Cell Line : JHU-029

Cellosaurus Index : CVCL_5993
Cellosaurus ID : JHU-029

CCLE Name : JHU029_UPPER_AERODIGESTIVE_TRACT
GDSC1 Name , GDSC2 Name : JHU-029

Cancer Type : upper_aerodigestive_tract
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
JHU-029 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
JHU-029 5-Fluorouracil GDSC2 0.0200 20.0000
JHU-029 965-D2 GDSC1 0.0391 10.0000
JHU-029 993-D2 GDSC1 0.0391 10.0000
JHU-029 ABT737 GDSC2 0.0100 10.0000
JHU-029 Afatinib GDSC1,GDSC2 0.0020 10.0000
JHU-029 Afuresertib GDSC2 0.0100 10.0000
JHU-029 AGI-5198 GDSC2 0.0100 10.0000
JHU-029 AGI-6780 GDSC2 0.0100 10.0000
JHU-029 AGK-2 GDSC2 0.0040 4.0000
JHU-029 AICA Ribonucleotide GDSC1 7.8125 2000.0000
JHU-029 AKT inhibitor VIII GDSC1 0.0100 2.5600
JHU-029 Alisertib GDSC2 0.0100 10.0000
JHU-029 Alpelisib GDSC2 0.0100 10.0000
JHU-029 AMG-319 GDSC2 0.0100 10.0000
JHU-029 AS601245 GDSC1 0.0312 8.0000
JHU-029 AT13148 GDSC2 0.0080 8.0000
JHU-029 Avagacestat GDSC1,GDSC2 0.0100 10.0000
JHU-029 Axitinib GDSC1,GDSC2 0.0078 10.0000
JHU-029 AZ20 GDSC1 0.0391 10.0000
JHU-029 AZ6102 GDSC2 0.0100 10.0000
JHU-029 AZ960 GDSC2 0.0100 10.0000
JHU-029 AZD1208 GDSC1 0.0391 10.0000
JHU-029 AZD1332 GDSC1 0.0391 10.0000
JHU-029 AZD1480 GDSC1 0.0098 2.5000
JHU-029 AZD2014 GDSC1 0.0391 10.0000
JHU-029 AZD3514 GDSC1 0.0391 10.0000
JHU-029 AZD3759 GDSC2 0.0010 1.0000
JHU-029 AZD4547 GDSC1,GDSC2 0.0039 10.0000
JHU-029 AZD4877 GDSC1 0.0002 0.0390
JHU-029 AZD5363 GDSC2 0.0100 10.0000
JHU-029 AZD5438 GDSC1 0.0391 10.0000
JHU-029 AZD5582 GDSC1,GDSC2 0.0100 10.0000
JHU-029 AZD6094 GDSC1 0.0098 2.5000
JHU-029 AZD6482 GDSC1,GDSC2 0.0100 10.0000
JHU-029 AZD6738 GDSC1,GDSC2 0.0100 10.0000
JHU-029 AZD7762 GDSC1,GDSC2 0.0010 10.0000
JHU-029 AZD7969 GDSC1 0.0391 10.0000
JHU-029 AZD8055 GDSC1 0.0078 2.0000
JHU-029 AZD8186 GDSC1,GDSC2 0.0098 10.0000
JHU-029 AZD8835 GDSC1 0.0391 10.0000
JHU-029 AZD8931 GDSC1 0.0391 10.0000
JHU-029 BAY ACCi GDSC1 0.0391 10.0000
JHU-029 BAY AKT1 GDSC1 0.0391 10.0000
JHU-029 BAY-61-3606 GDSC1 0.0312 8.0000
JHU-029 BAY-HDAC11_1 GDSC1 0.0391 10.0000
JHU-029 BAY-HDAC11_2 GDSC1 0.0391 10.0000
JHU-029 BAY-HDAC11_4 GDSC1 0.0391 10.0000
JHU-029 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
JHU-029 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
JHU-029 BAY-MPS1 GDSC1 0.0117 3.0000
JHU-029 Bexarotene GDSC1 0.0312 8.0000
JHU-029 BI-2536 GDSC2 0.0005 0.5000
JHU-029 BIBR-1532 GDSC2 0.0100 10.0000
JHU-029 Bicalutamide GDSC1,GDSC2 0.0040 10.0000
JHU-029 Bleomycin GDSC1 0.2500 64.0000
JHU-029 Bleomycin (10 uM) GDSC1 0.0391 10.0000
JHU-029 Bleomycin (50 uM) GDSC1 0.1953 50.0000
JHU-029 BMS-345541 GDSC2 0.0100 10.0000
JHU-029 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
JHU-029 BMS-754807 GDSC1,GDSC2 0.0100 10.0000
JHU-029 Bortezomib GDSC2 0.0000 0.0200
JHU-029 Bosutinib GDSC1,GDSC2 0.0020 2.0000
JHU-029 BPTES GDSC1 0.0391 10.0000
JHU-029 Bryostatin 1 GDSC1 0.0000 0.0080
JHU-029 Buparlisib GDSC2 0.0100 10.0000
JHU-029 BX795 GDSC1,GDSC2 0.0100 10.0000
JHU-029 Camptothecin GDSC2 0.0001 0.1000
JHU-029 Capivasertib GDSC1 0.1172 30.0000
JHU-029 CCT-018159 GDSC1,GDSC2 0.0100 10.0000
JHU-029 CCT007093 GDSC1,GDSC2 0.0100 10.0000
JHU-029 CCT245232 GDSC1 0.0008 0.2000
JHU-029 CCT245467 GDSC1 0.0008 0.2000
JHU-029 Cediranib GDSC2 0.0100 10.0000
JHU-029 Cetuximab GDSC1 0.2570 65.8000
JHU-029 CHIR-99021 GDSC1,GDSC2 0.0100 10.0000
JHU-029 CI-1040 GDSC1 0.0391 10.0000
JHU-029 Cisplatin GDSC1 0.0117 10.0000
JHU-029 Crizotinib GDSC2 0.0040 8.0000
JHU-029 CRT0105446 GDSC1 0.0391 10.0000
JHU-029 CRT0105950 GDSC1 0.0391 10.0000
JHU-029 CRT0160829 GDSC1 0.0781 20.0000
JHU-029 Cyclophosphamide GDSC2 0.0100 10.0000
JHU-029 Cytarabine GDSC1 0.0078 2.0000
JHU-029 CZC24832 GDSC2 0.0100 10.0000
JHU-029 Dabrafenib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Dacinostat GDSC1 0.0040 1.0240
JHU-029 Dactinomycin GDSC2 0.0008 0.8000
JHU-029 Dactolisib GDSC1,GDSC2 0.0003 0.2500
JHU-029 Daporinad GDSC1,GDSC2 0.0010 1.0000
JHU-029 Dasatinib GDSC2 0.0020 2.0000
JHU-029 Dinaciclib GDSC2 0.0010 1.0000
JHU-029 DMOG GDSC1 15.6250 4000.0000
JHU-029 Docetaxel GDSC1,GDSC2 0.0000 0.0125
JHU-029 Doramapimod GDSC1,GDSC2 0.0100 10.0000
JHU-029 Doxorubicin GDSC1 0.0040 5.0000
JHU-029 Dyrk1b_0191 GDSC1 0.0391 10.0000
JHU-029 EHT-1864 GDSC1,GDSC2 0.0100 10.0000
JHU-029 Elesclomol GDSC1,GDSC2 0.0002 0.2000
JHU-029 Embelin GDSC1 0.1250 32.0000
JHU-029 Entinostat GDSC2 0.0100 10.0000
JHU-029 Entospletinib GDSC2 0.0100 10.0000
JHU-029 EphB4_9721 GDSC1 0.0391 10.0000
JHU-029 Epirubicin GDSC2 0.0100 10.0000
JHU-029 Epothilone B GDSC1 0.0001 0.0320
JHU-029 EPZ004777 GDSC2 0.0100 10.0000
JHU-029 EPZ5676 GDSC2 0.0100 10.0000
JHU-029 Erlotinib GDSC2 0.0100 10.0000
JHU-029 Etoposide GDSC1 0.0625 16.0000
JHU-029 FEN1_3940 GDSC1 0.0391 10.0000
JHU-029 FGFR_0939 GDSC1 0.0098 2.5000
JHU-029 FGFR_3831 GDSC1 0.0391 10.0000
JHU-029 FH535 GDSC1 0.1250 32.0000
JHU-029 Foretinib GDSC2 0.0100 10.0000
JHU-029 FS106 GDSC1 0.0391 10.0000
JHU-029 FS112 GDSC1 0.0195 5.0000
JHU-029 FTI-277 GDSC1 0.0040 1.0240
JHU-029 Fulvestrant GDSC1,GDSC2 0.0010 10.0000
JHU-029 FY012 GDSC1 0.0391 10.0000
JHU-029 FY026 GDSC1 0.0391 10.0000
JHU-029 FY069 GDSC1 0.0391 10.0000
JHU-029 GDC0810 GDSC2 0.0100 10.0000
JHU-029 Gefitinib GDSC1,GDSC2 0.0020 2.0000
JHU-029 Gemcitabine GDSC1,GDSC2 0.0002 10.0000
JHU-029 GNE-317 GDSC2 0.0100 10.0000
JHU-029 GSK-J4 GDSC1 0.1172 30.0000
JHU-029 GSK1904529A GDSC1,GDSC2 0.0040 5.0000
JHU-029 GSK2578215A GDSC2 0.0100 10.0000
JHU-029 GSK2606414 GDSC2 0.0100 10.0000
JHU-029 GSK269962A GDSC1,GDSC2 0.0100 10.0000
JHU-029 GSK343 GDSC2 0.0010 1.0000
JHU-029 GSK591 GDSC2 0.0100 10.0000
JHU-029 GSK650394 GDSC1 0.0625 16.0000
JHU-029 GW441756 GDSC1,GDSC2 0.0020 2.0000
JHU-029 HG-5-113-01 GDSC1 0.0391 10.0000
JHU-029 HG-5-88-01 GDSC1 0.0391 10.0000
JHU-029 HG6-64-1 GDSC1 0.0200 5.1200
JHU-029 I-BET-762 GDSC2 0.0100 10.0000
JHU-029 I-BET151 GDSC1 0.0391 10.0000
JHU-029 I-BRD9 GDSC2 0.0100 10.0000
JHU-029 I-CBP112 GDSC1 0.0391 10.0000
JHU-029 IAP_5620 GDSC1 0.0391 10.0000
JHU-029 IAP_7638 GDSC1 0.0391 10.0000
JHU-029 Ibrutinib GDSC2 0.0100 10.0000
JHU-029 ICL1100013 GDSC1 0.0781 20.0000
JHU-029 IGFR_3801 GDSC1 0.0391 10.0000
JHU-029 IOX2 GDSC1,GDSC2 0.0004 0.5000
JHU-029 IPA-3 GDSC1 0.1250 32.0000
JHU-029 Ipatasertib GDSC2 0.0100 10.0000
JHU-029 Irinotecan GDSC2 0.0050 5.0000
JHU-029 IWP-2 GDSC2 0.0010 1.0000
JHU-029 JAK1_3715 GDSC1 0.0391 10.0000
JHU-029 JAK3_7406 GDSC1 0.0391 10.0000
JHU-029 JNK Inhibitor VIII GDSC1,GDSC2 0.0100 10.0000
JHU-029 JNK-9L GDSC1 0.0200 5.1200
JHU-029 JQ1 GDSC1,GDSC2 0.0039 10.0000
JHU-029 JQ12 GDSC1 0.0200 5.1200
JHU-029 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
JHU-029 KU-55933 GDSC1,GDSC2 0.0100 10.0000
JHU-029 KU-60019 GDSC1 0.0391 10.0000
JHU-029 Lapatinib GDSC2 0.0100 10.0000
JHU-029 LCL161 GDSC2 0.0100 10.0000
JHU-029 Leflunomide GDSC2 0.1001 100.0000
JHU-029 Lenalidomide GDSC1,GDSC2 0.0100 10.0000
JHU-029 Lestaurtinib GDSC1,GDSC2 0.0020 2.0000
JHU-029 LFM-A13 GDSC1 0.0625 16.0000
JHU-029 LGK974 GDSC2 0.0100 10.0000
JHU-029 Linsitinib GDSC1,GDSC2 0.0100 10.0000
JHU-029 LJI308 GDSC2 0.0100 10.0000
JHU-029 Luminespib GDSC1,GDSC2 0.0003 0.2560
JHU-029 LY2109761 GDSC2 0.0050 5.0000
JHU-029 MCT1_6447 GDSC1 0.0391 10.0000
JHU-029 MCT4_1422 GDSC1 0.0391 10.0000
JHU-029 Methotrexate GDSC1,GDSC2 0.0008 1.0000
JHU-029 MG-132 GDSC2 0.0040 4.0000
JHU-029 Midostaurin GDSC1 0.0020 0.5120
JHU-029 MIRA-1 GDSC2 0.0100 10.0000
JHU-029 Mirin GDSC1,GDSC2 0.1001 100.0000
JHU-029 Mitomycin-C GDSC1 0.0625 16.0000
JHU-029 MK-1775 GDSC2 0.0100 10.0000
JHU-029 MK-2206 GDSC1,GDSC2 0.0100 10.0000
JHU-029 MK-8776 GDSC2 0.0050 5.0000
JHU-029 ML323 GDSC2 0.0200 20.0000
JHU-029 MN-64 GDSC2 0.0100 10.0000
JHU-029 Motesanib GDSC1,GDSC2 0.0078 10.0000
JHU-029 N22899-6-C1 GDSC1 0.0391 10.0000
JHU-029 N23918-95-7 GDSC1 0.0391 10.0000
JHU-029 N24798-49-A1 GDSC1 0.0391 10.0000
JHU-029 Navitoclax GDSC1,GDSC2 0.0020 2.0000
JHU-029 Nilotinib GDSC1,GDSC2 0.0078 10.0000
JHU-029 Niraparib GDSC2 0.0100 10.0000
JHU-029 NSC-87877 GDSC1 0.0625 16.0000
JHU-029 NU7441 GDSC1,GDSC2 0.0078 10.0000
JHU-029 Nutlin-3a GDSC1,GDSC2 0.0100 10.0000
JHU-029 NVP-ADW742 GDSC2 0.0100 10.0000
JHU-029 Obatoclax Mesylate GDSC1 0.0625 16.0000
JHU-029 OF-1 GDSC2 0.0100 10.0000
JHU-029 Olaparib GDSC1,GDSC2 0.0100 10.0000
JHU-029 OSI-027 GDSC2 0.0100 10.0000
JHU-029 Osimertinib GDSC2 0.0010 1.0000
JHU-029 OSU-03012 GDSC1 0.0625 16.0000
JHU-029 OTX015 GDSC2 0.0100 10.0000
JHU-029 Oxaliplatin GDSC2 0.0100 10.0000
JHU-029 P22077 GDSC2 0.0100 10.0000
JHU-029 PAC-1 GDSC1 0.0100 2.5600
JHU-029 Paclitaxel GDSC2 0.0001 0.1000
JHU-029 Palbociclib GDSC1,GDSC2 0.0040 4.0000
JHU-029 PARP_0108 GDSC1 0.0098 2.5000
JHU-029 PARP_9482 GDSC1 0.0098 2.5000
JHU-029 PARP_9495 GDSC1 0.0098 2.5000
JHU-029 Pazopanib GDSC1 0.0312 8.0000
JHU-029 PCI-34051 GDSC2 0.0100 10.0000
JHU-029 PD0325901 GDSC1,GDSC2 0.0010 2.5000
JHU-029 PD173074 GDSC1,GDSC2 0.0078 10.0000
JHU-029 Pevonedistat GDSC1,GDSC2 0.0039 10.0000
JHU-029 PF-4708671 GDSC1,GDSC2 0.0100 10.0000
JHU-029 PF-562271 GDSC1 0.0100 2.5600
JHU-029 PFI-1 GDSC1,GDSC2 0.0100 10.0000
JHU-029 PFI3 GDSC1,GDSC2 0.0100 10.0000
JHU-029 PI3Ka_4409 GDSC1 0.0391 10.0000
JHU-029 Picolinici-acid GDSC2 0.0100 10.0000
JHU-029 Pictilisib GDSC1,GDSC2 0.0040 4.0000
JHU-029 Piperlongumine GDSC1,GDSC2 0.0100 10.0000
JHU-029 PLK_6522 GDSC1 0.0024 0.6250
JHU-029 PLX-4720 GDSC1,GDSC2 0.0100 10.0000
JHU-029 Ponatinib GDSC1 0.0020 0.5120
JHU-029 PRIMA-1MET GDSC2 0.0300 30.0000
JHU-029 PRT062607 GDSC2 0.0100 10.0000
JHU-029 Pyridostatin GDSC2 0.0100 10.0000
JHU-029 QL-VIII-58 GDSC1 0.0391 10.0000
JHU-029 QL-XII-61 GDSC1 0.0391 10.0000
JHU-029 QS11 GDSC1 0.0400 10.2400
JHU-029 RAF_9304 GDSC1 0.0391 10.0000
JHU-029 Rapamycin GDSC2 0.0001 0.1000
JHU-029 Refametinib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Ribociclib GDSC2 0.0020 2.0000
JHU-029 RO-3306 GDSC1,GDSC2 0.0100 10.0000
JHU-029 rTRAIL GDSC1 0.0004 0.1000
JHU-029 Rucaparib GDSC1,GDSC2 0.0050 5.0000
JHU-029 Ruxolitinib GDSC2 0.0100 10.0000
JHU-029 RVX-208 GDSC2 0.0100 10.0000
JHU-029 Sabutoclax GDSC2 0.0100 10.0000
JHU-029 Sapitinib GDSC2 0.0050 5.0000
JHU-029 Savolitinib GDSC2 0.0010 1.0000
JHU-029 SB216763 GDSC1,GDSC2 0.0100 10.0000
JHU-029 SB505124 GDSC1,GDSC2 0.0100 10.0000
JHU-029 SB590885 GDSC1,GDSC2 0.0050 5.0000
JHU-029 SCH772984 GDSC2 0.0050 5.0000
JHU-029 Selumetinib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Sepantronium bromide GDSC2 0.0100 10.0000
JHU-029 Serdemetan GDSC1,GDSC2 0.0100 10.0000
JHU-029 SGC0946 GDSC1,GDSC2 0.0005 0.5000
JHU-029 Shikonin GDSC1 0.0625 16.0000
JHU-029 SL0101 GDSC1,GDSC2 0.0100 10.0000
JHU-029 SN-38 GDSC1,GDSC2 0.0002 10.0000
JHU-029 Sorafenib GDSC2 0.0100 10.0000
JHU-029 Staurosporine GDSC2 0.0078 2.0000
JHU-029 Talazoparib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Tamoxifen GDSC1,GDSC2 0.0100 10.0000
JHU-029 Tanespimycin GDSC1,GDSC2 0.0010 1.0000
JHU-029 TANK_1366 GDSC1 0.0098 2.5000
JHU-029 Taselisib GDSC2 0.0100 10.0000
JHU-029 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
JHU-029 Temozolomide GDSC1,GDSC2 0.0300 30.0000
JHU-029 Temsirolimus GDSC1,GDSC2 0.0008 1.0000
JHU-029 Thapsigargin GDSC1 0.0020 0.5120
JHU-029 Tipifarnib GDSC1 0.0625 16.0000
JHU-029 Tozasertib GDSC2 0.0050 5.0000
JHU-029 Trametinib GDSC1,GDSC2 0.0010 1.0000
JHU-029 Tretinoin GDSC1,GDSC2 0.0100 10.0000
JHU-029 TTK_3146 GDSC1 0.0391 10.0000
JHU-029 TW 37 GDSC1 0.0195 5.0000
JHU-029 Ulixertinib GDSC2 0.0100 10.0000
JHU-029 UNC0638 GDSC1 0.0781 20.0000
JHU-029 UNC0642 GDSC1 0.0020 0.5000
JHU-029 UNC1215 GDSC1 0.0039 1.0000
JHU-029 Uprosertib GDSC2 0.0100 10.0000
JHU-029 VE-822 GDSC2 0.0050 5.0000
JHU-029 VE821 GDSC2 0.0100 10.0000
JHU-029 Veliparib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Venetoclax GDSC2 0.0010 1.0000
JHU-029 Vinblastine GDSC1 0.0004 0.1000
JHU-029 Vinorelbine GDSC1,GDSC2 0.0001 0.1000
JHU-029 Vismodegib GDSC1,GDSC2 0.0100 10.0000
JHU-029 Vorinostat GDSC1,GDSC2 0.0100 10.0000
JHU-029 VX-11e GDSC2 0.0100 10.0000
JHU-029 VX-702 GDSC1 0.0078 2.0000
JHU-029 Wee1 Inhibitor GDSC1,GDSC2 0.0078 10.0000
JHU-029 WEHI-539 GDSC2 0.0100 10.0000
JHU-029 WIKI4 GDSC2 0.0100 10.0000
JHU-029 Wnt-C59 GDSC2 0.0100 10.0000
JHU-029 WZ4003 GDSC2 0.0100 10.0000
JHU-029 XAV939 GDSC1,GDSC2 0.0050 5.0000
JHU-029 XMD11-85h GDSC1 0.0391 10.0000
JHU-029 XMD8-92 GDSC1 0.0391 10.0000
JHU-029 YK-4-279 GDSC1,GDSC2 0.0100 10.0000
JHU-029 ZG-10 GDSC1 0.0391 10.0000
JHU-029 ZL049 GDSC1 0.0391 10.0000
JHU-029 ZL109 GDSC1 0.0391 10.0000
JHU-029 ZM447439 GDSC1,GDSC2 0.0100 10.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC