Cell Line : NK-92MI

Cellosaurus Index : CVCL_3755
Cellosaurus ID : NK-92MI

GDSC1 Name , GDSC2 Name : NK-92MI
CCLE Name : NK92MI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE

Cancer Type : haematopoietic_and_lymphoid_tissue
Dataset : All

Drug Response Information

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Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
NK-92MI 5-Fluorouracil GDSC2 0.0200 20.0000
NK-92MI A-443654 GDSC1 0.0040 1.0240
NK-92MI A-770041 GDSC1 0.0200 5.1200
NK-92MI ABT737 GDSC2 0.0100 10.0000
NK-92MI ACY-1215 GDSC1 0.0781 20.0000
NK-92MI Afatinib GDSC2 0.0040 4.0000
NK-92MI Afuresertib GDSC2 0.0100 10.0000
NK-92MI AGI-5198 GDSC2 0.0100 10.0000
NK-92MI AGI-6780 GDSC1,GDSC2 0.0020 10.0000
NK-92MI AGK-2 GDSC2 0.0040 4.0000
NK-92MI AKT inhibitor VIII GDSC1 0.0100 10.2400
NK-92MI Alisertib GDSC1,GDSC2 0.0100 10.0000
NK-92MI Alpelisib GDSC2 0.0100 10.0000
NK-92MI AMG-319 GDSC2 0.0100 10.0000
NK-92MI Apitolisib GDSC1 0.0781 20.0000
NK-92MI Ara-G GDSC1 0.0781 20.0000
NK-92MI ARRY-520 GDSC1 0.0010 0.2560
NK-92MI AS601245 GDSC1 0.0312 8.0000
NK-92MI AS605240 GDSC1 0.0781 20.0000
NK-92MI AST-1306 GDSC1 0.0781 20.0000
NK-92MI AT-7519 GDSC1 0.0400 10.2400
NK-92MI AT13148 GDSC2 0.0080 8.0000
NK-92MI AT7867 GDSC1 0.0781 20.0000
NK-92MI Avagacestat GDSC2 0.0100 10.0000
NK-92MI Axitinib GDSC2 0.0100 10.0000
NK-92MI AZ6102 GDSC2 0.0100 10.0000
NK-92MI AZ628 GDSC1 0.0156 4.0000
NK-92MI AZ960 GDSC2 0.0100 10.0000
NK-92MI AZD3759 GDSC2 0.0010 1.0000
NK-92MI AZD4547 GDSC2 0.0100 10.0000
NK-92MI AZD5363 GDSC2 0.0100 10.0000
NK-92MI AZD5582 GDSC2 0.0100 10.0000
NK-92MI AZD6482 GDSC1,GDSC2 0.0100 10.0000
NK-92MI AZD6738 GDSC2 0.0100 10.0000
NK-92MI AZD7762 GDSC2 0.0010 2.0000
NK-92MI AZD8186 GDSC2 0.0100 10.0000
NK-92MI BAM7 GDSC1 0.0781 20.0000
NK-92MI BAY-61-3606 GDSC1 0.0312 8.0000
NK-92MI Bexarotene GDSC1 0.0312 8.0000
NK-92MI BI-2536 GDSC1,GDSC2 0.0005 0.5000
NK-92MI BIBF-1120 GDSC1 0.0781 20.0000
NK-92MI BIBR-1532 GDSC2 0.0100 10.0000
NK-92MI Bicalutamide GDSC1,GDSC2 0.0040 10.0000
NK-92MI Bleomycin GDSC1 0.2500 64.0000
NK-92MI BMS-345541 GDSC1,GDSC2 0.0100 16.0000
NK-92MI BMS-509744 GDSC1 0.0400 10.2400
NK-92MI BMS-536924 GDSC1,GDSC2 0.0100 10.0000
NK-92MI BMS-754807 GDSC1,GDSC2 0.0100 10.0000
NK-92MI Bortezomib GDSC1,GDSC2 0.0000 0.0200
NK-92MI Bosutinib GDSC2 0.0020 2.0000
NK-92MI Brivanib, BMS-540215 GDSC1 0.0781 20.0000
NK-92MI Bryostatin 1 GDSC1 0.0000 0.0080
NK-92MI Buparlisib GDSC2 0.0100 10.0000
NK-92MI BX-912 GDSC1 0.0400 10.2400
NK-92MI BX795 GDSC2 0.0100 10.0000
NK-92MI C-75 GDSC1 0.0781 20.0000
NK-92MI Camptothecin GDSC2 0.0001 0.1000
NK-92MI CAP-232, TT-232, TLN-232 GDSC1 0.0781 20.0000
NK-92MI CAY10566 GDSC1 0.0100 2.5600
NK-92MI CCT-018159 GDSC2 0.0100 10.0000
NK-92MI CCT007093 GDSC2 0.0100 10.0000
NK-92MI CD532 GDSC1 0.0200 5.1200
NK-92MI Cediranib GDSC2 0.0100 10.0000
NK-92MI CGP-082996 GDSC1 0.0200 5.1200
NK-92MI CGP-60474 GDSC1 0.0010 0.2560
NK-92MI CHIR-99021 GDSC1,GDSC2 0.0100 10.0000
NK-92MI CI-1033 GDSC1 0.0781 20.0000
NK-92MI CMK GDSC1 0.0156 4.0000
NK-92MI CP466722 GDSC1 0.0625 16.0000
NK-92MI CPI-613 GDSC1 1.0000 256.0000
NK-92MI Crizotinib GDSC1,GDSC2 0.0040 8.0000
NK-92MI Cyclopamine GDSC1 0.0625 16.0000
NK-92MI Cyclophosphamide GDSC2 0.0100 10.0000
NK-92MI CZC24832 GDSC2 0.0100 10.0000
NK-92MI Dabrafenib GDSC2 0.0100 10.0000
NK-92MI Dacinostat GDSC1 0.0040 1.0240
NK-92MI Dactinomycin GDSC2 0.0008 0.8000
NK-92MI Dactolisib GDSC2 0.0003 0.2500
NK-92MI Daporinad GDSC2 0.0010 1.0000
NK-92MI Dasatinib GDSC1,GDSC2 0.0020 2.0000
NK-92MI Dinaciclib GDSC2 0.0010 1.0000
NK-92MI DMOG GDSC1 15.6250 4000.0000
NK-92MI Docetaxel GDSC2 0.0000 0.0125
NK-92MI Doramapimod GDSC2 0.0100 10.0000
NK-92MI Doxorubicin GDSC1 0.0040 1.0240
NK-92MI eEF2K Inhibitor, A-484954 GDSC1 0.0781 20.0000
NK-92MI EHT-1864 GDSC2 0.0100 10.0000
NK-92MI Elesclomol GDSC2 0.0002 0.2000
NK-92MI Embelin GDSC1 0.1250 32.0000
NK-92MI Entinostat GDSC1,GDSC2 0.0100 10.0000
NK-92MI Entospletinib GDSC2 0.0100 10.0000
NK-92MI Enzastaurin GDSC1 0.0781 20.0000
NK-92MI Epirubicin GDSC2 0.0100 10.0000
NK-92MI Epothilone B GDSC1 0.0001 0.0320
NK-92MI EPZ004777 GDSC2 0.0100 10.0000
NK-92MI EPZ5676 GDSC2 0.0100 10.0000
NK-92MI Erlotinib GDSC1,GDSC2 0.0078 10.0000
NK-92MI Etoposide GDSC1 0.0625 16.0000
NK-92MI ETP-45835 GDSC1 0.0781 20.0000
NK-92MI FH535 GDSC1 0.1250 32.0000
NK-92MI Flavopiridol GDSC1 0.0100 2.5600
NK-92MI FMK GDSC1 0.0781 20.0000
NK-92MI Foretinib GDSC2 0.0100 10.0000
NK-92MI FTI-277 GDSC1 0.0040 1.0240
NK-92MI FTY-720 GDSC1 0.0781 20.0000
NK-92MI Fulvestrant GDSC2 0.0010 1.0000
NK-92MI GDC0810 GDSC2 0.0100 10.0000
NK-92MI Gefitinib GDSC2 0.0020 2.0000
NK-92MI Gemcitabine GDSC1,GDSC2 0.0040 10.0000
NK-92MI Genentech Cpd 10 GDSC1 0.0400 10.2400
NK-92MI GNE-317 GDSC2 0.0100 10.0000
NK-92MI GNF-2 GDSC1 0.0050 1.2800
NK-92MI GSK1059615 GDSC1 0.0781 20.0000
NK-92MI GSK1070916 GDSC1 0.0100 2.5600
NK-92MI GSK1904529A GDSC1,GDSC2 0.0040 5.0000
NK-92MI GSK2578215A GDSC2 0.0100 10.0000
NK-92MI GSK2606414 GDSC2 0.0100 10.0000
NK-92MI GSK269962A GDSC1,GDSC2 0.0098 10.0000
NK-92MI GSK319347A GDSC1 0.0195 5.0000
NK-92MI GSK343 GDSC2 0.0010 1.0000
NK-92MI GSK429286A GDSC1 0.0781 20.0000
NK-92MI GSK591 GDSC2 0.0100 10.0000
NK-92MI GSK650394 GDSC1 0.0625 16.0000
NK-92MI GW441756 GDSC2 0.0020 2.0000
NK-92MI GW843682X GDSC1 0.0010 0.2560
NK-92MI HG6-64-1 GDSC1 0.0200 5.1200
NK-92MI I-BET-762 GDSC2 0.0100 10.0000
NK-92MI I-BRD9 GDSC2 0.0100 10.0000
NK-92MI Ibrutinib GDSC2 0.0100 10.0000
NK-92MI IC-87114 GDSC1 0.0781 20.0000
NK-92MI Idelalisib GDSC1 0.0781 20.0000
NK-92MI Imatinib GDSC1 0.0078 2.0000
NK-92MI IMD-0354 GDSC1 0.0781 20.0000
NK-92MI IOX2 GDSC2 0.0005 0.5000
NK-92MI IPA-3 GDSC1 0.1250 32.0000
NK-92MI Ipatasertib GDSC2 0.0100 10.0000
NK-92MI Irinotecan GDSC2 0.0050 5.0000
NK-92MI Ispinesib Mesylate GDSC1 0.0005 0.1280
NK-92MI IWP-2 GDSC2 0.0010 1.0000
NK-92MI JNJ38877605 GDSC1 0.0781 20.0000
NK-92MI JNK Inhibitor VIII GDSC2 0.0100 10.0000
NK-92MI JNK-9L GDSC1 0.0200 5.1200
NK-92MI JQ1 GDSC1,GDSC2 0.0100 10.0000
NK-92MI JQ12 GDSC1 0.0200 5.1200
NK-92MI JW-7-52-1 GDSC1 0.0047 1.2000
NK-92MI kb NB 142-70 GDSC1 0.0781 20.0000
NK-92MI KIN001-042 GDSC1 0.0400 10.2400
NK-92MI Kobe2602 GDSC1 0.0781 20.0000
NK-92MI KRAS (G12C) Inhibitor-12 GDSC2 0.0200 20.0000
NK-92MI KU-55933 GDSC2 0.0100 10.0000
NK-92MI Lapatinib GDSC1,GDSC2 0.0078 10.0000
NK-92MI LCL161 GDSC2 0.0100 10.0000
NK-92MI Leflunomide GDSC2 0.1001 100.0000
NK-92MI Lenalidomide GDSC2 0.0100 10.0000
NK-92MI Lestaurtinib GDSC2 0.0020 2.0000
NK-92MI LFM-A13 GDSC1 0.0625 16.0000
NK-92MI LGK974 GDSC2 0.0100 10.0000
NK-92MI LIMK1 inhibitor BMS4 GDSC1 0.0781 20.0000
NK-92MI Linsitinib GDSC1,GDSC2 0.0100 10.0000
NK-92MI LJI308 GDSC2 0.0100 10.0000
NK-92MI Luminespib GDSC1,GDSC2 0.0003 0.2560
NK-92MI LY2109761 GDSC2 0.0050 5.0000
NK-92MI MetAP2 Inhibitor, A832234 GDSC1 0.0100 2.5600
NK-92MI Methotrexate GDSC2 0.0010 1.0000
NK-92MI MG-132 GDSC1,GDSC2 0.0039 4.0000
NK-92MI Midostaurin GDSC1 0.0020 0.5120
NK-92MI MIRA-1 GDSC2 0.0100 10.0000
NK-92MI Mirin GDSC2 0.1001 100.0000
NK-92MI Mitomycin-C GDSC1 0.0625 16.0000
NK-92MI MK-1775 GDSC2 0.0100 10.0000
NK-92MI MK-2206 GDSC2 0.0100 10.0000
NK-92MI MK-8776 GDSC2 0.0050 5.0000
NK-92MI ML323 GDSC2 0.0200 20.0000
NK-92MI MN-64 GDSC2 0.0100 10.0000
NK-92MI Motesanib GDSC2 0.0100 10.0000
NK-92MI Navitoclax GDSC2 0.0020 2.0000
NK-92MI Nilotinib GDSC2 0.0100 10.0000
NK-92MI Niraparib GDSC2 0.0100 10.0000
NK-92MI NSC-87877 GDSC1 0.0625 16.0000
NK-92MI NU7441 GDSC2 0.0100 10.0000
NK-92MI Nutlin-3a GDSC2 0.0100 10.0000
NK-92MI NVP-ADW742 GDSC2 0.0100 10.0000
NK-92MI NVP-TAE684 GDSC1 0.0078 2.0000
NK-92MI Obatoclax Mesylate GDSC1 0.0625 16.0000
NK-92MI OF-1 GDSC2 0.0100 10.0000
NK-92MI Olaparib GDSC2 0.0100 10.0000
NK-92MI OSI-027 GDSC2 0.0100 10.0000
NK-92MI Osimertinib GDSC2 0.0010 1.0000
NK-92MI OSU-03012 GDSC1 0.0625 16.0000
NK-92MI OTX015 GDSC2 0.0100 10.0000
NK-92MI Oxaliplatin GDSC2 0.0100 10.0000
NK-92MI P22077 GDSC2 0.0100 10.0000
NK-92MI PAC-1 GDSC1 0.0100 2.5600
NK-92MI Paclitaxel GDSC1,GDSC2 0.0001 0.1024
NK-92MI Palbociclib GDSC2 0.0040 4.0000
NK-92MI Panobinostat GDSC1 0.0040 1.0240
NK-92MI Parthenolide GDSC1 0.0195 5.0000
NK-92MI Pazopanib GDSC1 0.0312 8.0000
NK-92MI PCI-34051 GDSC2 0.0100 10.0000
NK-92MI PD0325901 GDSC2 0.0025 2.5000
NK-92MI PD173074 GDSC2 0.0100 10.0000
NK-92MI Pemetrexed GDSC1 0.0100 2.5600
NK-92MI Pevonedistat GDSC2 0.0100 10.0000
NK-92MI PF-00299804 GDSC1 0.0781 20.0000
NK-92MI PF-4708671 GDSC2 0.0100 10.0000
NK-92MI PF-562271 GDSC1 0.0100 2.5600
NK-92MI PFI-1 GDSC2 0.0100 10.0000
NK-92MI PFI3 GDSC2 0.0100 10.0000
NK-92MI PHA-665752 GDSC1 0.0078 2.0000
NK-92MI Picolinici-acid GDSC2 0.0100 10.0000
NK-92MI Pictilisib GDSC2 0.0040 4.0000
NK-92MI Pilaralisib GDSC1 0.0781 20.0000
NK-92MI Piperlongumine GDSC2 0.0100 10.0000
NK-92MI PLX-4720 GDSC2 0.0100 10.0000
NK-92MI Ponatinib GDSC1 0.0020 0.5120
NK-92MI PRIMA-1MET GDSC2 0.0300 30.0000
NK-92MI PRT062607 GDSC2 0.0100 10.0000
NK-92MI Pyridostatin GDSC2 0.0100 10.0000
NK-92MI Pyrimethamine GDSC1 0.0781 20.0000
NK-92MI QL-XII-47 GDSC1 0.0400 10.2400
NK-92MI QS11 GDSC1 0.0400 10.2400
NK-92MI Rapamycin GDSC1,GDSC2 0.0001 0.1000
NK-92MI Refametinib GDSC2 0.0100 10.0000
NK-92MI Ribociclib GDSC2 0.0020 2.0000
NK-92MI RO-3306 GDSC2 0.0100 10.0000
NK-92MI RU-SKI 43 GDSC1 0.0781 20.0000
NK-92MI Rucaparib GDSC2 0.0050 5.0000
NK-92MI Ruxolitinib GDSC1,GDSC2 0.0100 10.0000
NK-92MI RVX-208 GDSC2 0.0100 10.0000
NK-92MI S-Trityl-L-cysteine GDSC1 0.0200 5.1200
NK-92MI Sabutoclax GDSC2 0.0100 10.0000
NK-92MI Salubrinal GDSC1 0.0625 16.0000
NK-92MI Sapitinib GDSC2 0.0050 5.0000
NK-92MI Saracatinib GDSC1 0.0078 2.0000
NK-92MI Savolitinib GDSC2 0.0010 1.0000
NK-92MI SB216763 GDSC2 0.0100 10.0000
NK-92MI SB505124 GDSC2 0.0100 10.0000
NK-92MI SB590885 GDSC2 0.0050 5.0000
NK-92MI SCH772984 GDSC2 0.0050 5.0000
NK-92MI Seliciclib GDSC1 0.0625 16.0000
NK-92MI Selumetinib GDSC2 0.0100 10.0000
NK-92MI Sepantronium bromide GDSC2 0.0100 10.0000
NK-92MI Serdemetan GDSC2 0.0100 10.0000
NK-92MI SGC0946 GDSC2 0.0005 0.5000
NK-92MI Shikonin GDSC1 0.0625 16.0000
NK-92MI SL0101 GDSC2 0.0100 10.0000
NK-92MI SN-38 GDSC2 0.0100 10.0000
NK-92MI Sorafenib GDSC1,GDSC2 0.0100 10.0000
NK-92MI Sphingosine Kinase 1 Inhibitor II GDSC1 0.0100 2.5600
NK-92MI Staurosporine GDSC2 0.0078 2.0000
NK-92MI SU11274 GDSC1 0.0400 10.2400
NK-92MI Sunitinib GDSC1 0.0312 8.0000
NK-92MI TAK-715 GDSC1 0.0781 20.0000
NK-92MI Talazoparib GDSC2 0.0100 10.0000
NK-92MI Tamoxifen GDSC2 0.0100 10.0000
NK-92MI Tanespimycin GDSC2 0.0010 1.0000
NK-92MI Taselisib GDSC2 0.0100 10.0000
NK-92MI Telomerase Inhibitor IX GDSC2 0.0100 10.0000
NK-92MI Temozolomide GDSC2 0.0300 30.0000
NK-92MI Temsirolimus GDSC2 0.0010 1.0000
NK-92MI Tenovin-6 GDSC1 0.0781 20.0000
NK-92MI TGX221 GDSC1 0.0391 10.0000
NK-92MI Thapsigargin GDSC1 0.0020 0.5120
NK-92MI Tipifarnib GDSC1 0.0625 16.0000
NK-92MI TL-2-105 GDSC1 0.0400 10.2400
NK-92MI Torin 2 GDSC1 0.0781 20.0000
NK-92MI Tozasertib GDSC1,GDSC2 0.0050 5.0000
NK-92MI Trametinib GDSC2 0.0010 1.0000
NK-92MI Tretinoin GDSC2 0.0100 10.0000
NK-92MI Trichostatin A GDSC1 0.0040 1.0240
NK-92MI TWS119 GDSC1 0.0781 20.0000
NK-92MI Ulixertinib GDSC2 0.0100 10.0000
NK-92MI Uprosertib GDSC2 0.0100 10.0000
NK-92MI VE-822 GDSC2 0.0050 5.0000
NK-92MI VE821 GDSC2 0.0100 10.0000
NK-92MI Veliparib GDSC2 0.0100 10.0000
NK-92MI Venetoclax GDSC2 0.0010 1.0000
NK-92MI Vinorelbine GDSC1,GDSC2 0.0001 0.1000
NK-92MI Vismodegib GDSC2 0.0100 10.0000
NK-92MI Vorinostat GDSC2 0.0100 10.0000
NK-92MI Voxtalisib GDSC1 0.0781 20.0000
NK-92MI VX-11e GDSC2 0.0100 10.0000
NK-92MI Wee1 Inhibitor GDSC2 0.0100 10.0000
NK-92MI WEHI-539 GDSC2 0.0100 10.0000
NK-92MI WH-4-023 GDSC1 0.0200 5.1200
NK-92MI WIKI4 GDSC2 0.0100 10.0000
NK-92MI Wnt-C59 GDSC2 0.0100 10.0000
NK-92MI WYE-125132 GDSC1 0.0400 10.2400
NK-92MI WZ-1-84 GDSC1 0.0400 10.2400
NK-92MI WZ4003 GDSC2 0.0100 10.0000
NK-92MI XAV939 GDSC2 0.0050 5.0000
NK-92MI XMD8-85 GDSC1 0.0312 8.0000
NK-92MI YK-4-279 GDSC2 0.0100 10.0000
NK-92MI Z-LLNle-CHO GDSC1 0.0100 2.5600
NK-92MI ZM447439 GDSC2 0.0100 10.0000
NK-92MI ZSTK474 GDSC1 0.0200 5.1200

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC