Cell Line : SUP-B8

Cellosaurus Index : CVCL_1713
Cellosaurus ID : SUP-B8

CCLE Name : SUPB8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
GDSC1 Name , GDSC2 Name : SUP-B8

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
SUP-B8 (5Z)-7-Oxozeaenol GDSC1 0.0391 10.0000
SUP-B8 5-Fluorouracil GDSC2 0.0200 20.0000
SUP-B8 965-D2 GDSC1 0.0391 10.0000
SUP-B8 993-D2 GDSC1 0.0391 10.0000
SUP-B8 ABT737 GDSC2 0.0100 10.0000
SUP-B8 Afatinib GDSC1,GDSC2 0.0020 10.0000
SUP-B8 Afuresertib GDSC2 0.0100 10.0000
SUP-B8 AGI-5198 GDSC2 0.0100 10.0000
SUP-B8 AGI-6780 GDSC2 0.0100 10.0000
SUP-B8 AGK-2 GDSC2 0.0040 4.0000
SUP-B8 AICA Ribonucleotide GDSC1 7.8125 2000.0000
SUP-B8 Alisertib GDSC2 0.0100 10.0000
SUP-B8 Alpelisib GDSC2 0.0100 10.0000
SUP-B8 AMG-319 GDSC2 0.0100 10.0000
SUP-B8 AT13148 GDSC2 0.0080 8.0000
SUP-B8 Avagacestat GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Axitinib GDSC1,GDSC2 0.0078 10.0000
SUP-B8 AZ20 GDSC1 0.0391 10.0000
SUP-B8 AZ6102 GDSC2 0.0100 10.0000
SUP-B8 AZ960 GDSC2 0.0100 10.0000
SUP-B8 AZD1208 GDSC1 0.0391 10.0000
SUP-B8 AZD1332 GDSC1 0.0391 10.0000
SUP-B8 AZD1480 GDSC1 0.0098 2.5000
SUP-B8 AZD2014 GDSC1 0.0391 10.0000
SUP-B8 AZD3514 GDSC1 0.0391 10.0000
SUP-B8 AZD3759 GDSC2 0.0010 1.0000
SUP-B8 AZD4547 GDSC1,GDSC2 0.0039 10.0000
SUP-B8 AZD4877 GDSC1 0.0002 0.0390
SUP-B8 AZD5363 GDSC2 0.0100 10.0000
SUP-B8 AZD5438 GDSC1 0.0391 10.0000
SUP-B8 AZD5582 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 AZD6094 GDSC1 0.0098 2.5000
SUP-B8 AZD6482 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 AZD6738 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 AZD7762 GDSC1,GDSC2 0.0010 10.0000
SUP-B8 AZD7969 GDSC1 0.0391 10.0000
SUP-B8 AZD8055 GDSC1 0.0078 2.0000
SUP-B8 AZD8186 GDSC1,GDSC2 0.0098 10.0000
SUP-B8 AZD8835 GDSC1 0.0391 10.0000
SUP-B8 AZD8931 GDSC1 0.0391 10.0000
SUP-B8 BAY ACCi GDSC1 0.0391 10.0000
SUP-B8 BAY AKT1 GDSC1 0.0391 10.0000
SUP-B8 BAY-HDAC11_1 GDSC1 0.0391 10.0000
SUP-B8 BAY-HDAC11_2 GDSC1 0.0391 10.0000
SUP-B8 BAY-HDAC11_4 GDSC1 0.0391 10.0000
SUP-B8 BAY-MPS-combo 2 (paclitaxel 1 uM) GDSC1 0.0039 1.0000
SUP-B8 BAY-MPS-combo-1 (paclitaxel 5 uM) GDSC1 0.0039 1.0000
SUP-B8 BAY-MPS1 GDSC1 0.0117 3.0000
SUP-B8 BI-2536 GDSC2 0.0005 0.5000
SUP-B8 BIBR-1532 GDSC2 0.0100 10.0000
SUP-B8 Bicalutamide GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Bleomycin (10 uM) GDSC1 0.0391 10.0000
SUP-B8 Bleomycin (50 uM) GDSC1 0.1953 50.0000
SUP-B8 BMS-345541 GDSC2 0.0100 10.0000
SUP-B8 BMS-536924 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 BMS-754807 GDSC2 0.0100 10.0000
SUP-B8 Bortezomib GDSC2 0.0000 0.0200
SUP-B8 Bosutinib GDSC1,GDSC2 0.0020 2.0000
SUP-B8 BPTES GDSC1 0.0391 10.0000
SUP-B8 Buparlisib GDSC2 0.0100 10.0000
SUP-B8 BX795 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Camptothecin GDSC2 0.0001 0.1000
SUP-B8 Capivasertib GDSC1 0.1172 30.0000
SUP-B8 CCT-018159 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 CCT007093 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 CCT245232 GDSC1 0.0008 0.2000
SUP-B8 CCT245467 GDSC1 0.0008 0.2000
SUP-B8 Cediranib GDSC2 0.0100 10.0000
SUP-B8 Cetuximab GDSC1 0.2570 65.8000
SUP-B8 CHIR-99021 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 CI-1040 GDSC1 0.0391 10.0000
SUP-B8 Cisplatin GDSC1 0.0117 10.0000
SUP-B8 Crizotinib GDSC2 0.0040 8.0000
SUP-B8 CRT0105446 GDSC1 0.0391 10.0000
SUP-B8 CRT0105950 GDSC1 0.0391 10.0000
SUP-B8 CRT0160829 GDSC1 0.0781 20.0000
SUP-B8 Cyclophosphamide GDSC2 0.0100 10.0000
SUP-B8 Cytarabine GDSC1 0.0078 2.0000
SUP-B8 CZC24832 GDSC2 0.0100 10.0000
SUP-B8 Dabrafenib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Dactinomycin GDSC2 0.0008 0.8000
SUP-B8 Dactolisib GDSC1,GDSC2 0.0003 0.2500
SUP-B8 Daporinad GDSC1,GDSC2 0.0010 1.0000
SUP-B8 Dasatinib GDSC2 0.0020 2.0000
SUP-B8 Dinaciclib GDSC2 0.0010 1.0000
SUP-B8 Docetaxel GDSC1,GDSC2 0.0000 0.0125
SUP-B8 Doramapimod GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Doxorubicin GDSC1 0.0195 5.0000
SUP-B8 Dyrk1b_0191 GDSC1 0.0391 10.0000
SUP-B8 EHT-1864 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Elesclomol GDSC1,GDSC2 0.0002 0.2000
SUP-B8 Entinostat GDSC2 0.0100 10.0000
SUP-B8 Entospletinib GDSC2 0.0100 10.0000
SUP-B8 EphB4_9721 GDSC1 0.0391 10.0000
SUP-B8 Epirubicin GDSC2 0.0100 10.0000
SUP-B8 EPZ004777 GDSC2 0.0100 10.0000
SUP-B8 EPZ5676 GDSC2 0.0100 10.0000
SUP-B8 Erlotinib GDSC2 0.0100 10.0000
SUP-B8 FEN1_3940 GDSC1 0.0391 10.0000
SUP-B8 FGFR_0939 GDSC1 0.0098 2.5000
SUP-B8 FGFR_3831 GDSC1 0.0391 10.0000
SUP-B8 Foretinib GDSC2 0.0100 10.0000
SUP-B8 FS106 GDSC1 0.0391 10.0000
SUP-B8 FS112 GDSC1 0.0195 5.0000
SUP-B8 Fulvestrant GDSC1,GDSC2 0.0010 10.0000
SUP-B8 FY012 GDSC1 0.0391 10.0000
SUP-B8 FY026 GDSC1 0.0391 10.0000
SUP-B8 FY069 GDSC1 0.0391 10.0000
SUP-B8 GDC0810 GDSC2 0.0100 10.0000
SUP-B8 Gefitinib GDSC1,GDSC2 0.0020 2.0000
SUP-B8 Gemcitabine GDSC1,GDSC2 0.0002 10.0000
SUP-B8 GNE-317 GDSC2 0.0100 10.0000
SUP-B8 GSK-J4 GDSC1 0.1172 30.0000
SUP-B8 GSK1904529A GDSC2 0.0050 5.0000
SUP-B8 GSK2578215A GDSC2 0.0100 10.0000
SUP-B8 GSK2606414 GDSC2 0.0100 10.0000
SUP-B8 GSK269962A GDSC1,GDSC2 0.0100 10.0000
SUP-B8 GSK343 GDSC2 0.0010 1.0000
SUP-B8 GSK591 GDSC2 0.0100 10.0000
SUP-B8 GW441756 GDSC1,GDSC2 0.0020 2.0000
SUP-B8 I-BET-762 GDSC2 0.0100 10.0000
SUP-B8 I-BET151 GDSC1 0.0391 10.0000
SUP-B8 I-BRD9 GDSC2 0.0100 10.0000
SUP-B8 I-CBP112 GDSC1 0.0391 10.0000
SUP-B8 IAP_5620 GDSC1 0.0391 10.0000
SUP-B8 IAP_7638 GDSC1 0.0391 10.0000
SUP-B8 Ibrutinib GDSC2 0.0100 10.0000
SUP-B8 ICL1100013 GDSC1 0.0781 20.0000
SUP-B8 IGFR_3801 GDSC1 0.0391 10.0000
SUP-B8 IOX2 GDSC1,GDSC2 0.0004 0.5000
SUP-B8 Ipatasertib GDSC2 0.0100 10.0000
SUP-B8 Irinotecan GDSC2 0.0050 5.0000
SUP-B8 IWP-2 GDSC2 0.0010 1.0000
SUP-B8 JAK1_3715 GDSC1 0.0391 10.0000
SUP-B8 JAK3_7406 GDSC1 0.0391 10.0000
SUP-B8 JNK Inhibitor VIII GDSC1,GDSC2 0.0100 10.0000
SUP-B8 JQ1 GDSC1,GDSC2 0.0039 10.0000
SUP-B8 KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
SUP-B8 KU-55933 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 KU-60019 GDSC1 0.0391 10.0000
SUP-B8 Lapatinib GDSC2 0.0100 10.0000
SUP-B8 LCL161 GDSC2 0.0100 10.0000
SUP-B8 Leflunomide GDSC2 0.1001 100.0000
SUP-B8 Lenalidomide GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Lestaurtinib GDSC1,GDSC2 0.0020 2.0000
SUP-B8 LGK974 GDSC2 0.0100 10.0000
SUP-B8 Linsitinib GDSC2 0.0100 10.0000
SUP-B8 LJI308 GDSC2 0.0100 10.0000
SUP-B8 Luminespib GDSC2 0.0003 0.2500
SUP-B8 LY2109761 GDSC2 0.0050 5.0000
SUP-B8 MCT1_6447 GDSC1 0.0391 10.0000
SUP-B8 MCT4_1422 GDSC1 0.0391 10.0000
SUP-B8 Methotrexate GDSC1,GDSC2 0.0008 1.0000
SUP-B8 MG-132 GDSC2 0.0040 4.0000
SUP-B8 MIRA-1 GDSC2 0.0100 10.0000
SUP-B8 Mirin GDSC1,GDSC2 0.1001 100.0000
SUP-B8 MK-1775 GDSC2 0.0100 10.0000
SUP-B8 MK-2206 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 MK-8776 GDSC2 0.0050 5.0000
SUP-B8 ML323 GDSC2 0.0200 20.0000
SUP-B8 MN-64 GDSC2 0.0100 10.0000
SUP-B8 Motesanib GDSC1,GDSC2 0.0078 10.0000
SUP-B8 N22899-6-C1 GDSC1 0.0391 10.0000
SUP-B8 N23918-95-7 GDSC1 0.0391 10.0000
SUP-B8 N24798-49-A1 GDSC1 0.0391 10.0000
SUP-B8 Navitoclax GDSC1,GDSC2 0.0020 2.0000
SUP-B8 Nilotinib GDSC1,GDSC2 0.0078 10.0000
SUP-B8 Niraparib GDSC2 0.0100 10.0000
SUP-B8 NU7441 GDSC1,GDSC2 0.0078 10.0000
SUP-B8 Nutlin-3a GDSC1,GDSC2 0.0100 10.0000
SUP-B8 NVP-ADW742 GDSC2 0.0100 10.0000
SUP-B8 OF-1 GDSC2 0.0100 10.0000
SUP-B8 Olaparib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 OSI-027 GDSC2 0.0100 10.0000
SUP-B8 Osimertinib GDSC2 0.0010 1.0000
SUP-B8 OTX015 GDSC2 0.0100 10.0000
SUP-B8 Oxaliplatin GDSC2 0.0100 10.0000
SUP-B8 P22077 GDSC2 0.0100 10.0000
SUP-B8 Paclitaxel GDSC2 0.0001 0.1000
SUP-B8 Palbociclib GDSC1,GDSC2 0.0040 4.0000
SUP-B8 PARP_0108 GDSC1 0.0098 2.5000
SUP-B8 PARP_9482 GDSC1 0.0098 2.5000
SUP-B8 PARP_9495 GDSC1 0.0098 2.5000
SUP-B8 PCI-34051 GDSC2 0.0100 10.0000
SUP-B8 PD0325901 GDSC1,GDSC2 0.0010 2.5000
SUP-B8 PD173074 GDSC1,GDSC2 0.0078 10.0000
SUP-B8 Pevonedistat GDSC1,GDSC2 0.0039 10.0000
SUP-B8 PF-4708671 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 PFI-1 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 PFI3 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 PI3Ka_4409 GDSC1 0.0391 10.0000
SUP-B8 Picolinici-acid GDSC2 0.0100 10.0000
SUP-B8 Pictilisib GDSC1,GDSC2 0.0040 4.0000
SUP-B8 Piperlongumine GDSC1,GDSC2 0.0100 10.0000
SUP-B8 PLK_6522 GDSC1 0.0024 0.6250
SUP-B8 PLX-4720 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 PRIMA-1MET GDSC2 0.0300 30.0000
SUP-B8 PRT062607 GDSC2 0.0100 10.0000
SUP-B8 Pyridostatin GDSC2 0.0100 10.0000
SUP-B8 RAF_9304 GDSC1 0.0391 10.0000
SUP-B8 Rapamycin GDSC2 0.0001 0.1000
SUP-B8 Refametinib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Ribociclib GDSC2 0.0020 2.0000
SUP-B8 RO-3306 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 rTRAIL GDSC1 0.0004 0.1000
SUP-B8 Rucaparib GDSC1,GDSC2 0.0050 5.0000
SUP-B8 Ruxolitinib GDSC2 0.0100 10.0000
SUP-B8 RVX-208 GDSC2 0.0100 10.0000
SUP-B8 Sabutoclax GDSC2 0.0100 10.0000
SUP-B8 Sapitinib GDSC2 0.0050 5.0000
SUP-B8 Savolitinib GDSC2 0.0010 1.0000
SUP-B8 SB216763 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 SB505124 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 SB590885 GDSC1,GDSC2 0.0050 5.0000
SUP-B8 SCH772984 GDSC2 0.0050 5.0000
SUP-B8 Selumetinib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Sepantronium bromide GDSC2 0.0100 10.0000
SUP-B8 Serdemetan GDSC1,GDSC2 0.0100 10.0000
SUP-B8 SGC0946 GDSC1,GDSC2 0.0005 0.5000
SUP-B8 SL0101 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 SN-38 GDSC1,GDSC2 0.0002 10.0000
SUP-B8 Sorafenib GDSC2 0.0100 10.0000
SUP-B8 Staurosporine GDSC2 0.0078 2.0000
SUP-B8 Talazoparib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Tamoxifen GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Tanespimycin GDSC1,GDSC2 0.0010 1.0000
SUP-B8 TANK_1366 GDSC1 0.0098 2.5000
SUP-B8 Taselisib GDSC2 0.0100 10.0000
SUP-B8 Telomerase Inhibitor IX GDSC2 0.0100 10.0000
SUP-B8 Temozolomide GDSC1,GDSC2 0.0300 30.0000
SUP-B8 Temsirolimus GDSC1,GDSC2 0.0008 1.0000
SUP-B8 Tozasertib GDSC2 0.0050 5.0000
SUP-B8 Trametinib GDSC1,GDSC2 0.0010 1.0000
SUP-B8 Tretinoin GDSC1,GDSC2 0.0100 10.0000
SUP-B8 TTK_3146 GDSC1 0.0391 10.0000
SUP-B8 TW 37 GDSC1 0.0195 5.0000
SUP-B8 Ulixertinib GDSC2 0.0100 10.0000
SUP-B8 UNC0638 GDSC1 0.0781 20.0000
SUP-B8 UNC0642 GDSC1 0.0020 0.5000
SUP-B8 UNC1215 GDSC1 0.0039 1.0000
SUP-B8 Uprosertib GDSC2 0.0100 10.0000
SUP-B8 VE-822 GDSC2 0.0050 5.0000
SUP-B8 VE821 GDSC2 0.0100 10.0000
SUP-B8 Veliparib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Venetoclax GDSC2 0.0010 1.0000
SUP-B8 Vinblastine GDSC1 0.0004 0.1000
SUP-B8 Vinorelbine GDSC2 0.0001 0.1000
SUP-B8 Vismodegib GDSC1,GDSC2 0.0100 10.0000
SUP-B8 Vorinostat GDSC1,GDSC2 0.0100 10.0000
SUP-B8 VX-11e GDSC2 0.0100 10.0000
SUP-B8 VX-702 GDSC1 0.0078 2.0000
SUP-B8 Wee1 Inhibitor GDSC1,GDSC2 0.0078 10.0000
SUP-B8 WEHI-539 GDSC2 0.0100 10.0000
SUP-B8 WIKI4 GDSC2 0.0100 10.0000
SUP-B8 Wnt-C59 GDSC2 0.0100 10.0000
SUP-B8 WZ4003 GDSC2 0.0100 10.0000
SUP-B8 XAV939 GDSC1,GDSC2 0.0050 5.0000
SUP-B8 YK-4-279 GDSC1,GDSC2 0.0100 10.0000
SUP-B8 ZL049 GDSC1 0.0391 10.0000
SUP-B8 ZL109 GDSC1 0.0391 10.0000
SUP-B8 ZM447439 GDSC1,GDSC2 0.0100 10.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC