Cell Line : MALME-3M

Cellosaurus Index : CVCL_1438
Cellosaurus ID : MALME-3M

CTRP2 Name : MALME3M
CCLE Name : MALME3M_SKIN

Cancer Type : skin
Dataset : All

Drug Response Information

Click to show/hide information cards below or download all drug response information.

           

Information cards below will change according to the dataset selected. The default dataset is “All”, which means information in the cards is based on the integration. If “All” is not selected, information cards will contain drug response information preprocessed for each dataset independently.

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Experimental information

Experimental information from All dataset, including cell line name, drug name, and minimum and maximum dosages used in each experiment. Click on Dose-response to query more detail for each experiment.

Cellosaurus ID Drug Name Original Dataset(s) Min Dose Max Dose Dose-response
MALME-3M A-804598 CTRP2 0.0020 66.0000
MALME-3M AA-COCF3 CTRP2 0.0081 270.0000
MALME-3M ABT737 CTRP2 0.0011 37.0000
MALME-3M AEW541 CCLE 0.0025 8.0000
MALME-3M Alpelisib CTRP2 0.0020 66.0000
MALME-3M alvocidib CTRP2 0.0020 66.0000
MALME-3M apicidin CTRP2 0.0010 33.0000
MALME-3M AT-406 CTRP2 0.0020 66.0000
MALME-3M AT13387 CTRP2 0.0020 66.0000
MALME-3M austocystin D CTRP2 0.0011 37.0000
MALME-3M AZD-7545 CTRP2 0.0023 74.0000
MALME-3M AZD6482 CTRP2 0.0020 66.0000
MALME-3M AZD7762 CTRP2 0.0020 66.0000
MALME-3M AZD8055 CTRP2 0.0020 66.0000
MALME-3M bardoxolone methyl CTRP2 0.0020 66.0000
MALME-3M Belinostat CTRP2 0.0020 66.0000
MALME-3M BI-2536 CTRP2 0.0010 33.0000
MALME-3M birinapant CTRP2 0.0020 66.0000
MALME-3M BIX-01294 CTRP2 0.0010 33.0000
MALME-3M BMS-536924 CTRP2 0.0011 37.0000
MALME-3M Bortezomib CTRP2 0.0000 0.1300
MALME-3M Bosutinib CTRP2 0.0020 66.0000
MALME-3M BRD-A02303741:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M BRD-K01737880 CTRP2 0.0020 66.0000
MALME-3M BRD-K07442505 CTRP2 0.0020 66.0000
MALME-3M BRD-K14844214 CTRP2 0.0020 66.0000
MALME-3M BRD-K24690302 CTRP2 0.0020 66.0000
MALME-3M BRD-K33199242 CTRP2 0.0020 67.0000
MALME-3M BRD-K34222889 CTRP2 0.0017 57.0000
MALME-3M BRD-K35604418 CTRP2 0.0081 270.0000
MALME-3M BRD-K37390332 CTRP2 0.0010 33.0000
MALME-3M BRD-K45681478 CTRP2 0.0020 66.0000
MALME-3M BRD-K51831558 CTRP2 0.0020 66.0000
MALME-3M BRD-K63431240 CTRP2 0.0009 30.0000
MALME-3M BRD-K64610608 CTRP2 0.0010 33.0000
MALME-3M BRD-K66532283 CTRP2 0.0020 66.0000
MALME-3M BRD-K71781559 CTRP2 0.0020 66.0000
MALME-3M BRD-K80183349 CTRP2 0.0020 66.0000
MALME-3M BRD-K94991378 CTRP2 0.0025 83.0000
MALME-3M BRD-K97651142 CTRP2 0.0020 66.0000
MALME-3M BRD-M00053801 CTRP2 0.0020 66.0000
MALME-3M BRD8958 CTRP2 0.0020 66.0000
MALME-3M BRD9876:MK-1775 (4:1 mol-mol) CTRP2 0.0020 66.0000
MALME-3M brefeldin A CTRP2 0.0011 37.0000
MALME-3M C6-ceramide CTRP2 0.0020 66.0000
MALME-3M Cabozantinib CTRP2 0.0020 66.0000
MALME-3M canertinib CTRP2 0.0020 66.0000
MALME-3M carboplatin:etoposide (40:17 mol-mol) CTRP2 0.0014 48.0000
MALME-3M carboplatin:UNC0638 (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M cerulenin CTRP2 0.0045 150.0000
MALME-3M chlorambucil CTRP2 0.0081 270.0000
MALME-3M ciclopirox CTRP2 0.0020 66.0000
MALME-3M ciclosporin CTRP2 0.0010 33.0000
MALME-3M compound 1B CTRP2 0.0020 66.0000
MALME-3M Compound 7d-cis CTRP2 0.0010 33.0000
MALME-3M Crizotinib CTRP2,CCLE 0.0020 66.0000
MALME-3M cucurbitacin I CTRP2 0.0010 33.0000
MALME-3M cytarabine hydrochloride CTRP2 0.0020 66.0000
MALME-3M cytochalasin B CTRP2 0.0010 33.0000
MALME-3M Dabrafenib CTRP2 0.0020 66.0000
MALME-3M Dactolisib CTRP2 0.0005 17.0000
MALME-3M DBeQ CTRP2 0.0020 66.0000
MALME-3M decitabine:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M Dinaciclib CTRP2 0.0020 66.0000
MALME-3M Docetaxel CTRP2 0.0020 66.0000
MALME-3M docetaxel:tanespimycin (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M Doxorubicin CTRP2 0.0020 66.0000
MALME-3M doxorubicin:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M Entinostat CTRP2 0.0020 66.0000
MALME-3M Erlotinib CTRP2,CCLE 0.0020 66.0000
MALME-3M erlotinib:PLX-4032 (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M etomoxir CTRP2 0.0090 300.0000
MALME-3M Etoposide CTRP2 0.0009 28.0000
MALME-3M ETP-46464 CTRP2 0.0020 66.0000
MALME-3M fluorouracil CTRP2 0.0041 130.0000
MALME-3M Foretinib CTRP2 0.0020 66.0000
MALME-3M FQI-2 CTRP2 0.0010 33.0000
MALME-3M fumonisin B1 CTRP2 0.0150 500.0000
MALME-3M GANT-61 CTRP2 0.0020 66.0000
MALME-3M GDC-0879 CTRP2 0.0020 66.0000
MALME-3M Gefitinib CTRP2 0.0020 66.0000
MALME-3M Gemcitabine CTRP2 0.0010 33.0000
MALME-3M GMX-1778 CTRP2 0.0000 0.3000
MALME-3M gossypol CTRP2 0.0011 37.0000
MALME-3M GSK1059615 CTRP2 0.0010 33.0000
MALME-3M GSK2636771 CTRP2 0.0020 66.0000
MALME-3M GSK461364 CTRP2 0.0020 66.0000
MALME-3M HBX-41108 CTRP2 0.0020 66.0000
MALME-3M I-BET-762 CTRP2 0.0020 66.0000
MALME-3M Ibrutinib CTRP2 0.0020 66.0000
MALME-3M IC-87114 CTRP2 0.0020 66.0000
MALME-3M Idelalisib CTRP2 0.0020 66.0000
MALME-3M Imatinib CTRP2 0.0020 66.0000
MALME-3M indisulam CTRP2 0.0010 33.0000
MALME-3M Irinotecan CCLE 0.0025 8.0000
MALME-3M isonicotinohydroxamic acid CTRP2 0.0010 33.0000
MALME-3M ISOX CTRP2 0.0010 33.0000
MALME-3M ISOX:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
MALME-3M JQ-1:carboplatin (1:1 mol-mol) CTRP2 0.0020 66.0000
MALME-3M JQ-1:MK-0752 (1:1 mol-mol) CTRP2 0.0020 66.0000
MALME-3M JQ-1:navitoclax (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M JQ-1:UNC0638 (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M JQ-1:vorinostat (2:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M JQ1 CTRP2 0.0020 66.0000
MALME-3M JW-74 CTRP2 0.0020 66.0000
MALME-3M KH-CB19 CTRP2 0.0005 17.0000
MALME-3M KPT185 CTRP2 0.0020 66.0000
MALME-3M KU-0063794 CTRP2 0.0020 66.0000
MALME-3M KU-60019 CTRP2 0.0020 66.0000
MALME-3M KX2-391 CTRP2 0.0020 66.0000
MALME-3M L-685458 CTRP2,CCLE 0.0011 37.0000
MALME-3M Lapatinib CCLE 0.0025 8.0000
MALME-3M LBH-589 CTRP2 0.0020 66.0000
MALME-3M LBW242 CCLE 0.0025 8.0000
MALME-3M leptomycin B CTRP2 0.0020 66.0000
MALME-3M Linifanib CTRP2 0.0020 66.0000
MALME-3M Linsitinib CTRP2 0.0010 33.0000
MALME-3M lomeguatrib CTRP2 0.0020 66.0000
MALME-3M lovastatin acid CTRP2 0.0041 130.0000
MALME-3M LRRK2-IN-1 CTRP2 0.0020 66.0000
MALME-3M marinopyrrole A CTRP2 0.0020 66.0000
MALME-3M Methotrexate CTRP2 0.0020 66.0000
MALME-3M MGCD-265 CTRP2 0.0020 66.0000
MALME-3M mitomycin CTRP2 0.0015 50.0000
MALME-3M MK-1775 CTRP2 0.0010 33.0000
MALME-3M MK-2206 CTRP2 0.0010 33.0000
MALME-3M ML050 CTRP2 0.0020 66.0000
MALME-3M ML210 CTRP2 0.0010 33.0000
MALME-3M ML311 CTRP2 0.0010 66.0000
MALME-3M ML334 diastereomer CTRP2 0.0041 130.0000
MALME-3M MLN2480 CTRP2 0.0020 66.0000
MALME-3M momelotinib CTRP2 0.0020 66.0000
MALME-3M nakiterpiosin CTRP2 0.0010 33.0000
MALME-3M narciclasine CTRP2 0.0010 33.0000
MALME-3M Navitoclax CTRP2 0.0010 33.0000
MALME-3M navitoclax:birinapant (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:gemcitabine (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:MST-312 (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:piperlongumine (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:pluripotin (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:PLX-4032 (1:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M navitoclax:sorafenib (1:1 mol-mol) CTRP2 0.0015 50.0000
MALME-3M Nelarabine CTRP2 0.0020 66.0000
MALME-3M Nilotinib CCLE 0.0025 8.0000
MALME-3M NPC-26 CTRP2 0.0012 40.0000
MALME-3M Nutlin-3a CCLE 0.0025 8.0000
MALME-3M NVP-ADW742 CTRP2 0.0020 66.0000
MALME-3M NVP-BSK805 CTRP2 0.0020 66.0000
MALME-3M NVP-TAE684 CCLE 0.0025 8.0000
MALME-3M Obatoclax Mesylate CTRP2 0.0020 66.0000
MALME-3M oligomycin A CTRP2 0.0010 33.0000
MALME-3M omacetaxine mepesuccinate CTRP2 0.0020 66.0000
MALME-3M OSI-027 CTRP2 0.0020 66.0000
MALME-3M OSI-930 CTRP2 0.0020 66.0000
MALME-3M PAC-1 CTRP2 0.0010 33.0000
MALME-3M Paclitaxel CTRP2,CCLE 0.0020 66.0000
MALME-3M Palbociclib CCLE 0.0025 8.0000
MALME-3M palmostatin B CTRP2 0.0020 66.0000
MALME-3M Panobinostat CCLE 0.0025 8.0000
MALME-3M parbendazole CTRP2 0.0020 66.0000
MALME-3M PD 153035 CTRP2 0.0010 33.0000
MALME-3M PD0325901 CCLE 0.0025 8.0000
MALME-3M PD318088 CTRP2 0.0020 66.0000
MALME-3M PF-3758309 CTRP2 0.0020 66.0000
MALME-3M PHA-665752 CCLE 0.0025 8.0000
MALME-3M PI-103 CTRP2 0.0011 37.0000
MALME-3M Pictilisib CTRP2 0.0020 66.0000
MALME-3M PIK-93 CTRP2 0.0020 66.0000
MALME-3M Piperlongumine CTRP2 0.0010 33.0000
MALME-3M pitstop2 CTRP2 0.0020 66.0000
MALME-3M Platin CTRP2 0.0020 66.0000
MALME-3M pluripotin CTRP2 0.0010 33.0000
MALME-3M PLX-4032 CTRP2 0.0010 33.0000
MALME-3M PLX-4720 CTRP2,CCLE 0.0010 33.0000
MALME-3M PRIMA-1 CTRP2 0.0051 170.0000
MALME-3M procarbazine CTRP2 0.0020 66.0000
MALME-3M purmorphamine CTRP2 0.0046 150.0000
MALME-3M pyrazolanthrone CTRP2 0.0020 66.0000
MALME-3M R428 CTRP2 0.0020 66.0000
MALME-3M RAF265 CTRP2,CCLE 0.0020 66.0000
MALME-3M Rapamycin CTRP2 0.0010 33.0000
MALME-3M Repligen 136 CTRP2 0.0020 66.0000
MALME-3M RG-108 CTRP2 0.0081 270.0000
MALME-3M RO4929097 CTRP2 0.0020 66.0000
MALME-3M salermide:PLX-4032 (12:1 mol-mol) CTRP2 0.0066 220.0000
MALME-3M Saracatinib CCLE 0.0025 8.0000
MALME-3M SB-225002 CTRP2 0.0011 37.0000
MALME-3M SB-431542 CTRP2 0.0020 66.0000
MALME-3M SB-525334 CTRP2 0.0020 66.0000
MALME-3M SB-743921 CTRP2 0.0010 33.0000
MALME-3M Selumetinib CTRP2,CCLE 0.0025 270.0000
MALME-3M selumetinib:BRD-A02303741 (4:1 mol-mol) CTRP2 0.0051 170.0000
MALME-3M selumetinib:decitabine (4:1 mol-mol) CTRP2 0.0051 170.0000
MALME-3M selumetinib:GDC-0941 (4:1 mol-mol) CTRP2 0.0051 170.0000
MALME-3M selumetinib:JQ-1 (4:1 mol-mol) CTRP2 0.0051 170.0000
MALME-3M selumetinib:MK-2206 (8:1 mol-mol) CTRP2 0.0046 150.0000
MALME-3M selumetinib:piperlongumine (8:1 mol-mol) CTRP2 0.0046 150.0000
MALME-3M selumetinib:PLX-4032 (8:1 mol-mol) CTRP2 0.0046 150.0000
MALME-3M selumetinib:tretinoin (2:1 mol-mol) CTRP2 0.0061 200.0000
MALME-3M selumetinib:UNC0638 (4:1 mol-mol) CTRP2 0.0051 170.0000
MALME-3M selumetinib:vorinostat (8:1 mol-mol) CTRP2 0.0046 150.0000
MALME-3M semagacestat CTRP2 0.0020 66.0000
MALME-3M Sepantronium bromide CTRP2 0.0000 1.0000
MALME-3M Serdemetan CTRP2 0.0010 33.0000
MALME-3M silmitasertib CTRP2 0.0020 66.0000
MALME-3M sirolimus:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
MALME-3M SN-38 CTRP2 0.0000 1.3000
MALME-3M SNX-2112 CTRP2 0.0011 37.0000
MALME-3M Sorafenib CTRP2,CCLE 0.0020 66.0000
MALME-3M spautin-1 CTRP2 0.0020 66.0000
MALME-3M Sphingosine Kinase 1 Inhibitor II CTRP2 0.0010 33.0000
MALME-3M SR8278 CTRP2 0.0020 66.0000
MALME-3M STF-31 CTRP2 0.0020 66.0000
MALME-3M SU11274 CTRP2 0.0020 66.0000
MALME-3M Sunitinib CTRP2 0.0020 66.0000
MALME-3M SZ4TA2 CTRP2 0.0020 66.0000
MALME-3M Tanespimycin CCLE 0.0025 8.0000
MALME-3M tanespimycin:bortezomib (250:1 mol-mol) CTRP2 0.0005 17.0000
MALME-3M Telomerase Inhibitor IX CTRP2 0.0010 33.0000
MALME-3M Temozolomide CTRP2 0.0020 66.0000
MALME-3M TG-100-115 CTRP2 0.0020 66.0000
MALME-3M Thalidomide CTRP2 0.0020 66.0000
MALME-3M Tivozanib CTRP2 0.0010 33.0000
MALME-3M TKI258 CCLE 0.0025 8.0000
MALME-3M Topotecan CCLE 0.0025 8.0000
MALME-3M Trametinib CTRP2 0.0020 66.0000
MALME-3M Tretinoin CTRP2 0.0041 130.0000
MALME-3M tretinoin:carboplatin (2:1 mol-mol) CTRP2 0.0030 100.0000
MALME-3M tretinoin:navitoclax (4:1 mol-mol) CTRP2 0.0025 83.0000
MALME-3M triptolide CTRP2 0.0000 0.3000
MALME-3M TW 37 CTRP2 0.0010 33.0000
MALME-3M valdecoxib CTRP2 0.0180 600.0000
MALME-3M Vincristine CTRP2 0.0041 130.0000
MALME-3M vorinostat:navitoclax (4:1 mol-mol) CTRP2 0.0010 33.0000
MALME-3M VU0155056 CTRP2 0.0020 66.0000
MALME-3M VX-680 CTRP2 0.0020 66.0000
MALME-3M WP1130 CTRP2 0.0020 66.0000
MALME-3M ZD-6474 CCLE 0.0025 8.0000
MALME-3M zebularine CTRP2 0.0180 590.0000

IC50

IC50 indicates how much drug dosage is needed to inhibit the cells by 50%, in vitro, compared to the control well.

Drugs with highest and lowest IC50

IC90

IC90 indicates how much drug dosage is needed to inhibit the cells by 90%, in vitro, compared to the control well.

Drugs with highest and lowest IC90

AUC

AUC represents the area under a dose-response curve, where 0% indicates no activity and 100% indicates that a drug completely inhibits the cells across testing dosages.

Drugs with highest and lowest AUC