601245 GDSC1 0.0312 8.0000
STS-0421 AS605240 GDSC1 0.0781 20.0000
STS-0421 AT-7519 GDSC1 0.0400 10.2400
STS-0421 AT13148 GDSC2 0.0080 8.0000
STS-0421 Avagacestat GDSC1,GDSC2 0.0100 10.0000
STS-0421 Axitinib GDSC1,GDSC2 0.0078 10.0000
STS-0421 AZ20 GDSC1 0.0391 10.0000
STS-0421 AZ6102 GDSC2 0.0100 10.0000
STS-0421 AZ960 GDSC2 0.0100 10.0000
STS-0421 AZD1208 GDSC1 0.0391 10.0000
STS-0421 AZD1332 GDSC1 0.0391 10.0000
STS-0421 AZD1480 GDSC1 0.0098 2.5000
STS-0421 AZD2014 GDSC1 0.0391 10.0000
STS-0421 AZD3514 GDSC1 0.0391 10.0000
STS-0421 AZD3759 GDSC2 0.0010 1.0000
STS-0421 AZD4547 GDSC1,GDSC2 0.0039 10.0000
STS-0421 AZD4877 GDSC1 0.0002 0.0390
STS-0421 AZD5363 GDSC2 0.0100 10.0000
STS-0421 AZD5438 GDSC1 0.0391 10.0000
STS-0421 AZD5582 GDSC1,GDSC2 0.0100 10.0000
STS-0421 AZD6094 GDSC1 0.0098 2.5000
STS-0421 AZD6482 GDSC1,GDSC2 0.0100 10.0000
STS-0421 AZD6738 GDSC1,GDSC2 0.0100 10.0000
STS-0421 AZD7762 GDSC1,GDSC2 0.0010 10.0000
STS-0421 AZD7969 GDSC1 0.0391 10.0000
STS-0421 AZD8055 GDSC1 0.0078 2.0000
STS-0421 AZD8186 GDSC1,GDSC2 0.0098 10.0000
STS-0421 AZD8835 GDSC1 0.0391 10.0000
STS-0421 AZD8931 GDSC1 0.0391 10.0000
STS-0421 BAY ACCi GDSC1 0.0391 10.0000
STS-0421 BAY AKT1 GDSC1 0.0391 10.0000
STS-0421 BAY-61-3606 GDSC1 0.0312 8.0000
STS-0421 BAY-HDAC11_1 GDSC1 0.0391 10.0000
STS-0421 BAY-HDAC11_2 GDSC1 0.0391 10.0000
STS-0421 BAY-HDAC11_4 GDSC1 0.0391 10.0000
STS-0421 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
STS-0421 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
STS-0421 BAY-MPS1 GDSC1 0.0117 3.0000
STS-0421 Bexarotene GDSC1 0.0312 8.0000
STS-0421 BI-2536 GDSC2 0.0005 0.5000
STS-0421 BIBR-1532 GDSC2 0.0100 10.0000
STS-0421 Bicalutamide GDSC1,GDSC2 0.0040 10.0000
STS-0421 Bleomycin GDSC1 0.2500 64.0000
STS-0421 Bleomycin (10 uM) GDSC1 0.0391 10.0000
STS-0421 Bleomycin (50 uM) GDSC1 0.1953 50.0000
STS-0421 BMS-345541 GDSC1,GDSC2 0.0100 16.0000
STS-0421 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
STS-0421 BMS-754807 GDSC1,GDSC2 0.0100 10.0000
STS-0421 Bortezomib GDSC2 0.0000 0.0200
STS-0421 Bosutinib GDSC1,GDSC2 0.0020 2.0000
STS-0421 BPTES GDSC1 0.0391 10.0000
STS-0421 Bryostatin 1 GDSC1 0.0000 0.0080
STS-0421 Buparlisib GDSC2 0.0100 10.0000
STS-0421 BX-912 GDSC1 0.0400 10.2400
STS-0421 BX795 GDSC1,GDSC2 0.0100 10.0000
STS-0421 Camptothecin GDSC2 0.0001 0.1000
STS-0421 Capivasertib GDSC1 0.1172 30.0000
STS-0421 CCT-018159 GDSC1,GDSC2 0.0100 10.0000
STS-0421 CCT007093 GDSC1,GDSC2 0.0100 10.0000
STS-0421 CCT245232 GDSC1 0.0008 0.2000
STS-0421 CCT245467 GDSC1 0.0008 0.2000
STS-0421 Cediranib GDSC2 0.0100 10.0000
STS-0421 Cetuximab GDSC1 0.2570 65.8000
STS-0421 CHIR-99021 GDSC1,GDSC2 0.0100 10.0000
STS-0421 CI-1040 GDSC1 0.0391 10.0000
STS-0421 Cisplatin GDSC1 0.0117 10.0000
STS-0421 CP466722 GDSC1 0.0625 16.0000
STS-0421 Crizotinib GDSC2 0.0040 8.0000
STS-0421 CRT0105446 GDSC1 0.0391 10.0000
STS-0421 CRT0105950 GDSC1 0.0391 10.0000
STS-0421 CRT0160829 GDSC1 0.0781 20.0000
STS-0421 Cyclophosphamide GDSC2 0.0100 10.0000
STS-0421 Cytarabine GDSC1 0.0078 2.0000
STS-0421 CZC24832 GDSC2 0.0100 10.0000
STS-0421 Dabrafenib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Dacinostat GDSC1 0.0040 1.0240
STS-0421 Dactinomycin GDSC2 0.0008 0.8000
STS-0421 Dactolisib GDSC1,GDSC2 0.0003 0.2500
STS-0421 Daporinad GDSC1,GDSC2 0.0010 1.0000
STS-0421 Dasatinib GDSC2 0.0020 2.0000
STS-0421 Dinaciclib GDSC2 0.0010 1.0000
STS-0421 DMOG GDSC1 15.6250 4000.0000
STS-0421 Docetaxel GDSC1,GDSC2 0.0000 0.0125
STS-0421 Doramapimod GDSC1,GDSC2 0.0100 10.0000
STS-0421 Doxorubicin GDSC1 0.0040 5.0000
STS-0421 Dyrk1b_0191 GDSC1 0.0391 10.0000
STS-0421 EHT-1864 GDSC1,GDSC2 0.0100 10.0000
STS-0421 Elesclomol GDSC1,GDSC2 0.0002 0.2000
STS-0421 Embelin GDSC1 0.1250 32.0000
STS-0421 Entinostat GDSC2 0.0100 10.0000
STS-0421 Entospletinib GDSC2 0.0100 10.0000
STS-0421 Enzastaurin GDSC1 0.0781 20.0000
STS-0421 EphB4_9721 GDSC1 0.0391 10.0000
STS-0421 Epirubicin GDSC2 0.0100 10.0000
STS-0421 Epothilone B GDSC1 0.0001 0.0320
STS-0421 EPZ004777 GDSC2 0.0100 10.0000
STS-0421 EPZ5676 GDSC2 0.0100 10.0000
STS-0421 Erlotinib GDSC2 0.0100 10.0000
STS-0421 Etoposide GDSC1 0.0625 16.0000
STS-0421 FEN1_3940 GDSC1 0.0391 10.0000
STS-0421 FGFR_0939 GDSC1 0.0098 2.5000
STS-0421 FGFR_3831 GDSC1 0.0391 10.0000
STS-0421 FH535 GDSC1 0.1250 32.0000
STS-0421 FMK GDSC1 0.0781 20.0000
STS-0421 Foretinib GDSC2 0.0100 10.0000
STS-0421 FS106 GDSC1 0.0391 10.0000
STS-0421 FS112 GDSC1 0.0195 5.0000
STS-0421 FTI-277 GDSC1 0.0040 1.0240
STS-0421 Fulvestrant GDSC1,GDSC2 0.0010 10.0000
STS-0421 FY012 GDSC1 0.0391 10.0000
STS-0421 FY026 GDSC1 0.0391 10.0000
STS-0421 FY069 GDSC1 0.0391 10.0000
STS-0421 GDC0810 GDSC2 0.0100 10.0000
STS-0421 Gefitinib GDSC1,GDSC2 0.0020 2.0000
STS-0421 Gemcitabine GDSC1,GDSC2 0.0002 10.0000
STS-0421 Genentech Cpd 10 GDSC1 0.0400 10.2400
STS-0421 GNE-317 GDSC2 0.0100 10.0000
STS-0421 GSK-J4 GDSC1 0.1172 30.0000
STS-0421 GSK1070916 GDSC1 0.0100 2.5600
STS-0421 GSK1904529A GDSC1,GDSC2 0.0040 5.0000
STS-0421 GSK2578215A GDSC2 0.0100 10.0000
STS-0421 GSK2606414 GDSC2 0.0100 10.0000
STS-0421 GSK269962A GDSC1,GDSC2 0.0100 10.0000
STS-0421 GSK343 GDSC2 0.0010 1.0000
STS-0421 GSK429286A GDSC1 0.0781 20.0000
STS-0421 GSK591 GDSC2 0.0100 10.0000
STS-0421 GSK650394 GDSC1 0.0625 16.0000
STS-0421 GW441756 GDSC1,GDSC2 0.0020 2.0000
STS-0421 HG-5-113-01 GDSC1 0.0391 10.0000
STS-0421 HG-5-88-01 GDSC1 0.0391 10.0000
STS-0421 HG6-64-1 GDSC1 0.0200 5.1200
STS-0421 I-BET-762 GDSC2 0.0100 10.0000
STS-0421 I-BET151 GDSC1 0.0391 10.0000
STS-0421 I-BRD9 GDSC2 0.0100 10.0000
STS-0421 I-CBP112 GDSC1 0.0391 10.0000
STS-0421 IAP_5620 GDSC1 0.0391 10.0000
STS-0421 IAP_7638 GDSC1 0.0391 10.0000
STS-0421 Ibrutinib GDSC2 0.0100 10.0000
STS-0421 ICL1100013 GDSC1 0.0781 20.0000
STS-0421 Idelalisib GDSC1 0.0781 20.0000
STS-0421 IGFR_3801 GDSC1 0.0391 10.0000
STS-0421 IOX2 GDSC1,GDSC2 0.0004 0.5000
STS-0421 IPA-3 GDSC1 0.1250 32.0000
STS-0421 Ipatasertib GDSC2 0.0100 10.0000
STS-0421 Irinotecan GDSC2 0.0050 5.0000
STS-0421 Ispinesib Mesylate GDSC1 0.0005 0.1280
STS-0421 IWP-2 GDSC2 0.0010 1.0000
STS-0421 JAK1_3715 GDSC1 0.0391 10.0000
STS-0421 JAK3_7406 GDSC1 0.0391 10.0000
STS-0421 JNK Inhibitor VIII GDSC1,GDSC2 0.0100 10.0000
STS-0421 JNK-9L GDSC1 0.0200 5.1200
STS-0421 JQ1 GDSC1,GDSC2 0.0039 10.0000
STS-0421 JQ12 GDSC1 0.0200 5.1200
STS-0421 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
STS-0421 KU-55933 GDSC1,GDSC2 0.0100 10.0000
STS-0421 KU-60019 GDSC1 0.0391 10.0000
STS-0421 Lapatinib GDSC2 0.0100 10.0000
STS-0421 LCL161 GDSC2 0.0100 10.0000
STS-0421 Leflunomide GDSC2 0.1001 100.0000
STS-0421 Lenalidomide GDSC1,GDSC2 0.0100 10.0000
STS-0421 Lestaurtinib GDSC1,GDSC2 0.0020 2.0000
STS-0421 LFM-A13 GDSC1 0.0625 16.0000
STS-0421 LGK974 GDSC2 0.0100 10.0000
STS-0421 Linsitinib GDSC1,GDSC2 0.0100 10.0000
STS-0421 LJI308 GDSC2 0.0100 10.0000
STS-0421 Luminespib GDSC1,GDSC2 0.0003 0.2560
STS-0421 LY2109761 GDSC2 0.0050 5.0000
STS-0421 MCT1_6447 GDSC1 0.0391 10.0000
STS-0421 MCT4_1422 GDSC1 0.0391 10.0000
STS-0421 Methotrexate GDSC1,GDSC2 0.0008 1.0000
STS-0421 MG-132 GDSC2 0.0040 4.0000
STS-0421 Midostaurin GDSC1 0.0020 0.5120
STS-0421 MIRA-1 GDSC2 0.0100 10.0000
STS-0421 Mirin GDSC1,GDSC2 0.1001 100.0000
STS-0421 Mitomycin-C GDSC1 0.0625 16.0000
STS-0421 MK-1775 GDSC2 0.0100 10.0000
STS-0421 MK-2206 GDSC1,GDSC2 0.0100 10.0000
STS-0421 MK-8776 GDSC2 0.0050 5.0000
STS-0421 ML323 GDSC2 0.0200 20.0000
STS-0421 MN-64 GDSC2 0.0100 10.0000
STS-0421 Motesanib GDSC1,GDSC2 0.0078 10.0000
STS-0421 N22899-6-C1 GDSC1 0.0391 10.0000
STS-0421 N23918-95-7 GDSC1 0.0391 10.0000
STS-0421 N24798-49-A1 GDSC1 0.0391 10.0000
STS-0421 Navitoclax GDSC1,GDSC2 0.0020 2.0000
STS-0421 Nilotinib GDSC1,GDSC2 0.0078 10.0000
STS-0421 Niraparib GDSC2 0.0100 10.0000
STS-0421 NSC-87877 GDSC1 0.0625 16.0000
STS-0421 NU7441 GDSC1,GDSC2 0.0078 10.0000
STS-0421 Nutlin-3a GDSC1,GDSC2 0.0100 10.0000
STS-0421 NVP-ADW742 GDSC2 0.0100 10.0000
STS-0421 Obatoclax Mesylate GDSC1 0.0625 16.0000
STS-0421 OF-1 GDSC2 0.0100 10.0000
STS-0421 Olaparib GDSC1,GDSC2 0.0100 10.0000
STS-0421 OSI-027 GDSC2 0.0100 10.0000
STS-0421 Osimertinib GDSC2 0.0010 1.0000
STS-0421 OSU-03012 GDSC1 0.0625 16.0000
STS-0421 OTX015 GDSC2 0.0100 10.0000
STS-0421 Oxaliplatin GDSC2 0.0100 10.0000
STS-0421 P22077 GDSC2 0.0100 10.0000
STS-0421 PAC-1 GDSC1 0.0100 2.5600
STS-0421 Paclitaxel GDSC2 0.0001 0.1000
STS-0421 Palbociclib GDSC1,GDSC2 0.0040 4.0000
STS-0421 PARP_0108 GDSC1 0.0098 2.5000
STS-0421 PARP_9482 GDSC1 0.0098 2.5000
STS-0421 PARP_9495 GDSC1 0.0098 2.5000
STS-0421 Pazopanib GDSC1 0.0312 8.0000
STS-0421 PCI-34051 GDSC2 0.0100 10.0000
STS-0421 PD0325901 GDSC1,GDSC2 0.0010 2.5000
STS-0421 PD173074 GDSC1,GDSC2 0.0078 10.0000
STS-0421 Pevonedistat GDSC2 0.0100 10.0000
STS-0421 PF-4708671 GDSC1,GDSC2 0.0100 10.0000
STS-0421 PF-562271 GDSC1 0.0100 2.5600
STS-0421 PFI-1 GDSC1,GDSC2 0.0100 10.0000
STS-0421 PFI3 GDSC1,GDSC2 0.0100 10.0000
STS-0421 PI3Ka_4409 GDSC1 0.0391 10.0000
STS-0421 Picolinici-acid GDSC2 0.0100 10.0000
STS-0421 Pictilisib GDSC1,GDSC2 0.0040 4.0000
STS-0421 Piperlongumine GDSC1,GDSC2 0.0100 10.0000
STS-0421 PLK_6522 GDSC1 0.0024 0.6250
STS-0421 PLX-4720 GDSC1,GDSC2 0.0100 10.0000
STS-0421 Ponatinib GDSC1 0.0020 0.5120
STS-0421 PRIMA-1MET GDSC2 0.0300 30.0000
STS-0421 PRT062607 GDSC2 0.0100 10.0000
STS-0421 Pyridostatin GDSC2 0.0100 10.0000
STS-0421 QL-VIII-58 GDSC1 0.0391 10.0000
STS-0421 QL-XII-47 GDSC1 0.0400 10.2400
STS-0421 QL-XII-61 GDSC1 0.0391 10.0000
STS-0421 QS11 GDSC1 0.0400 10.2400
STS-0421 RAF_9304 GDSC1 0.0391 10.0000
STS-0421 Rapamycin GDSC2 0.0001 0.1000
STS-0421 Refametinib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Ribociclib GDSC2 0.0020 2.0000
STS-0421 RO-3306 GDSC1,GDSC2 0.0100 10.0000
STS-0421 rTRAIL GDSC1 0.0004 0.1000
STS-0421 Rucaparib GDSC1,GDSC2 0.0050 5.0000
STS-0421 Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
STS-0421 RVX-208 GDSC2 0.0100 10.0000
STS-0421 Sabutoclax GDSC2 0.0100 10.0000
STS-0421 Sapitinib GDSC2 0.0050 5.0000
STS-0421 Savolitinib GDSC2 0.0010 1.0000
STS-0421 SB216763 GDSC1,GDSC2 0.0100 10.0000
STS-0421 SB505124 GDSC1,GDSC2 0.0100 10.0000
STS-0421 SB590885 GDSC1,GDSC2 0.0050 5.0000
STS-0421 SCH772984 GDSC2 0.0050 5.0000
STS-0421 Selumetinib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Sepantronium bromide GDSC2 0.0100 10.0000
STS-0421 Serdemetan GDSC1,GDSC2 0.0100 10.0000
STS-0421 SGC0946 GDSC1,GDSC2 0.0005 0.5000
STS-0421 Shikonin GDSC1 0.0625 16.0000
STS-0421 SL0101 GDSC1,GDSC2 0.0100 10.0000
STS-0421 SN-38 GDSC1,GDSC2 0.0002 10.0000
STS-0421 Sorafenib GDSC2 0.0100 10.0000
STS-0421 Staurosporine GDSC2 0.0078 2.0000
STS-0421 TAK-715 GDSC1 0.0781 20.0000
STS-0421 Talazoparib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Tamoxifen GDSC1,GDSC2 0.0100 10.0000
STS-0421 Tanespimycin GDSC1,GDSC2 0.0010 1.0000
STS-0421 TANK_1366 GDSC1 0.0098 2.5000
STS-0421 Taselisib GDSC2 0.0100 10.0000
STS-0421 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
STS-0421 Temozolomide GDSC1,GDSC2 0.0300 30.0000
STS-0421 Temsirolimus GDSC1,GDSC2 0.0008 1.0000
STS-0421 Thapsigargin GDSC1 0.0020 0.5120
STS-0421 Tipifarnib GDSC1 0.0625 16.0000
STS-0421 TL-2-105 GDSC1 0.0400 10.2400
STS-0421 Tozasertib GDSC2 0.0050 5.0000
STS-0421 Trametinib GDSC1,GDSC2 0.0010 1.0000
STS-0421 Tretinoin GDSC1,GDSC2 0.0100 10.0000
STS-0421 TTK_3146 GDSC1 0.0391 10.0000
STS-0421 TW 37 GDSC1 0.0195 5.0000
STS-0421 Ulixertinib GDSC2 0.0100 10.0000
STS-0421 UNC0638 GDSC1 0.0781 20.0000
STS-0421 UNC0642 GDSC1 0.0020 0.5000
STS-0421 UNC1215 GDSC1 0.0039 1.0000
STS-0421 Uprosertib GDSC2 0.0100 10.0000
STS-0421 VE-822 GDSC2 0.0050 5.0000
STS-0421 VE821 GDSC2 0.0100 10.0000
STS-0421 Veliparib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Venetoclax GDSC2 0.0010 1.0000
STS-0421 Vinblastine GDSC1 0.0004 0.1000
STS-0421 Vinorelbine GDSC1,GDSC2 0.0001 0.1000
STS-0421 Vismodegib GDSC1,GDSC2 0.0100 10.0000
STS-0421 Vorinostat GDSC1,GDSC2 0.0100 10.0000
STS-0421 VX-11e GDSC2 0.0100 10.0000
STS-0421 VX-702 GDSC1 0.0078 2.0000
STS-0421 Wee1 Inhibitor GDSC1,GDSC2 0.0078 10.0000
STS-0421 WEHI-539 GDSC2 0.0100 10.0000
STS-0421 WIKI4 GDSC2 0.0100 10.0000
STS-0421 Wnt-C59 GDSC2 0.0100 10.0000
STS-0421 WZ4003 GDSC2 0.0100 10.0000
STS-0421 XAV939 GDSC1,GDSC2 0.0050 5.0000
STS-0421 XMD11-85h GDSC1 0.0391 10.0000
STS-0421 XMD8-92 GDSC1 0.0391 10.0000
STS-0421 YK-4-279 GDSC1,GDSC2 0.0100 10.0000
STS-0421 ZG-10 GDSC1 0.0391 10.0000
STS-0421 ZL049 GDSC1 0.0391 10.0000
STS-0421 ZL109 GDSC1 0.0391 10.0000
STS-0421 ZM447439 GDSC1,GDSC2 0.0100 10.0000
STS-0421 ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC