Cell Line : TOLEDO

Cellosaurus Index : CVCL_3611
Cellosaurus ID : TOLEDO

CCLE Name : TOLEDO_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CTRP2 Name : TOLEDO

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
TOLEDO 1S,3R-RSL-3 CTRP2 0.0010 17.0000
TOLEDO 3-Cl-AHPC CTRP2 0.0020 66.0000
TOLEDO AA-COCF3 CTRP2 0.0010 33.0000
TOLEDO ABT737 CTRP2 0.0011 37.0000
TOLEDO AC55649 CTRP2 0.0010 33.0000
TOLEDO AEW541 CCLE 0.0025 8.0000
TOLEDO Afatinib CTRP2 0.0020 66.0000
TOLEDO AGK-2 CTRP2 0.0010 33.0000
TOLEDO Alisertib CTRP2 0.0020 66.0000
TOLEDO alisertib:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO Alpelisib CTRP2 0.0020 66.0000
TOLEDO alvocidib CTRP2 0.0020 66.0000
TOLEDO AM-580 CTRP2 0.0160 530.0000
TOLEDO apicidin CTRP2 0.0010 33.0000
TOLEDO AT7867 CTRP2 0.0020 66.0000
TOLEDO austocystin D CTRP2 0.0011 37.0000
TOLEDO avrainvillamide CTRP2 0.0010 33.0000
TOLEDO Axitinib CTRP2 0.0020 66.0000
TOLEDO AZ-3146 CTRP2 0.0020 66.0000
TOLEDO AZD-7545 CTRP2 0.0023 74.0000
TOLEDO AZD4547 CTRP2 0.0020 66.0000
TOLEDO AZD6482 CTRP2 0.0020 66.0000
TOLEDO AZD8055 CTRP2 0.0020 33.0000
TOLEDO B02 CTRP2 0.0041 130.0000
TOLEDO barasertib CTRP2 0.0020 66.0000
TOLEDO BCL-LZH-4 CTRP2 0.0020 66.0000
TOLEDO Belinostat CTRP2 0.0020 66.0000
TOLEDO bendamustine CTRP2 0.0020 66.0000
TOLEDO BI-2536 CTRP2 0.0010 33.0000
TOLEDO BIBR-1532 CTRP2 0.0081 270.0000
TOLEDO birinapant CTRP2 0.0020 66.0000
TOLEDO BIX-01294 CTRP2 0.0010 33.0000
TOLEDO bleomycin A2 CTRP2 0.0020 66.0000
TOLEDO BMS-270394 CTRP2 0.0020 66.0000
TOLEDO BMS-345541 CTRP2 0.0020 66.0000
TOLEDO BMS-754807 CTRP2 0.0010 33.0000
TOLEDO Bosutinib CTRP2 0.0020 66.0000
TOLEDO BRD-A02303741:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
TOLEDO BRD-A02303741:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO BRD-A71883111 CTRP2 0.0010 33.0000
TOLEDO BRD-A86708339 CTRP2 0.0020 66.0000
TOLEDO BRD-K02251932 CTRP2 0.0020 66.0000
TOLEDO BRD-K07442505 CTRP2 0.0020 66.0000
TOLEDO BRD-K09587429 CTRP2 0.0020 66.0000
TOLEDO BRD-K11533227 CTRP2 0.0020 66.0000
TOLEDO BRD-K14844214 CTRP2 0.0020 66.0000
TOLEDO BRD-K16147474 CTRP2 0.0020 66.0000
TOLEDO BRD-K17060750 CTRP2 0.0020 66.0000
TOLEDO BRD-K24690302 CTRP2 0.0020 66.0000
TOLEDO BRD-K26531177 CTRP2 0.0100 330.0000
TOLEDO BRD-K29313308 CTRP2 0.0020 66.0000
TOLEDO BRD-K34222889 CTRP2 0.0017 57.0000
TOLEDO BRD-K37390332 CTRP2 0.0010 33.0000
TOLEDO BRD-K41597374 CTRP2 0.0020 66.0000
TOLEDO BRD-K45681478 CTRP2 0.0020 66.0000
TOLEDO BRD-K50799972 CTRP2 0.0020 17.0000
TOLEDO BRD-K51490254 CTRP2 0.0020 66.0000
TOLEDO BRD-K52037352 CTRP2 0.0020 66.0000
TOLEDO BRD-K63431240 CTRP2 0.0020 66.0000
TOLEDO BRD-K66532283 CTRP2 0.0020 66.0000
TOLEDO BRD-K71935468 CTRP2 0.0025 83.0000
TOLEDO BRD-K90370028 CTRP2 0.0010 33.0000
TOLEDO BRD-K94991378 CTRP2 0.0025 83.0000
TOLEDO BRD-K99006945 CTRP2 0.0020 66.0000
TOLEDO BRD-M00053801 CTRP2 0.0020 66.0000
TOLEDO BRD55319 CTRP2 0.0011 37.0000
TOLEDO BRD6340 CTRP2 0.0010 33.0000
TOLEDO BRD6430 CTRP2 0.0010 33.0000
TOLEDO BRD8899 CTRP2 0.0020 33.0000
TOLEDO BRD9647 CTRP2 0.0010 33.0000
TOLEDO BRD9876 CTRP2 0.0041 130.0000
TOLEDO Cabozantinib CTRP2 0.0020 66.0000
TOLEDO canertinib CTRP2 0.0020 66.0000
TOLEDO Carboplatin CTRP2 0.0020 66.0000
TOLEDO carboplatin:etoposide (40:17 mol-mol) CTRP2 0.0014 47.0000
TOLEDO carboplatin:UNC0638 (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO CAY10576 CTRP2 0.0020 66.0000
TOLEDO CAY10618 CTRP2 0.0010 33.0000
TOLEDO CBB-1007 CTRP2 0.0020 66.0000
TOLEDO CD-437 CTRP2 0.0011 37.0000
TOLEDO Cediranib CTRP2 0.0020 66.0000
TOLEDO ceranib-2 CTRP2 0.0020 66.0000
TOLEDO cerulenin CTRP2 0.0045 150.0000
TOLEDO CHEMBL1222381 CTRP2 0.0081 270.0000
TOLEDO CHIR-99021 CTRP2 0.0024 80.0000
TOLEDO CHM-1 CTRP2 0.0005 16.0000
TOLEDO CI-976 CTRP2 0.0081 270.0000
TOLEDO ciclosporin CTRP2 0.0010 33.0000
TOLEDO CID-5951923 CTRP2 0.0020 66.0000
TOLEDO clofarabine CTRP2 0.0020 66.0000
TOLEDO COL-3 CTRP2 0.0020 66.0000
TOLEDO compound 1B CTRP2 0.0020 66.0000
TOLEDO Compound 23 citrate CTRP2 0.0010 33.0000
TOLEDO Compound 7d-cis CTRP2 0.0010 33.0000
TOLEDO CR-1-31B CTRP2 0.0010 33.0000
TOLEDO Crizotinib CCLE 0.0025 8.0000
TOLEDO cucurbitacin I CTRP2 0.0010 33.0000
TOLEDO curcumin CTRP2 0.0051 170.0000
TOLEDO cytochalasin B CTRP2 0.0010 33.0000
TOLEDO Dabrafenib CTRP2 0.0020 66.0000
TOLEDO Dactolisib CTRP2 0.0005 17.0000
TOLEDO Daporinad CTRP2 0.0001 2.0000
TOLEDO Dasatinib CTRP2 0.0020 66.0000
TOLEDO DBeQ CTRP2 0.0020 66.0000
TOLEDO Decitabine CTRP2 0.0020 66.0000
TOLEDO decitabine:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
TOLEDO decitabine:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO dexamethasone CTRP2 0.0010 33.0000
TOLEDO Dinaciclib CTRP2 0.0020 66.0000
TOLEDO Docetaxel CTRP2 0.0020 66.0000
TOLEDO docetaxel:tanespimycin (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO Doxorubicin CTRP2 0.0020 66.0000
TOLEDO doxorubicin:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO elocalcitol CTRP2 0.0020 66.0000
TOLEDO Entinostat CTRP2 0.0020 66.0000
TOLEDO epigallocatechin-3-monogallate CTRP2 0.0090 300.0000
TOLEDO erastin CTRP2 0.0020 66.0000
TOLEDO Erlotinib CCLE 0.0025 8.0000
TOLEDO etomoxir CTRP2 0.0090 300.0000
TOLEDO Etoposide CTRP2 0.0009 28.0000
TOLEDO fingolimod CTRP2 0.0020 66.0000
TOLEDO Foretinib CTRP2 0.0020 66.0000
TOLEDO FQI-2 CTRP2 0.0010 17.0000
TOLEDO fumonisin B1 CTRP2 0.0150 500.0000
TOLEDO GANT-61 CTRP2 0.0020 66.0000
TOLEDO GDC-0879 CTRP2 0.0020 66.0000
TOLEDO GMX-1778 CTRP2 0.0000 0.3000
TOLEDO GSK1059615 CTRP2 0.0010 33.0000
TOLEDO GSK4112 CTRP2 0.0020 66.0000
TOLEDO GW-405833 CTRP2 0.0041 130.0000
TOLEDO HBX-41108 CTRP2 0.0020 66.0000
TOLEDO HC-067047 CTRP2 0.0020 66.0000
TOLEDO I-BET-762 CTRP2 0.0020 66.0000
TOLEDO I-BET151 CTRP2 0.0020 66.0000
TOLEDO Ibrutinib CTRP2 0.0020 66.0000
TOLEDO IC-87114 CTRP2 0.0020 66.0000
TOLEDO Idelalisib CTRP2 0.0020 66.0000
TOLEDO importazole CTRP2 0.0061 200.0000
TOLEDO indisulam CTRP2 0.0010 33.0000
TOLEDO isoevodiamine CTRP2 0.0010 33.0000
TOLEDO ISOX CTRP2 0.0010 33.0000
TOLEDO istradefylline CTRP2 0.0010 33.0000
TOLEDO JQ-1:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
TOLEDO JQ-1:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO JW-74 CTRP2 0.0020 66.0000
TOLEDO KHS101 CTRP2 0.0020 66.0000
TOLEDO KPT185 CTRP2 0.0020 66.0000
TOLEDO KU-0063794 CTRP2 0.0020 66.0000
TOLEDO KU-60019 CTRP2 0.0020 66.0000
TOLEDO KW-2449 CTRP2 0.0020 66.0000
TOLEDO L-685458 CTRP2,CCLE 0.0011 37.0000
TOLEDO Lapatinib CCLE 0.0025 8.0000
TOLEDO LBW242 CCLE 0.0025 8.0000
TOLEDO LE-135 CTRP2 0.0020 66.0000
TOLEDO Lenvatinib CTRP2 0.0020 66.0000
TOLEDO leptomycin B CTRP2 0.0020 66.0000
TOLEDO Linifanib CTRP2 0.0020 66.0000
TOLEDO Linsitinib CTRP2 0.0010 33.0000
TOLEDO lomeguatrib CTRP2 0.0020 66.0000
TOLEDO lovastatin acid CTRP2 0.0041 130.0000
TOLEDO LY-2183240 CTRP2 0.0010 33.0000
TOLEDO manumycin A CTRP2 0.0009 30.0000
TOLEDO Mdivi-1 CTRP2 0.0020 66.0000
TOLEDO Merck60 CTRP2 0.0010 33.0000
TOLEDO Methotrexate CTRP2 0.0020 66.0000
TOLEDO MG-132 CTRP2 0.0006 20.0000
TOLEDO MI-1 CTRP2 0.0010 33.0000
TOLEDO MI-2 CTRP2 0.0020 66.0000
TOLEDO MIRA-1 CTRP2 0.0020 33.0000
TOLEDO MK-1775 CTRP2 0.0010 33.0000
TOLEDO ML006 CTRP2 0.0160 530.0000
TOLEDO ML030 CTRP2 0.0020 66.0000
TOLEDO ML162 CTRP2 0.0010 33.0000
TOLEDO ML210 CTRP2 0.0010 33.0000
TOLEDO ML239 CTRP2 0.0020 66.0000
TOLEDO ML258 CTRP2 0.0020 66.0000
TOLEDO ML311 CTRP2 0.0010 66.0000
TOLEDO ML320 CTRP2 0.0020 66.0000
TOLEDO MLN2480 CTRP2 0.0020 66.0000
TOLEDO momelotinib CTRP2 0.0020 66.0000
TOLEDO myricetin CTRP2 0.0020 66.0000
TOLEDO N9-isopropylolomoucine CTRP2 0.0120 400.0000
TOLEDO narciclasine CTRP2 0.0010 33.0000
TOLEDO Navitoclax CTRP2 0.0010 33.0000
TOLEDO navitoclax:birinapant (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:gemcitabine (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:piperlongumine (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:pluripotin (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:PLX-4032 (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO navitoclax:sorafenib (1:1 mol-mol) CTRP2 0.0015 50.0000
TOLEDO necrostatin-7 CTRP2 0.0020 66.0000
TOLEDO necrosulfonamide CTRP2 0.0020 66.0000
TOLEDO neratinib CTRP2 0.0010 33.0000
TOLEDO niclosamide CTRP2 0.0010 33.0000
TOLEDO Nilotinib CTRP2,CCLE 0.0020 66.0000
TOLEDO NSC 74859 CTRP2 0.0160 530.0000
TOLEDO NSC30930 CTRP2 0.0020 66.0000
TOLEDO NSC48300 CTRP2 0.0020 66.0000
TOLEDO NSC632839 CTRP2 0.0010 33.0000
TOLEDO Nutlin-3a CTRP2,CCLE 0.0025 150.0000
TOLEDO NVP-231 CTRP2 0.0020 66.0000
TOLEDO NVP-TAE684 CTRP2,CCLE 0.0020 66.0000
TOLEDO O-6-benzylguanine CTRP2 0.0020 66.0000
TOLEDO Olaparib CTRP2 0.0045 150.0000
TOLEDO oligomycin A CTRP2 0.0010 33.0000
TOLEDO omacetaxine mepesuccinate CTRP2 0.0020 66.0000
TOLEDO OSI-027 CTRP2 0.0020 66.0000
TOLEDO ouabain CTRP2 0.0081 270.0000
TOLEDO Oxaliplatin CTRP2 0.0020 66.0000
TOLEDO Paclitaxel CTRP2,CCLE 0.0020 66.0000
TOLEDO Palbociclib CCLE 0.0025 8.0000
TOLEDO Panobinostat CCLE 0.0025 8.0000
TOLEDO parbendazole CTRP2 0.0020 66.0000
TOLEDO Parthenolide CTRP2 0.0020 66.0000
TOLEDO PD0325901 CCLE 0.0025 8.0000
TOLEDO PD318088 CTRP2 0.0020 66.0000
TOLEDO PDMP CTRP2 0.0065 210.0000
TOLEDO Pevonedistat CTRP2 0.0011 37.0000
TOLEDO PF-3758309 CTRP2 0.0020 66.0000
TOLEDO PF-4800567 hydrochloride CTRP2 0.0020 66.0000
TOLEDO PF-573228 CTRP2 0.0020 66.0000
TOLEDO PF-750 CTRP2 0.0081 270.0000
TOLEDO PHA-665752 CCLE 0.0025 8.0000
TOLEDO PHA-793887 CTRP2 0.0020 66.0000
TOLEDO PI-103 CTRP2 0.0011 37.0000
TOLEDO Pictilisib CTRP2 0.0020 66.0000
TOLEDO pifithrin-alpha CTRP2 0.0071 230.0000
TOLEDO pifithrin-mu CTRP2 0.0010 33.0000
TOLEDO Piperlongumine CTRP2 0.0010 33.0000
TOLEDO piperlongumine:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO Platin CTRP2 0.0020 66.0000
TOLEDO pluripotin CTRP2 0.0010 33.0000
TOLEDO PLX-4720 CTRP2,CCLE 0.0010 33.0000
TOLEDO procarbazine CTRP2 0.0020 66.0000
TOLEDO pyrazolanthrone CTRP2 0.0020 66.0000
TOLEDO R428 CTRP2 0.0020 66.0000
TOLEDO RAF265 CCLE 0.0025 8.0000
TOLEDO Rapamycin CTRP2 0.0010 33.0000
TOLEDO Regorafenib CTRP2 0.0020 66.0000
TOLEDO RG-108 CTRP2 0.0081 270.0000
TOLEDO RITA CTRP2 0.0010 33.0000
TOLEDO RO4929097 CTRP2 0.0020 66.0000
TOLEDO Ruxolitinib CTRP2 0.0020 66.0000
TOLEDO Saracatinib CTRP2,CCLE 0.0020 66.0000
TOLEDO SB-225002 CTRP2 0.0011 37.0000
TOLEDO SB-525334 CTRP2 0.0020 66.0000
TOLEDO SB-743921 CTRP2 0.0010 33.0000
TOLEDO SCH-529074 CTRP2 0.0010 33.0000
TOLEDO SCH-79797 CTRP2 0.0011 37.0000
TOLEDO Selumetinib CTRP2,CCLE 0.0025 270.0000
TOLEDO selumetinib:BRD-A02303741 (4:1 mol-mol) CTRP2 0.0051 170.0000
TOLEDO selumetinib:JQ-1 (4:1 mol-mol) CTRP2 0.0051 170.0000
TOLEDO selumetinib:MK-2206 (8:1 mol-mol) CTRP2 0.0046 150.0000
TOLEDO selumetinib:PLX-4032 (8:1 mol-mol) CTRP2 0.0046 150.0000
TOLEDO selumetinib:tretinoin (2:1 mol-mol) CTRP2 0.0061 200.0000
TOLEDO selumetinib:UNC0638 (4:1 mol-mol) CTRP2 0.0051 170.0000
TOLEDO semagacestat CTRP2 0.0020 66.0000
TOLEDO Sepantronium bromide CTRP2 0.0000 1.0000
TOLEDO Serdemetan CTRP2 0.0010 33.0000
TOLEDO serdemetan:SCH-529074 (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO SGX-523 CTRP2 0.0020 66.0000
TOLEDO simvastatin CTRP2 0.0010 33.0000
TOLEDO sirolimus:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
TOLEDO skepinone-L CTRP2 0.0020 66.0000
TOLEDO SN-38 CTRP2 0.0000 1.3000
TOLEDO SNX-2112:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
TOLEDO Sorafenib CTRP2,CCLE 0.0020 66.0000
TOLEDO sotrastaurin CTRP2 0.0020 66.0000
TOLEDO spautin-1 CTRP2 0.0020 66.0000
TOLEDO Sphingosine Kinase 1 Inhibitor II CTRP2 0.0010 33.0000
TOLEDO SR-II-138A CTRP2 0.0010 33.0000
TOLEDO STF-31 CTRP2 0.0020 66.0000
TOLEDO SU11274 CTRP2 0.0020 66.0000
TOLEDO SZ4TA2 CTRP2 0.0020 66.0000
TOLEDO T-5345967 CTRP2 0.0160 530.0000
TOLEDO tacedinaline CTRP2 0.0010 33.0000
TOLEDO tamatinib CTRP2 0.0010 33.0000
TOLEDO Tamoxifen CTRP2 0.0030 100.0000
TOLEDO Tanespimycin CTRP2,CCLE 0.0010 33.0000
TOLEDO Telomerase Inhibitor IX CTRP2 0.0010 33.0000
TOLEDO Temozolomide CTRP2 0.0020 66.0000
TOLEDO TG-100-115 CTRP2 0.0020 66.0000
TOLEDO TGX221 CTRP2 0.0020 66.0000
TOLEDO Thalidomide CTRP2 0.0020 66.0000
TOLEDO tivantinib CTRP2 0.0020 66.0000
TOLEDO TKI258 CCLE 0.0025 8.0000
TOLEDO Topotecan CTRP2,CCLE 0.0020 66.0000
TOLEDO tosedostat CTRP2 0.0081 270.0000
TOLEDO TPCA-1 CTRP2 0.0020 66.0000
TOLEDO Trametinib CTRP2 0.0020 66.0000
TOLEDO Tretinoin CTRP2 0.0041 130.0000
TOLEDO tretinoin:carboplatin (2:1 mol-mol) CTRP2 0.0030 100.0000
TOLEDO tretinoin:navitoclax (4:1 mol-mol) CTRP2 0.0025 83.0000
TOLEDO triptolide CTRP2 0.0000 0.3000
TOLEDO TW 37 CTRP2 0.0010 33.0000
TOLEDO UNC0321 CTRP2 0.0010 33.0000
TOLEDO UNC0638 CTRP2 0.0010 17.0000
TOLEDO UNC0638:navitoclax (1:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO valdecoxib CTRP2 0.0180 600.0000
TOLEDO vandetanib CTRP2 0.0020 66.0000
TOLEDO Veliparib CTRP2 0.0010 33.0000
TOLEDO Venetoclax CTRP2 0.0020 66.0000
TOLEDO VER-155008 CTRP2 0.0011 37.0000
TOLEDO Vincristine CTRP2 0.0041 130.0000
TOLEDO Vorinostat CTRP2 0.0010 33.0000
TOLEDO vorinostat:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
TOLEDO vorinostat:navitoclax (4:1 mol-mol) CTRP2 0.0010 33.0000
TOLEDO VU0155056 CTRP2 0.0020 66.0000
TOLEDO WAY-362450 CTRP2 0.0020 66.0000
TOLEDO WP1130 CTRP2 0.0020 66.0000
TOLEDO XL765 CTRP2 0.0020 66.0000
TOLEDO YK-4-279 CTRP2 0.0010 33.0000
TOLEDO ZD-6474 CCLE 0.0025 8.0000
TOLEDO zebularine CTRP2 0.0180 590.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC